• Non ci sono risultati.

MONITORING AND SUPERVISING A DIETARY INTERVENTION TRIAL USING MODERN DATA PROCESSING SYSTEM

N/A
N/A
Info
Scarica
Protected

Academic year: 2021

Condividi "MONITORING AND SUPERVISING A DIETARY INTERVENTION TRIAL USING MODERN DATA PROCESSING SYSTEM"

Copied!
1
0
0

Caricamento.... (Visualizza il testo completo ora)

Scarica adesso ( 1 pagine )

Testo completo

(1)

MONITORING AND SUPERVISING A DIETARY INTERVENTION TRIAL USING MODERN DATA PROCESSING SYSTEM

M. J. Koski

1

, J. P. Krischer

2

1

Institute of Clinical Medicine, University of Helsinki, Helsinki, Finland,

22

DMU, H. Lee Moffitt Cancer Center Research

M

M Institute, University of South Florida, Tampa, United

States

Introduction: The recruitment for TRIGR started May 2002 and will continue until spring, 2006. Present status of TRIGR: 71 participating centers from 15 countries on 3 continents, by June 29, 2004 2398 families have been registered and 2028 infants have been randomized, 868 infants continue in the intervention after HLA screening from cord blood.

Methods: The Data Management Unit (DMU) established an electronic web- based data capture system for TRIGR. Study data is collected world wide using on-line web-based forms. The Oracle (internet) database is open continuously and the data can be entered round the clock. The data entry forms are linked to on-line logical controls and checks to reduce input errors. The TRIGR staff members have their own User Id and Password and the system is monitoring and keeping track of data entry and editing constantly. The laboratory data are captured to the DMU database using the FTP technique (File Transfer Protocol) via Internet. The tracking system for interviews, visits and blood samples is also available. Study Centers are asked to use it to report whether the scheduled contacts with the participating families have occurred. The tracking system has been designed to facilitate the monitoring of the Study Centers' compliance efforts. The Sametime videoconferencing program offers TRIGR Study members an inexpensive and effective alternative to e-mail, telephone calls and in person meetings on real time basis. To be able to design such a system, to get it ready on time, you need to have experienced staff with special knowledge and previous experience of similar trials. The management of an international multicentre intervention trial would be extremely complicated and challenging without modern technique.

Conclusions: The current system has proven its efficiency in monitoring, recruitment and compliance in study centres within TRIGR.

216

Riferimenti

Scarica adesso ( PDF - 1 pagine - 180.82 KB )

Documenti correlati

Finally, new technological solutions have been proposed to further improve the image quality of the system

However the uncertainty on the experimental PMTF has been esti- mated by performing eight independent measurements of the MTF. The error due to the phase effect has been taken

cations in ILs, new kind of salts, with very soft anions have been used.

To incorporate metals in ILs, till now, anions (chloride, bromide, dicyanamide) able to give strong complexes with metals or the introduction of specific

Mutations in cohesin and regulatory-cohesin genes have been associated with human diseases collectively termed cohesinopathies

The recent finding that human colorectal cancers cells carry mutations in cohesin genes further support the notion that cohesin is involved in genome

(2)5-2 Several microarray meta-analysis methods have been developed

A large-scale comparative study and simulation study with adequate evaluation measures are needed to provide insights and practical guidelines for choosing the

Different interpretations have been proposed for the tectonic evolution of the Maltese Islands

Indeed, during both extensional events the Maltese Islands and the Pelagian Platform were located in a foreland position, with respect to the growing Sicilian – Apennines –

io ero stato) I’ LL BE I WILL HAVE BEEN

(..mi chiederanno i miei amati lettori…. ) Essere ha due caratteristiche che lo rendono non proprio facilissimo….. 2)..per formare i tempi composti, in Italiano, utilizza le sue

In the past two years, several reforms have been approved in Italy

It focuses on the actions taken at European level in order to remove all legal and administrative barriers to trade in the services and to fully exploit the

Most of these defects have been supposed to be

By using a loss of function approach in Xenopus embryos I demonstrated in vivo, for the first time, the capacity of serotonin, via 5-HT2B receptor, to act as a