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CONCLUSIONS

In this clinical experience it has been verified the feasibility of the Baby-EyePad tool in a population of preverbal patients, such as babies in their firsts days of life.

It can be asserted that the assessment with this method is very rapid, an important characteristic in a clinical setting, where several time constraints can be a limitation to more time consuming examinations, and when we have to work with patients which cannot warrant a prolonged attention. Nevertheless it keeps intact the scientific rigorous conditions used in laboratory FPL tests, which requires a random presentation of stimuli and a masked operator in respect to the content of each single trial.

We can affirm that babies give a good feedback to the instrument during the examination. Furthermore, when the settings of the tablet are preselected correctly for a given age-range, the procedure is very easy to perform and it can be taught to non-specialist clinicians. The instrument is handy and can be used with patients who are in an incubator.

In visual acuity tests, the Baby-EyePad is capable to reproduce, in a population of healthy term-newborns, the acuity values as described in literature, with no statistical difference compared with the mean of this reference population. The good correlation between test and re-test results demonstrates their reliability and reproducibility, an important characteristic for an instrument that has to be used in follow up of patients with visual dysfunctions.

This clinical experience was limited to the assessment of visual acuity, but it is important to note that the Baby-EyePad tool can contain several different visual tests, bringing together tasks for a complete evaluation of visual functions in a single tool which can be used rapidly and easily. Further development of the Baby-EyePad project will provide data for the other visual tasks or from different clinical populations.

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BIBLIOGRAPHY

[1] Sarnat HB, Sarnat MS. - Neonatal encephalopathy following fetal distress. A clinical and

electroencephalographic study. Arch Neurol. 1976 Oct;33(10):696-705.

[2] Richardson BS, Czikk MJ, daSilva O, Natale R. - The impact of labor at term on measures of

neonatal outcome. Am J Obstet Gynecol. 2005 Jan;192(1):219-26.

[3] Wayenberg JL, Vermeylen D, Damis E. - Définition de l’asphyxie à la naissance et incidence

des complications neurologiques et systémiques chez le nouveau-né à terme Arch Pediatr.

1998 Oct;5(10):1065-71. French

[4] Badawi N, Felix JF, Kurinczuk JJ, Dixon G, Watson L, Keogh JM, Valentine J, Stanley FJ. -

Cerebral palsy following term newborn encephalopathy: a population-based study. Dev Med

Child Neurol. 2005 May;47(5):293-8.

[5] Strijbis EM, Oudman I, van Essen P, MacLennan AH. - Cerebral palsy and the application of

the international criteria for acute intrapartum hypoxia. Obstet Gynecol. 2006

Jun;107(6):1357-65.

[6] Wang LW, Huang CC, Yeh TF. - Major brain lesions detected on sonographic screening of

apparently normal term neonates. Neuroradiology. 2004 May;46(5):368-73. Epub 2004 Apr 22.

[7] Estan J, Hope P. - Unilateral neonatal cerebral infarction in full term infants. Arch Dis Child Fetal Neonatal Ed. 1997 Mar;76(2):F88-93.

[8] Günther G, Junker R, Sträter R, Schobess R, Kurnik K, Heller C, Kosch A, Nowak-Göttl U. -

Symptomatic ischemic stroke in full-term neonates: role of acquired and genetic prothrombotic risk factors. Stroke. 2000 Oct;31(10):2437-41. Erratum in: Stroke 2001

(3)

[9] de Vries LS, Groenendaal F, Eken P, van Haastert IC, Rademaker KJ, Meiners LC. - Infarcts in

the vascular distribution of the middle cerebral artery in preterm and fullterm infants.

Neuropediatrics. 1997 Apr;28(2):88-96.

[10] Hanigan WC, Powell FC, Miller TC, Wright RM. - Symptomatic intracranial hemorrhage in

full-term infants. Childs Nerv Syst. 1995 Dec;11(12):698-707.

[11] Volpe JJ. - Intraventricular hemorrhage in the premature infant—current concepts. Part I. Ann Neurol. 1989 Feb;25(2):109-16.

[12] Osborn DA, Evans N, Kluckow M. - Hemodynamic and antecedent risk factors of early and

late periventricular/intraventricular hemorrhage in premature infants. Pediatrics. 2003

Jul;112(1 Pt 1):33-9.

[13] Hermoye L, Saint-Martin C, Cosnard G, Lee SK, Kim J, Nassogne MC, Menten R, Clapuyt P, Donohue PK, Hua K, Wakana S, Jiang H, van Zijl PC, Mori S. - Pediatric diffusion tensor imaging:

normal database and observation of the white matter maturation in early childhood.

Neuroimage. 2006 Jan 15;29(2):493-504. Epub 2005 Sep 27.

[14] Filippi L, Fiorini P, Daniotti M, Catarzi S, Savelli S, Fonda C, Bartalena L, Boldrini A, Giampietri M, Scaramuzzo R, Papoff P, Del Balzo F, Spalice A, la Marca G, Malvagia S, Della Bona ML, Donzelli G, Tinelli F, Cioni G, Pisano T, Falchi M, Guerrini R. - Safety and efficacy of topiramate in

neonates with hypoxic ischemic encephalopathy treated with hypothermia (NeoNATI). BMC

Pediatr. 2012 Sep 5;12:144. doi: 10.1186/1471-2431-12-144.

[15] Dogru M, Shirabe H, Nakamura M, Sekiya Y, Matsuno M, Taoka K, Nomura K, Yamamoto M. - Development of grating acuity in infants with Retinopathy of Prematurity. Acta Ophthalmol Scand. 1999 Feb;77(1):72-5.

[16] Luna B, Dobson V, Biglan AW. - Development of grating acuity in infants with regressed

stage 3 retinopathy of prematurity. Invest Ophthalmol Vis Sci. 1990 Oct; 31(10):2082-7.

[17] Good WV. - The spectrum of vision impairment caused by pediatric neurological injury. J AAPOS. 2007 Oct;11(5):424-5.

(4)

[18] Berman JI, Glass HC, Miller SP, Mukherjee P, Ferriero DM, Barkovich AJ, Vigneron DB, Henry RG. - Quantitative fiber tracking analysis of the optic radiation correlated with visual

performance in premature newborns. AJNR Am J Neuroradiol. 2009 Jan; 30(1):120-4. doi:

10.3174/ajnr.A1304. Epub 2008 Oct 2.

[19] Daum C, Kurtzberg D, Ruff H, Vaughan HJ. Preterm development of visual and auditory

orienting in very low birthweight infants. Pediatr Res 1980;14:432.

[20] Morante A, Dubowitz LM, Leven M, Dubowitz V. - The development of visual function in

normal and neurologically abnormal preterm and full-term infants. Dev Med Child Neurol. 1982

Dec; 24(6):771-84.

[21] Ipata AE, Cioni G, Boldrini A, Bottai P, van Hof-van Duin J. - Visual acuity of low- and

high-risk neonates and acuity development during the first year. Behav Brain Res. 1992 Jul

31;49(1):107-14.

[22] Ricci D, Cesarini L, Romeo DM, Gallini F, Serrao F, Groppo M, De Carli A, Cota F, Lepore D, Molle F, Ratiglia R, De Carolis MP, Mosca F, Romagnoli C, Guzzetta F, Cowan F, Ramenghi LA, Mercuri E. - Visual function at 35 and 40 weeks' postmenstrual age in low-risk preterm infants. Pediatrics. 2008 Dec;122(6):e1193-8. doi: 10.1542/peds.2008-1888.

[23] Ricci D, Cesarini L, Groppo M, De Carli A, Gallini F, Serrao F, Fumagalli M, Cowan F, Ramenghi LA, Anker S, Mercuri E, Mosca F. - Early assessment of visual function in full term newborns. Early Hum Dev. 2008 Feb;84(2):107-13. Epub 2007 May 21.

[24] Romeo DM, Ricci D, Serrao F, Gallini F, Olivieri G, Cota F, Romagnoli C, Mercuri E. - Visual

function assessment in late-preterm newborns. Early Hum Dev. 2012 May; 88(5):301-5. doi:

10.1016/j.earlhumdev.2011.08.024. Epub 2011 Sep 29.

[25] van Hof-van Duin J. - The development and study of visual acuity. Dev Med Child. Neurol. 1989 Aug;31(4):547-52. Review.

[26] Hoyt CS. - Visual function in the brain-damaged child. Eye (Lond). 2003 Apr;17(3):369-84. Review.

(5)

[27] Cavallini A, Fazzi E, Viviani V, Astori MG, Zaverio S, Bianchi PE, Lanzi G. - Visual acuity in the

first two years of life in healthy term newborns: an experience with the teller acuity cards.

Funct Neurol. 2002 Apr-Jun;17(2):87-92.

[28] Braddick O, Atkinson J, Wattam-Bell J. - Normal and anomalous development of visual

motion processing: motion coherence and 'dorsal-stream vulnerability'. Neuropsychologia.

2003;41(13):1769-84. Review.

[29] Mason AJ, Braddick OJ, Wattam-Bell J. - Motion coherence thresholds in infants--different

tasks identify at least two distinct motion systems. Vision Res. 2003 May;43(10):1149-57.

[30] Van Hof-Van Duin J. - Direction preference of optokinetic responses in monocularly tested

normal kittens and light deprived cats. Arch Ital Biol. 1978 Sep;116(3-4):471-7.

[31] Atkinson J. - Development of optokinetic nystagmus in the human infant and monkey

infant: An analogue to development in kittens. Dev Neurobiology of Vision NATO Advanced

Study Institutes Series Volume 27, 1979, pp 277-287.

[32] Atkinson J, Braddick O - Development of optokinetic nystagmus in infants: an indicator of

cortical binocularity? Acta Ophthalmol Suppl. 1983;157:27-35.

[33] Lewis TL, Maurer D, Chung JY, Holmes-Shannon R, Van Schaik CS. - The development of

symmetrical OKN in infants: quantification based on OKN acuity for nasalward versus temporalward motion. Vision Res. 2000;40(4):445-53.

[34] Morrone MC, Atkinson J, Cioni G, Braddick OJ, Fiorentini A. – Developmental changes in

optokinetic mechanisms in the absence of unilateral cortical control. Neuroreport. 1999 Sep

9;10(13):2723-9.

[35] Atkinson J, Hood B, Wattam-Bell J, Braddick O. - Changes in infants' ability to switch visual

attention in the first three months of life. Perception. 1992;21(5):643-53.

[36] Hikosaka O, Wurtz RH. - Visual and oculomotor functions of monkey substantia nigra pars

reticulata. II. Visual responses related to fixation of gaze. J Neurophysiol. 1983

(6)

[37] Hood B, Atkinson J. - Disengaging visual attention in the infant and adult. Infant Bahaviour and Development. 1993 Oct–Dec;16(4):405–422.

[38] Catford GV, Oliver A. Development of visual acuity. Arch Dis Child. 1973 Jan; 48(1):47-50.

[39] deVries LS, Eken P, Dubowitz LM The spectrum of leukomalacia using cranial ultrasound. Behav Brain Res. 1992 Jul 31;49(1):1-6.

[40] Dutton GN, Jacobson LK. - Cerebral visual impairment in children. Semin Neonatol. 2001 Dec;6(6):477-85. Review.

[41] Verhoeven JS, Sage CA, Leemans A, Van Hecke W, Callaert D, Peeters R, De Cock P, Lagae L, Sunaert S. - Construction of a stereotaxic DTI atlas with full diffusion tensor information for

studying white matter maturation from childhood to adolescence using tractography-based segmentations. Hum Brain Mapp. 2010 Mar;31(3):470-86. doi: 10.1002/hbm.20880.

[42] Bassi L, Ricci D, Volzone A, Allsop JM, Srinivasan L, Pai A, Ribes C, Ramenghi LA, Mercuri E, Mosca F, Edwards AD, Cowan FM, Rutherford MA, Counsell SJ. - Probabilistic diffusion

tractography of the optic radiations and visual function in preterm infants at term equivalent age. Brain. 2008 Feb;131(Pt2):573-82. doi: 10.1093/brain/awm327.

[43] Cioni G, Bertuccelli B, Boldrini A, Canapicchi R, Fazzi B, Guzzetta A, Mercuri E. - Correlation

between visual function, neurodevelopmental outcome, and magnetic resonance imaging findings in infants with periventricular leucomalacia. Arch Dis Child Fetal Neonatal Ed. 2000

Mar; 82(2):F134-40.

[44] Mercuri E, Atkinson J, Braddick O, Anker S, Nokes L, Cowan F, Rutherford M, Pennock J, Dubowitz L. - Visual function and perinatal focal cerebral infarction. Arch Dis Child Fetal Neonatal Ed. 1996 Sep; 75(2):F76-81.

[45] Maurer D, Lewis TL, Mondloch CJ. - Missing sights: consequences for visual cognitive

(7)

[46] Seghier ML, Lazeyras F, Zimine S, Saudan-Frei S, Safran AB, Huppi PS. - Visual recovery after

perinatal stroke evidenced by functional and diffusion MRI: case report. BMC Neurol. 2005 Sep

26;5:17.

[47] Cioni G, Fazzi B, Ipata AE, Canapicchi R, van Hof-van Duin J. - Correlation between cerebral

visual impairment and magnetic resonance imaging in children with neonatal encephalopathy.

Dev Med Child Neurol. 1996 Feb;38(2):120-32.

[48] Eken P, de Vries LS, van der Graaf Y, Meiners LC, van Nieuwenhuizen O. -

Haemorrhagic-ischaemic lesions of the neonatal brain: correlation between cerebral visual impairment, neurodevelopmental outcome and MRI in infancy. Dev Med Child Neurol. 1995

Jan;37(1):41-55.

[49] Mercuri E, Atkinson J, Braddick O, Anker S, Cowan F, Rutherford M, Pennock J, Dubowitz L. - Visual function in full-term infants with hypoxic-ischaemic encephalopathy. Neuropediatrics. 1997 Jun;28(3):155-61.

[50] Riddoch G. - Dissociation of visual perceptions due to occipital injury with especial

reference of movement. Brain. 1917

[51] Zeki S, Ffytche DH. - The Riddoch syndrome: insights into the neurobiology of conscious

vision. Brain. 1998 Jan;121 ( Pt 1):25-45. Review.

[52] Poppel E, Held R, Frost D. - Letter: Residual visual function after brain wounds involving

the central visual pathways in man. Nature. 1973 Jun 1;243(5405):295-6.

[53] Spear PD, Baumann TP. - Neurophysiological mechanisms of recovery from visual cortex

damage in cats: properties of lateral suprasylvian visual area neurons following behavioral recovery. Exp Brain Res. 1979 Mar 9;35(1):177-92.

[54] Kalil RE, Tong LL, Spear PD. - Thalamic projections to the lateral suprasylvian visual area in

(8)

[55] Tinelli F, Pei F, Guzzetta A, Bancale A, Mazzotti S, Baldassi S, Cioni G. - The assessment of

visual acuity in children with periventricular damage: a comparison of behavioural and electrophysiological techniques. Vision Res. 2008 May;48(10):1233-41. doi: 10.1016/j.visres.2008.02.009. Epub 2008 Apr 1.

[56] Chin KC, Taylor MJ, Menzies R, Whyte H. - Development of visual evoked potentials in

neonates. A study using light emitting diode goggles. Arch Dis Child. 1985 Dec; 60(12):1166-8.

[57] Aylward GP, Lazzara A, Meyer J. - Behavioral and neurological characteristics of a

hydranencephalic infant. Dev Med Child Neurol. 1978 Apr;20(2):211-7.

[58] Fantz RL et al. - Pattern perception in young infants. The Psychological Record. 1958 (8), 43-47.

[59] Dobson V, Teller DY, Lee CP, Wade B. - A behavioral method for efficient screening of visual

acuity in young infants I. Preliminary laboratory development. Invest Ophthalmol Vis Sci. 1978

Dec;17(12):1142-50.

[60] Allen D. - Visual acuity development in human infants up to 6 month of age. Vision Research. 1978;18(11):1469–1483

[61] Banks MS, Salapatek P. - Acuity and contrast sensitivity in 1-, 2-, and 3-month-old human

infants. Invest Ophthalmol Vis Sci. 1978 Apr;17(4):361-5.

[62] McDonald MA, Dobson V, Sebris SL, Baitch L, Varner D, Teller DY. - The acuity card

procedure: a rapid test of infant acuity. Invest Ophthalmol Vis Sci. 1985 Aug;26(8):1158-62.

[63] Mayer DL, Beiser AS, Warner AF, Pratt EM, Raye KN, Lang JM. - Monocular acuity norms for

the Teller Acuity Cards between ages one month and four years. Invest Ophthalmol Vis Sci.

1995 Mar;36(3):671-85.

[64] Hertz BG. - Acuity card testing of retarded children. Behav Brain Res. 1987 May;24(2):85-92.

(9)

[65] Hertz BG. - Use of the acuity card method to test retarded children in special schools. Child Care Health Dev. 1988 May-Jun;14(3):189-98.

[66] Hertz BG, Rosenberg J. - Acuity card testing of spastic children: preliminary results. J Pediatr Ophthalmol Strabismus. 1988 May-Jun;25(3):139-44.

[67] Hertz BG, Rosenberg J. - Effect of mental retardation and motor disability on testing with

visual acuity cards. Dev Med Child Neurol. 1992 Feb;34(2):115-22.

[68] Mash C, Dobson V. - Intraobserver reliability of the Teller Acuity Card procedure in infants

with perinatal complications. Optom Vis Sci. 2005 Sep;82(9):817-22.

[69] Dobson V, Quinn GE, Biglan AW, Tung B, Flynn JT, Palmer EA. - Acuity card assessment of

visual function in the cryotherapy for retinopathy of prematurity trial. Invest Ophthalmol Vis

Sci. 1990 Sep;31(9):1702-8.

[70] Dobson V, Quinn GE, Tung B, Palmer EA, Reynolds JD. - Comparison of recognition and

grating acuities in very-low-birth-weight children with and without retinal residua of retinopathy of prematurity. Invest Ophthalmol Vis Sci. 1995 Mar;36(3):692-702

[71] Harvey EM, Dobson V, Tung B, Quinn GE, Hardy RJ. - Interobserver agreement for grating

acuity and letter acuity assessment in 1- to 5.5-year-olds with severe retinopathy of prematurity. Invest Ophthalmol Vis Sci. 1999 Jun;40(7):1565-76.

[72] Kaernbach C. - Simple adaptive testing with the weighted up-down method. Percept Psychophys. 1991 Mar;49(3):227-9.

[73] Fazzi E, Cavallini A, Viviani V et al. - Lo sviluppo dell’acuità visiva nel primo anno di vita nel

nato a termine sano: un’esperienza con le Teller Acuity Cards. Riv Ital Pediatr, 1996, 22: 67-73.

[74] Ricci D, Romeo DM, Serrao F, Cesarini L, Gallini F, Cota F, Leone D, Zuppa AA, Romagnoli C, Cowan F, Mercuri E. - Application of a neonatal assessment of visual function in a population

(10)

[75] Yamamoto M, Brown AM. - Vision testing of premature infants using grating acuity cards. American Journal of Ophtalmology 1986 Aug;102:245-253

[76] Dobson V, Schwartz TL, Sandstrom DJ, Michel L. - Binocular visual acuity of neonates: the

acuity card procedure. Dev Med Child Neurol. 1987 Apr;29(2):199-206

[77] Vital-Durand F, Hullo A - La mesure de l’acuité visuelle du nourisson en six minutes : les

Cartes d’Acuité de Teller. J Fr Ophtalmol. 1989;12(3):221-5.

[78] Okereafor A, Allsop J, Counsell SJ, Fitzpatrick J, Azzopardi D, Rutherford MA, Cowan FM

Patterns of brain injury in neonates exposed to perinatal sentinel events. Pediatrics. 2008

May;121(5):906-14. doi: 10.1542/peds.2007-0770.

[79] Vijeya Ganesan, Fanella Kirkham- Stroke and cerebrovascular disease in childhood Mac Keith Press 2011 – for the International Child Neurology Association

[80] Good WV- Cortical Visual Impairment: New Directions. Optom Vis Sci. 2009 Jun;86(6):663-5. doi: 10.1097/OPX.0b013e3181a6176a.

[81] Braddick O, Atkinson J - Development of human visual function. Vision Res. 2011 Jul 1;51(13):1588-609. doi: 10.1016/j.visres.2011.02.018. Epub 2011 Feb 26.

[82] Brémond-Gignac D, Copin H, Lapillonne A, Milazzo S; European Network of Study and Research in EyeDevelopment. - Visual development in infants: physiological and pathological

mechanisms. Curr Opin Ophthalmol. 2011 Apr;22 Suppl:S1-8. doi: 10.1097/01.icu.0000397180.37316.5d.

[83] Birch EE, O'Connor AR - Preterm birth and visual development Semin Neonatol. 2001 Dec;6(6):487-97.

[84] Hoyt CS – Objective techniques of visual acuity assessment in infancy. Aust N Z J Ophthalmol. 1986 Aug;14(3):205-9.

(11)

[85] Ortibus EL, De Cock PP, Lagae LG. - Visual Perception in Preterm Children: What Are We

Currently Measuring? Pediatr Neurol. 2011 Jul;45(1):1-10. doi: 10.1016/j.pediatrneurol.2011.02.008.

[86] Hall HL, Courage ML, Adams RJ - The predictive utility of the Teller acuity cards for

assessing visual outcome in children with preterm birth and associated perinatal risks. Vision

Res. 2000;40(15):2067-76.

[87] Ricci D, Romeo DM, Serrao F, Gallini F, Leone D, Longo M, Albamonte E, Romeo MG, Mazzone D, Romagnoli C, Cowan F, Mercuri E - Early assessment of visual function in preterm

infants: How early is early? Early Hum Dev. 2010 Jan;86(1):29-33. doi: 10.1016/j.earlhumdev.2009.11.004. Epub 2010 Jan 6.

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