Top PDF TBX1 Transcription Factor: mechanisms of gene regulation
TBX1 Transcription Factor: mechanisms of gene regulation
... The gene studied in the thesis work was identified in an effort to isolate the gene/s involved in DiGeorge syndrome (DGS) or ...cause of CHD is the ...portion of patients with some specific ...
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Transcriptional regulation by inositol polyphosphates
... role of IPs as nuclear-signaling molecules show a series of discoveries in the phosphate-responsive signaling pathway ...regulator of Pho80-Pho85 CDK complex in a Pho81-dependent ...presence ...
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Genetic background dictates pro-angiogenic factor production in preclinical models of colorectal cancer
... levels of EGFR, as compared to BRAF-wt CRCs [75], and that signaling from EGFR could lead to re-accumulation of p-ERK and resistance to EGFR-inhibitors ...IL-8 transcription, whereas trametinib shuts ...
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MtDNA variability and nuclear gene expression in oxidative stress response: Sirtuins and Transcription Factors
... description of all transcription factors that may be involved in mitochondrial signaling pathways is out of the aim of this ...five transcription factors whose corresponding genes have ...
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Characterization of tomato (Solanum lycopersicum L.) male sterile mutants putatively affected in class B MADS-box transcription factors
... MADS-box gene was characterized, TM4 or TDR4, which is homologous of FRUITFULL (FUL) (Pnueli et ...members of class B and C are activated by floral meristem identity genes (Lohmann and Weigel, ...
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The transcription factor Foxm1 controls pro-stemness microRNAs in cerebellar neural stem cells (NSCs)
... goal of this study was to characterize new molecular Hh-related mechanisms responsible for maintaining stemness features in cerebellar ...proposal of a model where Hh-Gli signalling controls the ...
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Regulation of quorum sensing and virulence in pseudomonas aeruginosa
... rsaL transcription is strongly dependent upon LasR, this factor should not be expressed in a lasR ...lungs of CF ...environment of the CF lung ...emergence of lasR mutants could ...
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The role of Yin and Yang 1 (YY1) transcription factor in acute myeloid leukemia (AML)
... hierarchy of human hematopoiesis, working out a refined model where multipotent cells, such as HSCs and MPPs, give rise to committed unipotent progenitors, without an intermediate oligopotent CMP and MEP stage ...
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Novel molecular mechanisms involved in the stimulatory action of zinc in breast cancer
... progression of certain tumors including breast cancer ...predictor of aggressive cancer behavior as its expression has been associated with negative clinical outcomes in several cancer histotypes ...
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Identification and characterization of regulatory networks controlling the expression and activity of the alternative sigma factor pvds in Pseudomonas aeruginosa
... ability of RsmA to directly inhibit the translation of genes responsible in the biosynthesis of the exopolysaccharide Psl, and to indirectly promote the transcription of the genes ...
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Regulation of the spermatogonial niche factor GDNF by retinoic acid
... absence of retinoic acid binds to the RARE sequence and represses the transcription of the target genes also through epigenetic ...trimethylation of the lysine 27 of histone H3 ...
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Regulation of cell physiology through the modulation of estrogen receptors activities by natural and synthetic compounds
... µl of protein G beads for 1 h rotating at 4° ...µg of anti-ERα antibody (MC-20, Santa Cruz Biotechnology), then pulled down at 4° C for 1 h with 50 µl of protein G ...ml of washing buffer ...
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Study of Enzymatic Mechanisms Using Density Functional Theory and QM/MM Methods
... likelihood of the reactants state, in order to calculate the exact energy of converting the N-MIO mechanism reactants into the Single-Step mechanism reactants, we would need to do some kind of free ...
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Intragenic modulators of CFTR gene expression involved in cystic fibrosis clinical variability
... exclusion of diagnosis of ...levels of mutational search to each subject to check its carrier status, an appropriate residual genetic risk is usually chosen and the mutation search is performed with ...
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Innate, non-cytolytic CD8+ T cell-mediated suppression of HIV replication by MHC-independent inhibition of virus transcription
... ml of the diluted mono- and co-culture cell supernatants to each cytokine ...signal of the pair of duplicate spots representing each cytokine was determined and average background signal from blank ...
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<<The>> role of intrinsic and extrinsic signals in the regulation of brest cancer stem cell activity
... step of the current study, we used the R2C tumor xenograft model to examine the effects of DEXA on Leydig tumor growth in ...region of male nude mice and followed tumor growth after administration ...
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Neurophysiological mechanisms of quiet vigilance in neurodegenerative diseases: an electroencephalography research program
... diagnosis of the probable DLB was carried out in agreement with the consensus guidelines (McKeith IG et ...out of 46 DLB patients performed DaTSCAN to confirm the diagnosis of probable ...detection ...
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The evolution of human-dog communication mechanisms during the domestication process
... behavior of a recipient. Intraspecific aggression is directed toward members of the same species, whereas interspecific aggressiveness is directed toward members of different ...Bouts of ...
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Transcriptional regulation and dynamics of Arabidopsis nuclear proteome in response to auxin and oligogalacturonides
... elongation factor EF-Tu (Kunze et ...effect of NPP1 (necrosis-inducing Phytophthora protein 1) requires an intact protein and overlapping peptide fragments were inactive (Fellbrich et ...activity of ...
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Gene expression as a digital communication system
... results of gene expression in eukaryotic cells are the proteins that play a fundamental role in a target organ in the ...range of nanocommunication, the proteins are called hormones, and the ...
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