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Determination of blood Cd in subjects living near dismessed mines and active industrial sites

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Cadmium Symposium 2012 Sassari Italy

ICS

2012

International

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Cadmium Symposium 2012 Sassari Italy 50

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DETERMINATION OF BLOOD CD IN SUBJECTS LIVING NEAR DISMESSED MINES AND ACTIVE INDUSTRIAL SITES

Roberto Madeddu1,2, Paola Tolu1, Yolande Asara1, Cristiano Farace1, Giovanni Forte3, Beatrice Bocca3

1

Department of Biomedical Sciences-Histology, University of Sassari, Sassari, Italy

2

National Institute of Biostructures and Biosystems, Rome, Italy

3

Italian National Institute of Health, Rome, Italy

The environmental exposure to Cd in 265 subjects living in a South-Western area of Sardinia (Sulcis-Iglesiente) with a great history of mining activities and large industrial settings was assessed. Individuals living near the industrial plants had geometric means (GM) of blood Cd (0.79 µg/l) significantly higher than controls (0.47 µg/l) and than residents of the mining sites (0.54 µg/l). Demographic and lifestyle variables were also investigated and data showed that smoke and age are important variables to consider. In particular,

individuals aged 18-40 yrs, 41-60 yrs, and >60 yrs showed the following blood Cd GMs: 0.38, 0.55 and 0.76 µg/l. Smokers had blood Cd level (GM, 1.58 µg/l) much higher than ex-smokers (GM, 0.69 µg/l) and non-ex-smokers (GM, 0.43 µg/l). The population showed blood GM Cd (0.56 µg/l) similar to the GM (0.53 µg/l) calculated in the Middle-Eastern part of Sardinia (Nuoro province) and only slightly higher than that (0.32 µg/l) recorded in the North-Western part the island (Sassari province).

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