Tab 2- Clinical Variables: distribution in the three groups, statistical analyses performed and significance levels.

Tab 2- Clinical Variables: distribution in the three groups, statistical analyses performed and significance levels.

* the analyse revealed significant difference between groups

1 _{Mn: Manic, Hy: Hypomanic, Dp: Depressive, Mx: Mixed} 2 _{% of subjects attempted suicide at least one time}

3 _{I: Manic phase – Depressive phase – Free interval; II D – M – F; III: M – F – D}

IV: D – F – M

4 _{Con: Continous, Rpd. Rapids, Irr: Irregulars} Disorder

Clinical

Bipolar 1 Bipolar 2 Major Depression

Value Test Sig.

Age of Onset _{26,9±8,3 30,2±10,1 33,2±11,7} Mean ANOVA 0.000*

IllnessDuration _{12,6±10,6 16,4±9,7 15,31±11,81} 0.053 Mn 41,9% Hy 2,6% Hy 30,1% Dp 42,6% First Episode1 Mx 12,8% Dp 60,9% Dp 100% Row%

All Episodes _{5±7 8±15 4±4} Median Kruskal-Wallis 0.000*

Tot.Manic _2±3.25 - - Median Kruskal-Wallis 0.000*

Tot.Hypomanic 0±0 3±8 - Median Kruskal-Wallis 0.000*

Tot.Depressive _{2±4 4±7 4±4} Median Kruskal-Wallis 0.010*

Tot.Mixed _0±0.25 - - Median Kruskal-Wallis 0.000*

Suicide Attempt2 28,6% 26,9% 16,2% Row% 0.163 I 28.1% I 15.1% II 29.2% II 39.7% III 13.5% III 8.2% Course3 IV 29.2% IV 37.0% Row% Kruskal-Wallis 0.167 Con 22,8% Con 18,9% Rpd 12,3% Rpd 24,3% Cycles4 Irr 64,9% Irr 56,8% Row% Kruskal-Wallis 0.642