1) How should 99mTc sestamibi be administered when used for breast tumor imaging?
a. intramammary injection b. via indwelling catheter
c. via intravenous injection in the arm contralateral to involved breast
d. none of the above
2) What is the optimal scanning time for neoplasm when using 67Ga citrate?
a. 4 hours b. 6 hours c. 24 hours d. 48 hours
3) Lymphoscintigraphy is used to:
a. map lymphatic channels
b. determine drainage pathways from malignant neoplasms
c. identify the sentinel node d. all of the above
e. a and b only
4) Which of the following is true of67Ga citrate and 111In labeled leukocytes?
a. both require use of a medium energy collimator b. both can be used to effectively image neoplasms
and infections
c. both have 3 gamma peaks available for imaging d. all of the above
e. a and b only
5) 111In pentetreotide is a:
a. potassium analog b. monoclonal antibody c. somatostatin analog d. radiocolloid
6) A HAMA response occurs because:
a. a kit contains pyrogens
b. monoclonal antibodies are produced from mouse cells which the human body recognizes as a foreign protein c. a patient is allergic to 111In
d. monoclonal antibodies are produced from human cells that trigger an immune response in the patient
7) A dose of111In satumomab pendetide should be before injection.
a. shielded b. filtered c. assayed d. all of the above e. a and c only
8) 111In satumomab pendetide is used to image:
a. extrahepatic metastases from colorectal and ovarian cancer
b. breast tumors
c. neuroendocrine tumors d. lymphatic channels
9) Advantages of201Tl chloride over 67Ga citrate include:
a. much shorter half life
b. less uptake in inflammatory processes c. imaging may take place sooner d. all of the above
e. b and c only
10) It is possible to use 99mTc sestamibi for breast tumor imaging because there is no uptake of sestamibi in the normal breast.
a. true b. false
11) A monoclonal antibody is developed which displays cross-reaction. This means:
a. the antibody triggers an immune response in the patient
b. the antibody will bind antigens other than the one it was formed with
c. the antibody can be labeled with either 99mTc or 111In
d. none of the above
12) Examples of neuroendocrine tumor include:
a. pituitary adenoma b. small cell lung cancer c. neuroblastomas d. all of the above e. a and c only
13) Visualization of kidneys at 48 hours is on a scan using 111In pentetreotide and on a 67Ga citrate scan.
a. normal, abnormal b. abnormal, normal c. normal, normal d. abnormal, abnormal
14) 18FDG can be used to image tumors because the
glycolytic rate is higher in tumor than in normal tissues.
a. true b. false
15) Which of the following are true regarding 18FDG tumor imaging?
a. PET scanning is required
b. the patient should fast before the exam c. only brain tumors can be detected d. all of the above
e. all except c
16) On a Monday morning, a technologist learns that a patient needs to be scheduled for imaging with 67Ga citrate, and also a lower GI. If the ordering physician wishes that both exams be done within the week, how should these studies be scheduled?
a. lower GI on Monday morning, and 67Ga citrate on Monday afternoon
b. lower GI on Monday morning, and 67Ga citrate on Wednesday
c. 67Ga injection on Monday morning followed by imaging each day, lower GI at noon on Friday d. inject patient with 67Ga citrate on Monday morning,
send for lower GI, and then perform first imaging of gallium on Monday afternoon
17) Pheochromocytomas are imaged using:
a. 131I MIBG b. 131I NP-59
18) The use of PET imaging in oncology takes advantage of the differences between normal and neoplastic tissue.
a. structural b. metabolic c. density d. hormonal
19) Hodgkin’s disease is a type of:
a. lung cancer b. lymphoma c. AIDS d. lupus
20) Normal areas of uptake for 67Ga citrate include all of the following except:
a. intestinal mucosa b. parathyroid glands c. liver
d. epiphyses in pediatric patients
21) If a low energy collimator is using for imaging 67Ga, what will be the effect?
a. there is increased septal penetration b. poor spatial resolution
c. decreased sensitivity d. a and c
e. a and b
22) In general, the best radiopharmaceutical to use for a suspected abdominal abscess is:
a. 67Ga citrate
b. 111In labeled leukocytes c. 111In satumomab pendetide d. 111In octreotide
23) For imaging of inflammation or infection, leukocytes may be labeled with:
a. 111In oxine
b. 99mTc exametazime c. 67Ga citrate d. all of the above e. a and b only
24) The images in Figure 12.1 were obtained 24 hours following the injection of radiopharmaceutical to visualize infection in the right leg. The radio- pharmaceutical used was:
a. 99mTc sulfur colloid b. 111In labeled WBCs c. 67Ga citrate d. 99mTc exametazime Figure 12.1
25) If platelets are inadvertently labeled along with leukocytes during labeling with 111In oxine for imaging infection, the resulting scan may be:
a. false negative b. false positive
26) The collection of whole blood for leukocyte labeling should be performed:
a. with a small bore needle b. through an existing IV line c. using a heparinized syringe d. with a shielded syringe
27) To screen for infection in a severely leukopenic patient, the best choice of radiopharmaceutical would be:
a. 99mTc labeled WBCs b. 67Ga citrate
c. 111In labeled WBCs d. 99mTc sulfur colloid
28) Gravity sedimentation involves the settling of cells:
a. after centrifugation b. after time has passed
c. after the syringe or test tube is inverted d. after the sample has been placed over a magnet 29) The most appropriate dose to inject for imaging inflam-
mation with 111In labeled leukocytes is:
a. 0.5–1.0 mCi b. 2.0–4.0 mCi c. 5–10 mCi d. 6–8 mCi
30) 67Ga is often used with 3 phase bone scans to detect:
a. arthritis b. lung metastases c. osteomyelitis d. avascular necrosis e. rib fractures
31) On planar abdominal images obtained with 67Ga citrate, suspicious activity is noticed. Which technique would be the first choice for further investigation of that activity?
a. sequential SPECT scanning to observe change in the activity
b. subtract images obtained with 99mTc sulfur colloid c. hydrate the patient and encourage voiding before
reimaging
d. perform another exam with 111In leukocytes 32) Chewing gum between injection of18FDG and PET
scanning will have no effect on the resulting images.
a. True b. False
33) Why is it important to know if a patient has an inflam- matory condition before performing an 18FDG-PET scan?
a. 18FDG and certain anti-inflammatory medications cause severe reactions when used simultaneously.
b. 18FDG can exacerbate inflammatory conditions.
c. some inflammatory conditions cause areas of in- creased uptake of18FDG.
d. none of the above
34) Patient preparation for an 18FDG-PET scan includes:
a. NPO after midnight the evening before imaging b. fasting state of at least 4 hours prior to the exam c. avoiding intense physical activity the day before the
exam
d. all of the above e. b and c only
35) 18FDG is useful for imaging tumors because:
a. it is a glucose analog
b. there is an elevated rate of glycolysis in tumors c. it becomes trapped in tumor cells
d. all of the above e. a and c only
36) Which dose and route of administration is the best choice when performing a whole body PET scan with
18FDG and a dedicated PET scanner?
a. 2 mCi IV b. 2 mCi IM c. 10 mCi IV d. 10 mCi IM e. 30 mCI IV
37) Fill in the blank. High blood glucose levels may _____________18FDG uptake in tumors.
a. decrease b. increase
