• Non ci sono risultati.

Data assimilation of daily concentrations has been employed to estimate PM2.5 surface values

N/A
N/A
Protected

Academic year: 2022

Condividi "Data assimilation of daily concentrations has been employed to estimate PM2.5 surface values"

Copied!
1
0
0

Testo completo

(1)

TITLE: Spatio-temporal exposure to fine particles and polycyclic aromatic hydrocarbons, short term effects on mortality in Rome, 2011-2012 - the EXPAH project

Authors: Massimo Stafoggia (1), Francesco Forastiere (1), Angelo Cecinato (2), Giulia Cesaroni (1), Annunziata Faustini (1), Sandro Finardi (3), Maria Pia Gatto (4), Monica Gherardi (4), Cinzia Perrino (2), Paola Romagnoli (2), Camillo Silibello (3), Claudio Gariazzo (4), EXPAH Study Group.

(1) Department of Epidemiology, Lazio Region Health Service, Rome, Italy (2) CNR-IIA, Montelibretti, Rome, Italy

(3) ARIANET, Milan, Italy

(4) INAIL Research center, Monteporzio Catone, Rome, Italy Primary category: ambient air pollution

Secondary category: exposure assessment of air pollutants Abstract (max 2000 characters, including spaces)

Background: short-term association between fine particles (PM2.5) and mortality is well established, while evidence on the effects of PM components, e.g. polycyclic aromatic hydrocarbons (PAHs) is less clear. The project EXPAH aimed at estimating population exposure to PM2.5 and PAHs using spatio-temporal modelling, and investigating their short-term association with mortality in Rome, Italy.

Methods: PM2.5, PAHs and benzo[a]pyrene (b[a]p) were measured in 18 locations in Rome during two field campaigns from December 2011 to May 2012 to complement Rome air quality network.

In addition, PM2.5 and PAHs were modeled by means of the chemical transport model FARM using measurements for model validation and improvement. Data assimilation of daily concentrations has been employed to estimate PM2.5 surface values. Daily mean exposures were estimated for each km2 of Rome from June 2011 to May 2012. All natural deaths were collected and geo-referenced. A case-crossover analysis was applied to estimate the percent increases of mortality per interquartile ranges (IQR) of the pollutants.

Results: there were 22,172 natural deaths. Lagged 2-5 IQRs increases of 0.65 ng/m3 in PAHs, 0.17 ng/m3 in b[a]p and 14.78 μg/m3 in PM2.5 were associated with 2.03% (95% confidence interval=0.47, 3.60), 1.91% (0.36, 3.48) and 1.45% (-2.39, 5.44) increases in natural mortality.

Effects were higher on respiratory mortality, in elderly, women and in winter, with a linear concentration-response. As sensitivity analysis, we computed daily averages of the three exposures over Rome and applied conventional time-series methods. Effects on mortality did not change for PAHs and b[a]p, while they were considerably lower for PM2.5.

Conclusions: a novel spatio-temporal model was applied to estimate population exposure to PAHs and PM2.5 in Rome, and to investigate short-term health effects of PAHs. We found evidence of an association of all the exposures with mortality, especially for respiratory causes.

Riferimenti

Documenti correlati

dogs and based on this model, to indicate the best sampling times that enable a precise clearance 22.. estimation using a low number

When 2 or 3 sampling times were considered, for the dogs CKD+ with medium or high creatinine values (example 2 and 3), the best results were obtained from the combination of

Level of portability of EXPAH methodology: The EXPAH project created an unforeseen compilation of standard methodologies for the assessment of population exposures

Taking into account the considerations about the different domains of the input variables between the training samples and all the samples, a further device has been adopted

Moreover, since measurements campaigns and preliminary simulations evidenced the need to reduce wintertime concentrations, while Cle scenario foresees a growth of

In a randomized trial comparing standard vs high-dose induction (ClinicalTrials.gov #NCT00495287), we studied early peripheral blast cell clearance (PBC) as a rapid predictive assay

Nevertheless, we notice that the tem- perature gradient estimated from the radiation temperature in the ’blue’ 506-668 nm continua are mostly larger than the corresponding gradi-

Due to the satisfactory effects of the removal/degradation of PAHs both during the sorption and oxidation the studies aiming the determination of removal efficiency of