122
ABBREVIATIONS
ACV: ACycloVir
ADA: Adenosine DeAminase
AIRP: Autoimmune Infertility Related Protein
AML: Acute Myeloid Leukemia
AMPCP: α,β-Methylene adenosine 5’ diphosphate
AraC(MP): 1--D-ArabinofuranosideCytosine (MonoPhosphate) AraG(MP): 9- -D-ArabinofuranosylGuanine (MonoPhosphate) AraTMP: 1- -D -ArabinofuranosylThymine (MonoPhosphate) AZT(MP): 3’-azido-2’,3’-deoxy-thymidine (MonoPhosphate)
BSA: Bovine Serum Albumine
BPG: 2,3-BisPhosphoGlycerate
BvdU(MP) : (E)-5-(2-Bromovinyl)-2’-deoxyUridine (MonoPhosphate) CdA(MP): 2-Chloro-2’-deoxyAdenosine (MonoPhosphate)
cdN: cytosolic 5’ (3’)-deoxyriboNucleotidase CIAP: Calf Intestinal Alkaline Phosphatase CLL: Chronic Lymphocytic Leukemia cN-IA: Cytosolic 5’-Nucleotidase IA cN-IB: Cytosolic 5’-Nucleotidase IB cN-II: Cytosolic 5’-Nucleotidase II cN-III: Cytosolic 5’-Nucleotidase III
CNT: Concentrative Nucleoside-specific membrane Transport carriers cPPT: Central PolyPurine Tract
dCK: deoxyCitidine Kinase ddC(MP): 2’,3’-dideoxyCytidine (MonoPhosphate ) ddIno: 2’,3’-DideoxyInosine dFdCMP: 2’,3’-difluorodeoxycytidine monophosphate DFS: Disease-Free Survival dGK: deoxyGuanosine Kinase
DIGs: Detergent-Insoluble Glycolipid-enriched plasma membrane microdomains DMEM: Dulbecco's Modified Eagle's Medium
DMSO: DiMethylSulfOxyde
123 dNT-2: Mytochondrial 5’ (3’)-deoxyriboNucleotidase (d)NTP: (deoxy)Nucleotides TriPhosphate DPB-T (S)-1-[2’deoxy-3’,5’-O-(1-phosphono)benzylidene--D-threo- pentofuranosyl]-thymine d4TMP: 2',3'-Didehydro-3'-dideoxy-thymidine-5'-monophosphate DTT: DiThioTreitol 5-EddU 5-Ethynyl-2‘,3‘-dideoxyUridine EDTA: EthyleneDiamine Tetracetic Acid
e-N: Ecto 5’-Nucleotidase
ENT: Equilibrative Nucleoside-specific membrane Transport carriers FACS: Fluorescence-Activated Cell Sorter
F-araA(MP): 9- -D-arabinofuranosyl-2-fluoroadenine (MonoPhosphate) FBS: Foetal Bovine Serum
FdUMP: 5’-fluorodeoxyuridine monophosphate 5FdUrd: 5’-fluoro-2’-deoxyuridine
GFP: Green Fluorescent Protein GPI: Glycosyl PhosphatidylInosytil HAD: HaloAcid Dehalogenase HCL: Hairy Cell Leukemia
HEK: Human Embryonic Kidney (cell)
HGPRT: Hypoxanthine-Guanine PhosphoRibosyl Transferase HP-1: Heterochromatin Protein-1
HR: Homologous Recombination
IMPDH: 5’-Inosine MonoPhosphate DeHydrogenase IPTG: IsoPropyl--D-ThioGalactopyranoside IRES: Internal Ribosome Entry Site
KRAB: Krüppel-associated box
LDs: Lipid Droplets
LTR: Long Terminal Repeat
LV: Lentiviral Vector
mdN: Mitochondrial 5’(3’)-deoxyNucleotidase
MMS: Methyl MethaneSulfonate
MOI: Multiplicity Of Infection
124
NA: Nucleoside Analog
NAPDD: Nucleotidase Associated Pervasive Developmental Disorder NEB: New England Biolab (Inc.)
NDPK: Nucleoside DiPhosphate Kinases
Nef: Negative factor gene
NHA: Nonspherocytic Hemolytic Anemia NMPK: Nucleoside MonoPhosphate 5’-NT: 5’-Nucleotidase
NTP: Nucleotide TriPhosphate
OD: Optical Density
OS: Overall Survival
PAP: Prostatic Acid Phospahtase PCR: Polimerase Chain Reaction
PEI: PolyEthylenImine
PHT: PhosphoTransferase
pI: Isoelectric Point
PMN: PolyMorphoNuclear (leukocyte) PNP: Purine Nucleoside Phosphorylase
Pol: Polymerase
Prom: Promoter
PRPP: 5-PhosphoRybosyl 1-PyroPhosphate PSP: PhosphoSerine Phosphatase
RCL: Replication Competent Lentivirus Rev: Regulatory of virus gene
RNAi: RNA interference
SDS: Sodium Dodecyl-Sulphate SIN: Self Inactivating
Tat: Transactivation gene
TBE: Tris-Borate- EDTA (buffer) TK1/2: Thymidine Kinase 1/2 Vif: Virion infectivity factor Vpr: Viral protein R gene
Vpu: Virus protein U
125 WPRE: Woodchuck hepatisis virus Post-transcriptional Regulatory Element
X: Inside a protein primary structure means "any amino acid"
Xao: Xanthosine
XO: Xanthine Oxidase
ZMP: 5’-amino-4-imidazolecarboxamide-1--D-Ribofuranosyl monophosphate
126
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