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O D E L L O P E R I L C U R R I C U L U M V I T A E

INFORMAZIONI PERSONALI

Nome

RENZO GUERRINI

Data di nascita 25/11/1956

Qualifica Professore ordinario di Neuropsichiatria Infantile

Amministrazione Università degli Studi di Firenze – AOU Meyer

Incarico attuale Direttore Unità Operativa Complessa Clinica di Neurologia Pediatrica- AOU MEYER (da 2006)

Direttore Scientifico IRCCS Stella Maris (da 2009)

Numero telefonico dell’ufficio +39 055 5662573

Fax dell’ufficio +39 055 5662329

E-mail istituzionale [email protected]

TITOLI DI STUDIO E PROFESSIONALI ED ESPERIENZE LAVORATIVE

Titolo di studio -Laurea in Medicina e Chirurgia, 1982, Università di Perugia;

Altri titoli di studio e professionali -Specializzazione in Neurologia, 1986, Università di Perugia;

-Specializzazione in Esplorazioni Funzionali del Sistema Nervoso, 1988, Università di Marsiglia;

-Specializzazione in Neuropsichiatria Infantile, 1991, Università di Pisa;

Esperienze professionali (incarichi

ricoperti) - Assistente/Ricercatore Neuropsichiatra Infantile IRCCS Stella Maris dal 1 Gennaio 1988;

- Attaché, Centre Saint Paul et Service de Pedopsychiatrie CHU, Marsiglia, 1988- 1989;

- Responsabile del Laboratorio di Neurofisiopatologia dell’IRCCS Stella Maris, INPE Università di Pisa dal 1994 e del Centro di Riferimento per l’Epilessia dal 1996;

- Titolare Cattedra di Neuroscienze Cliniche, King's College Medical School, University of London 1999-2001;

- Titolare Cattedra di Neurologia Pediatrica, Great Ormond Street Hospital for Children and Institute of Child Health, University College London 2001-2002;

- Professore Associato in Neuropsichiatria Infantile dall’Ottobre 2002, Dipartimento di Medicina della Procreazione e dell' Età Evolutiva, Università di Pisa e Direttore di Unità Operativa Complessa di Neuropsichiatria Infantile, IRCCS Fondazione Stella Maris-Università di Pisa, dal 1° Gennaio 2004;

Capacità linguistiche Inglese (eccellente); francese (eccellente)

Capacità nell’uso di tecnologie ottimo

Altro (partecipazione a convegni e seminari, pubblicazioni, collaborazioni a riviste, ecc. ed ogni altra informazione che il dirigente ritiene di dover pubblicare)

Attività Scientifica / di Ricerca

- Coordinatore della Ricerca in Neurofisiologia, Neurogenetica e Neurochimica - IRCCS Fondazione Stella Maris di Pisa dal 1993 al 2006;

- Coordinatore di ricerche finalizzate finanziate dal Ministero della Salute, Telethon, Fondazione Mariani, MIUR, Istituto Superiore di Sanità, Comunità Europea e per Enti Esteri;

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- Autore di oltre 300 pubblicazioni su riviste Nazionali e Internazionali di cui 220 su riviste con Impact Factor (Impact Factor totale > 880; H index 50), autore di 9 libri aventi come oggetto di trattazione l' Epilessia, le Malformazioni Cerebrali, i Disturbi del Movimento in età evolutiva. Ha svolto oltre 300 relazioni su invito a Congressi Nazionali ed Internazionali.

Le epilessie pediatriche e le alterazioni dello sviluppo cerebrale costituiscono il principale settore clinico di ricerca;

Membro dell'Editorial Board delle seguenti riviste:

_ Epilepsies (dal 1995);

_ Epilepsia: (1999-2003);

− Journal of Child Neurology (dal 1995);

− Epileptic Disorders (dal 1999),

− Seizure (sac 2001-2002; 2006-),

− Neuropediatrics (2001-),

− BMC Medical Genetics (2006-).

− Advances in Epilepic Disorders (2006-)

− Scientific Committee - Topics in Epilepsy (2009-) Associate Editor EPILEPSIA (2006-2009; 2009-) Membro di Commissioni Scientifiche e Referee per:

- General Medical Council, UK

- Institut National Santé e Recherche Medicale INSERM, France - Wellcome Trust

- Institute of Child Health

- The Harvard Medical School, Boston - The Cornell University, New York

- University of Birmingham

- Riken Brain Science Institute, Hirosawa (Japan)

Riconoscimenti Internazionali (Awards): Ambassador for Epilepsy, The International League Against Epilepsy (2003).

Attività con funzioni esecutive di Organismi Scientifici e Didattici Nazionali ed Internazionali:

- Membro eletto Consiglio Direttivo, Lega Italiana Contro l'Epilessia (dal 1996 al 2005);

- Trustee, The Fund for Epilepsy, Charitable Foundation (since 1999).

- Key Member, Commission of Pediatrics, International League Against Epilepsy (ILAE) (May 1997-November 2000);

- Chairman, The Commission on Pediatrics, ILAE (2001-2006);

- Task Force of Classification and Terminology, ILAE (1999-2001);

- Co-Director Master of Science Course in 'Epileptology' King's College - University of London (1999-2000);

- Chairman, subcommission on Neuropsychology in Children , The International League Against Epilepsy (1999-2000)

- Director, Epilepsy Summer course on: Epilepsy in children: neurobiological, clinical

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and therapeutic approach; International School of Neurological Sciences of Venice (July 11th-22nd 2004)

- Commission for guidelines of treatment of childhood epilepsy: World Health Organization (2003-2004);

- Member, Paediatric Epilepsy Expert Group at EMEA (European Medicines Agency (2009))

Prof. Renzo Guerrini

Full length articles in peer reviewed journals with impact factor.

Impact Factor = 881,02 (updated September 2009 /pubblicazione n° 220) 220. Guerrini R

Physiology of epilepsia partialis continua and subcortical mechanisms of status epilepticus Epilepsia, in press.

IF=3.733 219. Mei D, Marini C, Novara F, Dalla Bernardina B, Granata T, Fontana E, Parrini E, Ferrari AR, Murgia A, Zuffardi O, Guerrini R. Xp22.3 genomic deletions involving the CDKL5 gene in girls with early onset epileptic encephalopathy.

Epilepsia, in press

IF=3.733 218. La Marca G, Malvagia S , Filippi L, Luceri F, Moneti G, Guerrini R

A new rapid micro-method for the Phenobarbital assay from dried blood spot by LC-Tandem Mass Spectrometry

Epilepsia, 2009 Jul 20 [Epub ahead of print]

IF=3.73 217. Suls A, Mullen SA, Weber YG, Verhaert K, Ceulemans B, Guerrini R, Wuttke TV, Salvo- Vargas A, Deprez L, Claes LRF, Jordanova A, Berkovic SF, Lerche H, De Jonghe P,

Scheffer IE

Early onset absence epilepsy due to mutations in the glucose transporter GLUT1 Annals of Neurology, in press

IF=9.935 216. Filippi L, La Marca G, Fiorini P, Poggi C, Cavallaro G, Malvagia S, Pellegrini-Giampietro D, Guerrini R

Topiramate concentrations in neonates treated with prolonged whole body hypothermia for hypoxic ischaemic encephalopathy

Epilepsia, 2009 Sep 10. [Epub ahead of print]

IF=3.733 215. Ferland RJ, Guerrini R

Nodular heterotopia is built upon layers

Neurology, 2009 Sep 8;73(10):742-3. Epub 2009 Jul 22. No abstract available.

IF=7.043

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214. Cavicchi C, Malvagia S, la Marca G, Gasperini S, Donati MA, Zammarchi E, Guerrini R, Morrone A, Pasquini E.

Hypocitrullinemia in expanded newborn screening by LC-MS/MS is not a reliable marker for ornithine transcarbamylase deficiency.

J Pharm Biomed Anal. 2009 Jul 12;49(5):1292-5. Epub 2009 Mar 20.

IF=2.629

213. Caciotti A, Di Rocco M, Filocamo M, Grossi S, Traverso F, d'Azzo A, Cavicchi C, Messeri A, Guerrini R, Zammarchi E, Donati MA, Morrone A.

Type II sialidosis: review of the clinical spectrum and identification of a new splicing defect with chitotriosidase assessment in two patients.

J Neurol. 2009 Jul 1. [Epub ahead of print]

IF=2.536 212. La Marca G, Casetta B, Malvagia S, Guerrini R, Zammarchi E

New Strategy for the screening of Lysosomal Storage Disorders: the use of the online trapping- and-cleanup liquid Chromatography/Mass Spectrometry

Anal Chem. 2009 Jun 25. (Epub ahead of print)

IF=5.712

211. Marini C, Scheffer IE, Nabbout R, Mei D, Cox K, Dibbens LM, McMahon JM, Iona X, Carpintero RS, Elia M, Cilio MR, Specchio N, Giordano L, Striano P, Gennaro E, Cross JH, Kivity S, Neufeld MY, Afawi Z, Andermann E, Keene D, Dulac O, Zara F, Berkovic SF, Guerrini R, Mulley JC.

SCN1A duplications and deletions detected in Dravet syndrome: Implications for molecular diagnosis Epilepsia 2009 Mar 11. [Epub ahead of print]

IF=3.733

210. Guerrini R, Parrini E Neuronal migration disorders

Neurobiol Dis. 2009 Feb 23 [Epub ahead of print]

IF=4.852 209. Caciotti A, Donati MA, D'Azzo A, Salvioli R, Guerrini R, Zammarchi E, Morrone A

The potential action of galactose as a “chemical chaperone”: increase of beta galactosidase activity in fibroblasts from an adult GM1-gangliosidosis patient.

Eur J Paediatric Neurol. 2009 Mar; 13 (2): 160-4. Epub 2008 Jun 20

IF=1,421

208. Ferlazzo E, Adjien CK, Guerrini R, Calarese T, Crespel A, Elia M, Striano P, Gelisse P, Bramanti P, di Bella P, Genton P.

Lennox-Gastaut syndrome with late-onset and prominent reflex seizures in trisomy 21 patients.

Epilepsia. 2009 Jun;50(6):1587-95. Epub 2009 Jan 31.

IF=3.733

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207. Ferland RJ, Batiz LF, Neal J, Lian G, Bundock E, Lu J, Hsiao YC, Diamond R, Mei D, Banham AH, Brown PJ, Vanderburg CR, Joseph J, Hecht JL, Folkerth R, Guerrini R, Walsh CA, Rodriguez EM, Sheen VL.

Disruption of neural progenitors along the ventricular and subventricular zones in periventricular heterotopia.

Hum Mol Genet. 2009 Feb 1;18(3):497-516. Epub 2008 Nov 7.

IF=7.249 206. Arzimanoglou A, French J, Blume WT, Cross JH, Ernst JP, Feucht M, Genton P, Guerrini R, Kluger G, Pellock JM, Perucca E, Wheless JW

Lennox-Gastaut syndrome: a consensus approach on diagnosis, assessment, management, and trial methodology.

Lancet Neurol. 2009 Jan;8(1):82-93. Review.

IF=14.270 205. Cardoso C, Boys A, Parrini E, Mignon-Ravix C, McMahon JM, Khantane S, Bertini E, Pallesi E, Missirian C, Zuffardi O, Novara F, Villard L, Giglio S, Chabrol B, Slater HR, Moncla A, Scheffer IE and Guerrini R

Periventricular heterotopia, mental retardation and epilepsy associated with 5q14.3-q15 deletion

Neurology 2009 Mar 3;72(9):784-92. Epub 2008 Dec 10.

IF=7,043 204. Parrini E, Ferrari AR, Dorn T, Walsh CA, Guerrini R

Bilateral frontoparietal polymicrogyria, lennox-gastaut syndrome and GPR56 gene mutations Epilepsia. 2008 Nov 4. [Epub ahead of print]

IF=3.569

203. La Marca G, Malvagia S, Filippi L, Fiorini P, Innocenti M, Luceri F, Pieraccini G, Moneti G, Francese S, Romana Dani F, Guerrini R

Rapid Assay of Topiramate in Dried Blood Spots by a new Liquid Chromatography-Tandem Mass Spectrometric method

J Pharm Biomed Anal. 2008 Dec 15;48(5):1392-1396. Epub 2008 Sep 26.

IF=2.761

202. Cimaz R, Guerrini R.

Epilepsy in lupus.

Lupus 2008 Sep;17 (9):777-9. No Abstract available

IF=2.248

201. Carraresi L, Parini R, Filoni C, Caciotti A, Sersale G, Tomatsu S, Orlando C, Zammarchi E, Guerrini R, Donati MA, Morrone A.

GALNS gene expression profiling in Morquio A patients' fibroblasts.

Clin Chim Acta 2008 Nov;397 (1-2):72-6. Epub 2008 Jul 25

IF=2.601 200.Becherini F, Pisano T, Castagna M, Iannelli A, Guerrini R.

Progressive hemispheric shrinking in hemimegalencephaly: a possible role for seizure-related neuronal loss.

Dev Med Child Neurol. 2008 Jul;50 (7):553-7.

IF=2.433

199. Caciotti A, Donati MA, d'Azzo A, Salvioli R, Guerrini R, Zammarchi E, Morrone

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A.The potential action of galactose as a "chemical chaperone": Increase of beta galactosidase activity in fibroblasts from an adult GM1-gangliosidosis patient.

Eur J Paediatr Neurol. 2008 Jun 19. [Epub ahead of print]

IF=0.861

198. Filoni C, Caciotti A, Carraresi L, Donati MA, Mignani R, Parini R, Filocamo M, Soliani F, Simi L, Guerrini R, Zammarchi E, Morrone A.

Unbalanced GLA mRNAs ratio quantified by real-time PCR in Fabry patients' fibroblasts results in Fabry disease.

Eur J Hum Genet. 2008 Nov;16(11) :1311-7. Epub 2008 Jun 18

IF=4.003

197. Pramparo T, de Gregori M, Gimelli S, Ciccone R, Frondizi D, Liehr T, Pellacani S, Masi G, Brovedani P, Zuffardi O, Guerrini R.

A 7 Mb duplication at 22q13 in a girl with bipolar disorder and hippocampal malformation.

Am J Med Genet A. 2008 jul 1;146A (13):1754-60.

IF=2.440

196. Leventer RJ, Guerrini R, Dobyns WB.

Malformations of cortical development and epilepsy.

Dialogues Clin Neurosci. 2008;10 (1) :47-62. Review.

IF not available 195. Merello E, Swanson E, De Marco P, Akhter M, Striano P, Rossi A, Cama A,

Leventer RJ, Guerrini R, Capra V, Dobyns WB.

No major role for the EMX2 gene in schizencephaly.

Am J Med Genet A. 2008 May 1;146A (9):1142-50.

IF=2.440

194. Barba C, Guerrini R.

Unpleasant auditory illusions and related avoidance behaviour in a child.

Epileptic Disord. 2008 Mar;10 (1):35-8.

IF=0.919

193. Torniero C, Dalla Bernardina B, Novara F, Cerini R, Bonaglia C, Pramparo T, Ciccone R, Guerrini R, Zuffardi O.

Dysmorphic features, simplified gyral pattern and 7q11.23 duplication reciprocal to the Williams-Beuren deletion.

Eur J Hum Genet. 2008 Aug;16 (8): 880-7. Epub 2008 Mar 12.

IF=4.003

192. Pleasure SJ, Guerrini R.

Hypothalamic hamartomas and hedgehogs: not a laughing matter.

Neurology. 2008 Feb 19;70 (8):588-9. No abstract available.

IF=6.014

191. Mei D, Lewis R, Parrini E, Lazarou LP, Marini C, Pilz DT, Guerrini R.

High frequency of genomic deletions--and a duplication--in the LIS1 gene in lissencephaly: implications for molecular diagnosis.

J Med Genet. 2008 Jun;45 (6):355-61. Epub 2008 Feb 19.

IF=5.535

190. Guerrini R, Dobyns WB, Barkovich AJ.

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Abnormal development of the human cerebral cortex: genetics, functional consequences and treatment options.

Trends Neurosci. 2008 Mar;31(3):154-62. Epub 2008 Feb 8. Review.

IF=12.479 189. Guerrini R.

Subcortical structures and infantile spasms.

Dev Med Child Neurol. 2008 Feb;50 (2):87. No abstract available.

IF=2.433 188. Caciotti A, Donati MA, Adami A, Guerrini R, Zammarchi E, Morrone A.

Different genotypes in a large Italian family with recurrent hereditary fructose intolerance.

Eur J Gastroenterol Hepatol. 2008 Feb;20 (2):118-21.

IF=1.830 187. Van Bon BW, Koolen DA, Borgatti R, Magee A, Garcia-Minaur S, Rooms L, Reardon W, Zollino M, Bonaglia MC, De Gregori M, Novara F, Grasso R, Ciccone R, van

Duyvenvoorde HA, Aalbers AM, Guerrini R, Fazzi E, Nillesen WM, McCullough S, Kant SG, Marcelis CL, Pfundt R, de Leeuw N, Smeets D, Sistermans EA, Wit JM, Hamel BC, Brunner HG, Kooy F, Zuffardi O, de Vries BB.

Clinical and molecular characteristics of 1qter microdeletion syndrome:

delineating a critical region for corpus callosum agenesis/hypogenesis.

J Med Genet. 2008 Jun;45:346-54. Epub 2008 Jan 4.

IF=5.535 186. Kassaï B, Chiron C, Augier S, Cucherat M, Rey E, Gueyffier F, Guerrini R,

Vincent J, Dulac O, Pons G.

Severe myoclonic epilepsy in infancy: a systematic review and a meta-analysis of individual patient data.

Epilepsia. 2008 Feb;49 (2): 343-8. Epub 2007 Nov 19. Review.

IF=3.569 185. Guerrini R, Moro F, Kato M, Barkovich AJ, Shiihara T, McShane MA, Hurst J,

Loi M, Tohyama J, Norci V, Hayasaka K, Kang UJ, Das S, Dobyns WB.

Expansion of the first PolyA tract of ARX causes infantile spasms and status dystonicus.

Neurology. 2007 Jul ;69:427-33.

IF=6.014 184. Marini C, Guerrini R

The role of the nicotinic acetylcholine receptors in sleep-related epilepsy.

Biochem Pharmacol. 2007 Oct ;74:1308-14. Epub 2007 Jun 23. Review.

IF=4.006 183. Annesi F, Gambardella A, Michelucci R, Bianchi A, Marini C, Canevini MP,

Capovilla G, Elia M, Buti D, Chifari R, Striano P, Rocca FE, Castellotti B, Cali F, Labate A, Lepiane E, Besana D, Sofia V, Tabiadon G, Tortorella G, Vigliano P, Vignoli A, Beccaria F, Annesi G, Striano S, Aguglia U, Guerrini R, Quattrone A.

Mutational analysis of EFHC1 gene in Italian families with juvenile myoclonic epilepsy.

Epilepsia 2007 Sep;48:1686-90. Epub 2007 Jul 18.

IF=3.569

182. Everett K, Chioza B, Aicardi J, Aschauer H, Brouwer O, Callenbach P, Covanis A, Dooley J, Dulac O, Durner M, Eeg-Olofsson O, Feucht M, Friis M, Guerrini R, Heils A, Kjeldsen M, Nabbout R, Sander T, Wirrell E, McKeigue P, Robinson R, Taske N, Gardiner M.

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Linkage and mutational analysis of CLCN2 in childhood absence epilepsy.

Epilepsy Res. 2007 Jun 17; [Epub ahead of print]

IF=2.8 181. Marini C, Mei D, Temudo T, Ferrari AR, Buti D, Dravet C, Dias AI, Moreira A, Calado E, Seri S, Neville B, Narbona J, Reid E, Michelucci R, Sicca F, Cross HJ, Guerrini R.

Idiopathic Epilepsies with Seizures Precipitated by Fever and SCN1A Abnormalities.

Epilepsia. 2007 Jun 11; [Epub ahead of print]

IF=3.3 180. Sisodiya S, Cross JH, Blumcke I, Chadwick D, Craig J, Crino PB, Debenham P, Delanty N,

Elmslie F, Gardiner M, Golden J, Goldstein D, Greenberg DA, Guerrini R, Hanna M, Harris J, Harrison P, Johnson MR, Kirov G, Kullman DM, Makoff A, Marini C, Nabbout R, Nashef L, Noebels JL, Ottman R, Pirmohamed M, Pitkanen A, Scheffer I, Shorvon S, Sills G, Wood N, Zuberi S.

Genetics of epilepsy : Epilepsy Research Foundation workshop report.

Epileptic Disord. 2007 194-236.

IF=1.1

179. Trenite DG, French JA, Hirsch E, Macher JP, Meyer BU, Grosse PA, Abou-Khalil BW, Rosenfeld WE, van Gerven J, Novak GP, Parmeggiani L, Schmidt B, Gibson D, Guerrini R.

Evaluation of carisbamate, a novel antiepileptic drug, in photosensitive patients: an exploratory, placebo-controlled study.

Epilepsy Res. 2007:193-200. Epub 2007 Apr 19.

IF=2.8 178. Co JP, Elia M, Engel J Jr, Guerrini R, Mizrahi EM, Moshe SL, Plouin P.

Proposal of an algorithm for diagnosis and treatment of neonatal seizures in developing countries.

Epilepsia. 2007:1158-64. Epub 2007 Apr 18. IF=3.3

177. Guzzetta A, Bonanni P, Biagi L, Tosetti M, Montanaro D, Guerrini R, Cioni G.

Reorganisation of the somatosensory system after early brain damage.

Clin Neurophysiol. 2007 :1110-21. Epub 2007 Mar 23. IF=2.5

176. Striano P, Mancardi MM, Biancheri R, Madia F, Gennaro E, Paravidino R, Beccaria F, Capovilla G, Bernardina BD, Darra F, Elia M, Giordano L, Gobbi G, Granata T, Ragona F, Guerrini R, Marini C, Mei D, Longaretti F, Romeo A, Siri L, Specchio N, Vigevano F, Striano S, Tortora F, Rossi A, Minetti C, Dravet C, Gaggero R, Zara F.

Brain MRI findings in severe myoclonic epilepsy in infancy and genotype-phenotype correlations.

Epilepsia. Epub 2007 Mar 22.

IF=3.3

175. Mei D, Parrini E, Pasqualetti M, Tortorella G, Franzoni E, Giussani U, Marini C, Migliarini S, Guerrini R.

Multiplex ligation-dependent probe amplification detects DCX gene deletions in band heterotopia.

Neurology. 2007 :446-50. IF=5.9

174. Everett KV, Chioza B, Aicardi J, Aschauer H, Brouwer O, Callenbach P, Covanis A, Dulac O, Eeg- Olofsson O, Feucht M, Friis M, Goutieres F, Guerrini R, Heils A, Kjeldsen M, Lehesjoki AE, Makoff A, Nabbout R, Olsson I, Sander T, Siren A, McKeigue P, Robinson R, Taske N, Rees M, Gardiner M.

Linkage and association analysis of CACNG3 in childhood absence epilepsy.

Eur J Hum Genet. 2007 :463-72. Epub 2007 Jan 31. IF=2.7

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173. Torniero C, Bernardina BD, Novara F, Vetro A, Ricca I, Darra F, Pramparo T, Guerrini R, Zuffardi O.

Cortical dysplasia of the left temporal lobe might explain severe

expressive-language delay in patients with duplication of the Williams-Beuren locus.

Eur J Hum Genet. 2007;15:62-7. IF=2.7

172. Toldo I, Calderone M, Boniver C, Dravet C, Guerrini R, Laverda AM.

Hemiconvulsion-hemiplegia-epilepsy syndrome: Early magnetic resonance imaging findings and neuroradiological follow-up.

Brain Dev. 2007;29:109-11. IF=1.3

171. Chilosi AM, Brovedani P, Moscatelli M, Bonanni P, Guerrini R.

Neuropsychological findings in idiopathic occipital lobe epilepsies.

Epilepsia. 2006 Nov;47 Suppl 2:76-8. IF=3.3

170. Marini C, Mei D, Helen Cross J, Guerrini R.

Mosaic SCN1A mutation in familial severe myoclonic epilepsy of infancy.

Epilepsia. 2006;47:1737-40. IF=3.3

169. Gardella E, Tinuper P, Marini C, Guerrini R, Parrini E, Bisulli F, Liguori R, Montagna P, Lugaresi E.

Autosomal dominant early-onset cortical myoclonus, photic-induced myoclonus, and epilepsy in a large pedigree.

Epilepsia. 2006;47:1643-9. IF=3.3

168. Mancardi M, Striano P, Gennaro E, Madia F, Paravidino R, Scapolan S, Dalla Bernardina B, Bertini E, Bianchi A, Capovilla G, Darra F, Elia M, Freri E, Gobbi G, Granata T, Guerrini R, Pantaleoni C, Parmeggiani A, Romeo A, Santucci M, Vecchi M, Veggiotti P, Vigevano F, Pistorio A, Gaggero R, Zara F.

Familial occurrence of febrile seizures and epilepsy in severe myoclonic epilepsy of infancy (SMEI) patients with SCN1A mutations.

Epilepsia. 2006;47:1629-35. IF=3.3

167. Durner M, Gorroochurn P, Marini C, Guerrini R.

Can we increase the likelihood of success for future association studies in epilepsy?

Epilepsia. 2006;47:1617-21 IF=3.3

166. Robin NH, Taylor CJ, McDonald-McGinn DM, Zackai EH, Bingham P, Collins KJ, Earl D, Gill D, Granata T, Guerrini R, Katz N, Kimonis V, Lin JP, Lynch DR,

Mohammed SN, Massey RF, McDonald M, Rogers RC, Splitt M, Stevens CA, Tischkowitz MD, Stoodley N, Leventer RJ, Pilz DT, Dobyns WB.

Polymicrogyria and deletion 22q11.2 syndrome: window to the etiology of a common cortical malformation.

Am J Med Genet A. 2006;140:2416-25. IF=3.6

165. Walker RH, Danek A, Dobson-Stone C, Guerrini R, Jung HH, Lafontaine AL, Rampoldi L, Tison F, Andermann E.

Developments in neuroacanthocytosis: expanding the spectrum of choreatic syndromes.

Mov Disord. 2006;21:1794-805. IF=3.0

164. Moro F, Pisano T, Bernardina BD, Polli R, Murgia A, Zoccante L, Darra F, Battaglia A, Pramparo T, Zuffardi O, Guerrini R.

Periventricular heterotopia in fragile X syndrome.

Neurology. 2006 22;67:713-5. IF=5.9

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163. Aridon P, Marini C, Di Resta C, Brilli E, De Fusco M, Politi F, Parrini E, Manfredi I, Pisano T, Pruna D, Curia G, Cianchetti C, Pasqualetti M, Becchetti A, Guerrini R, Casari G.

Increased sensitivity of the neuronal nicotinic receptor alpha 2 subunit causes familial epilepsy with nocturnal wandering and ictal fear.

Am J Hum Genet. 2006;79:342-50. IF=12.3

162. Cross JH, Jayakar P, Nordli D, Delalande O, Duchowny M, Wieser HG, Guerrini R, Mathern GW; International League against Epilepsy, Subcommission for

Paediatric Epilepsy Surgery; Commissions of Neurosurgery and Paediatrics.

Proposed criteria for referral and evaluation of children for epilepsy surgery:

recommendations of the Subcommission for Pediatric Epilepsy Surgery.

Epilepsia. 2006;47:952-9. IF=3.3

161. Guerrini R, Marini C.

Genetic malformations of cortical development.

Exp Brain Res. 2006;173:322-33. IF=2.3

160. Parrini E, Ramazzotti A, Dobyns WB, Mei D, Moro F, Veggiotti P, Marini C, Brilstra EH, Dalla Bernardina B, Goodwin L, Bodell A, Jones MC, Nangeroni M, Palmeri S, Said E, Sander JW, Striano P, Takahashi Y, Van Maldergem L, Leopardi, G, Wright M, Walsh CA, Guerrini R.

Periventricular heterotopia: phenotypic heterogeneity and correlation with Filamin A mutations.

Brain. 2006;129:1892-906. IF=8.2

159. Guerrini R.

Valproate as a mainstay of therapy for pediatric epilepsy.

Paediatr Drugs. 2006;8:113-29. IF=1

158. Guerrini R, Parmeggiani L.

Topiramate and its clinical applications in epilepsy.

Expert Opin Pharmacother. 2006 Apr;7(6):811-23.

IF=3.1 157. Guerrini R.

Epilepsy in children.

Lancet. 2006;367:499-524. IF=21.7

156. Guerrini R, Parmeggiani L.

Practitioner review: use of antiepileptic drugs in children.

J Child Psychol Psychiatry. 2006;47:115-26. IF=2.5

155. Wieck G, Leventer RJ, Squier WM, Jansen A, Andermann E, Dubeau F, Ramazzotti A, Guerrini R, Dobyns WB.

Periventricular nodular heterotopia with overlying polymicrogyria.

Brain 2005;128:2811-21. IF=8.2

154. Piao X, Chang BS, Bodell A, Woods K, Benzeev B, Topcu M, Guerrini R, Goldberg-Stern H, Sztriha L, Dobyns WB, Barkovich AJ, Walsh CA.

Genotype-phenotype analysis of human frontoparietal polymicrogyria syndromes.

Ann Neurol 2005;58:680-7. IF=8.1

153. Sanchez-Carpintero R, McLellan A, Parmeggiani L, Cockwell AE, Ellis RJ, Cross JH, Eckhardt S, Guerrini R.

Pallister-Killian syndrome: an unusual cause of epileptic spasms.

Dev Med Child Neurol 2005 ;47:776-9. IF=2.1

152.Barkovich AJ, Kuzniecky RI, Jackson GD, Guerrini R, Dobyns WB.

A developmental and genetic classification for malformations of cortical development.

Neurology 2005 26;57:2168-78. IF=5.9

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151.Battaglia A, Guerrini R.

Chromosomal disorders associated with epilepsy.

Epileptic Disord 2005, 7:181-92. IF=1.11

150.Specchio N, Kahane P, Pasquier B, Tassi L, Guerrini R.

Resective surgery for epileptogenic dysembryoplastic neuroepithelial tumor in hemimegalencephaly.

Neurology 2005 ;65:777-8. IF=5.97

149.Groselj J, Guerrini R, Van Oene J, Lahaye M, Schreiner A, Schwalen S; TOP-INT-51 Investigators' Group.

Experience with topiramate monotherapy in elderly patients with recent-onset epilepsy.

Acta Neurol Scand 2005;112:144-50. IF=1.71

148.Ciccone R, Giorda R, Gregato G, Guerrini R, Giglio S, Carrozzo R, Bonaglia MC, Priolo E, Lagana C, Tenconi R, Rocchi M, Pramparo T, Zuffardi O, Rossi E.

Reciprocal translocations: a trap for cytogenetists?

Hum Genet 2005;117:571-82.

IF=4.32 147.Martinelli Boneschi F, Aridon P, Zara F, Guerrini R, Marini C, De Fusco M, Comi G, Casari G.

No evidence of ATP1A2 involvement in 12 multiplex Italian families with benign familial infantile seizures.

Neurosci Lett 2005 ;388:71-4. IF=2.01

146.Guerrini R, Carpay J, Groselj J, van Oene J, Schreiner A, Lahaye M, Schwalen S; TOP- INT-51 Investigators' Group.

Topiramate monotherapy as broad-spectrum antiepileptic drug in a naturalistic clinical setting.

Seizure 2005;14:371-80. IF=1.5

145. Sheen VL, Jansen A, Chen MH, Parrini E, Morgan T, Ravenscroft R, Ganesh V, Underwood T, Wiley J, Leventer R, Vaid RR, Ruiz DE, Hutchins GM, Menasha J, Willner J, Geng Y, Gripp KW, Nicholson L, Berry-Kravis E, Bodell A, Apse K, Hill RS, Dubeau F, Andermann F, Barkovich J, Andermann E, Shugart YY, Thomas P, Viri M, Veggiotti P, Robertson S, Guerrini R, Walsh CA.

Filamin A mutations cause periventricular heterotopia with Ehlers-Danlos syndrome.

Neurology 2005;64:254-62. IF=5.9

144.Guerrini R.

Genetic malformations of the cerebral cortex and epilepsy.

Epilepsia 2005;46 Suppl 1:32-7. IF=3.3

143.Pourfar MH, Guerrini R, Parain D, Frucht SJ.

Classification conundrums in paroxysmal dyskinesias: a new subtype or variations on classic themes?

Mov Disord 2005;20:1047-51. IF=3.1

142. Medina MT, Martinez-Juarez IE, Duron RM, Genton P, Guerrini R, Dravet C, Bureau M, Perez-Gosiengfiao KT, Amador C, Bailey JN, Chaves-Sell F, Delgado-Escueta AV.

Treatment of myoclonic epilepsies of childhood, adolescence, and adulthood

Adv Neurol 2005;95:307-23. IF=1.51

141. Sankar R, Wheless JW, Dravet C, Guerrini R, Medina MT, Bureau M, Genton P, Delgado- Escueta AV

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Treatment of myoclonic epilepsies in infancy and early childhood.

Adv Neurol 2005;95:289-98 IF=1.51

140. Guerrini R, Parmeggiani L, Marini C, Brovedani P, Bonanni P

Autosomal dominant cortical myoclonus and epilepsy (ADCME) with linkage to chromosome 2p11.1-q12.2

Adv Neurol 2005;95:273-9 IF=1.51

139. Guerrini R, Bonanni P, Parmeggiani L, Hallett M, Oguni H.

Pathophysiology of myoclonic epilepsies

Adv Neurol 2005;95:23-46. IF=1.51

138. Genton P, Roger J, Guerrini R, Medina MT, Bureau M, Dravet C, Delgado-Escueta AV History and classification of "myoclonic" epilepsies: from seizures to syndromes to diseases

Adv Neurol. 2005;95:1-14 IF=1.51

137. Marini C, Parmeggiani L, Masi G, Guerrini R.

Nonconvulsive status epilepticus precipitated by carbamazepine presenting as dissociative and affective disorders in adolescents.

Journal of Child Neurology, 2005;20:693-6. IF=1.01

136. Guerrini R, Filippi T.

Neuronal migration disorders: genetics and epileptogenesis.

Journal of Child Neurology, 2005;20:287-99. IF=1.01

135. Pisano T, Marini C, Brovedani P, Brizzolara D, Pruna D, Mei D, Moro S, Cianchetti C, Guerrini R.

Abnormal phonological processing in familial lateral temporal lobe epilepsy due to a new LGI1 mutation.

Epilepsia Epilepsia. 2005;46:118-23 IF=3.6

134) Parrini E, Mei D, Wright M, Dorn T, Guerrini R.

Mosaic mutations of the FLN1 gene cause a mild phenotype in patients with periventricular heterotopia

Neurogenetics 5:191-6, 2004

133) Filocamo M, Mazzotti R, Stroppiano M, Grossi S, Dravet C, Guerrini R.

Early visual seizures and progressive myoclonus epilepsy in neuronopathic Gaucher disease due to a rare compound heterozygosity (N188S/S107L).

Epilepsia 45:1154-7, 2004 IF=3.6

132) Sztriha L, Guerrini R, Harding B, Stewart F, Chelloug N, Johansen JG.

Clinical, MRI, and pathological features of polymicrogyria in chromosome 22q11 deletion syndrome

Am J Med Genet 127A:313-7, 2004

131) Palmini A, Najm I, Avanzini G, Babb T, Guerrini R, Foldvary-Schaefer N, Jackson G, Luders HO, Prayson R, Spreafico R, Vinters HV.

Terminology and classification of the cortical dysplasias.

Neurology 62(6 Suppl 3):S2-8, 2004. I F=5.3

130) Guerrini R, Mei D, Sisodiya S, Sicca F, Harding B, Takahashi Y, Dorn T, Yoshida A, Campistol J, Moro F, Kramer G, Dobyns WB, Parrini E.

Germline and mosaic mutations of FLN1 in men with periventricular heterotopia.

Neurology 2004 ;63:51-6, 2004 IF=5.3

129) D’Agostino D, Bastos A, Piras C, Bernasconi A, Grisar T, Gross Zur V, Jackson S, Juhasz S, Chugani H, Guerrini, R, Cross H, Andermann, E, Dubeau, F, Montes J, Olivier A,

Andermann F.

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Posterior quadrantic dysplasia or hemi-hemimegalencephaly: a characteristic brain malformation:

Neurology 62:2214-20, 2004 IF=5.3

128) Berkovic SF, Heron SE, Giordano L, Marini C, Guerrini R, Kaplan RE, Gambardella A, Steinlein OK, Grinton BE, Dean JT, Bordo L, Hodgson BL, Yamamoto T, Mulley JC, Zara F, Scheffer IE. Benign familial neonatal-infantile seizures: characterization of a new sodium channelopathy.

Ann Neurol 55:550-7 , 2004 IF=8.5

127) Sheen VL, Ganesh VS, Topcu M, Sebire G, Bodell A, Hill RS, Grant PE, Shugart YY, Imitola J, Khoury SJ, Guerrini R, Walsh CA.

Mutations in ARFGEF2 implicate vesicle trafficking in neural progenitor proliferation and migration in the human cerebral cortex.

Nature Genetics 36:69-76, 2004. IF=29.6

126) Striano P, Chifari R, Striano S, de Fusco M, Elia M, Guerrini R, Casari G, Canevini MP.

A new benign adult familial myoclonic epilepsy (BAFME) pedigree suggesting linkage to chromosome 2p11.1-q12.2.

Epilepsia 45:190-2, 2004 IF=3.8

125) Bonanni P, Malcarne M, Moro F, Veggiotti P, Buti D, Ferrari AR, Parrini E, Mei D, Volzone A, Zara F, Heron SE, Bordo L, Marini C, Guerrini R.

Generalized epilepsy with febrile seizures plus (GEFS+): clinical spectrum in seven Italian families unrelated to SCN1A, SCN1B, and GABRG2 gene mutations.

Epilepsia. 2004;45:149-58. IF=3.8

124) Kato M, Das S, Petras K, Kitamura K, Morohashi K, Abuelo DN, Barr M, Bonneau D, Brady AF, Carpenter NJ, Cipero KL, Frisone F, Fukuda T, Guerrini R, et al.

Mutations of ARX are associated with striking pleiotropy and consistent genotype-phenotype correlation.

Hum Mutat 2004;23:147-59. IF=6.1

123) Parmeggiani L, Seri S, Bonanni P, Guerrini R.

Electrophysiological characterization of spontaneous and carbamazepine-induced epileptic negative myoclonus in benign childhood epilepsy with centro-temporal spikes.

Clinical Neurophysiology 2004;115:50-8. IF = 2.1

122) Guerrini R, Genton P.

Epileptic syndromes and visually induced seizures.

Epilepsia. 2004;45 Suppl 1:14-8. IF=3.8

121) Wilkins AJ, Bonanni P, Porciatti V, Guerrini R.

Physiology of human photosensitivity.

Epilepsia. 2004;45 Suppl 1:7-13. IF=3.8

120) Guerrini R.

Do heterotopic neurons think?

Neurology 62,1:2004 IF=5.3

119) Guerrini R, Aicardi J.

Epileptic encephalopathies with myoclonic seizures in infants and children (severe myoclonic epilepsy and myoclonic-astatic epilepsy).

Journal of Clinical Neurophysiology ;20: 449-61, 2003 IF=2.5 118) Rossi M, Guerrini R, Dobyns WB, Andria G, Winter RM.

Characterization of brain malformations in the Baraitser-Winter syndrome and review of the literature.

Neuropediatrics. 2003;34:287-92 IF=1.5

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117) Ferrari AR, Guerrini R, Gatti G, Alessandri MG, Bonanni P, Perucca E. Influence of dosage, age, and co-medication on plasma topiramate concentrations in children and adults with severe epilepsy and preliminary observations on correlations with clinical response.

Ther Drug Monit. 2003;25:700-8. IF=2

116) Sicca F, Kelemen A, Genton P, Das S, Mei D, Moro F, Dobyns WB, Guerrini R.

Mosaic mutations of the LIS1 gene cause subcortical band heterotopia.

Neurology, 61; 1042-1046, 2003 IF=5.3

115) GuerriniR, CarrozzoR, RinaldiR and BonanniP.

Angelman Syndrome: Etiology, Clinical Features, Diagnosis and Management of Symptoms

Paediatr Drugs. 2003;5:647-661. IF=1

114) Leeflang EP, Marsh SE, Parrini E, Moro F, Dobyns WB, Guerrini R, Wheless JW, Gleeson JG.

A patient with bilateral periventricular nodular heterotopia and polymicrogyria with an

apparently balanced reciprocal translocation t(1;6)(p12;p12.2) interrupting the mannosidase alpha, class 1A, (MAN1A2) and glutathione S-transferase A2 (GSTA2) genes

Journal of Medical Genetics 2003;40:E128-133. IF=7.7

113) Guerrini R, Moro F. Andermann E, Hughes E, D’Agostino D, Carrozzo R, Bernasconi A, Flinter F, Parmeggiani L, Volzone A, Parrini E, Mei D, Jarosz JM, Morris RG, Pratt P, Tortorella G, Dubeau F, Andermann F, Dobyns WB and Das S.

Nonsyndromic Mental Retardation and Cryptogenic Epilepsy in Women with DCX Mutations

Annals of Neurology ;54:30-7, 2003 IF= 8.6

112) Guerrini R, Casari G, Marini C

The genetic and molecular basis of epilepsy

Trends in Molecular Medicine,;9:300-6, 2003 IF=7.1

111) Nabbout R, Gennaro E, Dalla Bernardina B, Dulac O, Madia F, Bertini E, Capovilla G, Chiron C, Cristofori G, Elia M, Fontana E, Gaggero R, Granata T, Guerrini R, Loi M, La Selva L, Lispi ML, Matricardi A, Romeo A, Tzolas V, Valseriati D, Veggiotti P, Vigevano F, Vallee L, Dagna Bricarelli F, Bianchi A, Zara F

Spectrum of SCN1A mutations in severe myoclonic epilepsy of infancy.

Neurology 2003;60:1961-7. IF=5.3

110) Philip N, Chabrol B, Lossi AM, Cardoso C, Guerrini R, Dobyns WB, Raybaud C, Villard L.

Mutations in the oligophrenin-1 gene (OPHN1) cause X linked congenital cerebellar hypoplasia.

Journal of Medical Genetics 2003;40:441-6. IF=7.7

109) Sicca F, Silengo M, Parrini E, Ferrero GB, Guerrini R.

Subcortical band heterotopia with simplified gyral pattern and syndactyly.

American Journal of Medical Genetic 2003;119A:207-10. IF=2.3 108) Aeby A, Guerrini R, David P, Rodesch G, Raybaud C, Van Bogaert P.

Facial hemangioma and cerebral corticovascular dysplasia: A syndrome associated with epilepsy.

Neurology 2003;25;60:1030-2. IF=5.3

107) Gatti G, Ferrari AR, Guerrini R, Bonanni P, Bonomi I, Perucca E.

Plasma gabapentin concentrations in children with epilepsy: influence of age, relationship with dosage, and preliminary observations on correlation with clinical response.

Ther Drug Monit 2003;25:54-60. IF=1.8

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106) Laporte N, Sebire G, Gillerot Y, Guerrini R, Ghariani S.

Pediatric Neurology 2002;27:307-11. IF=0.9

105) Guerrini R, Arzimanoglou A, Brouwer O.

Rationale for treating epilepsy in children.

Epileptic Disorders 2002;4(2):S9-21. IF=0.8

104) Kakita A, Hayashi S, Moro F, Guerrini R, Ozawa T, Ono K, Kameyama S, Walsh CA, Takahashi H.

Bilateral periventricular nodular heterotopia due to filamin 1 gene mutation: widespread glomeruloid microvascular anomaly and dysplastic cytoarchitecture in the cerebral cortex.

Acta Neuropathol (Berl). 2002;104:649-57. IF=2.2

103) D'Agostino MD, Bernasconi A, Das S, Bastos A, Valerio RM, Palmini A, Costa da Costa J, Scheffer IE, Berkovic S, Guerrini R, Dravet C, Ono J, Gigli G, Federico A, Booth F, Bernardi B, Volpi L, Tassinari CA, Guggenheim MA, Ledbetter DH, Gleeson JG, Lopes-Cendes I, Vossler DG, Malaspina E, Franzoni E, Sartori RJ, Mitchell MH, Mercho S, Dubeau F, Andermann F, Dobyns WB, Andermann E.

Subcortical band heterotopia (SBH) in males: clinical, imaging and genetic findings in comparison with females.

Brain. 2002;125:2507-22 IF=7.3

102. Grosse P, Guerrini R, Parmeggiani L, Bonanni P, Brown P.

Abnormal corticomuscular and intermuscular coupling in cortical myoclonus.

Brain, 2003;126:326-42 IF=7.3

101 GuerriniR, Sanchez-CarpinteroR, DeonnaT, SantucciM, BhatiaKB, MorenoT, ParmeggianiL, Dalla BernardinaB.

Early onset absence epilepsy and paroxysmal dyskinesia.

Epilepsia 2002;43:1224-9. IF=3.8

100. Chifari R, Guerrini R, Pierluigi M, Cavani S, Sgrò V, Elia M, Canger R, Canevini MP.

Mild Generalized Epilepsy and Developmental Disorder associated with Large Inv Dup(15)

Epilepsia, 2002;43:1096-1100 IF=3.8

99. Bonanni P, Parmeggiani L, Guerrini R.

Different neurophysiologic patterns of myoclonus characterize Lennox-Gastaut syndrome and Myoclonic-astatic epilepsy.

Epilepsia, 2002;43:609-615 IF=3.8

98. Moro F, Carrozzo R, Veggiotti P, Volzone A, Tortorella G, Toniolo D, Guerrini R.

Familial periventricular heterotopia: Missense and distal truncating mutations of the FLN1 gene

Neurology 2002;26;58:916-921 IF=4.8

97. Wiles CM , Brown P , Chapel H, Guerrini R , Hughes RAC, McCrone P, Newsom-Davis J, Palace J, Rees J, Rose MR, Scolding N, Webster ADB

Intravenous immunoglobulin in neurological disease: a specialist review

Journal of Neurology, Neurosurgery and Psychiatry, 2002;72:440-448 IF=2.8 96. Guerrini R, Parmeggiani L, Bonanni P, Hallett M.

Epileptic myoclonus and epilepsies with myoclonus

Epilepsy Research, in press IF=2.8

95. Guerrini R, Bonanni P, Patrignani A, Brown P, Parmeggiani L, Grosse P, Brovedani P, Moro F, Aridon P, Carrozzo R, Casari G

(16)

Autosomal dominant cortical myoclonus and epilepsy (ADCME) with complex partial and generalized seizures: a newly recognized epilepsy syndrome with linkage to chromosome 2p11.1-q12.2

Brain 2001;124: 2459-2475 IF=7.3

94. Guerrini R, Parmeggiani L, Casari G.

Epilepsy and paroxysmal dyskinesia: co-occurrenceand differential diagnosis.

Advances in Neurology 2002; 89:433-441 IF=1

93. Barkovich AJ., Kuzniecky RI, Jackson GD, Guerrini R, Dobyns WB

Classification System for Malformations of Cortical Development: Update 2001

Neurology 2001;57:2168-2178 IF=4.8

92. Guerrini R, Carrozzo R.

Epileptogenic brain malformations: clinical presentation, malformative patterns and indications for genetic testing.

Seizure 2001;10:532-547 IF=1.2

91. Ciardo F, Zamponi N, Specchio N, Parmeggiani L, Guerrini R

Autosomal recessive polymicrogyria with infatile spasms and limb deformities Neuropediatrics

2001;32:325-329 IF=1.6

90. Canevini MP, Tassi L, Fusco L, Giallonardo AT, Guerrini R, Mai R, Rubboli G, Tinuper P, Vigevano F.

Frontal lobe seizures.

Epileptic Disorder 2001;3:223-4 IF=0.5

89. Benlounis A, Nabbout R, Feingold J, Parmeggiani A, Guerrini R, Kaminska A, Dulac O Genetic predisposition to severe myoclonic epilepsy in infancy

Epilepsia 2001;42:204-9 IF=3.8

88. Kasteleijn-Nols Trenite GA, Guerrini R, Binnie CD, Genton P

Visual sensitivity and epilepsy: a proposed terminology and clasification for clinical and EEG phenomenology

Epilepsia 2001;42:692-701 IF=3.8

87. Guerrini R, Battini R, Ferrari AR, Veggiotti P, Besana D, Gobbi G, Pezzani M, Berta E, Tetto A, Beghi E, Monticelli ML, Tediosi F, Garattini L, Russo S, Rasmini P, Amadi A, Quarti P, Fabrizzi R

The costs of childhood epilepsy in Italy: comparative findings from three health care settings

Epilepsia 2001;42:641-6 IF=3.8

86. Genton P, Guerrini R, Perucca E Tiagabine in clinical practice

Epilepsia 2001;42(3):42-5 IF=3.8

85. Dulac O, Guerrini R

Epileptic syndroms in children: Lumping or splitting?

Epilepsy Research 2001;45:37-40 IF=2.8

84. Guerrini R

Idiopathic epilepsy and paroxysmal dyskinesia

Epilepsia.;42 Suppl 3:36-41, 2001 IF=3.8

83. Bernasconi A, Martinez V, Rosa-Neto P, D'Agostino D, Bernasconi N, Berkovic S, MacKay M, Harvey AS, Palmini A, da Costa JC, Paglioli E, Kim HI, Connolly M, Olivier A, Dubeau F, Andermann E, Guerrini R, Whisler W, de Toledo-Morrell L, Morrell F, Andermann F

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Surgical Resection for Intractable Epilepsy in Double Cortex Syndrome Yields Inadequate Results

Epilepsia 42:1124-1129, 2001 IF=3.8

82. Guerrini R, Carrozzo R

Epilepsy and genetic malformations of the cerebral cortex

American Journal of Medical Genetics 106:160-73, 2001 IF=2.5 81. Guerrini R, Barkovich AJ, Sztriha L, Dobyns WB

Bilateral frontal polymicrogyria: a newly recognized brain malformation syndrome

Neurology 54:909-913, 2000 IF=4.8

80. Porciatti V, Bonanni P, Fiorentini A, Guerrini R

Lack of cortical contrast gain control in human photosensitive epilepsy

Nature Neuroscience 3:259-263, 2000 IF=15.7

79. Guerrini R, Parmeggiani L, Bonanni P, Carrozzo R, Casari G

Locus for paroxysmal kinesigenic dyskinesia maps to human chromosome 16 [letter].

Neurology 55:738-739, 2000 IF=4.8

78. Guerrini R, Shanahan JL, Carrozzo R, Bonanni P, Higgs DR, Gibbons RJ

A nonsense mutation of the ATRX gene causing mild mental retardation and epilepsy

Annals of Neurology 47:117-121, 2000 IF=8.5

77. Gleeson JG, Luo RF, Grant PE, Guerrini R, Huttenlocher PR, Berg MJ, Ricci S, Cusmai R, Wheless JW, Berkovic S, Scheffer I, Dobyns WB, Walsh CA

Genetic and neuroradiological heterogeneity of double cortex syndrome

Annals of Neurology 47:265-269, 2000 IF=8.5

76. Picard F, Baulac S, Kahane P, Hirsch E, Sebastianelli R, Thomas P, Vigevano F, Genton P, Guerrini R, Gericke CA, An I, Rudolf G, Herman A, Brice A, Marescaux C, LeGuern E Dominant partial epilepsies: A clinical, electrophysiological and genetic study of 19 European families

Brain 123:1247-1262, 2000 IF=7.3

75. Fornai F, Bassi L, Gesi M, Giorgi FS, Guerrini R, Bonaccorsi I, Alessandri MG Similar increases in extracellular lactic acid in the limbic system during epileptic and/or olfactory stimulation

Neuroscience 97:447-458, 2000 IF=3.6

74. Guerreiro MM, Andermann E, Guerrini R, et al

Familial perisylvian polymicrogyria: a new familial syndrome of cortical maldevelopment

Annals of Neurology 48:39-48, 2000 IF=8.5

73. Parmeggiani L, Belmonte A, Ferrari AR, Perucca E, Guerrini R

Add-on Lamotrigine treatment in children and young adults with severe partial epilepsy: an open, prospective, long-term study

Journal of Child Neurology 15:671-674, 2000 IF=1.2 72. Bartolomei F, Gavaret M, Dravet C, Guerrini R

Familial epilepsy with unilateral and bilateral malformations of cortical development

Epilepsia 40:47-51, 1999 IF=3.8

71. Gleeson J.G, Minnerath S.R, Allen K.M, Fox J.W, Hong S, Berge M, Kuzniechy R, Reitnauer P.J, Borgatti R, Puche Mira A, Guerrini R, Holmes G, Rooney C, Berkovic S,

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Scheffer I, Cooper E.C, Ricci S, Cusmai R, Crawford T.O, Leroy R, Andermann E, Wheless J.W, Dobyns W.B, Ross M.E, Walsh C.A

Characterization of mutations in the gene doublecortin in patients with double cortex syndrome

Annals of Neurology 45:146-153, 1999 IF=8.5

70. Fogli A, Guerrini R, Moro F, Fernandez-Alvarez E, Livet MO, Renieri A, Cioni M, Pilz DT, Veggiotti P, Rossi E, Ballabio A, Carrozzo R

Intracellular levels of the LIS1 protein correlate with clinical and neuroradiological findings in patients with classical lissencephaly.

Annals of Neurology 45:154-161, 1999 IF=8.5

69. Guerrini R, Bonanni P, Nardocci N, Parmeggiani L, Piccirilli M, De Fusco M, Aridon P, Ballabio A, Carrozzo R, Casari G

Autosomal recessive rolandic epilepsy with paroxysmal exercise-induced dystonia and writer's cramp: delineation of the syndrome and gene mapping to chromosome 16p12-11.2 Annals of

Neurology 45:344-352, 1999 IF=8.5

68. Parmeggiani L, Guerrini R

Idiopathic partial epilepsy: electroclinical demonstration of a prolonged seizure with sequential rolandic and occipital involvement Seizure spread or regional susceptibility?

Epileptic Disorders 1: 35-40 1999 IF=0.5

67. Guerrini R, Canapicchi R, Dobyns WB

Epilepsy and malformations of the cerebral cortex

Rev Neurologia 14 Suppl 3:32-47 1999 IF=0.3

66. Borgatti R, Triulzi F, Zucca C, Piccinelli S, Ballottin U, Carrozzo R, Guerrini R Bilateral perisylvian polymicrogyria in three generations

Neurology 52:1910-1913 1999 IF=4.8

65. Gobbi G, Pini A, Bertani G, Menegati E, Tiberti A, Valseriati D, Besana D, Rasmini P, Guerrini R, Belmonte A, Veggiotti, P, Resi C, Lanzi G, Capovilla G, Galeone D, Milani S Prospective study of first-line vigabatrin monotherapy in childhood partial epilepsies

Epilepsy Research 35:29-37 1999 IF=2.8

64. Veggiotti P, Beccaria F, Guerrini R, Capovilla G, Lanzi G

Continuous spike-and-wave activity during slow-wave sleep: syndrome or EEG pattern?

Epilepsia 40:1593-1601 1999 IF=3.8

63. Genton P, Guerrini R, Remy C Piracetam in cortical myoclonus

Pharmacopsychiatry 32 Suppl 1:49-53 1999 IF=0.8

62. Gelisse P, Genton P, Bureau M, Dravet C, Guerrini R, Viallat D, Roger J

Are there generalised spike waves and typical absences in benign rolandic epilepsy?

Brain Development 21:390-396 1999 IF=1.2

61. Bonanni P, Guerrini R

Segmental facial myoclonus in Moebius syndrome

Movement Disorders 14:1021-1024 1999 IF=3.7

60. Guerrini R, Belmonte A, Parmeggiani L, Perucca E

Myoclonic status epilepticus following high dosage lamotrigine therapy

Brain Development 21:420-424 1999 IF=1.2

59. Guerrini R, Andermann E, Avoli M, Dobyns WB.

Cortical dysplasias, genetics and epileptogenesis

Advances in Neurology 79:95-121, 1999 IF=1

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58. Barkovich AJ, Hevner R, Guerrini R

Syndromes of bilateral symmetrical polymicrogyria

American Journal of Neuroradiology 20:1814-1821 1999 IF=2.1 57. Bertelloni S, Battini R, Baroncelli GI, Guerrini R, Viacava P, Spinelli C, Simi P Central precocious puberty in 48,XXYY Klinefelter syndrome variant

J Pediatr Endocrinol Metab 12:459-65 1999 IF=0.6

56. Gennaro E, Malacarne M, Carbone I, Riggio MC, Bianchi A, Bonanni P, Boniver C, Dalla Bernardina B, De Marco P, Giordano L, Guerrini R, Santorum E, Sebastianelli R, Vecchi M, Veggiotti P, Vigevano F, Bricarelli FD, Zara F

No evidence of a major locus for benign familial infantile convulsions on chromosome 19q12- q13.1

Epilepsia 40:1799-1803 1999 IF=3.8

55. Guerrini R, Belmonte A, Canapicchi R, Casalini C, Perucca E

Reversible pseudoatrophy of the brain and mental deterioration associated with Valproate treatment

Epilepsia 39: 27-32 1998 IF=3.8

54. Guerrini R, Belmonte A, Carrozzo R

Paroxysmal tonic upgaze of childhood with ataxia: a benign transient dystonia with autosomal dominant inheritance

Brain and Development 20:116-118 1998 IF=1.2

53. Guerrini R, Bonanni P, Parmeggiani L, Santucci M, Parmeggiani M, Sartucci F Cortical reflex myoclonus in Rett syndrome

Annals of Neurology 43: 472-479 1998 IF=8.5

52. Guerrini R, Dravet C, Genton P, Belmonte A, Kaminska A, Dulac O Lamotrigine and seizure aggravation in severe myoclonic epilepsy

Epilepsia 39:508-512 1998 IF=3.8

51. Minassian B, DeLorey T, Olsen RW, Philippart M, Zhang Q, Bronstein Y, Guerrini R, Van Ness P, Livet MO, Delgado-Escueta AV

The epilepsy of Angelman syndrome due to deletion, disomy, imprinting center and UB3A mutations

Annals of Neurology 43: 485-493 1998 IF=8.5

50. Guerrini R, Belmonte A, Canapicchi R, Volzone A, Bureau M, Genton P, Dravet C Anomalies localisés du développement cortical

Epilepsies 10:197-218, 1998 IF=NN

49. Guerrini R, Belmonte A, Genton P

Antiepileptic drug-induced worsening of seizures in children

Epilepsia 39(3):2-10 1998 IF=3.8

48. Guerrini R, Dobyns WB

Bilateral periventricular nodular heterotopia with mental retardation and frontonasal malformation

Neurology 51: 499-503 1998 IF=4.8

47. Guerrini R, Genton P, Bureau M, Parmeggiani A, Salas-Puig J, Santucci M, Bonanni P, Ambrosetto, Dravet C

Multilobar polymicrogyria, intractable drop attack seizures and sleep-related electrical status epilepticus

Neurology 51:504-512 1998 IF=4.8

46. Elia M, Guerrini R, Musumeci S, Bonanni P, Gambardella A, Aguglia U

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Myoclonic absence seizures and chromosomal abnormality syndromes

Epilepsia 39:660-663 1998 IF=3.8

45. Sossey-Alaoui K, Hartung AJ, Guerrini R, Manchester DK, Posar A, Puche-Mira A, Andermann E, Dobyns WB, Srivastava AK

Human doublecortin (DCX) and the homologous gene in mouse encode a putative Ca2- dependent signaling protein which is mutated in human X-linked neuronal migration defects

Human Molecular Genetics, 7:1327-1332 1998 IF=9

44. Pirola B, Bortotto L, Giglio S, Piovan E, Janes A, Guerrini R, Zuffardi O

Haploinsufficiency for a gene in a 8 cM region at 6q24-25 results in agenesis of corpus callosum with Probst bundles

Journal of Medical Genetics 35:1031-3, 1998 IF=3.3 43. ILAE Commission report

Myoclonus and epilepsy in childhood

Epilepsia 38:1251-1254 1997 IF=3.8

42. Bartoli A, Guerrini R, Belmonte A, Alessandrì MG, Gatti G, Perucca E

The influence of dosage, age, and comedication on steady state plasma lamotrigine concentration in epileptic children: a prospective study with preliminary assessement of correlation with clinical response

Therapeutic Drug Monitoring 19:252-260 1997 IF=1.7

41. Guerrini R, Dubeau F, Dulac O, Barkovich AJ, Kuzniecky R, Fett C, Jones-Gotman M, Canapicchi R, Cross H, Fish D, Bonanni P, Jambaque I, Andermann F

Bilateral parasagittal parieto-occipital polymicrogyria and epilepsy

Annals of Neurolgy 41:65-73 1997 IF=8.5

40. Guerrini R, Bonanni P, Parmeggiani L, Thomas P, Mattia D, Harvey S, Duchowny M.

Induction of Partial Seizures by Visual Stimulation.

Advances in Neurology 75:159-178, 1997 IF=1

39. Guerrini R, Bonanni P, Parmeggiani L, Belmonte A

Adolescent onset of idiopathic photosensitive occipital epilepsy after remission of benign rolandic epilepsy

Epilepsia 38:777-781 1997 IF=3.8

38. Guerrini R, Belmonte A, Veggiotti P, Mattia D, Bonanni P

Delayed appearance of interictal EEG abnormalities in early onset childhood epilepsy with occipital paroxysms

Brain and Development 19:343-346 1997 IF=1.2

37. Ross E, Allen KM, Srivastava AK, Featherstone T, Gleeson JG, Hirsch B, Harding BN, Andermann E, Abdullah R, Berg M, Czapansky-Bielman D, Flanders DJ, Guerrini R, Motté J, Puche Mira A, Scheffer I, Berkovic S, Scaravilli F, King RA, Ledbetter DH, Schlessinger D, Dobyns WB, Walsh CA

Linkage and physical mapping of X-linked lissencephaly/SBH (XLIS): a gene causing neuronal migration defects in human brain

Human Molecular Genetics 1997;6:555-562 IF=9

36. Ferrie CD, Beaumanoir A, Guerrini R, Kivity S, Vigevano F, Takaishi Y, Watanabe K, Mira L, Capizzi G, Costa P, Valseriati D, Grioni D, Lerman P, Ricci S, Vigliano P, Goumas-Kartalas A, Hashimoto K, Robinson RO, Panayiotopoulos CP

Early -onset benign occipital seizure susceptibility syndrome

Epilepsia 1997;38: 285-293 IF=3.8

35. Guerrini R, Dubeau F, Dulac O, Barkovich AJ, Kuzniecky R, Fett C, Jones-Gotman M, Canapicchi R, Cross H, Fish D, Bonanni P, Jambaque I, Andermann F

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Bilateral parasagittal parieto-occipital polymicrogyria and epileps (letter.)

Annals of Neurolgy 1997;42: 272-273 IF=8.5

34. Dobyns WB, Guerrini R, Czapansky-Beilman DK, Pierpoint MEM, Breningstall G, Yock DH, Bonanni P, Truwit CL

Bilateral periventricular nodular heterotopia (BPNH) with mental retardation and syndactyly in boys: a new X-linked mental retardation syndrome

Neurology 1997;49:1042-1047 IF=4.8

33. Fink JM, Dobyns WB, Guerrini R, Hirsch BA

Identification of a duplication of Xq28 associated with bilateral periventricular nodular heterotopia

American Journal of Human Genetics 1997;61: 379-387 IF=10.4

32. Guerrini R, De Lorey T, Bonanni P, Moncla A, Dravet C, Suisse G, Livet MO, Bureau M, Malzac P, Genton P, Thomas P, Sartucci F, Simi P, Serratosa JM

Cortical Myoclonus in Angelman Syndrome

Annals of Neurology 1996;39:699-708 IF=8.5

31. Dobyns WB, Andermann E, Andermann F, Czapansky-Beilman D, Dubeau F, Dulac O, Guerrini R, Hirsch B, Ledbetter DH, Lee NS, Motte J, Pinard JM, Radtke RA, Ross ME, Tampieri D, Walsh CA, Truwit CL

X-linked malformations of neuronal migration

Neurology 1996;46:1956-1964, IF=4.8

30. Guerrini R, Dravet C, Bureau M

A propos du syndrome hémiconvulsion, hémiplégie, épilepsie (HHE)

Epilepsies 1996;8:159-166 IF=NN

29. Silva ML, Cieuta C, Guerrini R, Plouin P, Livet MO, Dulac O Early clinical and EEG features of infantile spasms in Down syndrome

Epilepsia 1996;37:977-982 IF=3.8

28. Gambardella A, Aguglia U, Guerrini R, Morelli F, Zappia M, Quattrone A

Sequential occurrence of benign partial epilepsy and childhood absence epilepsy in three patients

Brain and Development 1996;18:212-215 IF=1.2

27. Genton P, Bartolomei F, Guerrini R Panic attacks mistaken for relapse of epilepsy

Epilepsia 1995;36: 48-51 IF=3.8

26. Guerrini R, Dravet C, Genton P, Bureau M, Bonanni P, Ferrari AR, Roger J Idiopathic photosensitive occipital lobe epilepsy

Epilepsia 1995;36: 883-891 IF=3.8

25. Guerrini R, Ferrari A.R., Battaglia A, Salvadori P., Bonanni P

Occipitotemporal seizures with ictus emeticus induced by intermittent photic stimulation

Neurology 1994;44:253-259 IF=4.8

24. Kuzniecky R, Andermann F, Guerrini R, et al

The epileptic spectrum in the congenital bilateral perysylvian syndrome

Neurology 1994;44:379-385 IF=4.8

23. Barkovich JA, Guerrini R, Battaglia G, Kalifa G, N'Guyen TN, Parmeggiani A, Santucci M, Giovanardi-Rossi P, Granata T, D' Incerti L

Band heterotopia: correlation of outcome with MR imaging parameters

Annals of Neurology 1994;36:609-617 IF=8.5

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22. Kuzniecky R, Andermann F, Guerrini R

Infantile Spasms: an early epileptic manifestation in some patients with the Congenital Bilateral Perisylvian Syndrome

Journal of Child Neurology 1994;9:420-423 IF=1.1

21. Kuzniecky R, Andermann F, Guerrini R, et al.

The congenital bilateral perisylvian syndrome: imaging features in a multicenter study.

American Journal of Neuroradiology 1994;15:139-144. IF=2.2

20. Guerrini R, Dravet C, Genton P, Bureau M, Roger J, Rubboli G, Tassinari CA. Epileptic negative myoclonus [letter.]

Neurology 1993;444:989-990 IF=4.8

19. Guerrini R, Dravet C, Genton P, Bureau M, Roger J, Rubboli G, Tassinari CA Epileptic negative myoclonus

Neurology 1993;43:1078-1083 IF=4.8

18. Kuzniecky R, Andermann F, Guerrini R, et al

The congenital bilateral perisylvian syndrome : A study of 31 patients

Lancet 1993;341: 607-612 IF=10.2

17. Guerrini R, Genton P, Dravet C, Viallat D, Bureau M, Horton EJ, Roger J Compulsive somatosensory self stimulation inducing epileptic seizures

Epilepsia 1992;33: 509-516 IF=3.8

16. Dravet Ch, Julian C, Legras C, Magaudda A, Guerrini R, Genton P, Soulayrol S, Giraud N, Trentin G, Roger J, Aymé S

Epilepsy, antiepileptic drugs and malformations in children of epileptic women: A French prospective cohort study

Neurology 1992;42(5):75-82 IF=4.8

15. Guerrini R, Dravet C, Raybaud C, Roger J, Bureau M, Battaglia A, Livet M, Colicchio G, Robain O

Neurological findings and seizure outcome in children with bilateral opercular macrogyric-like changes detected by magnetic resonance imaging

Developmental Medicine and Child Neurology 1992;34:694-705 IF=1.8

14. Guerrini R, Dravet C, Raybaud C, Roger J, Bureau M, Battaglia A, Livet MO, Gambarelli D, Robain O

Epilepsy and focal gyral anomalies detected by magnetic resonance imaging: electroclinico- morphological correlations and follow-up

Developmental Medicine and Child Neurology 1992;34:706-718 IF=1.8 13. Genton P, Maton B, Ogihara M, Samoggia G, Medina MT, Guerrini R, Dravet C Continuous focal SW during REM sleep in a case of acquired aphasia (Landau-Kleffner syndrome)

Sleep 1992;15:454-460 IF=3.2

12. Genton P, Guerrini R.

Effect of alcohol on action myoclonus in Lance-Adams syndrome and progressive myoclonus epilepsy.[letter]

Movement Disorders 1992;7:92 IF=3.7

11. Battaglia A, Ferrari AM, Guerrini R

Double-blind placebo-controlled trial of flunarizine as add-on therapy in refractory childhood epilepsy

Brain and Development 1991;13:217-222 IF=1.2

10. Guerrini R, Battaglia A, Gastaut H.

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Absence status triggered by pallid syncopal spells [letter]

Neurology 1991;41:1528-9 IF=4.8

9. Genton P, Guerrini R.

Alcohol and myoclonus.[letter]

Neurology 1991;41:1164-1165 IF=4.8

8. Guerrini R, Genton P, Bureau M, Dravet C, Roger J

Reflex seizures are frequent in patients with Down syndrome and epilepsy

Epilepsia 1990;31:406-417 IF=3.8

7. Guerrini R,Bureau M, Mattei MG, Battaglia A, Galland M.C, Roger J

Trisomy 12p: a chromosomal disorder associated with generalized 3Hz spike and wave discharges

Epilepsia 1990;31:557-566 IF=3.8

6. Genton P, Guerrini R

Antimyoclonic effect of alcohol in Progressive Myoclonus Epilepsy

Neurology 1990;40:1412-1416 IF=4.8

5. Santanelli P, Guerrini R, Dravet C, Genton P, Bureau M, Farnarier G.

Brainstem auditory evoked potentials in alternating hemiplegia: ictal vs interictal assessment in one case.

Clinical EEG 1990;21:51-54 IF=0.7

4. Roger J, Guerrini R, Genton P

Réduction et arrèt du traitement antiépiléptique

Revue du Praticien 1989;40:323-327 IF= NN

3. Bureau M, Guerrini R, Vigliano P, Dravet C

Contribution of ambulatory EEG recording (Medilog 9000) in a population of epileptics Neurophysiologie Clinique 1989;19:219-230 IF=0.5 2. Battaglia A, Guerrini R, Gastaut H

Epileptic seizures induced by syncopal attacks

Journal of Epilepsy 1989;2:137-145 IF=0.7

1. Rossi A, Capocchi G, Angeletti C, Guerrini R, Girelli L, Bastanzetti D.

Hereditary Ataxia: Study of Pancreatic Function

Italian Journal of Neurological Sciences 1984;(4):144-148 IF=0.2

Prof. Renzo Guerrini: Published books

Thomas P, Genton P, Guerrini R.

Clinica delle epilessie, Masson, 1993

Guerrini R, Andermann F, Canapicchi R, Roger J, Zifkin BG, Pfanner P. (eds) Dysplasias of cerebral cortex and epilepsy. Lippincott- Raven, Philadelphia-New York, 1996

Thomas P, Guerrini R, Arzimanoglou A. Le epilessie: diagnosi e trattamento. Masson, 2001 Guerrini R, Aicardi J, Andermann F, Hallett M (eds.). Epilepsy and movement disorders . Cambridge University Press, 2002.

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Arzimanoglou A, Guerrini R, Aicardi J. Epilepsy in Children. 3rd edition. Lippincott-Williams &

Wilkins, Philadelphia, 2004

V. Delgado-Escueta A. Guerrini R, Medina Marco T, Genton P, Bureau M, Dravet C (eds), Advances in Neurology Vol. 95 Myoclonic Epilepsies, Lippincott Williams & Wilkins, Philadelphia, 2005

Zaccara G, Cruccu G, Moroni F, Guerrini R, Pallanti S. I farmaci antiepilettici – Indicazioni cliniche in neurologia e psichiatria, SEE, Firenze, 2006

Guzzetta F, Dalla Bernardina B, Guerrini R

Progress in Epileptic spasms and West syndrome, J Libbey, Montrogue, 2007 Zaccara G, Guerrini R, Moroni F., La Terapia delle epilessie, SEE, Firenze, 2009

Prof. Renzo Guerrini - Book chapters in international Textbooks.

Conti V, Guerrini R. ARX Gene Mutation and X-linked Infantile Spasms. Editor Schwartzkroin P. Encyclopedia of Basic Epilepsy Research. Elsevier, vol 1-3, 2009 (in press)

Parrini E, Sgadò P, Guerrini R. Single gene mutation causing epileptogenic malformations of the celebral cortex. Editor Schwartzkroin P. Encyclopedia of Basic Epilepsy Research.

Elsevier, vol 1-3, 2009 (in press)

Guerrini R, Mari F. Cortical Myoclonus and epilepsy: Overlap and differences. Editors Shorvon S, Pedley TA, Blue Books of neurology: The Epilepsies 3. Saunders Elsevier, Philadelphia, 2009, pp 97-118

Guerrini R, Pellacani S. Epilepsy in cerebral palsy. Editor Bower E. Finnie’s handling the young child with cerebral palsy at home. Butterworth Heinemann Elsevier, 4th edition, 2009, pp 39 - 55

Parrini E, Guerrini R. Lissencephaly Type I and periventricular heterotopia. Editor Squire LR, Encyclopedia of Neuroscience, Oxford, vol 5, 2009, pp 503-512

Parrini E, Sgadò P, Guerrini R

Single Gene Mutations Causing Epileptogenic Malformations of the Cerebral Cortex. In: Philip A. Schwartzkroin, editor Encyclopedia of Basic Epilepsy Research, Vol 3. Oxford: Academic Press; 2009. pp 1521-1530

Conti V, Guerrini R

ARX Gene Mutations and X-linked infantile spasms. In: Philip A. Schwartzkroin, editor Encyclopedia of Basic Epilepsy Research, Vol 1. Oxford: Academic Press; 2009. pp 319-322 Parrini E, Guerrini R. Reelin and Lissencephaly. Editor Fatemi SH, Reelin Glycoprotein:

Structure, biology and roles in health and disease. Springer, 2008. pp 311-316

Cilio MR, Dulac O, Guerrini R, Vigevano F. Migrating Partial Seizures in infancy. Editors Jerome Engel JR., Timothy A. Pedley. Epilepsy a comprehensive textbook. Lippincott Williams

& Wilkins, Philadelphia, 2nd Edition, vol 3, 2008, pp 2323 - 2328

Gobbi G, Guerrini R, Grosso S. Late-onset childhhod occipital epilepsy (Gastaut Type). Editors Jerome Engel JR., Timothy A. Pedley. Epilepsy a comprehensive textbook. Lippincott Williams

& Wilkins, Philadelphia, 2nd Edition, vol 3, 2008, pp 2387 – 2395

Zifkin BG, Guerrini R, Plouin P. Reflex Seizures. Editors Jerome Engel JR., Timothy A.

Pedley. Epilepsy a comprehensive textbook. Lippincott Williams & Wilkins, Philadelphia, 2nd

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Edition, vol 3, 2008, pp 2559-2572

Guerrini R, Battaglia A, Carrozzo R, Gobbi G, Parrini E, Pramparo T, Zuffardi O.

Chromosomal abnormalities. Editors Jerome Engel JR., Timothy A. Pedley. Epilepsy a comprehensive textbook. Lippincott Williams & Wilkins, Philadelphia, 2nd Edition, vol 3, 2008, pp 2589-2601

Guerrini R, Pellacani S. Infantile spasms and West Syndrome: anatomo-eletroclinical patterns and etiology. Editors Guzzeta F, Dalla Bernardina B, Guerrini R. Progress in Epileptic

Disorders. Progress in Epileptic Spasms and West Syndrome. John Libbey Eurotext, Montrouge vol. 4, 2007, pp 23-41

Guerrini R, Marini C, Parrini E. Lissencephaly with and without craniofacial and extracranial abnormalities. Editor Lang F. Encyclopedia of Molecular Mechanisms of Disease. Springer Verlag,Berlin, 2007, pp

Guerrini R, Marini C, Parrini E. Cortical malformations and migration diorders. Editor Lang F.

Encyclopedia of Molecular Mechanisms of Disease. Springer Verlag,Berlin, 2007, pp Lerche H, Marini C, Guerrini R, Zara F. Idiopathic Generalized Epilepsy. Editor Lang F.

Encyclopedia of Molecular Mechanisms of Disease. Springer Verlag,Berlin, 2007, pp

Guerrini R, Bonanni P, Marini C, Parmeggiani L. The Myoclonic Epilepsies. Editor Wyllie E,Gupta A, Lachhwani DK. Treatment of epilepsy: Principles and practice. Lippincott Williams

& Wilkins,Philadelphia, 4th edition, 2005, pp 407-427

Guerrini R, Holthausen H, Parmeggiano L, Parrini E, Chiron C. Epilepsy and malformations of the celebral cortex. Editors Roger J,Thomas P,Bureau M,Hirsch E,Dravet Ch,Genton P.

Epileptic Syndromes in Infancy, Childhood and Adolescence: Edition en langue anglaise. John Libbey Eurotext, 4th edition, 2005, pp 491 -516

Guerrini R, Canapicchi R, Montanaro D. Epilepsy. Editors Tortori-Donati P,Rossi A,

Biancheri R, C. Raybaud. Pediatric neuroradiology: Head, Neck and Spine. Springer, 2005, pp 995-1048

Guerrini R, Parmegianni L, Bonanni P, Kaminska A, Dulac O. Myoclonic Astatic Epilepsy.

Editors Editors Roger J,Thomas P,Bureau M,Hirsch E,Dravet Ch,Genton P. Epileptic

Syndromes in Infancy, Childhood and Adolescence Edition en langue anglaise. John Libbey Eurotext, 4th edition, 2005, pp115- 124

Guerrini R, Parmegianni L, Marini C, Brovedani P, Bonanni P. Autosomal Dominant cortical myoclonus and epilepsy (ADCME) with linkage to chromosome 2P11.1-Q12.2. Editor Delgado- Escueta A,Guerrini R,Medina MT,Genton P,Bureau M,Dravet Ch. Advances in Neurology, Myoclonic epilepsies. Lippincott Williams & Wilkins, vol 95, 2004, pp 273-277

Genton P, Roger J, Guerrini R, Medina MT, Bureau M, Draven Ch, Delgado-Escueta A. History and classificatioc of Myoclonic epilepsies: From seizures to syndromes to diseases. Editor Delgado-Escueta A,Guerrini R,Medina MT,Genton P,Bureau M,Dravet Ch. Advances in Neurology, Myoclonic epilepsies. Lippincott Williams & Wilkins, vol 95, 2004, pp 1-14 Guerrini R, Bonanni P, Parmeggiani L, Hallett M, Oguni H. Pathophisiology of Myoclonic epilepsies. Editor Delgado-Escueta A,Guerrini R,Medina MT,Genton P,Bureau M,Dravet Ch.

Advances in Neurology, Myoclonic epilepsies. Lippincott Williams & Wilkins, vol 95, 2004, pp 23-45

Sankar R, Wheless JW, Draven Ch, Guerrini R, Medina MT, Bureau M, Genton P, Delgado- Escueta A. Treatment of myoclonic epilepsies in infancy and early childhood. Editor Delgado-

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