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Macrolide prescriptions and erythromycin resistance of streptococcus pyogenes

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Gagliotti C, Nobilio L, Milandri M, Moro ML; Emilia-Romagna Antibiotic Resistance Study Group Macrolide prescriptions and erythromycin resistance of Streptococcus pyogenes Clin Infect Dis. 2006 Apr 15; 42 (8): 1153-6. Epub 2006 Mar 6.

This study shows a significant association between the number of macrolide prescriptions reimbursed by the Italian National Health Service and resistance of Streptococcus pyogenes to erythromycin in children from a region in northern Italy with high prevalence of erythromycin resistance. Recent prescription of a macrolide (especially azithromycin) is a predictor of erythromycin resistance, as well as a possible risk factor for resistance at a community level. Publication Types: Multicenter Study

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