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Genetic background dictates pro-angiogenic factor production in preclinical models of colorectal cancer

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Figura

Figure  1.  Sequential  genetic  and  epigenetic  mutations  acquired  during  neoplastic  transformation  from  normal  intestinal  epithelium  to  colorectal  carcinoma [5]
Figure 2. Signaling of chemokines in TSI [26].
Figure 3. Principal signaling pathways activated by IL-8-CXCR1/2 binding, to  regulate cell survival, proliferation, angiogenesis and metastasis [28]
Figure 3. PTEN expression in 29 CRC cancer cell lines. A. Cells were lysed  and analyzed by Western Blotting using antibodies specific for PTEN
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