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Video Laparoscopic Cholecystectomy : the last diagnostic step or the first Surgical procedure to prevent Cancer? A review of incidental Galbladder Cancer

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Copia di 462 - Video Laparoscopic Cholecystectomy. The last diagnostic step or the first surgical procedure to prevent cancer. A Review of incidental gallbladder cancer. - 2016

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Journal of Surgery

LAVIN TUNLIMIS

Research Article

Werra CD, et al. J Surg 2016.J116. DOI: 10.20011/SUR-116,000016

Video Laparoscopic Cholecystectomy

:

The Last

Diagnostic Step

or

the

First

Surgical

Procedure

to

Prevent Cancer? A

Review

of

Inci

dental

Gallbladder

Cancer

Carlo de Werra", Vincenzo Nicastro, Roberto Del Giudice, Gabriele

di Filippo, Rosa Di Micco, Francesco Mangani, Roberto

Tramontano

Department of Clinical Medicine and Surgery, Azienda Ospedaliera University, "Federico II" of Naples

"Corresponding author: Carlo de Werra, Department of Medicine Clinical and

Surgery, Azienda Ospedaliera University "Federico II" via S. Pansini 5-80131, Napoli. Tel: +081 74628​17; Fax: +0817462817; E-mail: dewerra@unina.it Citation: de Werra C,

Nicastro V, Giudice RD, Filippo GD, Micco RD, etal. (2016) Video Laparoscopic

Cholecystectomy: The Last Diagnostic Step or the First Surgical Procedure to Prevent Cancer? A Review of Incidental Gallbladder Cancer. J Surg 2016. JSUR-116. DOI:

10.29011/JSUR-116.000016 Received Date: 29 December, 2016; Accepted Date: 19 January, 2017; Published Date: 27 January, 2017

Abstract

Aim: Incidental gallbladder cancer (GBC) is a more and more frequent medical entity discovered on the specimen after

cholecystectomy. The aim of our study is to value the importance of cholecystectomy as last diagnostic step or surgical procedure to prevent invasive gallbladder cancer.

Histologicalroutinary examination of surgical specimen could discover a lot of hidden

gallbladder cancer. Material and methods: We collected data on patients treated with video

laparoscopic cholecystectomy (VLC) for lithia sis, from January 2000 to December 2015. We selected 477 patients, who underwent VLC after a preoperative gallstones positive US, and who had histologic analysis of gallbladder specimens. Our outcomes were retrospectively analyzed and compared to international results for a global review. Results: VLC has been realized in all patients with a rate of conversion of 5%. In 4 of these patients (0.9%) was

inciden tally discovered a GBC during pathological exam of specimens. All the samples

6 5 4 3 2 1 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 706 Research Article

Department of Clinical Medici… of sin gone VLC has increase… went VLC for cholelithiasis in … orexia or jaundice; only 15% (… car site. It was surgically exci… to begin therapy with 5-Ouoro… No Alterations Hyperplasia M… 129

hyperplasia 3cm

tine was then estimated arou… 1. Fuks D. Regimbeau JM, Le … 9. Ricardo AE, Feig BW, Ellis L… cer. Am J Gastroenterol 97: 2… 16. Choi SB, Han HJ, Kim CY, … 17. de Werra C, Di Micco R, Al… 36. Eringer (2000) Gallstones… 18. De Werra C. Bracciano L, … Earlygallbladdercarcinoma do… (2001) Radicalresectionimpro… 37. Kaechele V. Wabitsch M. … 40. Nagaraja V and Eslick GD … 41. Kaechele V. Wabitsch M. … 25. Roa I, Ibacache G, Roa J, … 44. Dihel AK and Beral V (198… 28. Carlo de Werra, S Condurr… tectomy. Eur J Surg Suppl 58… Ann Surg 93: 317-322.

58. D'Angelica M. Dalal KM, D… 51. Kresl JJ, Schild SE, Henni… • 52. De Werra C, Schiavone D… 53. Tugnoli G., Giorgini E., Bis… 55. de Werra Carlo Sergio Alo…

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