• Non ci sono risultati.

Metabolism of methylamine by semicarbazide-sensitive amine oxidase in white and brown adipose tissue of the rat.

N/A
N/A
Info
Scarica
Protected

Academic year: 2021

Condividi "Metabolism of methylamine by semicarbazide-sensitive amine oxidase in white and brown adipose tissue of the rat."

Copied!
1
0
0

Caricamento.... (Visualizza il testo completo ora)

Scarica adesso ( 1 pagine )

Testo completo

(1)

Biochem Pharmacol. 1993 Aug 17;46(4):603-7.

Metabolism of methylamine by semicarbazide-sensitive amine oxidase in white and brown adipose tissue of the rat.

Conforti L1, Raimondi L, Lyles GA.

Author information

Abstract

The metabolism of [14C]methylamine (MA) by amine oxidase activity in rat white and brown adipose tissue homogenates, and in mature adipocytes from these tissues has been studied. Oxidation of MA was

completely inhibited by 0.1-1 mM semicarbazide, without being affected by the monoamine oxidase (MAO) inhibitor, pargyline (1 mM), indicating that MA is metabolized by semicarbazide-sensitive amine oxidase (SSAO) and not by MAO. The mean Km for MA deamination in all of these sources was around 250-300 microM. SSAO activity towards MA was also demonstrated in white and brown pre-adipocytes,

transformed to the adipose phenotype by treatment in culture for 7 days with lipogenic agents. These results are similar to previous findings that SSAO in vascular smooth muscle is able to metabolize aliphatic amines such as MA, and furthermore suggest that SSAO may play a role in adipose tissue function and/or maturation.

PMID:

Riferimenti

Scarica adesso ( PDF - 1 pagine - 332.10 KB )

Documenti correlati

Well- differentiated cancer cells are similar to those in the tissue of origin and are essentially benign

Platelet-derived growth factor receptor Colony-stimulating factor-1 receptor Steel

1.3 The evolution of the white adipose tissue concept

Adipose tissue macrophages (ATM) in these obese models was not however reduced to that of the lean mice, thus suggesting that other factors induced by obesity concur to the active

Prove that there is somec ∈ (0, 1) such that f(4)(c

[r]

Prove that there are constantsc and c′ such that c ≤ f (n)/ log n ≤ c′ for sufficiently largen (that is,f (n

[r]

So it is necessary to select groups of organisms that can give adequate information and sampling methods that are reliable, rapid and economical.

Non parametric analysis (Multidimensional Scaling and Cluster Analysis) and statistical test (Kruskal-Wallis test) allow us to affirm that the peculiar environmental

Our results also suggest that i) maturation is not hampered by FIV infection

Feline AIDS is caused by feline immunodeficiency virus (FIV) and it is considereds a model for the human illness because the two diseases have many features in common. Little is

Il patrimonio culturale come fonte di ricchezza e conoscenza. Analisi e proposte di sviluppo turistico del territorio a sud della provincia di Treviso.

I musei della città di Treviso, anche se non presenti all’interno del territorio considerato, possono farne parte, in quanto porzione del sistema

These properties of the composites are very sensitive to small changes in the amount of metal and in the size and shape of the nanoparticles

The aim of this thesis work was to modify one of most versatile way to obtain nanoparticle imbedded into polymer matrices in order to better control the physical properties