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Bioabsorbable scaffold optimization in provisional stenting: insight from optical coherence tomography

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IMAGE FOCUS

. . . .

doi:10.1093/ehjci/jet137

Online publish-ahead-of-print 24 July 2013

Bioabsorbable scaffold optimization in provisional stenting: insight from

optical coherence tomography

Nicolas Foin

1

, Matteo Ghione

2

, Alessio Mattesini

2

, Justin E. Davies

1

, and Carlo Di Mario

2

*

1

International Centre for Circulatory Health, Imperial College London, London, UK and2

NIHR Cardiovascular Biomedical Research Unit, Royal Brompton Hospital, London, UK

*Corresponding author: Royal Brompton Hospital, Sydney Street, London SW3 6NP, UK. Tel:+44 (0)207 3518616; fax: +44 (0)207 3518104, Email: [email protected]

Since the emergence of biabsorbable vascular

scaffolds (BVS), treatment of bifurcation lesions

with these devices has remained a source of

ques-tion. Although SB dilatation has been previously

performed with BVS, it is not yet clear how

dilatation across BVS strut may impact scaffold

structure.

A 74-year-old lady with hypercholesterolaemia

and type 2 diabetes was admitted to our centre

due to non-ST elevation myocardial infarction.

Patient underwent percutaneous coronary

inter-vention and an everolimus 3.0

× 28 mm BVS

(Absorb BVS, Abbott Vascular, Santa Clara, CA,

USA) was implanted in the left anterior

descend-ing artery at the level of the well developed

second diagonal branch with a moderate lesion

involving the first diagonal branch. The scaffold

was post-dilated to 3.5 mm proximally and

dilated through the origin of the side branch with

a 2.0-mm semi-compliant balloon, slowly inflated

at 12 ATM.

Final angiogram showed satisfactory results with TIMI 3 flow in the both branches. Frequency domain optical coherence tomography

(FD-OCT) pullback was performed on the implanted scaffold (C7 System, St Jude Medical, St Paul, USA). Longitudinal view and

cross-sections (Panel A, 1 – 4) demonstrate the good side branch access after dilatation of side-branch ostium through the scaffold strut.

Three-dimensional OCT reconstruction of the main vessel reveals mild distortions of the scaffold observed distally at the level of the carina

(arrow) (Panels B and C ).

Despite the distortions of the scaffold strut observed distally on the three-dimensional reconstructions (arrow), all struts remained well

apposed to the vessel (Panel A, 2).

Published on behalf of the European Society of Cardiology. All rights reserved.

&

The Author 2013. For permissions please email: [email protected]

Insights from a porcine model of chronic pressure overload

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