ATTIVITA’ SVOLTA DURANTE IL DOTTORATO DI
RICERCA
DR DE NAPOLI
A.A. 2013-2016
PUBBLICAZIONI, POSTER E ABSTRACT
1) Minimally invasive video-assisted thyroidectomy versus conventional thyroidectomy in pediatric patients
Eur J Pediatr Surg. 2014 Oct
De Napoli L., Spinelli C., Ambrosini C.E., Tomisti L, Giani C., Miccoli P.
Abstract
BACKGROUND:
Minimally invasive video-assisted thyroidectomy (MIVAT) proved to be safe and effective in the treatment of both benign and malignant disease. The aim of the present study is to compare MIVAT approach with conventional approach for total thyroidectomy in a group of 99 pediatric patients operated in the Department of General Surgery of the University of Pisa between March 2007 and July 2012.
PATIENTS:
A total of 99 pediatric patients under the age of 18 years with thyroid disease referred to our Department to undergo total thyroidectomy. Patients were divided into two groups according to the surgical technique performed: 34/99 (34.3%) patients (MIVAT group [MG]) and 65/99 (65.7%) patients,
(conventional group [CG]) who underwent total thyroidectomy, respectively, with MIVAT approach and conventional approach.
RESULTS:
In MG mean operative time for total thyroidectomy was 40 ± 6.57 minutes (range 30-60 min); postoperative hospital stay was 1 day for 18 patients (53%), 2 days for 12 patients (35.25%), 3 days for 4 patients (11.8%); transient
permanent hypoPTH in 2 cases (5.9%); transient postoperative unilateral vocal cord palsy was observed in 2 patients (5.9%). In CG mean operative time for total thyroidectomy was 49.3 ± 12.9 minutes (range 30-80 min); postoperative hospital stay was 1 day for 16 patients (24.6%), 2 days for 40 patients (61.5%), 3 days for 8 patients (12.3%), and 4 days for 1 patient (1.6%); transient
hypoPTH was observed in 23 cases (35.4%) and permanent hypoPTH in 4 cases (6.1%), who needed therapy with calcitriol and calcium carbonate; transient postoperative unilateral vocal cord palsy was observed in 4 patients (6.1%). There were no cases of permanent vocal cord paralysis in both groups. The correlation between two groups of patients showed that mean operative time was significantly lower in MG (p = 0.0007).
CONCLUSION:
Pediatric patients of MG showed a significantly lower operative time and
postoperative hospital stay with respect to pediatric patients of CG if compared with conventional technique. This result with the evidence of similar degree of completeness and rate of postoperative complications make MIVAT a valid option for the treatment of pediatric patients when performed by a well-trained staff in a third referral center.
2) Minimally invasive video-assisted thyroidectomy (MIVAT) from A to Z Surg Today. 2016 Feb
Bakkar S., Materazzi G., Biricotti M., De Napoli L., Conte M., Galleri D., Aghababyan A., Miccoli P.
Abstract
A minimal access procedure does not necessarily mean that it is minimally invasive. However, as its name implies, MIVAT is a truly minimally invasive treatment modality. The advantages it offers over its conventional counterpart are indeed related to its minimally invasive nature. Furthermore, this nature has not compromised its ability to accomplish its purpose both safely and
effectively. Ever since its introduction in the late 1990s, MIVAT has been progressively evolving. The indications for this procedure, which was initially surrounded by skepticism, have been expanding. Benign thyroid pathology is now considered only one of its indications among others. This article provides a detailed description of this minimally invasive, maximally effective and patient satisfying procedure so that it may be adopted by more surgeons around the globe for better patient care and to also encourage the development of further future advancements.
3) Pancreatoduodenectomy for groove pancreatitis Report of two cases Ann Ital Chir. 2016
Fregoli L., Palmeri M., De Napoli L., De Marco S., Pelosini M., Bertolucci A., Galatioto C., Cengeli I., Chiarugi M.
Abstract
Groove pancreatitis is a rare condition with patients having clinical characteristics similar to those of chronic pancreatitis. Differentiating on clinical and radiological basis between groove pancreatitis and paraduodenal head cancer can be extremely challenging. Due to diagnostic uncertainty and to poor response to medical treatment surgery may offer these patients the best chance of cure. As the main localization of the inflammatory process is at the groove between the duodenum and the head of the pancreas,
pancreato-duodenectomy is proposed as the most reliable surgical procedure. We report about two patients presenting with clinical and radiological features suggesting a groove pancreatitis in which control of symptoms was achieved by
pancreatoduodenectomy.
4) Lymph-node yeld in laparoscopic versus open right colectomy for colon cancer
Poster. EAES 14th World Congress of Endoscopic Surgery, Paris 25-28 June 2014
De Napoli L., Fregoli L., Bottari D., Matteucci V., Biricotti M., Aghababyan A., Bertolucci A., Furbetta N., Miccoli P., Chiarugi M.
5) Paratiroidectomia miniinvasiva video-assistita (MIVAP): una curva d’apprendimento avanzata riduce il rischio di complicanze rispetto alla chirurgia tradizionale.
Poster. SIC 2013
Frustaci G., Matteucci V., Ambrosini C.E., Fregoli L., De Napoli L., Fosso A., Biricotti M., Aghababyan A., Miccoli P.
6) Termoablazione con radiofrequenza (T-RF): nuove prospettive nel trattamento della patologia benigna e maligna della tiroide: esperienza preliminare.
Oral Communication . SIRM 2014
Pontillo Contillo B. (Pisa), Mazzeo S., Cervelli R., Cappelli C., De Napoli L., Bartolozzi C.
7) Radiofrequency ablation: new prospectives in the treatment of malignant and benign thyroid disease.
Oral Communication. CIRSE 2015
Cervelli R, Mazzeo S, Battaglia V, Cappelli C, Pontillo Contillo B, De Napoli, L, Bartolozzi C.
8) Radiofrequency ablation: new perspectives in the treatment of malignant and benign thyroid diseases.
Oral Communication. RSNA 2015
Cervelli R., Mazzeo S., Battaglia V., Cappelli C., Pontillo Contillo B., De Napoli L.