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Reduce polypharmacy

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Achieve a target Kt/V level - Optimize Ca-P-PTH levels Control for vitamin deficits - Control for nutritional status

Consider starting dialysis or increase dialysis frequency or duration Achieve a target Kt/V level - Optimize Ca-P-PTH levels

Control for vitamin deficits - Control for nutritional status

Consider starting dialysis or increase dialysis frequency or duration Optimize skin care - use topical agents

Consider psychological support Optimize skin care - use topical agents

Consider psychological support

Reduce polypharmacy Reduce polypharmacy

Hemoperfusion Oral charcoal

Gabapentin Sertraline

Oral antihistamines Hemoperfusion

Oral charcoal Gabapentin

Sertraline

Oral antihistamines

Uremic toxins – Hyperparathyroidism - Skin xerosis – Immune mediated – Opioid imbalance – Peripheral neuropathy - Increased histamine release Uremic toxins – Hyperparathyroidism - Skin xerosis – Immune mediated –

Opioid imbalance – Peripheral neuropathy - Increased histamine release Differential

Diagnosis

Intensive ESRD Treatment

Optimal Care Support Re-consider Medications

Possible Specific Treatments

Riferimenti

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