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Pelvic Floor Dysfunction

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G. Willy Davila, Gamal M. Ghoniem and Steven D. Wexner (Eds.)

Pelvic Floor Dysfunction

A Multidisciplinary Approach

With 178 Figures

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G. Willy Davila, MD Gamal M. Ghoniem, MD, FACS Chairman, Department Head, Section of Voiding Dysfunction,

of Gynecology; Head, Section Female Urology and Reconstruction of Urogynecology and Clinical Professor of Surgery/Urology, Reconstructive Pelvic Surgery NOVA Southeastern University Cleveland Clinic Florida Ohio State University and University of

Weston, FL, USA South Florida

Affiliate Associate Professor, University Cleveland Clinic Florida

of South Florida, USA Weston, FL, USA

Steven D. Wexner, MD, FACS, FRCS, FRCSED Chief of Staff, Cleveland Clinic Hospital 21st Century Oncology Chair in Colorectal

Surgery

Chairman, Department of Colorectal Surgery Cleveland Clinic Florida

Professor of Surgery, Ohio State University Health Sciences Center at Cleveland Clinic Foundation

Clinical Professor of Surgery, University of South Florida College of Medicine Research Professor, Charles E. Schmidt

College at Florida Atlantic University

A Catalogue record for this book is available from the British Library.

Library of Congress Control Number: 2005924370 ISBN-10: 1-85233-730-3 Printed on acid-free paper ISBN-13: 978-1-85233-730-8

© Springer-Verlag London Limited 2006

Apart from any fair dealing for the purposes of research or private study, or criticism or review, as permitted under the Copyright, Designs and Patents Act 1988, this publication may only be reproduced, stored or trans- mitted, in any form or by any means, with the prior permission in writing of the publishers, or in the case of reprographic reproduction in accordance with the terms of licences issued by the Copyright Licensing Agency.

Enquiries concerning reproduction outside those terms should be sent to the publishers. The use of registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant laws and regulations and therefore free for general use.

Product liability: The publisher can give no guarantee for information about drug dosage and application thereof contained in this book. In every individual case the respective user must check its accuracy by con- sulting other pharmaceutical literature.

Printed in the United States of America. (BS/MVY)

9 8 7 6 5 4 3 2 1

Springer Science+Business Media springeronline.com

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I dedicate this work to those who have been instrumental in the development of my urogynecologic career: Dr. Donald Ostergard for teaching me the basics and beyond, Dr.

Oscar Contreras Ortiz for encouraging me to become involved, and Dr. Harold Drutz for showing me how to achieve “the balance.” To these mentors and friends I am forever in debt, and no words can express my appreciation for their warmth and interest in my pro- fessional and personal growth. I attempt to emulate their efforts on a daily basis.

G. Willy Davila, MD

My work on this book is dedicated to the memory of the great men who influenced my life’s work, and who passed in December 2003. To the memory of my father, Mostafa Ghoniem and my mentor, Mohamed Al-Ghorab, to whom I will be eternally grateful for their love and support.

Gamal Ghoniem, MD

This book is dedicated to the most important people in my life – my family. To my parents, for having taught me by their example to succeed by hard work, honesty, and perseverance. Their love and guidance made it possible for me to have achieved my career. To my wife Nicolette, whose devotion to me and to our children and whose intel- lectual stimulation and love have made it possible for me to continue to be productive and innovative. To my children Wesley, Trevor, Marisa, and Gabriella, as it was precious time away from them that allowed me to produce these pages.

Steven D. Wexner, MD

The editors and authors express their gratitude to Ms. Kristin Dunn and Ms. Stacy Kopka for their exhaustive efforts in preparation of the manuscripts for publication; and Ross Papalardo and Beth Halasz for their superb medical illustration skills.

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Foreword

All the characteristics and driving force of The Cleveland Clinic are to be found in this book on pelvic floor function. The Cleveland Clinic is a group practice founded in 1921 on the principles of cooperation, collaboration, and collegiality. Its founders believed that many physicians working together will discover better solutions to medical problems than physicians working in isolation. They believed that the combination of disciplines, with their inherent differences in philosophy and skills, will produce a better outcome than might have evolved singularly.

The power of the collaborative approach is on full display in this book. The pelvic floor unites three separate organ systems. Before this time, each has been approached individually. Urologists, gynecologists, and colorectal surgeons are each trained in their own disciplines, and the pelvic floor is subsumed in these larger fields of study. When they combine their focus on the pelvic floor, they bring their unique perspectives and different approaches to a common goal: the relief of pelvic floor syndromes such as incontinence and pelvic organ prolapse.

The notion that three disciplines can combine for a better outcome than they would achieve singly, is a modern-day version of an old fable. The American poet John Godfrey Saxe (1816–1887) adapted that fable in his poem, “The Blind Men and the Elephant.” It tells the story of six blind wise men who encounter an elephant for the first time, and how they try to make sense of it by touch alone. The first blind man falls against the side of the elephant, and declares that the elephant is like a wall. The second man feels the tusk and concludes that anything so sharp is like a spear. The third man grabs the trunk and announces that the elephant is like a snake. The fourth man feels the knee and states that the elephant is like a tree. The fifth blind man touches the ear and decides that it is like a fan. The six man grabs the tail and decides it is a like a rope. Each wise man feels the elephant from his own small perspective and visualizes something different. As indi- viduals, they think they have the answer. But if they had combined their impressions, they would have reached a far different conclusion.

The practice of joining with colleagues to visualize a problem from your own per- spective and the group perspective, can lead to magnificent conclusions and interesting solutions. That is precisely what happens in this book. By combining the views of three different disciplines, which have furthered our knowledge of pelvic floor function, it offers a new and better approach to dysfunction. Medicine has advanced tremendously in the past half century, more specifically in the past two decades. The dominance of traditional specialties such as urology, gynecology, and general surgery has given way to an emphasis on subspecialties such as urogynecology, female urology, and colorectal surgery. This has allowed experts, such as the authors, to focus on a narrower field, and enjoy greater success than they might have if their concentration had been diluted by many broad interests. In this book, they are the personification of teamwork. Their char- acteristics of focus, innovation, collaboration, and dedication are the very qualities that will someday advance medicine far beyond anything we can imagine today.

By combining their expertise in this book, the authors have made a tremendous advance in the understanding of the pelvic floor and its dysfunction. They have raised vii

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viii Foreword

medicine to yet a higher level, and performed a service that will benefit patients with pelvic floor dysfunction for years to come.

Robert Kay, MD Vice Chairman, Board of Governors Chief of Staff The Cleveland Clinic Foundation Cleveland OH, USA

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Introduction

The aging of our population and arrival of the baby-boomers to advanced adulthood, with expectations for high quality of life, have led to a greater public awareness and help- seeking behavior regarding symptomatic dysfunction of the organs found within the pelvic cavity in women, the female pelvic floor. Women are increasingly less willing to simply accept incontinence or prolapse as a normal part of the aging process. New tech- nologies and a greater understanding of the pathophysiology underlying these dys- functions have provided us with a number of effective tools for treatment of these patients. Unfortunately, the traditional fragmentation of health care duties among spe- cialists has led to significant gaps in the treatment of pelvic floor dysfunction. The concept of the female pelvic floor as a single functional unit has not yet gained wide acceptance. Importantly, postgraduate training programs have not adapted their cur- ricula to meet the growing need to produce clinicians with an expertise in the manage- ment of the various aspects of pelvic floor dysfunction. Thus, there is not a sole clinician who can care for all of the problems that can develop within the pelvic floor. Under our current medical care environment, a multidisciplinary team approach will best serve the needs of symptomatic women. The need for such a team is gaining increasing degrees of acceptance at referral centers. Unfortunately, multiple barriers are in place to prevent such teams from forming and functioning efficiently.

There are currently efforts around the world to delineate training requirements for certification in Urogynecology/Female Pelvic Medicine/Reconstructive Pelvic Surgery (after training in Obstetrics and Gynecology) and Female Urology (after training in Urology). Colorectal surgeons and gastroenterologists have long had an interest in anatomic and functional problems of the lower intestinal tract. Nevertheless, clinicians caring for adjacent pelvic organ systems have yet to achieve a consensus regarding the importance and value of the evaluation and management of pelvic floor problems exis- tent on either side of an anatomic system. As a result, patients may undergo sequential operative procedures and/or achieve only limited quality-of-life improvement with therapy.

Realizing the above shortcomings and the frequent coexistence of pelvic floor dys- function symptoms among many patients referred for care, the Cleveland Clinic, at its various campuses, has developed a team approach to the care of such patients. Either within one Pelvic Floor Center, such as at our Fort Lauderdale/Weston, Florida campus or in very close proximity, such as in our Naples, Florida or Cleveland, Ohio campuses, patients are evaluated and treated by a team of clinicians with expertise in the various aspects of symptomatic dysfunction. After coordination of evaluation procedures, a treatment plan is designed. Whether care involves a combined surgical procedure or medical intervention, a patient’s medical care is streamlined and patients benefit from a global quality-of-life improvement. This text represents a compilation of the clinical approaches of the staff at Cleveland Clinic in the management of disorders involving the lower urinary, genital, and intestinal tracts. It should be a valuable reference for all cli- nicians involved in the care of women with symptomatic dysfunction of these systems.

It will be apparent to clinicians from various fields that there are remarkable similari- ties and analogies in terms of presenting symptoms, evaluation modalities, and treat- ment approaches. It is the hope of the authors that clinicians will begin to see the various organ systems as part of a combined unit. As such, recognizing the presence of symp- ix

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x Introduction

toms involving adjacent organ systems will encourage clinicians to recruit and involve other clinicians with expertise in addressing such symptoms in order to optimize the medical care being provided to a symptomatic patient. Our experience has demonstrated that improvements in quality of life and patient satisfaction can be greater when a com- prehensive, horizontally integrated approach is utilized, and we look forward to other centers adopting our model and philosophy of patient care.

G. Willy Davila, MD

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Contents

Foreword . . . . vii by Robert Kay

Introduction . . . . ix G. Willy Davila

SECTION I Concept of the Pelvic Floor as a Unit

1-1 Concept of the Pelvic Floor as a Unit

G. Willy Davila . . . . 3

SECTION II Epidemiology and Prevalence

2-1 Epidemiology of Non-Neurogenic Urinary Dysfunction

Usama M. Khater, Gassan Haddad, and Gamal M. Ghoniem . . . . 9 2-2 Bowel Dysfunction

James Doty and Jonathan E. Efron . . . . 15 2-3 Genital Prolapse, Urogenital Atrophy, and Sexual Dysfunction

Minda Neimark . . . . 19

SECTION III Evaluation

Introduction

Gamal M. Ghoniem . . . . 26 3-1 Primary Evaluation of the Pelvic Floor

Nathan Guerette, Dana R. Sands, and G. Willy Davila . . . . 27 3-2 Urodynamics

Gamal M. Ghoniem and Usama M. Khater . . . . 35 3-3 Imaging of the Genitourinary Tract in Females

M. Louis Moy and Sandip P. Vasavada . . . . 47 3-4 Anorectal Physiology

T. Cristina Sardinha and Dana R. Sands . . . . 51 3-5 Anorectal Ultrasound

Juan J. Nogueras . . . . 57 xi

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xii Contents

3-6 Neurologic Evaluation of the Pelvic Floor

Virgilio Salanga . . . . 63 3-7 Upper Gastrointestinal Evaluation Related to the Pelvic Floor

Gregory F. Bonner . . . . 67

SECTION IV Anatomic Correlates

Introduction

G. Willy Davila . . . . 70 4-1 Urologic Anatomic Correlates

Jonathan Jay . . . . 71 4-2 Genital Anatomic Correlates

Kevin J. Stepp and Matthew D. Barber . . . . 79 4-3 Colorectal Anatomic Correlates

James Doty and Eric G. Weiss . . . . 89

SECTION V Sexual Function

5-1 Female Sexual Dysfunction

Lawrence S. Hakim and Giovanna M. DaSilva . . . . 97

SECTION VI Incontinence Therapy

Introduction

Steven D. Wexner . . . . 108 6-1 Device Therapy for Stress Incontinence

Jennifer T. Pollak and G. Willy Davila . . . . 109 6-2 Medications for Stress Urinary Incontinence

G. Willy Davila . . . . 113 6-3 Sling/Tension-Free Vaginal Tape

Gamal M. Ghoniem and Usama M. Khater . . . . 115 6-4 Bulking Agents

Raymond R. Rackley and Ahmed Elazab . . . . 121 6-5 Retropubic Therapy for Stress Incontinence

Mark D. Walters . . . . 127 6-6 Laparoscopic Surgery for Urodynamic Stress Incontinence

Marie Fidela R. Paraiso . . . . 133 6-7 Other Therapies for Stress Urinary Incontinence

Tara L. Frenkl and Sandip P. Vasavada . . . . 137 6-8 Anal Sphincter Repair

Susan M. Cera and Steven D. Wexner . . . . 143 6-9 Fecal Diversion

Benjamin Person, James Doty, and Steven D. Wexner . . . . 151

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Contents xiii 6-10 ACYST, Secca, Sacral Nerve Stimulation, Artificial Bowel Sphincter, and

Stimulated Graciloplasty

Susan M. Cera and Eric G. Weiss . . . . 155 6-11 Case Presentation: Stress Urinary Incontinence/Fecal Incontinence

Daniel H. Biller and G. Willy Davila . . . . 163

SECTION VII Urgency/Frequency Syndromes Therapy

Introduction

Gamal M. Ghoniem . . . . 168 7-1 Overactive Bladder: Pharmacologic Therapy

Daniel H. Biller and G. Willy Davila . . . . 169 7-2 Sacral Nerve Stimulation

Joanna M. Togami and Gamal M. Ghoniem . . . . 175 7-3 Surgical Management of the Overactive Bladder: Evacuation Disorders

Raymond R. Rackley and Joseph Abdelmalak . . . . 181 7-4 Irritable Bowel Syndrome

Ronnie R. Pimentel . . . . 187 7-5 Irritable Bowel-Anismus

Wael Solh and Eric G. Weiss . . . . 189

SECTION VIII Prolapse Syndromes Therapy

Introduction

G. Willy Davila . . . . 192 8-1 Vaginal Pessaries

Minda Neimark . . . . 193 8-2 Vaginal Vault Prolapse Surgery

G. Willy Davila . . . . 199 8-3 Anterior Vaginal Prolapse Repairs

Sandip P. Vasavada and Matthew D. Barber . . . . 207 8-4 Vaginal Enterocele Repairs

Andrew I. Sokol and Mark D. Walters . . . . 217 8-5 Vaginal Rectocele Repairs

Jennifer T. Pollak and G. Willy Davila . . . . 223 8-6 Rectal Prolapse Therapy

T. Cristina Sardinha and Steven D. Wexner . . . . 229 8-7 Rectoanal Intussusception, Solitary Rectal Ulcer, and Sigmoidoceles

Juan J. Nogueras and Susan M. Cera . . . . 233 8-8 Case Presentation: Prolapse

G. Willy Davila and Daniel H. Biller . . . . 237

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xiv Contents

SECTION IX Pain and Irritative Syndromes Therapy

Introduction

Gamal M. Ghoniem . . . . 242 9-1 Interstitial Cystitis-Painful Bladder Syndrome

Gamal M. Ghoniem and Usama M. Khater . . . . 243 9-2 Painful Conditions of the Urogenital Sinus

Nathan Guerette and G. Willy Davila . . . . 251 9-3 Anal Pain

Tracy L. Hull . . . . 257 9-4 Pain Localization and Control

Wagih W. Gobrial . . . . 259 9-5 Acupuncture for Pelvic Floor Dysfunction

Lawrence P. Frank . . . . 263

SECTION X Evacuation Disorders

Introduction

Steven D. Wexner . . . . 268 10-1 Conservative Management of Urinary Retention in Women

Tara L. Frenkl and Firouz Daneshgari . . . . 269 10-2 Surgical Management of Urinary Retention

Raymond R. Rackley and Tara L. Frenkl . . . . 275 10-3 Bladder Outlet Obstruction after Anti-Incontinence

Surgery/Urethrolysis

Gamal M. Ghoniem and Usama M. Khater . . . . 281 10-4 Conservative Management of Constipation

Gregory F. Bonner . . . . 285 10-5 Surgical Management of Constipation

Tracy L. Hull . . . . 289

SECTION XI Hormonal Influences on the Pelvic Floor

11-1 Hormonal Influences on the Pelvic Floor

G. Willy Davila . . . . 295

SECTION XII Physiotherapeutic Approaches

Introduction

G. Willy Davila . . . . 302 12-1 Kegel Exercises and Biofeedback

Dawn Vickers and G. Willy Davila . . . . 303

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Contents xv 12-2 Timed Voiding and Fluid Management

Marie Fidela R. Paraiso and George Abate . . . . 311 12-3 Bowel Retraining for Functional Disorders of the Colon, Rectum,

and Anus

Susan M. Cera and Jonathan E. Efron . . . . 315

SECTION XIII Surgical Therapy: Mututal and Combined Aspects

Introduction

G. Willy Davila . . . . 320 13-1 Vesico-Vaginal Fistula

Gamal M. Ghoniem and Usama M. Khater . . . . 321 13-2 Rectovaginal Fistula

Susan M. Cera and Juan J. Nogueras . . . . 325 13-3 Enterourinary Fistula

T. Cristina Sardinha, Samir M. Yebara, and Steven D. Wexner . . . . 335 13-4 Management of Urinary Tract Injuries

Gamal M. Ghoniem and John C. Hairston . . . . 337 13-5 Combined Versus Sequential Reconstructive Surgeries

G. Willy Davila . . . . 341

SECTION XIV Severity Assessment

Introduction

Steven D. Wexner . . . . 346 14-1 Voiding Diary

Gamal M. Ghoniem and Usama M. Khater . . . . 347 14-2 Scoring Systems

Wael Solh and Steven D. Wexner . . . . 353 14-3 Quality-of-Life Assessment Tools

G. Willy Davila . . . . 359

Index . . . . 369

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Contributors

George Abate, DO

Department of Obstetrics and Gynecology, The Cleveland Clinic Foundation, Cleveland, OH, USA Joseph Abdelmalak, MD

Glickman Urological Institute, The Cleveland Clinic Foundation, Cleveland, OH, USA

Matthew D. Barber, MD, MHS Section of Urogynecology and

Reconstructive Pelvic Surgery, Department of Obstetrics and Gynecology, The Cleveland Clinic Foundation, Cleveland, OH, USA Daniel H. Biller MD

Section of Urogynecology and Reconstructive Pelvic Surgery, Department of Gynecology,

Cleveland Clinic Florida, Weston, FL, USA

Gregory F. Bonner, MD

Department of Gastroenterology, Cleveland Clinic Florida, Weston, FL, USA

Susan M. Cera, MD

Department of Colorectal Surgery, The Cleveland Clinic Foundation, Weston, FL, USA

Firouz Daneshgari, MD

Center for Female Pelvic Medicine and Reconstructive Surgery, Glickman Urological Institute, The Cleveland Clinic Foundation, Cleveland, OH, USA

Giovanna M. DaSilva, MD

Department of Colorectal Surgery, Cleveland Clinic Florida, Weston, FL, USA

G. Willy Davila, MD

Section of Urogynecology and Reconstructive Pelvic Surgery, Department of Gynecology, Cleveland Clinic Florida, Weston, FL, USA James Doty, MD

Department of Colorectal Surgery, Cleveland Clinic Florida, Naples, FL, USA

Jonathan E. Efron, MD, FACS, FASCRS Department of Colorectal Surgery,

Cleveland Clinic Florida, Naples, FL, USA

Ahmed Elazab, MD

Glickman Urological Institute, The Cleveland Clinic Foundation, Cleveland, OH, USA

Lawrence P. Frank, MD

Department of Anesthesiology, Cleveland Clinic Florida, Weston, FL, USA Tara L. Frenkl, MD, MPH

Glickman Urological Institute, The Cleveland Clinic Foundation, Cleveland, OH, USA

Gamal M. Ghoniem, MD, FACS

Section of Voiding Dysfunction, Female Urology and Reconstruction,

Department of Urology, Cleveland Clinic Florida, Weston, FL, USA Wagih W. Gobrial, MD

Section of Head Pain Management, Division of Anesthesiology, Cleveland Clinic Florida, Weston, FL, USA Nathan Guerette, MD

Section of Urogynecology and Reconstructive Pelvic Surgery, Department of Gynecology, Cleveland Clinic Florida, Weston, FL, USA

xvii

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xviii Contributors

Gassan Haddad, MD

Department of Internal Medicine, Cleveland Clinic Florida, Weston, FL, USA

John C. Hairston, MD

Section of Female Urology, Voiding Dysfunction and Pelvic

Reconstruction, Cleveland Clinic Florida, Department of Urology, Weston, FL, USA

Lawrence S. Hakim, MD, FACS Section of Sexual Medicine, Infertility

and Prosthetics, Department of Urology, Cleveland Clinic Florida, Weston, FL, USA

Tracy L. Hull, MD

Department of Colorectal Surgery, The Cleveland Clinic Foundation, Cleveland, OH, USA

Jonathan Jay, MD, FACS

Department of Urology, Cleveland Clinic Florida, Naples, FL, USA, USA Robert Kay, MD

Vice Chairman, Board of Governors, Chief of Staff, The Cleveland Clinic Foundation, Cleveland, OH, USA Usama M. Khater, MD

Section of Female Urology, Voiding Dysfunction and Pelvic

Reconstruction, Cleveland Clinic Florida, Department of Urology, Weston, FL, USA

M. Louis Moy, MD

Glickman Urological Institute, The Cleveland Clinic Foundation, Cleveland, OH, USA

Minda Neimark, MD

Section of Urogynecology and Reconstructive Pelvic Surgery, Department of Gynecology, Cleveland Clinic Florida, Weston, FL, USA Juan J. Nogueras, MD

Department of Colorectal Surgery, Cleveland Clinic Florida, Weston, FL, USA

Marie Fidela R. Paraiso, MD Department of Obstetrics and

Gynecology, Urological Institute and Women’s Health Center, Section of Urogynecology and Reconstructive Pelvic Surgery, The Cleveland Clinic Foundation, Cleveland, OH,

USA

Benjamin Person, MD

Department of Colorectal Surgery, Cleveland Clinic Florida, Weston, FL, USA

Ronnie R. Pimentel, MD, FACP, FACG Department of Gastroenterology,

Cleveland Clinic Florida, Weston, FL, USA

Jennifer T. Pollak, MD

Florida Center for Urogynecology, Hollywood, FL, USA

Raymond R. Rackley, MD

Glickman Urological Institute, The Cleveland Clinic Foundation, Cleveland, OH, USA

Virgilio Salanga, MD, MS Department of Neurology,

Cleveland Clinic Florida, Weston, FL, USA

Dana R. Sands, MD

Department of Colorectal Surgery, Cleveland Clinic Florida, Weston, FL, USA

T. Cristina Sardinha, MD

Department of Colorectal Surgery, Cleveland Clinic Florida, Weston, FL, USA

Andrew I. Sokol, MD

Section of Urogynecology and Reconstructive Pelvic Surgery, Department of Obstetrics and Gynecology, The Cleveland Clinic Foundation, Cleveland, OH, USA

Wael Solh, MD

Department of Colorectal Surgery, Cleveland Clinic Florida, Weston, FL, USA

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Contributors xix Kevin J. Stepp, MD

Section of Female Pelvic Medicine and Reconstructive Pelvic Surgery, Department of Obstetrics and Gynecology, The Cleveland Clinic Foundation, Cleveland, OH, USA Joanna M. Togami, MD

Section of Female Urology, Voiding Dysfunction and Pelvic

Reconstruction, Cleveland Clinic Florida, Department of Urology, Weston, FL, USA

Sandip P. Vasavada, MD

Section of Voiding Dysfunction and Female Urology, Glickman Urological Institute, The Cleveland Clinic Foundation, Cleveland, OH, USA Dawn Vickers, RN

Department of Gastroenterology, Cleveland Clinic Florida, Weston, FL, USA

Mark D. Walters, MD

Section of Female Pelvic Medicine and Reconstructive Pelvic Surgery, Department of Obstetrics and Gynecology, The Cleveland Clinic Foundation, Cleveland, OH, USA Eric G. Weiss, MD

Department of Colorectal Surgery, Cleveland Clinic Florida, Weston, FL, USA

Steven D. Wexner, MD, FACS, FRCS, FRCSED

Department of Colorectal Surgery, Cleveland Clinic Florida, Weston, FL, USA

Samir M. Yebara, MD

Department of Colorectal Surgery, Cleveland Clinic Florida, Weston, FL, USA

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