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1.Come  cambia  l’epidemiologia  del  tumore  della  mammella  in  Italia.  I  risultati  del  progetto   IMPATTO   dei   programmi   di   screening   mammografico   IMPACT   Working   Group.   IMPACT   Working  Group,  Pacini  editore,  2011  

 

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3.   Roostaeian   J,   Crisera   C.   Current   options   in   breast   reconstruction   with   or   without   radiotherapy.  Curr  Opin  Obstet  Gynecol  Feb  2011;23(1):44e50.  

 

4.   Doing   More:   Trends   in   Breast   Cancer   Surgery,   2005   to   2011.   Lucas,   Donald   J.;  Sabino,   Jennifer;  Shriver,   Craig   D.;  Pawlik,   Timothy   M.;  Singh,   Devinder   P.;  Vertrees,   Amy   E.   The   American   Surgeon,   Volume   81,  Number   1,   January   2015,   pp.   74-­‐80(7)Southeastern   Surgical   Congress  

5.   Overgaard   M,   Jensen   MB,   Overgaard   J,   et   al.   Postoperative   ra-­‐   diotherapy   in   high-­‐risk   postmenopausal   breast-­‐cancer   patients   given   adjuvant   tamoxifen:   Danish   Breast   Cancer   Cooperative  Group  DBCG  82c  randomised  trial.  Lancet  1999;353:  1641–1648.  

6.  Ragaz  J,  Olivotto  IA,  Spinelli  JJ,  et  al.  Locoregional  radiation  therapy  in  patients  with  high-­‐ risk  breast  cancer  receiving  adjuvant  chemotherapy:  20-­‐year  results  of  the  British  Columbia   ran-­‐  domized  trial.  J  Natl  Cancer  Inst  2005;97:116–126.  

 

7.   Overgaard   M,   Hansen   PS,   Overgaard   J,   et   al.   Postoperative   radiotherapy   in   high-­‐risk   premenopausal   women   with   breast   cancer   who   receive   adjuvant   chemotherapy:   Danish   Breast  Cancer  Cooperative  Group  82b  trial.  N  Engl  J  Med  1997;337:  949–955.  

 

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10.  Early  Breast  Cancer  Trialists’  Collaborative  Group.  Effects  of  radiotherapy  and  surgery  in   early  breast  cancer:  An  overview  of  the  randomized  trials.  N  Engl  J  Med  1995;333:1444–1455.    

11.  Clarke  M,  Collins  R,  Darby  S,  et  al.  Effects  of  radiotherapy  and  of  differences  in  the  extent   of  surgery  for  early  breast  cancer  on  local  recurrence  and  15-­‐year  survival:  An  overview  of   the  rand-­‐  omised  trials.  Lancet  2005;366:2087–2106.  

 

12.   Strom   EA,   Woodward   WA,   Katz   A,   et   al.   Clinical   investigation:   Regional   nodal   failure   patterns  in  breast  cancer  patients  treated  with  mastectomy  without  radiotherapy.  Int  J  Radiat   Oncol  Biol  Phys  2005;63:1508–1513.  

13.   Recht   A,   Edge   SB,   Solin   LJ,   et   al.   Postmastectomy   radiother-­‐   apy:   Clinical   practice   guidelines  of  the  American  Society  of  Clinical  Oncology.  J  Clin  Oncol  2001;19:1539–1569.    

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14.  Galper  S,  Recht  A,  Silver  B,  et  al.  Factors  associated  with  re-­‐  gional  nodal  failure  in  patients   with   early   stage   breast   cancer   with   0–3   positive   axillary   nodes   following   tangential   irradiation  alone.  Int  J  Radiat  Oncol  Biol  Phys  1999;45:1157–1166.  

 

15.  Truong  PT,  Olivotto  IA,  Whelan  TJ,  Levine  M.  Clinical  practice  guidelines  for  the  care  and   treatment   of   breast   cancer:   16.   Locoregional   post-­‐mastectomy   radiotherapy.   CMAJ   2004;170:1263–73.  

 

16.  Recht  A,  Edge  SB,  Solin  LJ,  et  al.  Postmastectomy  radiotherapy:  clinical  practice  guidelines   of  the  American  Society  of  Clinical  Oncology.  J  Clin  Oncol  2001;19:1539–69.  

 

17.  Harris  JR,  Halpin-­‐Murphy  P,  McNeese  M,  Mendenhall  NP,  Morrow  M,  Robert  NJ.  Consensus   statement  on  postmastectomy  radiation  therapy.  Int  J  Radiat  Oncol  Biol  Phys  1999;44:989– 90.  

18.  Nielsen  HM,  Overgaard  M,  Grau  C,  Jensen  AR,  Overgaard  J.  Study  of  failure  pattern  among   high-­‐risk  breast  cancer  patients  with  or  without  postmastectomy  radiotherapy  in  addition  to   adjuvant   systemic   therapy:   long-­‐term   results   from   the   Danish   Breast   Cancer   Cooperative   Group  DBCG  82  b  and  c  randomized  studies.  J  Clin  Oncol  May  20  2006;24(15):2268e75.  

19.   Overgaard   M,   Nielsen   HM,   Overgaard   J.   Is   the   benefit   of   postmastectomy   irradiation   limited   to   patients   with   four   or   more   positive   nodes,   as   recommended   in   international   consensus   reports?   A   subgroup   analysis   of   the   DBCG   82   b&c   randomized   trials.   Radiother   Oncol  J  Eur  Soc  Ther  Radiol  Oncol  Mar  2007;82(3):247e53.  

 

20.   Recht   A,   Edge   SB,   Solin   LJ,   et   al.   Postmastectomy   radiother-­‐   apy:   Clinical   practice   guidelines  of  the  American  Society  of  Clinical  Oncology.  J  Clin  Oncol  2001;19:1539–1569.    

21.  Galper  S,  Recht  A,  Silver  B,  et  al.  Factors  associated  with  re-­‐  gional  nodal  failure  in  patients   with   early   stage   breast   cancer   with   0–3   positive   axillary   nodes   following   tangential   irradiation  alone.  Int  J  Radiat  Oncol  Biol  Phys  1999;45:1157–1166.  

   

22.  Sartor  CI.  Postmastectomy  radiotherapy  in  women  with  breast  cancer  metastatic  to  one  to   three  axillary  lymph  nodes.  Curr  Oncol  Rep  2001;3:497–505.  

 

23.   Pierce   LJ.   The   use   of   radiotherapy   after   mastectomy:   A   review   of   the   literature.   J   Clin   Oncol  2005;23:1706–1717.  

 

24.   Estrogen   Receptor,   Progesterone   Receptor,   HER-­‐2,   and   Response   to   Postmastectomy   Radiotherapy  in  High-­‐Risk  Breast  Cancer:  The  Danish  Breast  Cancer  Cooperative  Group  

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25.  McCready  DR,  Chapman  JA,  Hanna  WM,  Kahn  HJ,  Murray  D,  Fish  EB,  et  al.  Factors  affecting   distant  disease-­‐free  survival  for  primary  invasive  breast  cancer:  use  of  a  log-­‐normal  survival   model.  Ann  Surg  Oncol  2000;  7:  416-­‐26.  

 

26.  Trovo  M,  Durofil  E,  Polesel  J,  Roncadin  M,  Perin  T,  Mileto  M,  et  al.  Locoregional  failure  in   early-­‐stage   breast   cancer   patients   treated   with   radical   mastectomy   and   adjuvant   systemic  

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therapy:   Which   patients   benefit   from   postmastectomy   irradiation?   Int   J   Radiat   Oncol   Biol   Phys  2012;  83:  e153-­‐e157  

 

27.   Karlsson   P,   Cole   BF,   Chua   BH,   Price   KN,   Lindtner   J,   Collins   JP,   et   al.   Patterns   and   risk   factors  for  locoregional  failures  after  mastectomy  for  breast  cancer:  an  International  Breast   Cancer  Study  Group  report.  Ann  Oncol  2012;  23:  2852-­‐8.    

 

28.  Van  de  Steene  J,  Soete  G,  Storme  G.  Adjuvant  radiotherapy  for  breast  cancer  significantly   improves  overall  survival:  The  missing  link.  Radiother  Oncol  2000;55:263–272.  

 

29.  Ragaz  J,  Jackson  SM,  Plenderleith  IH,  et  al.  Can  adjuvant  radiotherapy  improve  the  overall   survival  of  breast  cancer  patients  in  the  presence  of  adjuvant  chemotherapy?  10-­‐yr  analysis  of   the   British   Columbia   randomized   trial.   (Abstr.)   Proc   Annu   Meet   Am   Soc   Clin   Oncol   1993;12:A40.  

 

30.  THE  SIGNIFICANCE  OF  EXTRACAPSULAR  EXTENSION  OF  AXILLARY  LYMPH  NODE  METASTASES  IN  EARLY-­‐ STAGE   BREAST   CANCER   STELLA   HETELEKIDIS,   M.D.,*†   STUART   J.   SCHNITT,   M.D.,§   BARBARA   SILVER,   B.A.,*   JUDITH  MANOLA,  M.S.,  BRUCE  A.  BORNSTEIN,  M.D.,*†  ASA  J.  NIXON,  M.D.,*‡  ABRAM  RECHT,  M.D.,*‡  REBECCA   GELMAN,  PH.D.,*  JAY  R.  HARRIS,  M.D.,*†  AND  JAMES  L.  CONNOLLY,  M.D.§  2000  Elsevier  Science  Inc.  

 

31.   Goldhirsch   A,   Wood   WC,   Coates   AS,   Gelber   RD,   Thurlimann   B,   Senn   HJ.   Strategies   for   subtypesedealing  with  the  diversity  of  breast  cancer:  highlights  of  the  St.  Gallen  International   Expert   Consensus   on   the   primary   therapy   of   early   breast   cancer   2011.   Ann   Oncol   Aug   2011;22(8):1736e47.  

 

32.  Hamamoto  Y,  Ohsumi  S,  Aogi  K,  Takashima  S,  Shinohara  S,  Nakajima  N,  et  al.  Identification   of   candidates   for   postmastectomy   radiotherapy   in   patients   with   pT3N0M0   breast   cancer.   Breast  Cancer  2013  July;20(3):218e22.  

 

33.   Karlsson   P,   Cole   BF,   Chua   BH,   Price   KN,   Lindtner   J,   Collins   JP,   et   al.   Patterns   and   risk   factors  for  locoregional  failures  after  mastectomy  for  breast  cancer:  an  International  Breast   Cancer  Study  Group  report.  Ann  Oncol  2012;  23:  2852-­‐8.  

 

34.   Hunt   KK,   Ballman   KV,   McCall   LM,   Boughey   JC,   Mittendorf   EA,   Cox   CE,   et   al.   Factors   associated  with  local-­‐regional  recurrence  after  a  negative  sentinel  node  dissection.  Ann  Surg   2012;  256:  428-­‐36.  

 

35.   Post-­‐mastectomy   radiotherapy   benefits   subgroups   of   breast   cancer   patients   with   T1-­‐2   tumor  and  1–3  axillary  lymph  node(s)  metastasis  

Yu-­‐Li   Su1,   Shan-­‐Hsuan   Li1,2,   Yen-­‐Yang   Chen1,   Hui-­‐Chun   Chen3,   Yen   Tang4,   Cheng-­‐Hua   Huang1,   Fong-­‐Fu   Chou2,5,   Shih-­‐Chung   Wu5,   Kun-­‐Ming   Rau1,2,6   Radiol   Oncol   2014;   48(3):   314-­‐322.  

 

36.   Recht   A,   Edge   SB,   Solin   LJ,   Robinson   DS,   Estabrook   A,   Fine   RE,   et   al.   Postmastectomy   radiotherapy:  clinical  practice  guidelines  of  the  American  Society  of  Clinical  Oncology.  J  Clin  

Oncol  2001;  19:  1539-­‐69.  

 

37.   Pierce   LJ.   Treatment   guidelines   and   technique   in   delivery   of   postmastectomy   radiotherapy   in   management   of   operable   breast   cancer.   J   Natl   Cancer   Inst   Monogr   2001;   30:117-­‐124.    

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38.  Kurtz  J  for  the  EUSOMA  Working  Party.  The  curative  role  of  radiotherapy  in  the  treatment   of  operable  breast  cancer.  Eur  J  Cancer  38:1961-­‐1974,  2002.  

 

39.   Truong   PT,   Olivotto   IA,   Whelan   TJ,   Levine   M,   for   the   Steering   Committee   on   Clinical   Practice  Guidelines  for  the  Care  and  Treatment  of  Breast  Cancer.  Clinical  practice  guidelines   for   the   care   and   treatment   of   breast   cancer:   16.   Locoregional   postmastectomy   radiotherapy.CMAJ2004;170:1263-­‐1273.  

40.  Kunkler  I,  Canney  P,  van  Tienhovan  G,  et  al.  Elucidating  the  role  of  chest  wall  irradiation  in   ‘‘intermediate-­‐risk’’  breast  cancer:  The  MRC/EORTC/SUPREMO  trial.  Clin  Oncol  2008;20:31– 34.  

   

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