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(1)

F E D E R I C A M A Z Z U C A

A Z I E N D A O S P E D A L I E R A S A N T ’ A N D R E A U N I V E R S I T À D I R O M A « S A P I E N Z A » F E D E R I C A . M A Z Z U C A @ U N I R O M A 1 . I T

(2)

Gastrointestinal – non colorectal

GASTRIC CANCER 1. FLOT4

2. JACOB

3. ATTRACTION 02 4. KEYNOTE 059

Biliary tract Cancer 1. Bilcap

2. Prodige 12- Accord 18 Hepatocellular Carcinoma 1. Reflect study

(3)

Gastric Cancer

(4)

Gastric cancer

(5)

OS in pp Population (predefined analysis)

(6)

OS – multivariate analysis

(7)

OS – prognostic impact of Histology

(8)

OS – subgroup analysis

(9)

Gastric cancer

(10)

JACOB

(11)

JACOB

(12)

Gastric cancer

(13)

ATTRACTION-02

(14)

ATTRACTION-02

(15)

Gastric cancer

(16)

KEYNOTE-059

(17)

KEYNOTE-059

(18)

KEYNOTE-059

(19)

KEYNOTE-059

(20)

BiliaryTract Cancer

(21)
(22)
(23)
(24)

Biliary Tract Cancer

PRODIGE 12-ACCORD 18

Aim: RFS, maintaining health-related quality of life (Hr-QoL)

(25)

Biliary Tract Cancer

(26)

Biliary Tract Cancer

(27)

Hepatocellular carcinoma

(28)

Hepatocellular carcinoma

(29)

REFLECT STUDY

(30)

REFLECT STUDY

(31)

The best of the year meets the first post Esmo:

CONCLUSIONS

Gastric Cancer

•negative results for adjuvant GEMOX

•but… YES for Xeloda

Biliary Tract Cancer

•Lenvatinib: it is really better than sorafenib?

Hepatocellular Carcinoma

Riferimenti

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