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1.5Optical Coherence Tomography

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Reference

1. Puliafito CA, Hee MR, Lin CP (1995) Imaging of macular diseases with optical coherence tomogra- phy. Ophthalmology 102:217–229

42 1 Principles and Methods

Optical coherence tomography (OCT) is a relatively new diagnostic imaging technique that can be used to obtain cross-sectional or tomographic images of biological tissues with micron resolution. By comparing the focal macular ERGs or multifocal ERGs with the OCT

images, a layer-by-layer correlation can be obtained on the physiology and morphology of the macular area for various macular diseases [1]. The most recent model of the OCT (OCT3) can obtain images in which the retinal layers are clearly identifiable (Fig. 1.39).

1.5 Optical Coherence Tomography

Fig. 1.39. Optical coherence tomography images of the macula in a normal subject showing the layered structure of the retina. RNFL, retinal nerve fiber layer; GCL, gan- glion cell layer; RPE, retinal pigment epithelium, PR/IS, photoreceptor inner segment; PR/OS, photorecep- tor outer segment/ INL, inner nuclear layer; ONL, outer nuclear layer; OPL, outer plexiform layer; IPL, inner plexiform layer; ELM, external limiting membrane

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