breast cancer, melanoma, and tumors of the musculoskeletal system.
The approach discussed in his 1955 paper on the primary management of osteogenic sarcoma by irradiation formed a rational and humane basis of management that was widely followed until the concept was superseded by advances in cytotoxic therapy and limb conservation surgery. Cade’s hospital career was interrupted by the Second World War in which he served in the medical branch of the Royal Air Force, making significant contributions to the safety of fighter pilots and reaching the rank of Air Vice Marshal. He was knighted in 1945. He retired from the active staff of Westminster Hospital in 1960 and was subse- quently consulting surgeon, until his death in 1973.
when he felt it a duty to set a good example to younger brothers. The next year he entered St.
Bartholomew’s Hospital Medical School.
He was noted for neatness and accuracy, pleas- ing manners, and a well-dressed appearance.
After gaining many honors and prizes, he was admitted as a member of the Royal College of Surgeons in 1852 and appointed house surgeon to St. Bartholomew’s Hospital. In July 1854 he became registrar and demonstrator of morbid anatomy and thereafter never lost his interest in this subject. In the Transactions of the Royal Society of 1869 (p. 163) he published a paper enti- tled “The Formation and Growth of the Bones of the Human Face.” This, with other scientific anatomical works, secured his election as a Fellow of the Royal Society in 1871. In the same year, on the resignation of Sir James Paget, he was elected Surgeon to St. Bartholomew’s Hos- pital and Examiner in Surgery to the University of Cambridge. He practiced in Queen Anne Street and held the appointments of Surgeon to the Charterhouse and Professor of Anatomy at the College of Surgeons. He claimed that septicemia was almost unknown in his wards and, though he did not refer to Lister’s theories of asepsis, the principle of his treatment was, in fact, a modified Listerism. His last publication, on “The Avoid- ance of Pain,” was delivered to the Section on Surgery at the Bath meeting of the British Medical Association. Having gained a prominent place in the esteem of his colleagues, and being recognized as one who represented the highest merits of British surgery, he died at the age of 49 years, and was buried at Kensal Green Cemetery on October 29, 1879.
To Callender belongs the distinction of solving the problem of the fate of the premaxilla in man.
Many anatomists had speculated on this subject.
Galen, Vesalius, Sylvius (Dubois), Colombus, Falloppius, Riolan, Tyson, Nesbitt, Albinus, Daubenton, Vicq d’Azyr, Camper, Goethe, Soemmering and other nineteenth-century anatomists had made contradictory contributions to the literature. It was due to the careful investi- gations of Callender that the truth of the devel- opment of the maxilla emerged.
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