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Mutant p53 inhibits microRNA biogenesis by interfering with the Microprocessor complex

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Academic year: 2021

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Figura

Figure 1. A  schematic  representation  depicting  the  canonical  miRNA  biogenesis  pathway  and  the  general  mechanisms  whereby  normal  miRNA  expression  and  function  can  be  deregulated  in  cancer  (ref
Figure  2.  Post-transcriptional  regulation  of  miRNA  biogenesis  in  response  to  cellular  signals
Figure 3. Contribution of miRNAs to cancer pathways (ref. 5).
Figure 4. Widespread downregulation of miRNA by mutp53.
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