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Nonsurgical genioplasty

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L E T T E R T O T H E E D I T O R

Nonsurgical genioplasty

Dear Editor,

Chin contributes to facial balance and harmony. Appropriate treat-ment of aesthetic deformities of the will often improves the appear-ance of the mouth, lips, and nose. Augmentation of the chin can be performed with injectable fillers or autologous fat, placement of an alloplastic chin implant, or with chin's bony osteotomy. Determining the best procedure for a patient requires careful consideration of his anatomy, as well as the risks and benefits of each treatment. Fillers offer a nonsurgical, nonpermanent method of correction of chin retrusion in the appropriate patient.

We describe a case series of 200 patients, which have been treated with chin corrections by means of VYC-20 hyaluronic acid in order to create a treatment algorithm for chin defects thereby record-ing technique, amount of filler and complication rate in our patients.

Seckel divided the face into seven functional danger zones. Danger Zone 3: Includes the marginal mandibular branch of the facial nerve, facial artery, and vein.

Danger Zone 7: Contains the mental nerve, which carries sensory innervation to ipsilateral chin and lower lip.

Focus on patient's examination. Preoperative photos were taken. Stop all blood-thinning agents starting 1 week prior to the proce-dure to reduce bruising.

The chin can be divided into six subunits using the MD Codes classification. Volumizing a single area often leads to inadequate aes-thetic results.

High G-prime, high viscosity hyaluronic acid (HA), was used. A 27-gauge needle can be used for deep injections subperiosteally, and we advise using blunt cannula to make refinements. The bimodal approach for filler injection into the chin can be beneficial doing deep injections to augment the mandibular structure, followed by injections in the subcutaneous fat layer to improve contouring. We used an average of 4 mL of high G-prime HA per patient.

Immediately after procedure, we gave ice pack for 30 min. We treated 200 patients (147 women, 53 men) aged 21–48 (aver-age 34.6 years old).

Follow-up: after 3 days, 1 week, 1 month, and 8 months.

Clinical photos were taken 2 weeks and 8 months after procedure. Side effects: see Table 1. Also, refer Figures 1 and 2.

HA fillers are used for their characteristics (Bertossi et al., 2013), if the patient does not like the result or if there are adverse effects hyal-uronidase can be used. At this point, a clear treatment plan is neces-sary to justify the possible choices offered to our patients after our clinical records.

In our study, we have used the Arnett's analysis (soft tissue cepha-lometric analysis (STCA); Arnett & Gunson, 1993).

F I G U R E 1 Before and after hyaluronic acid filler (left-side after, right-side before) frontal view

T A B L E 1 Complications during nonsurgical genioplasty Complication No. of patients Percentage

Bruising 15 7.5%

Swelling 11 5.5%

Edema 8 4%

Received: 11 October 2018 Revised: 28 December 2018 Accepted: 24 January 2019 DOI: 10.1111/dth.12874

Dermatologic Therapy. 2019;32:e12874. wileyonlinelibrary.com/journal/dth © 2019 Wiley Periodicals, Inc. 1 of 3 https://doi.org/10.1111/dth.12874

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With regard to complications, the chin region is considered a safer area, as very few cases of postfiller vascular complications have been reported in literature, skin necrosis and lingual necrosis were the worst.

Injection techniques such as pretunneling, use of a blunt cannula, aspiration before injection, slow injection, low-pressure injection, moving the needle while injecting, and use of a small bolus per injec-tion should be applied to minimize complicainjec-tions. Close and consis-tent observation of patients after filler injection is necessary. If signs and symptoms are observed, the patient must return and undergo fur-ther examination. Diagnosis and treatment should not be delayed.

The first-choice therapy for vascular occlusion due to HA is the use of hyaluronidase, an enzyme that catalyzes HA hydrolysis. Treat-ment is conducted with a focus on proper timing (DeLorenzi, 2017). Hyaluronidase should be immediately injected into the affected area once the diagnosis is confirmed (Fang, Rahman, & Kapoor, 2018), or even suspected. Delayed injection will undoubtedly be an obstacle to saving tissues from ischemia.

It is important to choose the right patient to maximize results and give him a predictable and stable outcome (Bertossi et al., 2015; Guyuron & Raszewski, 1990; Richard et al., 2001; Trauner & Obwegeser, 1957; White & Dufresne, 2011). The best results arrive when:

• Low sagittal deficiency or with mild asymmetry, with normal, mild, and reduction of soft-tissue chin thickness.

• Sagittal deficiency, with no asymmetry with mild or severe reduc-tion of soft-tissue chin thickness.

D I S C L O S U R E O F I N T E R E S T S

The authors certify that they have no affiliations with or involvement in any organization or entity with any financial interest (such as hono-raria; educational grants; participation in speakers' bureaus; member-ship, employment, consultancies, stock ownermember-ship, or other equity interest; and expert testimony or patent-licensing arrangements), or nonfinancial interest (such as personal or professional relationships,

affiliations, knowledge, or beliefs) in the subject matter or materials discussed in this article.

O R C I D

Giorgio Giampaoli https://orcid.org/0000-0003-0605-8126

Irene Dell'Acqua https://orcid.org/0000-0002-3812-4194

Ines Verner https://orcid.org/0000-0001-9824-8343

Dario Bertossi1 Giorgio Giampaoli1 Irene Dell'Acqua1 Ines Verner2 Ali Pirayesh3 Riccardo Nocini4 Pier F. Nocini1 1Department of Oral and Maxillofacial Surgery, University of Verona,

Verona, Italy

2Verner Clinic, Tel Aviv, Israel 3

Plastic Surgeon in Private Practice, Amsterdam, The Netherlands

4Section of ENT, Department of Surgical Sciences, Dentistry, Gynecology

and Pediatrics, University of Verona, Verona, Italy

Correspondence Dario Bertossi, MD, Department of Oral and Maxillofacial Surgery, University of Verona, Policlinico G.B. Rossi, Piazzale L. Scuro, 10, 37134 Verona, Italy. Email: dario.bertossi@univr.it

R E F E R E N C E S

Arnett, W., & Gunson, M. J. (1993). Facial analysis the key to successful dental treatment planning. American Journal of Orthodontics and Dentofacial Orthopedics, 103(4), 299–312.

Bertossi, D., Galzignato, P. F., Albanese, M., Botti, C., Botti, G., & Nocini, P. F. (2015). Chin microgenia: A clinical comparative study. Aes-thetic Plastic Surgery, 39(5), 651–658.

F I G U R E 2 Before and after hyaluronic acid filler (left-side after, right-side before) lateral view

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Bertossi, D., Sbarbati, A., Cerini, R., Barillari, M., Favero, V., Picozzi, V., Nocini, P. (2013). Hyaluronic acid: in vitro and in vivo analysis, bio-chemical properties and histological and morphological evaluation of injected filler. European Journal of Dermatology, 23(4), 449–455. DeLorenzi, C. (2017). New high dose pulsed hyaluronidase protocol for hyaluronic

acid filler vascular adverse events. Aesthetic Surgery Journal., 1(7), 37. Fang, M., Rahman, E., & Kapoor, K. M. (2018). Managing complications of

submental artery involvement after hyaluronic acid filler injection in chin region. Plastic and Reconstructive Surgery Global Open, 6(5), e1789. Guyuron, B., & Raszewski, R. L. (1990). A critical comparison of osteoplastic and alloplastic augmentation genioplasty. Aesthetic Plastic Surgery, 14, 199–206.

Richard, O., Ferrara, J. J., Cheynet, F., Guyot, L., Thiery, G., & Blanc, J. L. (2001). Complications of genioplasty. Revue de Stomatologie et de Chirurgie Maxillo-Faciale, 102, 34–39.

Trauner, R., & Obwegeser, H. (1957). The surgical correction of mandibular prognathism and retrognathia with consideration of genioplasty. I. Surgical procedures to correct mandibular prognathism and res-haping of the chin. Oral Surgery, Oral Medicine, and Oral Pathology, 10, 677–689.

White, J. B., & Dufresne, C. R. (2011). Management and avoidance of complications in chin augmentation. Aesthetic Surgery Journal, 31, 634–642.

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