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Par

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A Multidisciplinary Approac h

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Paraganglioma

A Multidisciplinary Approach

Renato Mariani-Costantini

Editor

Codon Publications

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Cover image: A class C4Di2Vi tumor. See page 112, Chapter 6 for details.

Paraganglioma

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Paraganglioma

A Multidisciplinary Approach

Edited by

RENATO MARIANI-COSTANTINI, MD

Department of Medicine, Dentistry and Biotechnology, Unit of General

Pathology, Center for Aging Science and Translational Medicine (CeSI-MeT),

“G. d’Annunzio” University, Italy

Codon Publications

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Paraganglioma: A Multidisciplinary Approach

ISBN: 978-0-9944381-7-1

DOI: http://dx.doi.org/10.15586/paraganglioma.2019

Edited by

Renato Mariani-Costantini, MD, Department of Medicine, Dentistry and Biotechnology, Unit of General Pathology, Center for Aging Science and Translational Medicine (CeSI-MeT), “G. d’Annunzio” University, Italy

Published by

Codon Publications Brisbane, Australia

Copyright© 2019 Codon Publications

This open access book is published under Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). https://creativecommons.org/licenses/by-nc/4.0/

Users are allowed to share (copy and redistribute the material in any medium or format) and adapt (remix, transform, and build upon the material for any non-commercial purpose), as long as the authors and the publisher are explicitly identified and properly acknowledged as the original source.

Notice to the user

The views and opinions expressed in this book are believed to be accurate at the time of publi-cation. The publisher, editors or authors cannot be held responsible or liable for any errors, omissions or consequences arising from the use of the information contained in this book. The publisher makes no warranty, implicit or explicit, with respect to the contents of this book, or its use.

First Published in June 2019 Printed in Australia

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Contents

v

CONTENTS

Foreword vii

Preface ix

List of Contributors

xi

1 Genetics of Pheochromocytoma and Paraganglioma

1

Bernardo Dias Pereira, Henrique Vara Luiz, Ana Gonçalves Ferreira,

Jorge Portugal

2 Biochemical Diagnosis of Pheochromocytoma and

Paraganglioma 23

Ying Shen, Liming Cheng

3 Imaging of Pheochromocytoma and Paraganglioma

41

Malak Itani, Joyce Mhlanga

4 Surgical and Pharmacological Management of

Functioning Pheochromocytoma and Paraganglioma

63

Maria Isabel Del Olmo García, Rosana Palasí, Rosa Cámara Gómez,

José Luis Ponce Marco, Juan Francisco Merino-Torres

5 Carotid Body and Vagal Paragangliomas: Epidemiology,

Genetics, Clinicopathological Features, Imaging, and

Surgical Management

81

Sampath Chandra Prasad, Carlo Terenzio Paties, Mattia Russel Pantalone,

Renato Mariani-Costantini, Mario Sanna

6 Tympanojugular Paragangliomas: Surgical Management

and Clinicopathological Features

99

Sampath Chandra Prasad, Carlo Terenzio Paties, Francesca Schiavi,

Diana Liberata Esposito, Lavinia Vittoria Lotti, Renato Mariani-Costantini,

Mario Sanna

Index 125

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