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A time-series analysis of temperature-related mortality in South Africa between 1997 and 2012

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 (http://ehp.niehs.nih.gov/)

 (http://iseepi.org/)

2016 CONFRNC

A time-series analysis of temperature-related mortality in South Africa

between 1997 and 2012

Introduction: There i an extenive literature reporting etimate of temperature-related mortalit in developed countrie, ut far fewer in the developing world, particularl in Africa. Furthermore, thee tudie report reult for onl one or a few citie and over relativel hort time period. Method: We conducted a time-erie anali of the temperature-mortalit relationhip in outh Africa uing a national dataet covering all 8.5 million death that occurred in 1997-2013. Relationhip were etimated with a ditriuted lag non-linear model with 21 da of lag, and pooled in a multivariate meta-anali. Relative rik (RR) were then calculated for cold and heat (at 99th and 1t percentile) uing the 75th percentile a the reference.  Reult: Preliminar aement of nine uran ditrict did not  nd a clear aociation etween heat and all-caue mortalit, with a flat relationhip eond the reference and a pooled RR of 0.98 (95%CI: 0.92-1.04). Cold e ect were evident ut modet if compared to other countr-level anale, with a pooled RR of 1.19 (1.11-1.28). Reult were imilar acro ditrict, with limited heterogeneit. Future anale will expand to include all remaining ditrict, compare e ect over time and pace and evaluate e ect modi cation  individual and area-level characteritic..

Concluion: A preliminar aement of the larget ever dataet for analzing temperature-mortalit aociation in (outh) Africa indicate all-caue mortalit urden aociated with cold ut not heat. In addition to it rarel explored geographic region, the dataet allow for invetigation of a numer of unique factor not poile in mot previou tudie, including the impact of a rapidl developing econom, a oung population tructure and a high prevalence of HIV. (http://www.ieepi.org/) Atract Numer: O-244 | ID: 3477 Noah covronick*, Princeton Univerit, United tate, Noah.covronick@princeton.edu; Fiorella Acquaotta, Univerit of Turin, Ital and London chool of Hgiene and Tropical Medicine, United Kingdom,  orella.acquaotta@unito.it; Franceco era, London chool of Hgiene and Tropical Medicine, United Kingdom, Franceco.era@lhtm.ac.uk; Diego Garzena, Univerit of Turin, Ital, diego.garzena@unito.it; Antonio Gaparrini, London chool of Hgiene and Tropical Medicine, United Kingdom, Antonio.Gaparrini@lhtm.ac.uk;

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