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BIBLIOGRAFIA Abelmann WH. (1984) Classification and natural history of primary myocardial disease.

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BIBLIOGRAFIA

Abelmann WH. (1984) Classification and natural history of primary myocardial disease. Prog Cardiovasc Dis.4;27:73–94.

Arbustini E, Diegoli M, Fasani R et al. (1998) Mitochondrial DNA mutations and mitochondrial abnormalities in dilated cardiomyopathy. Am J Pathol; 153: 1501–10.

Avogaro A, Nosadini R, Doria A, Fioretto P, Velussi M, Vigorito C, Sacca L, Toffolo G, Cobelli C, and Trevisan R. (1990) Myocardial metabolism in insulin-deficient diabetic humans without coronary artery disease. Am J Physiol Endocrinol Metab 258: E606–E618, . Baba A, Yoshikawa L Ogawa S (2002)Autoantibodies produced against sarcolemmal NaK ATPase. Possible upstream targets of arrytmias and sudden death in patiets with dilated cardiomyopathy J Am Coll CaRdiol 40: 1153, .

Bagger, J. P., Thomassen, A., & Nielsen, T. T. (2000). Cardiac energy metabolism in patients with chest pain and normal coronary angiograms. Am J Cardiol 85, 315-320.

Bardenheuer, H., & Schrader, J. (1986). Supply-demand ratio for oxygen determines formation of adenosine by heart. Am J Physiol 250 (2 Pt 2), H173–H180.

Bauersachs, J., Popp, R., Hecker, M., Sauer, E., Fleming, I., & Busse, R. (1996). Nitric oxide attenuates the release of endothelium-derived hyperpolarizing factor. Circulation 94, 3341–3347.

Baumgart, D., Haude, M., Görge, G., Liu, F., Ge, J., Große-Eggebrecht, C., Erbel, R., & Heusch, G. (1999). Augmented a adrenergic constriction of atherosclerotic human coronary arteries. Circulation 99, 2090–2097.

(2)

Bayliss, W. M. (1902). On the local reactions of the arterial wall to changes of internal pressure. J Physiol (Lond) 28, 220–230.

Belardinelli R Porcaro A. (2001) Effects of Trimetazidine on contractile response of chronically disfunctional myocardium to low dose dobutamine in ischaemic cardiomyopathy. Eur Heart J ;22:2164-2170.

Berne, R. M. (1980). The role of adenosine in the regulation of coronary blood flow. Circ Res 47, 807–813.

Bernstein, R. D., Ochoa, F. Y., Xu, X., Forfia, P., Shen, W., Thompson, C. I., & Hintze, T. H. (1996). Function and production of nitric oxide in the coronary circulation of the conscious dog during exercise. Circ Res 79, 840–848.

Bing RJ, Siegel A, Vitale A, Taeschler M, Balboni FSE, Klappe M, and Edwards S. (1953) Metabolic studies on the human heart in vivo. I. Studies on carbohydrate metabolism of the human heart. Am J Med 15: 284–296.

Bing RJ. The metabolism of the heart. Harvey Lect. 1955;50:27–70. 76.

Braunwald E, Bristow MR. Congestive heart failure. Fifty years of progress. Circulation 102: IV, 14, 2000.

Broderick TL, Quinney HA, Barker CC, Lopaschuk GD.(1993) Beneficial effects of carnitine on mechanical recovery of rat hearts reperfused after a transient period of global ischemia is accompanied by a stimulation of glucose oxidation. Circulation ;87:972–981. Bucala, R., Tracey, K. J., & Cerami, A. (1991). Advanced glycosylation products quench nitric oxide and mediate defective endothelium-dependent vasodilatation in experimental diabetes. J Clin Invest 87, 432–438.

Buchwald A et al. (1990) (Alterations in the mitochondrial respiratory chain in human dilated cardiomyopathy. Eur Heart J :11:509-16.

(3)

Buffon A, Rigattieri S, Santini SA, Ramazzotti V, Crea F, Giardina B, Maseri A. (2000) Myocardial ischemia-reperfusion damage after pacing-induced tachycardia in patients with cardiac syndrome X. Am J Physiol ;279:H2627-33.

Buttrick PM et al. (1994) Alterations in gene expression in the rat heart after chronic pathological and physiological loads. J Mol Cell Cardiol. 26:61-7.

Camici, P., Marraccini, P., Marzilli, M., Lorenzoni, R., Buzzigoli, G., Puntoni, R., Boni, C., Bellina, C. R., Klassen, G. A., L'Abbate, A., & . (1989). Coronary hemodynamics and myocardial metabolism during and after pacing stress in normal humans. Am J Physiol 257, E309-E317.

Camici, P. G., Marraccini, P., Lorenzoni, R., Buzzigoli, G., Pecori, N., Perissinotto, A., Ferrannini, E., L'Abbate, A., & Marzilli, M. (1991). Coronary hemodynamics and myocardial metabolism in patients with syndrome X: response to pacing stress. J Am Coll Cardiol 17, 1461-1470.

Cannan, C. R., Burnett, J. C., Brandt, R. R., & Lerman, A. (1995). Endothelin at pathophysiological concentrations mediates coronary vasoconstriction via the endothelin-A receptor. Circulation 92, 3312–3317.

Cartegni L, di Barletta MR, Barresi R et al. (1997)Heart-specific localization of emerin: new insights into Emery-Dreifuss muscular dystrophy. Hum Mol Genet ; 6: 2257–64.

Cecchi F, Gistri R, Olivotto I, Lorenzoni R, Chiriatti G, Camici PG: Impaired coronary microvascular function as an independent prognostic predictor in patients with hypertrophic cardiomyopathy. New Engl J Med 2003;349:1027-35.

Celermajer DS, Sorensen KE, Georgakopoulos D, et al. (1993) Cigarette smoking is associated with dose-related and potentially reversible impairment of endothelium-dependent dilation in healthy young adults. Circulation ;88:2149-55.

Cerqueira MD, Weissman NJ, Dilsizian V, Jacobs AK, Kaul S, Laskey WK, Pennell DJ, Rumberger JA, Ryan T, Verani MS. (2002) Standardized myocardial segmentation and

(4)

nomenclature for tomographic imaging of the heart. A Statement for Healthcare Professionals from the Cardiac Imaging Committee of the Council on Clinical Cardiology of the American Heart Association. Circulation ;105:539–542.

Chareonthaitawee P, Kaufmann PA, Rimoldi O, Camici PG.(2001) Heterogeneity of resting and hyperemic myocardial blood flow in healthy humans. Cardiovasc Res. ;50:151– 161.

Chauhan A, Mullins PA, Taylor G, Petch MC, Schofield PM. (1997)Both endothelium-dependent and endothelium-inendothelium-dependent function is impaired in patients with angina pectoris and normal coronary angiograms. Eur Heart J ;18:60-8.

Chen V, Wagner G, and Spitzer JJ.(1984) Regulation of substrate oxidation in isolated myocardial cells by beta-hydroxybutyrate. Horm Metab Res 16: 243–247.

Cheng L, Ding G et al. (2004) Cardiomyocite- restricted peroxisome proliferator- activated receptor delta deletion perturbs myocardial fatty acid oxidation and leads to cardiomyopathy.

Nature ;10:1245-52.

Cherry, P., Furchgott, R. F., Zawadzki, J. V., & Jothianandan, D. (1982). Role of endothelial cells in relaxation of isolated arteries by bradykinin. Proc Natl Acad Sci USA 79, 2106–2110.

Chien KR(2003) Genotype, phenotype. Upstairs, doenstairs in the family of cardiomyopathies. J Clin Invest 111: 175.

Chilian, W. M., Eastham, C. L., & Marcus, M. L. (1986). Microvascular distribution of coronary vascular resistance in beating left ventricle. Am J Physiol 251 (4 Pt 2), H779–H788. Chilian, W. M. (1991b). Functional distribution of alpha 1- and alpha 2-adrenergic receptors in the coronary microcirculation. Circulation 84, 2108–2122.

(5)

Chilian, W. M., Dellsperger, K. C., Layne, S. M., Eastham, C. L., Armstrong, M. A., Marcus, M. L., & Heistad, D. D. (1990). Effects of atherosclerosis on the coronary microcirculation. Am J Physiol 258 (2 Pt 2), H529–H539.

Choudhury L, Rosen SD, Patel D, Nihoyannopoulos, Camici PG.(1997) Coronary vasodilator reserve in primary and secondary left ventricular hypertrophy. Eur Heart J 1997;18:108-16.

Clarke, J. G., Davies, G. J., Kerwin, R., Hackett, D., Larkin, S., Dawbarn, D., Lee, Y., Bloom, S. R., Yacoub, M., & Maseri, A. (1987). Coronary artery infusion of neuropeptide Y in patients with angina pectoris. Lancet 1, 1057–1059.

Coupe, M. O., Mak, J. C. W., Yacoub, M., Oldershaw, P. J., & Barnes, P. J. (1990). Autoradiographic mapping of calcitonin gene-related peptide receptors in human and guinea pig hearts. Circulation 81, 741–747.

Crabos, M., Coste, P., Paccalin, M., Tariosse, L., Daret, D., Besse, P., & Bonoron-Adèle, S. (1997). Reduced basal NO-mediated dilation and decreased endothelial NO-synthase expression in coronary vessels of spontaneously hypertensive rats. J Mol Cell Cardiol 29, 55– 65.

Crea F, Gaspardone A. (1995) Angina pectoris. New look to an old symptom. Circulation 112: 756.

D’Adamo P, Fassone L, Gedeon A et al. (1997) The X-linked gene G4·5 is responsible for different infantile dilated cardiomyopathies. Am J Hum Genet 61: 862–7.

Davis, M. J., Donovitz, J. A., & Hood, J. D. (1992). Stretch-activated single-channel and whole-cell currents in vascular smooth muscles. Am J Physiol 262 (4 Pt 1), C1083–C1088. Davis, M. J., & Hill, M. A. (1999). Signaling mechanisms underlying the vascular myogenic response. Physiol Rev 79, 387–423.

(6)

Davies, P. F. (1995). Flow-mediated endothelial mechanotransduction. Physiol Rev 75, 519– 560.

Davila-Roman VG, Vedala G et al. (2002) Altered myocardial fatty acid and glucose metabolism in idiopathic dilated cardiomyopathy J Am Coll Cardiol ;40: 271-7.

Dec et al ,(1994) Pathological findings in Dilated Cardiomyopathy. Br Heart J 221; 354.1984 Deedwania PC (2003) The key to unravelling the mistery of mortality in heart failure. An integrative approach. Circulation 107:1719.

DeWitt, D. F., Wangler, R. D., Thompson, C. I., & Sparks, H. V., Jr. (1983). Phasic release of adenosine during steady state metabolic stimulation in the isolated guinea pig hearts. Circ Res 53, 636–643.

Depre C Gaussin V (1998)et al Inhibition of myocardial glucose uptake by cGMP. Am J Physiol Heart Circ Physiol, ; 274:1443-8.

Depre C, Rider MH, and Hue L. (1998)Mechanisms of control of heart glycolysis. Eur J Biochem 258: 277–290.

Di Carli MF, Janisse J, Grunberger G, Ager J. (2003) Role of chronic hyperglycemia in the pathogenesis of coronary microvascular dysfunction in diabetes. J Am Coll Cardiol ;41:1387-93.

Drexler, H., Zeiher, A. M., Wollschläger, H., Meinertz, T., Just, H., & Bonzel, T. (1989). Flow-dependent coronary artery dilatation in humans. Circulation 80, 466–474.

Dries DL, Exner DV, Gersh BJ, et al. 1999 Racial differences in the outcome of ventricular dysfunction. N Engl J Med 340:609..

Duan J, Mc Fadden GE, Borgerding AJ et al, 2002.Overexpression of alcohol deydrogenase exacerbates ethanol-induced contractile defects in cardiac myocites. Am J Physiol 282: H1216,

(7)

Duncker, D. J., van Zon, N. S., Pavek, T. J., Herrlinger, S. K., & Bache, R.J. (1995). Endogenous adenosine mediates coronary vasodilation during exercise after K1 ATP channel blockade. J Clin Invest 95, 285–295.

Durante, W., Sunahara, F. A., & Sen, A. K. (1989). Effect of diabetes on metabolic coronary dilatation in the rat. Cardiovasc Res 23, 40–45.

Edwards WD, Tajik AJ, Seward JB. (1981)Standardized nomenclature and anatomic basis for regional tomographic analysis of the heart. Mayo Clin Proc. ;56:479–497.

Embrey, R. P., Brooks, L. A., & Dellsperger, K. C. (1997). Mechanism of coronary microvascular responses to metabolic stimulation. Cardiovasc Res 35, 148–157.

Factor, S. M., Okun, E. M., & Minase, T. (1980). Capillary microaneurysms in the human diabetic heart. N Engl J Med 302, 384–388.

Fell DA.(1998) Increasing the flux in metabolic pathways: a metabolic control analysis perspective. Biotechnol Bioeng 58: 121–124,.

Feigl, E. O. (1983). Coronary physiology. Physiol Rev 63, 1–205.

Fernadez-Sola J, Nicolas JM, Oriola J et al, (2002). Angiotensin-converting enzyme gene polimorphysm is associated with vulnerability in alcoholic cardiomyopathy Ann Intern Med 137: 221. 2002

Gauthier-Rein, K. M., & Rusch, N. J. (1998). Distinct endothelial impairment in coronary microvessels from hypertensive Dahl rats. Hypertension 31, 328–334.

Gertz EW, Wisneski JA, Stanley WC, and Neese RA.(1988) Myocardial substrate utilization during exercise in humans: dual carbon-labeled carbohydrate isotope experiments. J Clin Invest 82: 2017–2025, .

(8)

Gibson CM, Cannon CP, Murphy SA, Ryan KA, Mesley R, Marble SJ, McCabe CH, Van De Werf F, Braunwald E. (2000) Relationship of TIMI myocardial perfusion grade to mortality after administration of thrombolytic drugs. Circulation;101:125-30

Gilligan, D. M., Guetta, V., Panza, J. A., García, C. E., Quyyumi, A. A., & Cannon, R. O., III. (1994). Selective loss of microvascular endothelial function in human hypercholesterolemia. Circulation 90, 35–41.

Gimelli A, Schneider-Eicke J, Neglia D,(1998) et al. Homogeneously reduced versus regionally impaired myocardial blood flow in hypertensive patients: two different patterns of myocardial perfusion associated with degree of hypertrophy. J Am Coll Cardiol;31:366-373.

Golino, P., Piscione, F., Willerson, J. T., Cappelli-Bigazzi, M., Focaccio, A., Villari, B., Indolfi, C., Russolillo, E., Condorelli, M., & Chiariello, M. (1991). Divergent effects of serotonin on coronary-artery dimensions and blood flow in patients with coronary atherosclerosis and control patients. N Engl J Med 324, 641–648.

Gregorini L, Jean Marco J, Kozakova M (1998) et al. a-Adrenergic blockade improves recovery of myocardial perfusion and function after coronary stenting in patients with acute myocardial infarction. Circulation.;99:482-90

Groves, P., Kurz, S., Just, H., & Drexler, H. (1995). Role of endogenous bradykinin in human coronary vasomotor control. Circulation 92, 3424–3430.

Haghighi K, Kolokathis F, Pater L (2003)Human phospholamban null results in lethal dilated cardiomyopathy revealing a critical difference between mouse and human. J Clin Invest 111: 869.

Halushka, P. V., Mais, D. E., Mayeux, P. R., & Morinelli, T. A. (1989). Thromboxane, prostaglandin and leukotriene receptors. Annu Rev Pharmacol Toxicol 29, 213–239.

(9)

Heyndrickx, G. R., Boettcher, D. H., & Vatner, S. F. (1976). Effects of angiotensin, vasopressin, and methoxamine on cardiac function and blood flow distribution in conscious dogs. Am J Physiol 231 (5 Pt 1), 1579–1587.

Higgins AJ, Morville M, et al. (1980) Oxfenicine diverts rat muscle metabolism from fatty acids to carbohydrate oxidation and protects the ischaemic rat heart. Life Sci 27:963-970. Hintze, T. H., & Vatner, S. F. (1984). Reactive dilation of large coronary arteries in conscious dogs. Circ Res 54, 50–57.

Hozumi T, Yoshida K, Ogata Y, et al(1998) Noninvasive assessment of significant left anterior descending coronary artery stenosis by coronary flow velocity reserve with transthoracic color Doppler echocardiography. Circulation;97:1557–1562.

Huang, A., Sun, D., Kaley, G., & Koller, A. (1998). Superoxide released to high intra-arteriolar pressure reduces nitric oxide-mediated shear stress- and agonist-induced dilations. Circ Res 83, 960–965.

Hupf, H., Grimm, D., Riegger, G. A. H., & Schunkert, H. (1999). Evidence for a vasopressin system in the rat heart. Circ Res 84, 365–370.

Ingwall JS. ATP and the heart. Boston, MA: Kluwer, 2001.

Inoue T, Sakai Y, Morooka S, Hayashi T, Takayanagi K, Yamanaka T, Kakoi H, Takabatake Y(1993). Coronary flow reserve in patients with dilated cardiomypathy. Am Heart J.125:93-98.

Ito H, Maruyama A, Iwakura K et al. (1996) Clinical implications of the “No-Reflow” phenomenon. A predictor of complications and left ventricular remodeling in reperfused anterior wall myocardial infarction. Circulation;93:223-8.

Itoh-Satoh M, Hayashi Y, Nishi U. (2002)Titin mutation as the molecular basis of Dilated cardiomyopathy biochem Biophysiol Res Commun 291:385..

(10)

Jerosch-Herold M, Wilke N, Stillman AE (1998). Magnetic resonance quantification of the myocardial perfusion reserve with a Fermi function model for constrained deconvolution. Med Phys. Jan ;25(1):73-84.

Jones, C. J. H., Kuo, L., Davis, M. J., & Chilian, W. M. (1995b). Regulation of coronary blood flow: coordination of heterogeneous control mechanisms in vascular microdomains. Cardiovasc Res 29, 585–596

Jones, C. J. H., Kuo, L., Davis, M. J., DeFily, D. V., & Chilian, W. M. (1995c). Role of nitric oxide in the coronary microvascular responses to adenosine and increased metabolic demand. Circulation 91, 1807–1813.

Kaijser L and Berglund B. (1992) Myocardial lactate extraction and release at rest and during heavy exercise in healthy men. Acta Physiol Scand 144: 39–45.

Kanatsuka, H., Lamping, K. G., Eastham, C. L., Dellsperger, K. C., & Marcus, M. L. (1989). Comparison of the effects of increased myocardial oxygen consumption and adenosine on the coronary microvascular resistance. Circ Res 65, 1296–1305.

Kanatsuka, H., Lamping, K. G., Eastham, C. L., Marcus, M. L., & Dellsperger, K. C. (1991). Coronary microvascular resistance in hypertensive cats. Circ Res 68, 726–733.

Kantor PR, Robertson MA Lopaschuk GD. (1999) Volume overload hypertrophy of the newborn heart slows the maturation of enzymes involved in the regulation of fatty acids metabolism. J Am Coll Cardiol 33: 1724-34.

Katsuda, Y., Egashira, K., Ueno, H., Akatsuka, Y., Narishige, T., Arai, Y., Takayanagi, T., Shimokawa, H., & Takeshita, A. (1995). Glibenclamide, a selective inhibitor of ATP-sensitive K1 channels, attenuates metabolic coronary vasodilatation induced by pacing tachycardia in dogs. Circulation 92, 511–517.

Kaufmann PA and Camici PG. (2005) Myocardial blood flow by PET and its implications for clinical use. J Nucl Med ; 46: 75-88.

(11)

Kaufmann PA, Gnecchi-Ruscone T, di Terlizzi M, Schäfers KP, Lüscher TF, Camici PG. (2000) Coronary heart disease in smokers: vitamin C restores coronary microcirculatory function. Circulation.;102:1233-8.

Kerbey AL, Randle PJ, Cooper RH, Whitehouse S, Pask HT, and Denton RM (1976). Regulation of pyruvate dehydrogenase in rat heart. Mechanism of regulation of proportions of dephosphorylated and phosphorylated enzyme by oxidation of fatty acids and ketone bodies and of effects of diabetes: role of coenzyme A, acetylcoenzyme A and reduced and oxidized nicotinamide-adenine dinucleotide. Biochem J 154: 327–348.

Kersten, J. R., Brooks, L. A., & Dellsperger, K. C. (1995). Impaired microvascular response to graded coronary occlusion in diabetic and hyperglycemic

dogs. Am J Physiol 268 (4 Pt 2), H1667–H1674.

Komaru, T., Lamping, K. G., Eastham, C. L., Harrison, D. G., Marcus, M. L., & Dellsperger, K. C. (1991b). Effect of an arginine analogue on acetylcholine-induced coronary microvascular dilatation in dogs. Am J Physiol 261 (6 Pt 2), H2001–H2007.

Komaru, T., Tanikawa, T., Sugimura, A., Kumagai, T., Sato, K., Kanatsuka, H., & Shirato, K. (1997). Mechanisms of coronary microvascular dilation induced by the activation of pertussis toxin-sensitive G proteins are vessel-size dependent. Heterogeneous involvement of nitric oxide pathway and ATP-sensitive K1 channels. Circ Res 80, 1–10.

Kotzerke J, Glatting G, van den Hoff J, et al. (2001) Validation of myocardial blood flow estimation with nitrogen-13 ammonia PET by the argon inert gas technique in humans. Eur J Nucl Med.;28:340 –345.

Kuo, L., Davis, M. J., & Chilian, W. M. (1995). Longitudinal gradients for endothelium-dependent and-inendothelium-dependent vascular responses in the coronary microcirculation. Circulation 92, 518–525.

Kuo, L., Davis, M. J., Cannon, M. S., & Chilian, W. M. (1992). Pathophysiological consequences of atherosclerosis extend into the coronary microcirculation. Restoration of endothelium-dependent responses by L-arginine. Circ Res 70, 465–476.

(12)

Kuo, L., Davis, M. J., & Chilian, W. M. (1988). Myogenic activity in isolated subepicardial and subendocardial coronary arterioles. Am J Physiol 255 (6 Pt 2), H1558–H1562.

Kuo, L., Chilian, W. M., & Davis, M. J. (1990a). Coronary arteriolar myogenic response is independent of endothelium. Circ Res 66, 860–866.

Kuo, L., Davis, M. J., & Chilian, W. M. (1990b). Endothelium-dependent, flow-induced dilation of isolated coronary arterioles. Am J Physiol 259 (4 Pt 2), H1063–H1070.

Kuo, L., Arko, F., Chilian, W. M., & Davis, M. J. (1993). Coronary venular responses to flow and pressure. Circ Res 72, 607–615.

Lamping, K. G., Kanatsuka, H., Eastham, C. L., Chilian, W. M., & Marcus, M. L. (1989). Nonuniform vasomotor responses of the coronary microcirculation to serotonin and vasopressin. Circ Res 65, 343–351.

Lamping, K. G., Bloom, E. N., & Harrison, D. G. (1994a). Regulation of native collateral vessel dilation after coronary occlusion in the dog. Am J Physiol 266 (2 Pt 2), H769–H778. Lamping, K. G., Chilian, W. M., Eastham, C. L., & Marcus, M. L. (1992a). Coronary microvascular response to exogenously administered and endogenously released acetylcholine. Microvasc Res 43, 294–307.

Langenstroer, P., & Pieper, G. M. (1992). Regulation of spontaneous EDRF release in diabetic rat aorta by oxygen free radicals. Am J Physiol 263 (1 Pt 2), H257–H265.

Lee, L., Campbell, R., Scheuermann-Freestone, M., Taylor, R., Gunaruwan, P., Williams, L., Ashrafian, H., Horowitz, J., Fraser, A. G., Clarke, K., & Frenneaux, M. (2005). Metabolic modulation with perhexiline in chronic heart failure: a randomized, controlled trial of short-term use of a novel treatment. Circulation 112, 3280-3288.

Lee, M. A., Böhm, M., Paul, M., & Ganten, D. (1993). Tissue renin-angiotensin systems. Their role in cardiovascular disease. Circulation 87 (5 suppl. IV), IV7–IV13.

(13)

Liao, J. C., & Kuo, L. (1997). Interaction between adenosine and flowinduced dilation in coronary microvascular network. Am J Physiol 272

Liao, J. K., & Clark, S. L. (1995). Regulation of G-protein ai2 subunit expression by oxidized low-density lipoprotein. J Clin Invest 95, 1457– 1463.

Limas CL, Limas CJ, Boudoulas H, et al.(1992) T-cell receptor gene polymorphisms in familial cardiomyopathy: correlation with anti-b-receptor autoantibodies. Am Heart J ;124:1258–63.

Lindner O, Vogt J et al. (2005) Global and regional myocardial oxygen consumption and blood flow in severe cardiomyopathy with bundle branch block. Eur J of Heart Fail;7 :225-230.

Lionetti V, Linke A et al. (2005) Carnitine palmitoyl transferase-1 inhibition prevents ventricular remodeling and delays decompensation in pacing induced heart failure. Cardiov Res; 66:274-281.

Liu T, Yiao M, Zhao I (2002) Relationship of myocardial remodelling to the genesis of serum antibodies to cardiac beta1 adrenoceptors and muscarinic type 2 acetilcoline receptors in rats J Am Coll Cardiol 39: 1866.

Liu B, Clanachan AS, Schulz R, Lopaschuk GD. (1996) Cardiac efficiency is improved following ischemia by altering both the source and fate of protons. Circ Res ;79:940 –948. Liu YH, Yang XP, Nass O, Sabbah HN, Peterson E, and Carretero OA. (1997) Chronic heart failure induced by coronary artery ligation in Lewis inbred rats. Am J Physiol Heart Circ Physiol 272: H722–H727.

Lopaschuk GD.(2002) Metabolic abnormalities in the diabetic heart. Hert Fail Review, 212; 456.

(14)

Lüscher, T. F., Boulanger, C. M., Dohi, Y., & Yang, Z. H. (1992). Endothelium- derived contracting factors. Hypertension 19, 117–130.

Ma, X. L., Lopez, B. L., Liu, G.-L., Christopher, T. A., Gao, F., Guo, Y., Feuerstein, G. Z., Ruffolo, R. R., Jr., Barone, F. C., & Yue, T. L. (1997). Hypercholesterolemia impairs a detoxification mechanism against peroxynitrite and renders the vascular tissue more susceptible to oxidative injury. Circ Res 80, 894–901.

Marcus, M. L., Chilian, W. M., Kanatsuka, H., Dellsperger, K. C., Eastham, C. L., & Lamping, K. G. (1990). Understanding the coronary circulation through studies at the microvascular level. Circulation 82, 1–7.

Marcus ML, Harrison DG, Chilian WM, et al. (1987) Alterations in the coronary circulation in hypertrophied ventricles. Circulation;75:19-25.

Maron BJ, Tobin JA, Thiene G et al (2006) ContemporaryDefinitions and Classification of the Cardiomyopathies. An American Heart Association Scientific Statement From the Council on Clinical Cardiology, Heart Failure and Transplantation Committee; Quality of Care and Outcomes Research and Functional Genomics and Translational Biology Interdisciplinary Working Groups; and Council on Epidemiology and Prevention. Circulation 1:13;125.

Marzilli M, Sambuceti G, Testa R, Silvio Fedele F.(2002) Platelet glycoprotein IIb/IIIa receptor blockade and coronary resistance in unstable angina. J Am Coll Cardiol ;40:2102–9. Maseri A, Crea F, Kaski JC, Crake T. (1991) Mechanisms of angina pectoris in Syndrome X. J Am Coll Cardiol ;17:499-506.

Matsunaga, T., Okumura, K., Ishizaka, H., Tsunoda, R., Tayama, S., Tabuchi, T., & Yasue, H. (1996). Impairment of coronary blood flow regulation by endothelium-derived nitric oxide in dogs with alloxan-induced diabetes. J Cardiovasc Pharmacol 28, 60–67.

Maturi, M. F., Martin, S. E., Markle, D., Maxwell, M., Burruss, C. R., Speir, E., Greene, R., Ro, Y. M., Vitale, D., Green, M. V., Goldstein, S. R., Bacharach, S. L., & Patterson, R. E.

(15)

(1991). Coronary vasoconstriction induced by vasopressin. Production of myocardial ischemia in dogs by constriction of nondiseased small vessels. Circulation 83, 2111–2121. McMurray, J. J., Ray, S. G., Abdullah, I., Dargie, H. J., & Morton, J. J. (1992). Plasma endothelin in chronic heart failure. Circulation 85, 1374–1379.

Mestroni L, Giacca M. (1997) Molecular genetics of dilated cardiomyopathy. Curr Opin Cardiol; 12: 303–9.

Miyauchi, T., Yanagisawa, M., Tomizawa, T., Sugishita, Y., Suzuki, N., Fujino, M., Ajisaka, R., Goto, K. & Masaki, T. (1989). Increased plasma concentrations of endothelin-1 and big endothelin-1 in acute myocardial infarction. Lancet 2, 53–54.

Mombouli, J.-V., & Vanhoutte, P. M. (1997). Endothelium-derived hyperpolarizing factor(s): updating the unknown. Trends Pharmacol Sci 18, 252–256.

Mootha VK, Arai AE, and Balaban RS. (1997) Maximum oxidative phosphorylation capacity of the mammalian heart. Am J Physiol Heart Circ Physiol 272: H769–H775.

Morgan HE, Henderson MJ, Regen DM, Park CR. (1961) Regulation of glucose uptake in muscle, I: the effects of insulin and anoxia on glucose transport and phosphorylation in the isolated perfused heart of normal rats. J Biol Chem.;236:253–261.

Mueller HS, Ayres ST. (1978) Metabolic responses of the heart in acute myocardial infarction in man. Am J Cardiol;42:363–371.

Myers, P. R., Banitt, P. F., Guerra, R., Jr., & Harrison, D. G. (1989). Characteristics of canine coronary resistance arteries: importance of endothelium. Am J Physiol 257 (2 Pt 2), H603–H610.

Myers, P. R., Katwa, L. C., Tanner, M., Morrow, C., Guarda, E., & Parker, J. L. (1994). Effects of angiotensin II on canine and porcine coronary epicardial and resistance arteries. J Vasc Res 31, 338–346.

(16)

Myers PR Muller JM & Tanner, M. A. (1991). Effects of oxygen tension on endothelium dependent responses in canine coronary microvessels. Cardiovasc Res 25, 885–894.

Nahser, P. J., Jr., Brown, R. E., Oskarsson, H., Winniford, M. D., & Rossen, J. D. (1995). Maximal coronary flow reserve and metabolic coronary vasodilation in patients with diabetes mellitus. Circulation 91, 635–640.

Nakashima, M., Mombouli, J.-V., Taylor, A. A., & Vanhoutte, P. M. (1993). Endothelium-dependent hyperpolarization caused by bradykinin in human coronary arteries. J Clin Invest 92, 2867–2871.

Nava, E., Noll, G., & Lüscher, T. F. (1995). Increased activity of constitutive nitric oxide synthase in cardiac endothelium in spontaneous hypertension. Circulation 91, 2310–2313. Neese RE, Gertz EW, Wisneski JA, Gruenke LD, and Craid LC. (1983) A stable isotope technique for investigating lactate metabolism in humans. Biomed Mass Spectrom 10: 458– 462.

Neglia D, Parodi O, Gallopin M, Sambuceti G, Giorgetti A, Pratali L, Salvadori P et al.(1995): Myocardial blood flow responce to pacing tachycardia and to dipyradamole infusion in patients with dilated cardiomyopathy without overt heart failure. Circulation, 92, 796–804.

Neglia D, Mezini C, Toschi E, et al. (2001) Regional myocardial flow metabolism relationship in patients with idiopathic dilated cardiomyopathy. J Am Coll Cardiol.;37:187A. Neglia D, Trivieri MG, Michelassi C, Gallopin M, Pratali L, Poddighe R, Salvadori P et al.(2002): Prognostic value of myocardial blood flow impairment in patients with idiopathic left ventricular dysfunction. Circulation, 105, 186–193.

Neubauer S, Horn M et al. (1997) Myocardial phosphocreatine-to-ATP-ratio is a predictor of mortality in patients with dilated cardiomyopathy. Circulation;96: 2190-6.

(17)

Nitenberg, A., Valensi, P., Sachs, R., Dali, M., Aptecar, E., & Attali, J. R. (1993). Impairment of coronary vascular reserve and ACh-induced coronary vasodilation in diabetic patients with angiographically normal coronary arteries and normal left ventricular systolic function. Diabetes 42, 1017–1025.

Nowak B, Sinha AM et al.(2003) Cardiac resynchronization therapy homogenizes myocardial glucose metabolism and perfusion in diated cardiomyopathy and left bundle branch block. J Am Coll Cardiol; 41: 1523-8.

Ohara, Y., Peterson, T. E., & Harrison, D. G. (1993). Hypercholesterolemia increases endothelial superoxide anion production. J Clin Invest 91, 2546–2551.

Oliver MR, Kurien VA, Greenwook TW.(1968) Relation between serum-free-fatty acids and arrhythmia and death after myocardial infarction. Lancet ;i:710– 715.

Opie,LH. (1991) The Heart. Physiology and metabolism. New York: Raven,

Osborne, J. A., Siegman, M. J., Sedar, A. W., Mooers, S. U., & Lefer, A. M. (1989). Lack of endothelium-dependent relaxation in coronary resistance arteries of cholesterol-fed rabbits. Am J Physiol 256 (3 Pt 1), C591–C597.

Osorio JC et al.(2002) Impaired myocardial fatty acid oxidation and reduced protein expression of retinoid X receptor alpha in pacing induced heart failure. Circulation;106: 606-612.

Ozawa E, Noguchi S, Mizuno Y, Hagiwara Y, Yoshida M. (1998) From dystrophinopathy to sarcoglycanopathy: evolution of a concept of muscular dystrophy. Muscle Nerve; 21: 421– 38.

Palmer, R. M. J., Ashton, D. S., & Moncada, S. (1988). Vascular endothelial cells synthesize nitric oxide from L-arginine. Nature 333, 664–666.

Parodi O, De Maria R, Oltrona L, Testa R, Sambuceti G, Roghi A, Merli M, Belingheri L, Accinni R, Spinelli F, Pellegrini A, Baroldi G.(1993) Myocardial blood flow distribution in

(18)

patients with ischemic heart disease or dilated cardiomyopathy undergoing heart transplantation. Circulation.;88:509-522.

Pasternac A, Noble J, Streulens Y, Elie R, Henschke C, Bourassa MG. (1982) Pathophysiology of chest pain in patients with cardiomyopathies and normal coronary arteries. Circulation.;65:778-89.

Pereztol-Valdes O, Candell-Riera J, Santana-Boado C, Aguade´-Bruix JAS, Castell-Conesa Garcia EV, Soler-Soler J (2005) Correspondence between left ventricular 17 myocardial segments and coronary arteries European Heart Journal 26, 2637–2643

Piano MR (2002) Alcoholic cardiomyopathy: incidence, clinical characteristics and pathophysiology. Chest 121:1638.

Pohl, U., Holtz, J., Busse, R., & Bassenge, E. (1986). Crucial role of endothelium in the vasodilation response to increased flow in vivo. Hypertension 8, 37–44.

Pupita GS, Maseri A, Kaski JC et al: (1990) Myocardial ischemia caused by distal coronary artery constriction in stable angina pectoris. New Engl J Med;323:514-520.

Quillen, J. E., Sellke, F. W., Armstrong, M. L., & Harrison, D. G. (1991). Long-term cholesterol feeding alters the reactivity of primate coronary microvessels to platelet products. Arterioscler Thromb 11, 639–644.

Quyyumi, A. A., Mulcahy, D., Andrews, N. P., Husain, S., Panza, J. A., & Cannon, R. O., III. (1997b). Coronary vascular nitric oxide activity in hypertension and hypercholesterolemia. Comparison of acetylcholine and substance P. Circulation 95, 104– 110.

Randle PJ, England PJ, Denton RM (1970) Control of the tricarboxylate cycle and its interactions with glycolisis during acetate utilization in rat heart Biochem J 117:677-695.

(19)

Rajagopalan, S., Dube, S., & Canty, J. M., Jr. (1995). Regulation of coronary diameter by myogenic mechanisms in arterial microvessels greater than 100 microns in diameter. Am J Physiol. 268 (2 Pt 2), H788–H793.

Razeghi P Young AE et al.(2001) Metabolic gene expression in fetal and failing human heart. Circulation; 104: 2923-31.

Recchia F. 2002)Role of nitric oxide in the regulation of substrate metabolism in heart failure. Heart failure reviews2;7: 141-8.

Recchia F et al. (2002) Reduced synthesis of NO causes marked alterations in myocardial substrate metabolism in conscious dogs. Am J Physiol Endocrinol Metab;282: E197-E206. Recchia FA, McConnell PI, Bernstein RD, Vogel TR, Xu X, and Hintze TH. (1998) Reduced nitric oxide production and altered myocardial metabolism during the decompensation of pacing-induced heart failure in the conscious dog. Circ Res 83: 969–979. Rigel, D. F., & Lappe, R. W. (1993). Differential responsiveness of conduit and resistance coronary arteries to endothelin A and B receptor stimulation in anesthetized dogs. J Cardiovasc Pharmacol 22(suppl. 8), S243–S247.

Rubanyi, G. M., Romero, J. C., & Vanhoutte, P. M. (1986). Flow-induced release of endothelium-derived relaxing factor. Am J Physiol 250 (6 Pt 2), H1145–H1149. (4 Pt 2), H1571–H1581.

Rupp, H., Zarain-Herzberg, A., & Maisch, B. (2002). The use of partial Fatty Acid oxidation inhibitors for metabolic therapy of angina pectoris and heart failure. Herz 27, 621-636.

Sack MN, Rader TA, Park S.(1996) Fatty acids oxidation enzyme gene expression is downregulated in the failing heart. Circulation; 94: 2837-42.

Saddik M, Gamble J, Witters LA, and Lopaschuk GD. (1993) Acetyl-CoA carboxylase regulation of fatty acid oxidation in the heart. J Biol Chem 268: 25836–25845.

(20)

Sambuceti G, Parodi O, Marzullo P, et al. (1993) Regional myocardial blood flow in stable angina pectoris associated with isolated significant narrowing of either the left anterior descending or left circumflex coronary artery. Am J Cardiol.;72:990-994.

Sambuceti G, Marzullo P, Giorgetti A et al. (1994) Global alteration in perfusion response to increasing oxygen consumption in patients with single-vessel coronary artery disease. Circulation;90:1696–1705.

Sambuceti G, Giorgetti A, Corsiglia L, et al. (1998) Perfusion-contraction mismatch during inotropic stimulation in hibernating myocardium. J Nucl Med.;39:396–402.

Sato, K., Kanatsuka, H., Sekiguchi, N., Akai, K., Wang, Y., Sugimura, A., Kumagai, T., Komaru, T., & Shirato, K. (1994). Effect of an ATP sensitive potassium channel opener, levcromakalim, on coronary arterial microvessels in the beating canine heart. Cardiovasc Res 28, 1780–1786.

Schaffer JE (2002) Fatty acids transport: the roads taken. Am J Physiol Endocrinol Metab 282: E239-E246.

Schwartzkopff, B., Motz, W., Frenzel, H., Vogt, M., Knauer, S., & Stauer, B. E. (1993). Structural and functional alterations of the intramyocardial coronary arterioles in patients with arterial hypertension. Circulation 88, 993–1003.

Sellke, F. W., Armstrong, M. L., & Harrison, D. G. (1990a). Endotheliumdependent vascular relaxation is abnormal in the coronary microcirculation of atherosclerotic primates. Circulation 81, 1586–1593.

Sellke, F. W., Wang, S. Y., Friedman, M., Harada, K., Edelman, E. R., Grossman, W., & Simons, M. (1994). Basic FGF enhances endothelium- dependent relaxation of the collateral-perfused coronary microcirculation. Am J Physiol 267 (4 Pt 2), H1303–H1311. Sellke, F. W., Quillen, J. E., Brooks, L. A., & Harrison, D. G. (1990c). Endothelial

(21)

modulation of the coronary vasculature in vessels perfused via mature collaterals. Circulation 81, 1938–1947.

Sellke, F. W., Myers, P. R., Bates, J. N., & Harrison, D. G. (1990b). Influence of vessel size on the sensitivity of porcine coronary microvessels to nitroglycerin. Am J Physiol 258 (2 Pt 2), H515–H520

Shen, W., Xu, X., Ochoa, M., Zhao, G., Wolin, M. S., & Hintze, T. H. (1994). Role of nitric oxide in the regulation of oxygen consumption in conscious dogs. Circ Res 75, 1086–1095. Stanley WC, Chandler MP.(2002) Energy metabolism in the normal and failing heart: potential for therapeutic interventions. Heart Fail Rev;7:115–30.

Stanley WC, Hall JL, Stone CK, Hacker TA. (1992) Acute myocardial ischemia causes a transmural gradient in glucose extraction but not glucose uptake. Am J Physiol.;262:H91– H96.

Sudhir, K., Chou, T. M., Mullen, W. L., Hausmann, D., Collins, P., Yock, P. G., & Chatterjee, K. (1995). Mechanisms of estrogen-induced vasodilation: in vivo studies in canine coronary conductance and resistance arteries. J Am Coll Cardiol 26, 807–814.

Sutherland, C. G., Fisher, B. M., Frier, B. M., Dargie, H. J., More, I. A., & Lindop, G. B. (1989). Endomyocardial biopsy pathology in insulindependent diabetic patients with abnormal ventricular function. Histopathology 14, 593–602.

Suzuki, H., DeLano, F. A., Parks, D. A., Jamshidi, N., Granger, D. N.,n Ishii, H., Suematsu, M., Zweifach, B. W., & Schmid-Schönbein, G. W. (1998). Xanthine oxidase activity associated with arterial blood pressure in spontaneously hypertensive rats. Proc Natl Acad Sci USA 95,n 4754–4759.

Taegtmeyer H, Hems R, Krebs A (1980) Utilization of energy providing substrate in the isolated working rat heart. Biochem J 186:701-707.

(22)

Taegtmeyer H. (1994) Energy metabolism of the heart: from basic concepts to clinical applications. Curr Prob Cardiol 19: 59–113.

Tanaka, M., Fujiwara, H., Onodera, T., Wu, D. J., Matsuda, M., Hamashima, Y., & Kawai, C. (1987). Quantitative analysis of narrowings of intramyocardial small arteries in normal hearts, hypertensive hearts and hearts with hypertrophic cardiomyopathy. Circulation 75, 1130–11

Taylor MR, Fain PR, Sinagra G(2003) Natural history nof Dilated Cardiomyopathy due to lamin A/C gene J Am Coll Cardiol 41:771.

Tesfamariam, B., Brown, M. L., Deykin, D., & Cohen, R. A. (1990). Elevated glucose promotes generation of endothelium-derived vasoconstrictor prostanoids in rabbit aorta. J Clin Invest 85, 929–932.

Tomai F, Ribichini F, Ghini AS et al . (2005) Elevated C-reactive protein levels and coronary microvascular dysfunction in patients with coronary artery disease. Eur Heart J;26:2099-105.

Urakami-Harasawa, L., Shimokawa, H., Nakashima, M., Egashira, K., & Takeshita, A. (1997). Importance of endothelium-derived hyperpolarizing factor in human arteries. J Clin Invest 100, 2793–2799.

Uren NG, Marraccini P, Gistri R, de Silva R, Camici PG.(1993) Altered coronary vasodilator reserve and metabolism in myocardium subtended by normal arteries in patients with coronary artery disease. J Am Coll Cardiol.;22:650-658.

Vatner, D. E., Knight, D. R., Homcy, C. J., Vatner, S. F., & Young, M. A. (1986). Subtypes of b-adrenergic receptors in bovine coronary arteries. Circ Res 59, 463–473.

Vitale, C., Wajngaten, M., Sposato, B., Gebara, O., Rossini, P., Fini, M., Volterrani, M., & Rosano, G. M. (2004). Trimetazidine improves left ventricular function and quality of life in elderly patients with coronary artery disease. Eur Heart J 25, 1814-1821.

(23)

Vitullo, J. C., Penn, M. S., Rakusan, K., & Wicker, P. (1993). Effects of hypertension and aging on coronary arteriolar density. Hypertension 21, 406–414.

Van den Heuvel, van Veldhuisen DJ (2000) Regional myocardial blood flow reserve impairment and metabolic changes suggesting myocardial ischemia in patients with dilated cardiomyopathy J Am Coll Cardiol; 35:19-28.

Van der Vusse GJ (2001)Cardiac fatty acids uptake and transport in health and disease. Cardiovasc Res 14;876.

Wallhaus TR Taylor M. (2001)Myocardial free fatty acids and glucose use agter carvedilol treatment in patients with congestive heart failure. Circulation; 103:2441-8.

Wang, S. Y., Friedman, M., Johnson, R. G., Weintraub, R. M., & Sellke, F. W. (1994). Adrenergic regulation of coronary microcirculation after extracorporeal circulation and crystalloid cardioplegia. Am J Physiol 267 (6 Pt 2), H2462–H2470.

Watanabe J et al. (2000) Constitutive regulation of cardiac fatty acid metabolism through PPAR alpha associated with age dependent cardiac toxicity. J Bioc Chem.: 275:2160-65. Weiss MB, Ellis K, Sciacca RR, Johnson LL, Schmidt DH, Cannon PJ.(1976) Myocardial blood flow in congestive and hypertrophic cardiomyopathy: relationship to peak wall stress and mean velocity of circumferential fiber shortening. Circulation.;54:484-493

Wieneke H, Clemens von Birgelen, Michael Haude, Holger Eggebrecht, (1995) Determinants of coronary blood flow in humans: quantification by intracoronary Doppler and ultrasound Journal of Applied Physiology 98:1076-1082.

Wilcox, J. N., Subramanian, R. R., Sundell, C. L., Tracey, W. R., Pollock, J. S., Harrison, D. G., & Marsden, P. A. (1997). Expression of multiple isoforms of nitric oxide synthase in normal and atherosclerotic vessels. Arterioscler Thromb Vasc Biol 17, 2479–2488.

(24)

Wijns W, Vatner SF, Camici PG.(1998) Hibernating myocardium. N Engl J Med;339:173– 81.

Yarom, R., Zirkin, H., Stammler, G., & Rose, A. G. (1992). Human coronary microvessels in diabetes and ischemia: morphometric study of autopsy material. J Pathol 166, 265–270. Yazaki Y, Isobe M, Takahashi W, Kitabayashi H, Nishiyama O, Sekiguchi M, and Takemura T. (1999) Assessment of myocardial fatty acid metabolic abnormalities in patients with idiopathic dilated cardiomyopathy using 123I BMIPP SPECT: correlation with clinicopathological findings and clinical course. Heart 81: 153–159.

Zeiher, A. M., Drexler, H., Wollschläger, H., & Just, H. (1991). Modulation of coronary vasomotor tone in humans. Progressive endothelial dysfunction with different early stages of coronary atherosclerosis. Circulation 83, 391–401.

Zeiher AM, Schachinger V, Minners J.(1995) Long-term cigarette smoking impairs endothelium-dependent coronary arterial vasodilator function. Circulation;92:1094-100

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