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‘PathensTDP’. Defining the role of hnRNP proteins in enhancing TDP-43 pathology

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Academic year: 2021

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Newsletter

FONDAZIONE ITALIANA DI RICERCA

PER LA SCLEROSI LATERALE AMIOTROFICA

Insieme per un futuro senza SLA

Sessione Poster

Guarda tutti gli abstract sottomessi per la sessione poster.

Soci Fondatori:

Fondazione Italiana di Ricerca per la SLA Sclerosi Laterale Amiotrofica

Via Poerio, 14 - 20129 Milano C.F.: 97511040152 IBAN: IT27A0306909606100000005190

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P1. Role of SUMOylation in TDP-43 nucleocytoplasmic transport and aggregation

P2. Regulation of UsnRNP trafficking by the Integrated Stress Response is compromised by mutant ALS proteins

P3. Decoding motor neuron diversity and subtype-specific vulnerability

P4. Nuclear and mitochondrial DNA methylation in amyotrophic lateral sclerosis

P5. Identification and validation of hits modulating C9ORF72-dipeptide repeat proteins level in vitro e vivo models

P6. AxRibALS - Axonal translatome in mouse models of Amyotrophic Lateral Sclerosis

P7. FUS-dependent phase separation initiates double strand break repair

P8. DDRNALS, DNA damage response defects in cells with TPD-43 and FUS cytoplasmic inclusions

P9. SPLICEALS - Dissecting the functional interaction between FUS and hnRNP a2/b1 in pathogenesis of ALS

P10. PathensTDP, Defining the role of hnRNP proteins in enhancing TDP-43 pathology

P11. RAN translated C9ORF72 arginine rich poly-dipeptides alter gene transcription in ALS/FTD cell model

P12. An aberrant interplay between RNA-binding proteins in Amyotrophic Lateral Sclerosis

P13. Isolation and Characterization of soluble human full-length TDP-43 associated with neurodegeneration

P14. Circulating muscle-derived mir-206 links skeletal muscle dysfunction to heart autonomic denervation

P15. MLOpathy, Membrane-less organelle pathology in ALS: identification of causes and rescuing factors

P16. Sonic hedgehog signalling pathway may control regenerative processes in a mouse model of motoneuronal loss

P17. NEVALS, Neurovascular Crosstalk in ALS Pathogenesis

P18. TDP-43 regulates the expression levels of Disc-large in Skeletal Muscles to promote the assembly of the neuromuscular synapses in Drosophila

P19. P2X7 activation enhances skeletal muscle metabolism and regeneration in SOD1G93A mouse model of amyotrophic lateral sclerosis

P20. Contribution of S100A4-regulated pathways to inflammation in ALS models

P21. Heterogeneity of neuroinflammatory responses in Amyotrophic Lateral Sclerosis (ALS) revealed at single-cell resolution: a roadmap for new target discovery

P22. Protective functions of neuroinflammation in amyotrophic lateral sclerosis

P23. Disease course variability in ALS mouse models is driven by different mcp1 mediated neuroimmune response

P24. VAPB ER-aggregates, a possible new biomarker in ALS pathology?

P25. Intercellular miscommunication in the brain and periphery: characterization of extracellular vesicle in Amyotrophic Lateral Sclerosis

P26. The Adipose tissue and the N-acetylaspartate pathway in ALS dysmetabolism

P27. Exosomes from adipose mesenchymal stem cells as innovative therapeutic approach for ALS

P28. Microvesicles and exosomes in ALS: friends or foes?

P29. Cyclophilin A (PPIA) in amyotrophic lateral sclerosis: a TDP-43 interactor with disease modifying effect

P30. HyperALS, Modulation and Hypermetabolism and Hyperexcitability as a strategy to counteract degeneration in ALS

P31. Brain changes in the structural network organization of Amyotrophic Lateral Sclerosis patients: a graph theory analysis study

P32. The 6-minute walk test as a promising outcome measure in Amyotrophic Lateral Sclerosis

P33. Prognostic power of psoas muscle in amyotrophic lateral sclerosis

P34. Curcumin and motor neuron disease: preliminary data from a double-blind, placebo-controlled clinical trial

P35. Rapamycin treatment for ALS: Preliminary data from a double-blind RCT

P36. Unravelling moral reasoning in amyotrophic lateral sclerosis: How emotional detachment modifies moral judgment inclinations

P37. Dynamic recognition of emotion in ALS patients

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