BIBLIOGRAFIA
Antoniou, Pharoah, P.D.P., Narod, S., Risch, H.A., Eyfjord, J.E., Hooper, J.L., Loman, N., Olsson, H., Johannsson, O., Borg, et al (2003). Average Risks of Breast and Ovarian Cancer Associated with BRCA 1 or BRCA 2 Mutations Detected in Case Series Unselected for Family History: A combined Analysis of 22 studies. American Journal of Human Genetics, 72, 1117-1130.
Apostolou J., Sarli G., Capitani O., Marcato P.S. Considerazioni prognostiche su lesioni preneoplastiche e neoplastiche multiple della ghiandola mammaria del cane e del gatto, Veterinaria, 1998.
Armstrong, A.C., & Evans, G.D. (2014). Management of women at high risk of breast cancer. British Medical Journal , 348: g2756.
Barone R. Anatomia comparata dei mammiferi domestici; Vol. 4° Splancnologia. Edagricole, 2003.
Benjamin SA, Lee AC, Saunders WJ. Classification and behavior of canine mammary epithelial neoplasms based on life-span observations in beagles. Vet Pathol 36:423–436, 1999.
Bennett L.M, Brownlee H.A., Hagavik S., Wiseman R.W. Sequence analysis of the rat Brca1homolog and its promoter region. Mammalian Genome. 19-25, 1999.
Bignell G, Micklem G, Stratton MR, Ashworth A and Wooster R (1997) The BRC repeats are conserved in mammalian BRCA2 proteins. Hum Mol Genet 6, 53–58.
Bodner-Adler B, Bodner K, Zeisler H. Breast cancer diagnosed during pregnancy. Anticancer Res. 2007 May-Jun; 27(3B):1705-7.
Bonney RC, Reed MJ, Beranek PA, Ghilchik MW, James VHT. Metabolism of [3H]oestradiol in vivo by normal breast and tumor tissue in postmenopausal women. I Steroid Biochem 1986; 24:361-4.
Borge KS, Børresen-Dale AL, Lingaas F (2011) Identification of genetic variation in 11 candidate genes of canine mammary tumour. Vet Comp Oncol 9(4):241–250.
Brodey R.S, Goldschmidt M.H., Roszel J.R.. Canine mammary neoplasm. Journal of the american animal hospital association, 1983, 19:61–90.
Calistri D.; Zampiga V.; Zoli W. Characterization of molecular alterations of BRCA1/2: Analysis and interpretation guidelines. Current Women's Health Reviews. 2012;;8(1):4-11. Calle EE, Thun MJ. Obesity and cancer. Oncogene 2004;23:6365^78.
Casagrande M. Studio dell’espressione nel tumore mammario del cane del recettore HER2/Neu e correlazioni prognostiche. Università degli studi di Padova, AA 2006-2007.
Chandra SA, Mark Cline J, Adler RR: Cyclic morphological changes in the beagle mammary gland. Toxicol Pathol 38:969-83, 2010.
Chang C.H., Liu C.H., Conway R., Han D.K., Nithipatilom K., Trifan O.C., Lane T.F., Hla T.. Role of prostaglandin E2-dependent angiogenic switch in cyclooxygenase-2induced breast cancer progression. Proc Natl, Acad Sci, 2004, 101(2): 591–596.
Chang SC, Chang CC, Chang TJ, Wong ML: Prognostic factors associated with survival two years after surgery in dogs with malignant mammary tumors: 79 cases (1998–2002). J Am Vet Med Assoc 227:1625–1629, 2005.
Chen J, Silver DP, Walpita D, Cantor SB, Gazdar AF, Tomlinson G, Couch FJ, Weber BL, Ashley T, Livingston DM, Scully R. Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells. Mol Cell 2: 317-28, 1998.
Chung-Ho L., Wan-Hee K., Ji-Hey L., Min-Soo K., Dae-Yong K., e Oh Kyeong K.. Mutation and overexpresion of p53 as a prognostic factor in canine mammary tumors. J. Vet. Sci., 5(1):63–69, 2004.
Clemente M., Pérez-Alenza M.D., Illera J.C., Pena L.. Histological, immunohistological, and ultrastructural description of vasculogenic mimicry in canine mammary cancer. Vet Pathol, 2010, 47(2): 265–274.
Clevenger CV, Plank TL. Prolactin as an autocrine/ paracrine factor in breast cancer. J Mammary Gland Biol Neoplasia. 1997;2:59–68.
Cortez D., Wang Y. et al.: ”Requirement of ATM-dependent phosphorylation on BRCA1 in the DNA damage response to double- strand breaks. Science 1999; 286: 1162-6.
Cosmi, Ermelando Pinotti, Josè. Neoplasie della mammella. Dalla diagnosi al trattamento. Editore: SEE Editore, 2006.
Dabrosin C, Margetts PJ, Gauldie J. Estradiol increases extracellular levels of vascular endothelial growth factor in vivo in murine mammary cancer. Int J Cancer 2003;107:535–40. Daleck CR, Franceschini PH, Alessi AC, Santana AE, Martins MIM: Aspectos clínico e
cirúrgico do tumor mamário canino. Ciência Rural 1998, 28:95-100.
De Paola F. Ricerca nella popolazione italiana dei loci di suscettibilità al carcinoma tiroideo differenziato, precedentemente identificati nella popolazione islandese. Università degli studi di Pisa, AA 2010-2011.
Dobson, J.M., Duncan, B., Lascelles, X. (2003): Bsava Manual Of Canine And Feline Oncology. Bsava, 234-239.
Doisneau-Sixou S.F., Sergio C.M, Carroll J.S., Hui R., Musgrove E.A., Sutherland R.L. Estrogen and antiestrogen regulation of cell cycle progression in breast cancer cells. Endocrine-related cancer, 2003, 10:179–186.
Donnay I., Devleeschouwer N., Wouters-Ballman P., Leclerq G., e Versteegen J.P.. Relationship between receptors for epidermal growth factor and steroid hormones in normal and neoplastic canine mammary tissue. Research in Veterinary Science, 60(3):251–254, 1996. Dorn C.R. e Schneider R.. Imbreeding and canine mammary cancer. A retrospective study. J.
Natl. Cancer Inst., 57(3):545–548, 1976.
Egenvall, B. N. Bonnett, P. Öhagen, P. Olson, A. Hedhammar, and H. Von Euler. Incidence of and survival after mammary tumors in a population of over 80,000 insured female dogs in Sweden from 1995 to 2002. Preventive Veterinary Medicine, vol. 69, no. 1-2, pp. 109–127, 2005.
Eigenmann JE, Eigenmann RY, Rijnberk A, van der Gaag I, Zapf J, et al. (1983) Progesterone-controlled growth hormone overproduction and naturally occurring canine diabetes and acromegaly. Acta Endocrinol (Copenh) 104: 167–176.
Eisen A, Lubinski J, Klijn J, Moller P, Lynch HT, Offit K, Weber B, Rebbeck T, Neuhausen SL, Ghadirian P, Foulkes WD, Gershoni-Baruch R, Friedman E, Rennert G, Wagner T, Isaacs C, Kim-Sing C, Ainsworth P, Sun P, Narod SA. Breast cancer risk following bilateral oophorectomy in BRCA1 and BRCA2 mutation carriers: an international case-control study. J Clin Oncol. 2005 Oct 20;23(30):7491-6.
Enginler SO, Akis I, Toydemir TS, Oztabak K, Haktanir D, Gunduz MC, Kirsan I and Firat I (2014) Genetic variations of BRCA1 and BRCA2 genes in dogs with mammary tumours. Vet Res Commun 38, 21–27.
Ettinger SJ, Feldman EC. Clinica Medica Veterinaria. Malattie del cane e del gatto. 6th edition. Ed Elsevier, 2008.
Fan S, Wang J, Yuan R, Ma Y, Meng Q, Erdos MR, Pestell RG, Yuan F, Auborn KJ, Goldberg ID, Rosen EM. BRCA1 inhibition of estrogen receptor signaling in transfected cells. Science 284: 1354-6, 1999.
Faratian D.. Systems pathology. Brast cancer research, 2010, 12(4):S4.
Fearon ER. Human cancer syndromes: clues to the origin and nature of cancer. Science 278: 1043-50, 1997.
Francken, A.B., Schouten, P.C., Bleiker, E.M.A., Linn, S.C. (2013). Breast cancer in women at high risk: The role of rapid genetic testing for BRCA 1 and -2 mutations and the consequences for treatment strategies, The Breast, Elsevier, 22, 561- 568.
Garofalo C, Surmacz E. Leptin and cancer. J Cell Physiol 2006;207:12^ 22.
Gelbfish GA, Davidson AL, Kopel S, Schreibman B, Gelbfish JS, Degenshein GA, Herz BL and Cunningham JN: Relationship of estrogen and progesterone receptors to prognosis in breast cancer. Ann Surg 207: 75-79, 1988.
Gollamudi SV, Gelman RS, Peiro G, Schneider LJ, Schnitt SJ, Recht A, et al: Breast-conserving therapy for stage I-II synchronous bilateral breast carcinoma. Cancer 79:1362-9, 1997.
Gowen LC, Avrutskaya AV, Latour AM, Koller BH, Leadon SA (1998) BRCA1 required for transcription-coupled repairof oxidativeDNA damage. Science 281:1009–1012
Grammatico P., Il ruolo della genetica nella valutazione dei rischi nel Carcinoma della mammella, 2013.
Gruvberger-Saal SK, Bendahl PO, Saal LH, Laakso M, Hegardt C, Eden P, Peterson C, Malmstrom P, Isola J, Borg A and Ferno M: Estrogen receptor beta expression is associated with tamoxifen response in ERalpha-negative breast carcinoma. Clin Cancer Res 13: 1987-1994, 2007.
Haga S., NakayamaM., e Tatsumi K.. Overexpression of the p53 gene product in canine mammary gland tumors. Oncol. Rep., 8(6):1215–1219, 2001.
Hampe JF, Misdorp W. Tumours and dysplasias of the mammary gland. Bull World Health Organ. 1974;50(1-2):111-33.
Hanahan D. e Weinberg R.A. The hallmarks of cancer. Cell, 100:57–70, 2000.
Helewa M, Levesque P, Provencher D, Lea RH, Rosolowich V, Shapiro HM. Breast cancer, pregnancy, and breastfeeding. J Obstet Gynaecol Can, 24:164-180, 2002.
Hellmén E. e Lindgren A. The accuracy of cytology in diagnosis and DNA analysis of canine mammary tumours. J.Comp.Pathol.,101:443–450, 1989.
Hellmèn E, Bergstrom R, Holmberg L: Prognostic factors in canine mammary gland tumors: a multivariate study of 202 consecutive cases. Vet Pathol 30:20–27, 1993.
Hilakivi-Clarke L. Estrogens, BRCA1, and breast cancer. Cancer Res 60: 4993-5001, 2000. Huyton T, Bates PA, Zhang X, Sternberg MJ, Freemont PS. The BRCA1 Cterminal domain:
structure and function. Mutat Res. 2000; 460(3-4): 319-32.
Illera Juan C., Pérez-Alenza Maria D, Nieto Ana, Jiménez Maria A, Silvan Gema, Dunner Susana, et al. Steroids and receptors in canine mammary cancer. Steroids 71 (7): 541-8, 2006.
Innocenti V.M. Le neoplasie mammarie della cagna: valutazione clinica dei fattori di rischio e prognostici. Università degli studi di Pisa; AA 2010-2011.
Itoh T., Uchida K., Ishikawa K. et al., “Clinicopathological survey of 101 canine mammary gland tumors: differences between small-breed dogs and others,” Journal of Veterinary Medical Science, vol. 67, no. 3, pp. 345–347, 2005.
Jardé, T., Caldefie-Chezet, F., Damez, M., Mishellany, F., Penault-Llorca, F., Guillot, J., Vasson, M.P., 2008. Leptin and leptin receptor involvement in cancer development: A study on human primary breast carcinoma. Oncology Reports 19, 905–912.
Karayannopolou M., Kaldrymidou E., Constantinidis T.C., Dessiris A.. Histological grading and prognosis in dogs with mammary carcinomas: application of a human grading method. J. Comp path, 2005, 133:246–252.
Kinzler, K.W. and B. Vogelstein, Cancer-susceptibility genes. Gatekeepers and caretakers. Nature, 1997. 386(6627): p. 761, 763.
Klopfleisch R, Gruber AD: Increased expression of BRCA2 and RAD51 in lymph node metastases of canine mammary adenocarcinomas. Vet Pathol 46:416–422, 2009
Knudson, A.G., Jr., H.W. Hethcote, and B.W. Brown, Mutation and childhood cancer: a probabilistic model for the incidence of retinoblastoma. Proceedings of the National Academy of Sciences of the United States of America, 1975. 72(12): p. 5116-20.
Korach K.S., Couse J.F., Curtis S.W., Washburn T.F., Lindzey J., Kimbro K.S, Eddy E.M., Miglaccio A., Snedeker S.M, Lubahn D.B, Schomberg D.W, Smith E.P. Estrogen receptor gene disruption: molecular characterization and experimental and clinical phenotypes. Rec Prog Horm Res, 1996, 51:159–186.
Kumar, V., Abbas, A.K., Fausto, N., 2005. Neoplasia. In: Kumar, V., Abbas, A.K., Fausto, N. (Eds.), Robbins and Cotran Pathologic Basis of Disease, 7th ed. Elsevier Saunders, Philadelphia, USA.
Langer A, Mohallem M, Stevens D, Rouzier R, Lerebours F, Chérel P. A single-institution study of 117 pregnancy-associated breast cancers (PABC): Presentation, imaging, clinicopathological data and outcome. Diagn Interv Imaging. 2014 Apr; 95(4):435-41.
Laud, K., Gourdou, I., Pessemesse, L., Peyrat, J., Djiane, J., 2002. Identification of leptin receptors in human breast cancer: Functional activity in the T47-D breast cancer cell line. Molecular and Cellular Endocrinology 188, 219–226.
Lorick KL, Jensen JP, Fang S, Ong AM, Hatakeyama S, Weissman AM. RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination. Proc Natl Acad Sci U S A. 1999; 96(20): 11364-9.
Lorincz, A.M., Sukumar, S., 2006. Molecular links between obesity and breast cancer. Endocrine-Related Cancer 13, 279–292.
Lynch HT, Harris RE, Guirgis HA, Maloney K, Carmody LL, Lynch JF. Familial association of breast/ovarian carcinoma. Cancer 41: 1543-9, 1978 .
Lynch HT, Krush AJ, Lemon HM, Kaplan AR, Condit PT, Bottomley RH. Tumor variation in families with breast cancer. JAMA 222: 1631-5, 1972.
Lyndon J.P., De Mayo F.J., Funk C.R., Mani S.K., Hughes A.R., Montgomery C.A., Shyamala G., Conneely O.M., O'Malley B.W. Mice lacking progesterone receptor exhibit pleiotrophic reproductive abnormalities. Genes Dev. 1995, 9:2266–2278.
Marconato L, Del Piero F. Oncologia medica dei piccoli animali. Poletto editore, 2005.
Marks JR, Huper G, Vaughn JP, Davis PL, Norris J, McDonnell DP, Wiseman RW, Futreal PA, Iglehart JD. BRCA1 expression is not directly responsive to estrogen. Oncogene 14: 115-21, 1997.
Marmorstein L.Y., Kinev A.V. et al. A human BRCA2 complex containing a structural DNA binding component influences cell cycle progression. Cell 2001; 104: 247–57.
Marquis ST, Rajan JV, Wynshaw-Boris A, Xu J, Yin G-Y, Abel KJ, Weber BL, Chodosh LA. The developmental pattern of Brca1 expression implies a role in differentiation of the breast and other tissues. Nat Genet 11: 17-26, 1995.
Martin de las Mulas J, Ordas J, Millan MY, Chacon F, De Lara M, Espinosa de los Monteros A, Reymundo C and Jover A: Immunohistochemical expression of estrogen receptor beta in normal and tumoral canine mammary glands. Vet Pathol 41: 269-272, 2004.
McGavin M.D., Zachary J.F.. Patologia veterinaria sistematica. Edizione italiana a cura di Massimo Castagnaro Edizione,4 ed, Milano Elsevier Masson, 2010.
Miki Y, Swensen J, Shattuck-Eidens D et al. A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science 1994; 266: 66–71.
Millanta F., Citi S., Della Santa D., Porciani M., Poli A.. Cox-2 expression in canine and feline invasive mammary carcinomas: correlation with clinicopathological features and prognostic molecular markers. Breast Cancer Research and Treatment, 2006, 98: 115– 120.
Misdorp W, Else RW, Hellmen E, Lipscomb TP. Histological classification of mammary tumors of the dog and the cat. Armed Forces Institute of Pathology: American Registry of Pathology: World Health Organization Collaborating Center for Comparative Oncology, 1999. Misdorp W: Tumors of the Mammary Gland. In: Tumors in Domestic Animals, ed. Meuten DJ,
Moe L. Population-based incidence of mammary tumors in some dog breeds. J Reprod Fertil Suppl 57:439–443, 2001.
Moinfar F, Okcu M, Tsybrovskyy O, Regitnig P, Lax SF, Weybora W, Ratschek M, Tavassoli FA, Denk H. Androgen receptors frequently are expressed in breast carcinomas: potential relevance to new therapeutic strategies. Cancer 2003;98:703–11.
Morris JS Dobson JM, Bostock DE, O’Farrell E. Effect of ovariohysterectomy in bitches with mammary neoplasm. Vet Rec 142:656- 658, 1998.
Morris JR, Solomon E. “BRCA1 : BARD1 induces the formation of conjugated ubiquitin structures, dependent on K6 of ubiquitin, in cells during DNA replication and repair” Hum Mol Genet. 2004; 13(8): 807-17.
Moulton JE, Rosenblatt LS, Goldman M: Mammary tumors in a colony of beagle dogs. Vet Pathol 23:741–749, 1986.
Moulton J.E. Tumors of the mammary gland In Tumors in Domestic Animals. A cura di Moulton J.E. ed., pp. 518–522. Univ. California Press, Berkeley, 3rd edizione, 1990.
Murphy LC, Watson P (2002) Steroid receptors in human breast tumorigenesis and breast cancer progression. Biomedicine and Pharmacotherapy, 56, 65e77.
Nargotra N, Kalita D. J Clin. Pregnancy Associated Breast Cancer: Awareness is the Key to Diagnosis - A Case Report. Diagn Res. 2015 Nov ;9(11).
Nerurkar VR, Chitale AR, Jalnapurkar BV, Naik SN, Lalitha VS: Comparative pathology off canine mammary tumors. J Comp Pathology 1989, 101:88-397.
Nickel R., Schummer A., Seiferle E. The Anatomy of the Domestic Animals Volume 3, 1984. Nieto A, Peña L, Perez-Alenza MD, Sanchez MA, Flores JM, Castan˜ o M. Immunohistologic
detection of estrogen receptor alpha in canine mammary tumors: clinical and pathologic associations and prognostic significance. Vet Pathol 2000;37:239–47.
Nieto A, Perez-Alenza MD, Del Castillo N, Tabanera E, Castano M, Pena L. BRCA1 expression in canine mammary dysplasias and tumours: relationship with prognostic variables. J Comp Pathol 2003;128:260–8.
Noruzinia M, Coupier I, Pujol P. Is BRCA1/BRCA2-related breast carcinogenesis estrogen dependent? Cancer. 2005 Oct 15;104(8):1567-74.
Ochiai K, Morimatsu M, Tomizawa N, Syuto B. Cloning and sequencing full length of canine Brca2 and Rad51 cDNA. J Vet Med Sci. 2001 Oct;63(10):1103-8.
Ochiai K, Morimatsu M, Yoshikawa Y, Syuto B, Hashizume K (2004) Brca2 C-terminus interacts with Rad51 and contributes to nuclear focusformation in double-strand breakrepairofDNA. BiomedRes 25:269–275.
Ogilivie GK, Moore AS. Nutritional support. In Managing the veterinary cancer patient: a practice manual. Trenton VLS ed 124-127, 1995.
Ogilivie GK. Neoplasie. In Le neoplasie del cane. Hill’s Pet Nutrition Inc. 70, 1999.
Orfanou D.C, Pourlis A., Ververidis H.N., Mavrogianni V.S., Taitzoglou I.A, Boscos C.M. Histological features in the mammary glands of female dogs throughout lactation. Journal of Veterinary Medicine, Anat. Histol. Embryol. 2010, 39:473–478.
Osborne CK, Schiff R, Arpino G, Lee AS, Hilsenbeck VG (2005) Endocrine responsiveness: understanding how progesterone receptor can be used to select endocrine therapy. Breast, 14, 458e465.
Pagliaretta S. Tumori eredo-familiari di mammella e ovaio: analisi mutazionale dei geni BRCA1 e BRCA2. Facoltà di Medicina e Chirurgia, Università Politecnica delle Marche. AA 2011-2012.
Patsikas M.N., Karayannopoulou M., Kaldrymidoy E., Papazoglou L.G., Papadopoulou P.L., Tzegas S.I., Tziris N.E., Kaitzis D.G., Dimitriadis A.S., Dessiris A.K. The lymph drainage of the neoplastic mammary glands in the bitch: a lymphographic study. Anat Histo Embryol, 2006, 35:228–234.
Peaker M. Endocrine signals from the mammary gland. J Endocrinol. 1995;147(2):189–193. Peleteiro MC: Tumores mamários na cadela e na gata. Revista Portuguesa de Ciências
Veterinárias 1994, 89:10-29.
Pellegrini L, Yu DS, Lo T, Anand S, Lee M, Blundell TL, Venkitaraman AR. Insights into DNA recombination from the structure of a RAD51-BRCA2 complex. Nature. 2002 Nov 21;420(6913):287-93.
Peña L, Perez-Alenza MD, Rodriguez-Bertos A, Nieto A. Canine inflammatory mammary carcinoma. Histopathology, immunohistochemistry and clinical implications of 21 cases. Breast Cancer Res Treat 2003;78:141–8.
Pérez-Alenza M.D., Rutteman G.R, Pena L.: Relation between habitual diet and canine mammary tumors in a case-control study. J Vet Intern Med, 1998, 12:132–139.
Perez Alenza MD, Peña L, del Castillo N, Nieto AI: Factors influencing the incidence and prognosis of canine mammary tumours. J Small Animal Pract 41:287-91, 2000.
Perez Alenza M.D., Tabanera E., e Pena L. Inflammatory mammary carcinoma in dogs: 33 cases (1995-1999). J. Am. Vet. Med. Assoc., 219(8):1110–1114, 2001.
Pierotti. M.A, Sozzi, G., Croce, C.M., 2003a. Discovery and identification of oncogenes. In: Kufe, D.W, Pollock, R.E, Weichselbaum, R.R. (Eds.), Holland-Frei Cancer Medicine, 6th ed. Hamilton (ON), BC Decker.
Ponder BA. Cancer genetics. Nature 411: 336-41, 2001.
Queiroga FL, Pérez-Alenza D, Silvan G, Peña L, Illera JC (2009) Positive correlation of steroid hormones and EGF in canine mammary cancer. J Steroid Biochem Mol Biol 115: 9-13.
Racaniello M. Il complesso della proteina chinasi DNA-PK: modulazione mediata dal peptide beta amiloide e coinvolgimento nella plasticità sinaptica. Facolta' di Medicina E Chirurgia, Università degli Studi Di Roma Tor Vergata. AA 2009-2010.
Rajan JV, Wang M, Marquis ST, Chodosh LA: Brca2 is coordinately regulated with Brca1 during proliferation and differentiation in mammary epithelial cells. Proc Natl Acad Sci USA 93: 13078–13083, 1996.
Rajan JV, Marquis ST, Gardner HP, Chodosh LA: Developmental expression of Brca2 colocalizes with Brca1 and is associated with proliferation and differentiation in multiple tissues. Dev Biol 184:385–401, 1997.
Rakha E.A., Reis-Filho J.S., Baehner F., Dabbs D.J., et al. Breast cancer prognostic classification in the molecular era: the role of histological grade. Breast Cancer Research, 2010, 12:207.
Rasotto R. Aspetti classificativi, epidemiologici, prognostici e profili di espressione proteica del Tumore Mammario del cane. Dipartimento di Sanitá Pubblica, Patologia Comparata e Igiene Veterinaria, Universitá Degli Studi Di Padova. AA 2010-2011.
Rehm S., Stanislaus D.J., Williams A.M. Estrous Cycle-Dependent Histology and Review of Sex Steroid Receptor Expression in Dog Reproductive Tissues and Mammary Gland and Associated Hormone Levels. Birth Defects Research (Part B), 2007, 80:233– 245.
Ressel L1, Puleio R, Loria GR, Vannozzi I, Millanta F, Caracappa S, Poli A. HER-2 expression in canine morphologically normal, hyperplastic and neoplastic mammary tissues and its correlation with the clinical outcome. Res Vet Sci. 2013 Apr;94(2):299-305.
Rivera P, Melin M, Biagi T, Fall T, Haggstrom J, Lindblad-Toh K, et al. Mammary tumor development in dogs is associated with BRCA1 and BRCA2. Cancer Res. 2009;69(22):8770–4. Rivera P, von Euler H. Molecular biological aspects on canine and human mammary
tumors. Vet Pathol.2011;48(1):132–46.
Romanelli G. Oncologia del cane e del gatto, Ed elsevier masson, 2007.
Rose, D.P., Gilhooly, E.M., Nixon, D.W., 2002. Adverse effects of obesity on breast cancer prognosis, and the biological actions of leptin (review). International Journal of Oncology 21, 1285.
Rosen E.M., Fan S., Pestell R.G., and Goldberg I.D.,“BRCA1 in hormone-responsive cancers,” Trends in Endocrinology and Metabolism,vol.14,no.8,pp.378–385,2003.
Rupert Allan Willis, The Spread of Tumours in the Human Body, Londra, Butterworths, 1934. Rutteman GR. Contraceptive steroids and the mammary gland: is there a hazard? Insight from
animal studies. Breast Cancer Research and Treatment 23, 29-41, 1992.
Santos M., Marcos R., Faustino A.M.R. Histological study of canine mammary gland during the oestrous cycle. Reprod Dom Anim, 2010, 45:146–154.
Sartin EA, Barnes S, Kwapien RP, Wolfe LG (1992) Estrogen and progesterone receptor status of mammary carcinomas and correlation with clinical outcome in dogs. American Journal of Veterinary Research, 53, 2196e2200.
Schafer KA, Kelly G, Schrader R, Griffith WC, Muggenburg BA, Tierney LA, Lechner JF, Janovitz EB, Hahn FF. A canine model of familial mammary gland neoplasia. Vet Pathol. 1998 May;35(3):168-77.
Schildkraut JM, Risch N, Thompson WD. Evaluating genetic association among ovarian, breast, and endometrial cancer: evidence for a breast/ovarian cancer relationship. Am J Hum Genet 45: 521-9, 1989.
Schneider R, Dorn CR, Taylor DO. Factors influencing canine mammary cancer development and postsurgical survival. J Nat Cancer Inst. 43(6):1249- 61. 1969, Dec.
Scully R, Chen J, Ochs RL, Keegan K, Hoekstra M, Feunteun J, Livingston DM. Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage. Cell 90: 425-35, 1997.
Selman P.J., Mol J.A., Rutteman G.R., Van Garderen E., e Rijnberk A. Progestin-induced growth hormone excess in the dog originates in the mammary gland. Endrocrinology, 134(1):287–292, 1994.
Shofer FS, Sonnenschein EG, Goldschmidt MH, Laster LL, Glickman LT. Histopathologic and dietary prognostic factors for canine mammary carcinoma. Breast Cancer Res Treat 13(1):49-60, 1989.
Slatter D. Trattato di chirurgia dei piccoli animali; 2005, ed. Antonio Delfino.
Sorenmo KU, Shofer FS, Goldschmidt MH. Effect of spaying and timing of spaying on survival of dogs with mammary carcinoma. J Vet Intern Med 14:266-270 (2000).
Sorenmo KU. Canine mammary gland tumors. Vet Clin Small Animal, 33:573-596, 2003. Sorenmo KU, Kristiansen VM, Cofone MA, Shofer FS, Breen AM, Langeland M, et al: Canine
mammary gland tumours; a histological continuum from benign to malignant; clinical and histopathological evidence. Vet Comp Oncol 7:162-72, 2009.
Sorenmo K.U., Rasotto R., Zappulli V., Goldschimdt M.H. The development, anatomy, histology, lymphatic drainage, clinical features and cell differentiation markers of canine mammary gland neoplasms. Vet. Pathol. 2011, Jan;48(1):85–97.
Starita LM, Parvin JD. The multiple nuclear functions of BRCA1: transcription, ubiquitination and DNA repair. Curr Opin Cell Biol. 2003; 15(3): 345-50.
Stovring M., Moe L., e Glattre E.. A population based case-control study of canine mammary tumors and clinical use of medroxyprogesterone acetate. APMIS, 105(8):590–596, 1997.
Susanne Liederer. Canine And Human Breast Cancer - A Comparative Analysis. University of Veterinary Medicine Vienna. 2011.
Szabo CI, Wagner LA, Francisco LV, Roach JC, Argonza R, King M, Ostrander EA (1996) Human, canine and murine BRCA1 genes: sequence comparison among species. Hum Mol Genet 5(9):1289– 1298.
Tavtigian SV, Simard J, Rommens J, Couch F, Shattuck-Eidens D, Neuhausen S, Merajver S, Thorlacius S, Offit K, Stoppa-Lyonnet D, Belanger C, Bell R, Berry S, Bogden R, Chen Q, Davis T, Dumont M, Frye C, et al. The complete BRCA2 gene and mutations in chromosome 13q-linked kindreds. Nat Genet 12: 333-7, 1996.
Taylor G.N., Shabestari L., Williams J., Mays C.W., Angus W., e McFarland S.. Mammary neoplasia in a closed beagle colony. Cancer Res., 36:2740–2743, 1976.
Tibiletti, M.G. (2012). Identificazione e gestione delle donne ad alto rischio per carcinoma ovarico e mammella.
Van Garderen E., De Wit M., Voorhout W.F, Rutteman G.R, Mol J.A., Nederbragt H., e Misdorp W. Expression of growth hormone in canine mammary tissue and mammary tumors. Amer. J. Pathol., 150(3):1037– 1047, 1997.
Venkitaraman AR. Cancer susceptibility and the functions of BRCA1 and BRCA2. Cell 108: 171-82, 2002.
Von Euler H. Tumours of the mammary glands. BSAVA Manual of Canine and Feline Oncology, J. Dobson and Lascelles, Eds., chapter 16, pp. 237–247, BSAVA, 3rd edition, 2011. Wang SC, Shao R, Pao AY, Zhang S, Hung MC, Su LK. Inhibition of cancer cell growth by
BRCA2. Cancer Res 62: 1311-4, 2002.
Wang Y, Cortez D, Yazdi P, Neff N, Elledge SJ, Qin J. BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures. Genes Dev. 2000; 14(8): 927-39.
Warner M.R. Age incidence and site distribution of mammary dysplasia in young beagle bitches. J. Natl. Cancer Inst., 57:57–61, 1976.
Watson C.J., Khaled W.T. Mammary Development in the Embryo and Adult: a Journey of Morphogenesis and Commitment. Development, 2008, 135:995–1003.
Weinberg, R.A., 1996. How cancer arises. Scientific American 275, 62-70.
Weinstein, I.B., Joe, A.K., 2006. Mechanisms of disease: Oncogene addiction--a rationale for molecular targeting in cancer therapy. Nature Clinical Practice Oncology 3, 448-457.
Welcsh, P.L, Owens, K.N. and King, M.C. (2000) Insights into the functions of BRCA1 and BRCA2. Trends in Genetics 16, 69-74.
Welcsh PL, King MC. BRCA1 and BRCA2 and the genetics of breast and ovarian cancer. Hum Mol Genet 10: 705-13, 2001.
Wiesen J.F., Young P., Werb Z., Cunha G.R. Signaling through the stromal epidermal growth factor receptor is necessary for mammary ductal development. Development, 126:335–344, 1999.
Withrow and MacEwen's Small Animal Clinical Oncology, 5th Edition, 2011.
Withrowe S.J., MacEwen E.G. SmallAnimalClinicalOncology. Saunders, Philadelphia, 2001. Wooster R, Neuhausen SL, Mangion J, Quirk Y, Ford D, Collins N, Nguyen K, Seal S, Tran T,
Averill D, Fields P, Marshall G, Narod S, Lenoir GM, Lynch H, Feunteun J, Devilee P, Cornelisse CJ, Menko FH, Daly PA, et al. Localization of a breast cancer susceptibility gene, BRCA2, to chromosome 13q12-13. Science 265: 2088-90, 1994.
Wu J, Lu L-Y, Yu X. The role of BRCA1 in DNA damage response. Protein & cell. 2010;1(2):117-123.
Wu LC, Wang ZW, Tsan JT, Spillman MA, Phung A, Xu XL, Yang MC, Hwang LY, Bowcock AM, Baer R. Identification of a RING protein that can interact in vivo with the BRCA1 gene product. Nat Genet. 1996; 14(4): 430-40.
Yamagami T, Kobayashi T, Takahashi K: Prognosis for canine malignant mammary tumors based on the TNM and histologic classification. J Vet Med Sci 58:1079–1083, 1996, Nov. Yarden RI, Brody LC. BRCA1 interacts with components of the histone deacetylase complex.
Proc Natl Acad Sci U S A. 1999; 96(9): 4983-8.
Yarden RI, Pardo-Reoyo S, Sgagias M, Cowan KH, Brody LC. BRCA1 regulates the G2/M checkpoint by activating Chk1 kinase upon DNA damage. Nat Genet 30: 285-9, 2002.
Yoshikawa Y, Morimatsu M, Ochiai K, Nagano M, Yamane Y, Tomizawa N, et al. Analysis of genetic variations in the exon 27 region of the canine BRCA2 locus. J Vet Med Sci. 2005;67(10):1013–7.
Yoshikawa Y, Morimatsu M, Ochiai K, Nagano M, Yamane Y, Tomizawa N, et al. Insertion/deletion polymorphism in the BRCA2 nuclear localization signal. Biomed Res. 2005;26(3):109–16.
Yoshikawa Y, Ochiai K, Morimatsu M, Suzuki Y, Wada S, Taoda T, Iwai S, Chikazawa S, Orino K and Watanabe K (2012) Effects of the missense mutations in canine BRCA2 on BRC repeat 3 functions and comparative analyses between canine and human BRC repeat 3. PLoS One. 2012; 7(10): e45833.
Yoshikawa Y., Morimatsu M., Ochiai K., Ishiguro-Oonuma T., Wada S., Orino K., Watanabe K. Reduced canine BRCA2 expression levels in mammary gland tumors. BMC Vet Res. 2015 Jul 23;11:159.
Zatloukal J, Lorenzova F, et al. Breed and Age as Risk Factors for Canine Mammary Tumours. ACTA VET. BRNO. 2005;74:103-109.
Zhang H, Somasundaram K, Peng Y, Tian H, Zhang H, Bi D, Weber BL, ElDeiry WS. BRCA1 physically associates with p53 and stimulates its transcriptional activity. Oncogene 1998; 16(13): 1713-21.
Zhong Q, Chen CF, Li S, Chen Y, Wang CC, Xiao J, Chen PL, Sharp ZD, Lee WH. “Association of BRCA1 with the hRad50-hMre11-p95 complex and the DNA damage response” Science 1999;; 285(5428): 747-50.
Zumkeller W. IGFs and IGFBPs: surrogate markers for diagnosis and surveillance of tumor growth; Mol. Pathol., 54(5):285–288, 2001.
