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20 Mobilizing Resources: The Assessment and Treatment of Depression in Primary Care

Depression is one of the most common problems seen in primary care and is associated with significant morbidity, mortality, and economic cost.

At any one time, between 5 and 9% of primary care patients suffer from major depression, and an equal number have other depressive dis- orders, including dysthymia and minor depression (1). Depression causes as much disability and impact on quality of life as major chronic medical illnesses (e.g., ischemic heart disease, strokes, or diabetes), and it neg- atively affects the outcome of most chronic illnesses. Despite its high prevalence and morbidity, depression remains underdiagnosed and under- treated in primary care. It is estimated that up to 50% of depressed patients are undetected in primary care, and those that are detected are often inadequately treated (2). Underdetection results in part because these patients present with somatic rather than psychological symptoms, espe- cially chronic pain, fatigue, and sleep problems. Many patients have co-existing medical problems with symptoms that overlap with depression.

The diagnosis of depression is hampered by competing demands faced by primary care clinicians (3). Compounding this, most reimbursement systems create additional challenges by not paying for mental health diagnoses and “carving out” depression treatment to mental health professionals.

Depression is influenced by biological, psychological, and social factors.

The family and social factors are often overlooked when assessing and treating depression in primary care. This chapter will provide an overview of the identification, assessment, and treatment of depression in primary care, with a focus on how the primary care clinician can mobilize and inte- grate individual and interpersonal resources. We will emphasize an inter- personal approach to understanding and treating depression and the link between family relationships and depression.

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An Interpersonal Approach to Depression

Family relationships can have a powerful influence on the onset, course, and treatment of depression, and depression has a negative impact on the quality of most family and social relationships. Interpersonal factors, espe- cially marital distress and family criticism, can precipitate depressive episodes and relapse, and worsen depressive symptoms. Individuals in a dis- tressed marriage are three times more likely to develop depression than are those in nondistressed relationships (4). In turn, depression often results in more negative and critical behaviors toward one’s spouse or partner, which can further worsen marital distress and depressive symptoms. Stressful marital or family events (e.g., illness or death of a family member, separa- tion, or divorce) often precede the onset of depression (5).

Social and interpersonal stressors that disrupt the patient’s normal sources of support and nurturance can trigger depression. When these dis- ruptions occur, the depressed person typically turns to family members to obtain reassurance and support. Although partners and family members ini- tially respond positively, over time family members may feel overburdened, irritated, or “burned out.” The patient may then perceive these responses as rejection and feel more needy or depressed. This pattern may spiral over time as family members offer varying degrees of support that the patient experiences as inadequate, and the depressive symptoms are maintained or intensified (6).

Identification and Assessment of Depression

The assessment of depression should simultaneously address three aspects of the system: the depressed person, the partner, and any relationship prob- lems between the two of them. The family-oriented clinician is in an ideal position to conduct such an assessment and to initiate treatment. In the following sections we will discuss guidelines for assessing and treating depressed persons from an interpersonal perspective.

Mrs. Pulcino, a 36-year-old Italian-American woman, came to see Dr.

C. for the fourth time in 2 months. Mrs. Pulcino was married and had two children, one of whom was school aged (see genogram, Fig. 20.1).

She worked outside the home as an aide in a nearby nursing home. Mr.

Pulcino drove a delivery truck and also maintained a 100-acre farm.

Mrs. Pulcino reported symptoms of fatigue, headaches, and diffuse muscle pains. In the previous 3 months, she had also seen Dr. C. for a cold and an intestinal flu.

Mrs. Pulcino told Dr. C. she was afraid there was something seriously wrong with her. None of Dr. C.’s tests revealed any organic causes for her symptoms; however, Mrs. Pulcino was clearly feeling ill.

Identification and Assessment of Depression 347

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Some patients talk openly with their clinician about their emotional or interpersonal problems, but others do not. Somatic complaints are often the primary way in which depressive symptoms are presented in a medical setting. The clinician’s first task is to recognize the signs that assessment for depression may be necessary. An increase in the number of office visits, functional complaints, infections, and reports of pain and anxiety by the patient are often a harbinger of a depressive episode.

Screening

The U.S. Preventive Services Task Force recommends the routine screen- ing for depression “in clinical practices that have systems in place to assure accurate diagnosis, effective treatment and follow up (7).” This new rec- ommendation is based upon research that clearly demonstrates that early detection and treatment of depression in primary care results in reduced morbidity, especially in settings where there is a systematic approach to assessing and treating depression.

Screening for depression can be accomplished by asking two simple ques- tions during routine office visits:

• Over the past 2 weeks, have you felt down, depressed, or hopeless?

• Over the past 2 weeks, have you felt little interest or pleasure in doing things?

Recently moved to Florida

36 Mrs. Pulcino Depression Mr. Pulcino

5 Emily

d. 1969

Figure 20.1. The Pulcino family.

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Identification and Assessment of Depression 349 These questions appear to be as effective as longer screening instruments (e.g., Beck Depression Inventory) (8). Whether a more open-ended ques- tion (e.g., “How has your mood or spirits been over the past few weeks?”) works as well as these yes/no questions has not been studied.

The two preceding questions should be asked routinely of patients who are at increased risk for depression, especially those with a prior history of depression, unexplained somatic symptoms, comorbid psycho- logical conditions (esp. any anxiety disorders), substance abuse, and chronic pain. When a patient screens positive, a more detailed interview is needed to make an accurate diagnosis. The PRIME-MD offers an efficient and validated method for conducting such an assessment (9) (see Table 20.1).

An assessment for depression should focus on the patient in the context of his or her significant relationships. An interpersonal approach helps the clinician gather a broad range of information and develop a treatment team that can include the patient and his or her main supports. Key elements in the assessment process include: evaluating the depressed individual, involv- ing the partner, exploring relationship difficulties, suicide assessment, and measuring the effect of other life stressors.

In preparation for involving significant others in treatment, it is helpful to assess how the patient’s symptoms may affect or be affected by his or her relationships with others:

• Who is most concerned about you?

• How do others respond to how you are feeling?

• What do others think is the cause of your depression?

• What do others suggest to remedy the situation?

These questions explore interpersonal factors that may contribute to the patient’s depressive symptoms as well as help to alleviate them.

Table 20.1. Depression assessment questions (PRIME-MD) During the past 2 weeks, have you often been bothered by:

Little interest or pleasure in doing things?

Feeling down, depressed, or hopeless?

Trouble falling/staying asleep, sleeping too much?

Feeling tired or having little energy?

Poor appetite or overeating?

Feeling bad about yourself—or that you are a failure?

Trouble concentrating on things (e.g., reading the newspaper)?

Moving or speaking so slowly that other people could have noticed? Or being so fidgety or restless that you have been moving around more than usual?

Thoughts that you would be better off dead or of hurting yourself?

A positive response to five or more of these questions is consistent with depression.

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Dr. C. begins the assessment of Mrs. Pulcino with these individual and interpersonal dimensions in mind.

Dr. C. learned that Mrs. Pulcino had been having difficulty sleeping for almost 4 months and had gained 10 pounds over the same period. At times she felt confused and helpless to change her situation. Mrs.

Pulcino often wished it would “all come to an end,” but when asked specifically if she wanted to hurt herself, Mrs. Pulcino denied any suicidal ideation.

Mrs. Pulcino said her husband worried about her and often suggested she rest more, but was impatient with her chronic fatigue. When asked if she considered herself depressed, Mrs. Pulcino said, yes. She also wondered if there was something physically wrong that made her feel depressed.

Dr. C. reiterated that none of the tests showed any significant physiological abnormalities, but he agreed that Mrs. Pulcino definitely felt ill and was depressed. He suggested that it would be valuable to have Mr. Pulcino come with her to the next visit. Dr. C. explained that Mr. Pulcino’s input would help Dr. C. get a bigger picture of the problem and would be a chance for the three of them to work together on a treatment direction.

Involving the Partner

The patient’s partner is an invaluable asset during assessment and treat- ment. A partner can provide information about depressive symptoms that the patient may not recognize. In cases where antidepressant medication is indicated, patients in a supportive, satisfactory marital relationship respond more favorably (10).

By seeing the couple together, the clinician can gain a better under- standing of how their interactions may play a part in the patient’s depres- sion. Partners of depressed patients are often depressed themselves. It is important to assess whether or not the partner may be depressed, and, if so, to what degree the partner needs support. Even when partners do not report significant relational dissatisfaction they may still interact in ways that maintain the patient’s depression.

The following questions to the partner can help the clinician gather more information and understand the interpersonal dimension of the patient’s depression.

• How can you tell when your partner is depressed?

• What do you do when he or she is depressed? How does your partner respond?

• Can you describe times when your partner does not feel depressed?

• Have you yourself ever felt depressed?

• To both partners:

• How do you think your relationship has been affected by this problem?

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After getting to know Mr. Pulcino, Dr. C. discussed Mrs. Pulcino’s depression and her husband’s perception of her illness:

At the conjoint interview, Dr. C. noticed immediately that Mrs.

Pulcino was quieter and more withdrawn than in her individual visits.

Mr. Pulcino watched her continuously and spoke to her in soothing tones. When she appeared unresponsive, Mr. Pulcino sat back, looked at Dr. C. and shrugged his shoulders.

Mr. Pulcino said his wife had been depressed for several months. He knew she was having a bad day if she was not dressed when he returned from morning chores for breakfast. They both reported that Mr. Pulcino tried to talk to his wife or hug her, but she would sometimes not respond and he would fall silent or leave suddenly for the barn. Mr. and Mrs.

Pulcino thought their marriage was a good one, but they were both exhausted and edgy with each other because Mrs. Pulcino’s depression was not lifting. The only time her depressive behavior seemed to decrease was when they watched TV together on Thursday nights.

She might laugh then and Mr. Pulcino would feel better. When Dr. C.

asked Mrs. Pulcino if she ever worried about her husband, she said she was concerned that he was becoming more moody. Mr. Pulcino agreed.

Mr. Pulcino’s efforts to support his wife did not coincide with times when Mrs. Pulcino would accept his support. Mrs. Pulcino would consequently feel frustrated and then withdraw, whereas Mr. Pulcino would feel rejected and become more depressed. Mrs. Pulcino would then try to support her again and the cycle would continue. Dr. C. felt the Pulcino’s had a strong marriage, but that they were stuck in a pattern that supported rather than alleviated Mrs. Pulcino’s depression.

Suicide Assessment

All patients with depression should be carefully assessed for suicide risk.

Suicide is the eighth leading cause of death in the United States, and most patients see their primary care clinician within 1 month of committing suicide. Major risk factors for suicide in depressed patients include being male, older, unemployed, unmarried or living alone, and substance abuse.

The following series of questions (continued until the response is, no) are useful for suicide assessment:

• Have you thought that life is not worth living or that you wished you were dead? (passive ideation)

• Have you thought about hurting yourself?. . . killing yourself? (active ideation)

• Have you thought about the manner in which you might end your life?

(plans)

• Do you possess what it would take (e.g., pills, firearms) to carry out your plan to end your life? (means)

• Do you intend to kill yourself with these means? (intent)

Identification and Assessment of Depression 351

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All patients with active suicidal thoughts should be referred to a mental health professionals, and those with plans need urgent evaluation. Those with the means and intent to commit suicide usually need immediate hospitalization.

Patients should initially be asked about suicidal ideation, when they are alone and may be more revealing about such thoughts; however, it can be very useful to involve partners and other family members in discussions about suicidal risk. Family members are often unaware of the suicide risk and, in cases of mild risk, can be helpful in monitoring the patient and his or her mood as well as removing dangerous items (e.g., pills and weapons) from the home. If family members become hypervigilant (e.g., not letting the patient out of their sight), however, or there is ongoing conflict, collab- oration with a family therapist is indicated.

Life Stressors

Depressed persons report more stressful life events before the onset of depressive symptoms than nondepressed persons. These may include deaths, changes in work or financial status, the birth of a child, the depar- ture of an offspring, geographical relocations, issues related to individual and family life cycles, and recent illnesses.

Some questions to guide the discussion of life stressors include:

What changes or stresses have occurred in your lives in the past year?

What impact have these changes had on you and your family?

Do you feel these changes play a part in your depression?

In the next segment, Dr. C. asked about suicidal risk, and the Pulcinos discuss the significant events that had recently occurred.

Mrs Pulcino admitted that she had wished that she was not alive on several occasions over the past month, but never felt like hurting herself.

She and her husband agreed that they should remove any medication from the bathroom cabinet that might be dangerous. During the last year Mr. Pulcino had taken a part-time job driving a delivery truck because of financial problems. To help out, Mrs. Pulcino had taken responsibility for keeping the books on the family business. It was then that she realized how serious their financial problems were. At the same time, Mrs. Pulcino’s mother, who had lived down the road, moved to Florida after her retirement. This move had been particularly difficult for Mrs.

Pulcino, who depended on her mother for support and childcare. As for the children, Emily, the oldest, had started kindergarten. Mr. and Mrs.

Pulcino had not recognized how many stressful changes had occurred in the previous year. Mrs. Pulcino wondered if all the changes had been

“too much” for her.

With a clearer understanding of Mrs. Pulcino’s symptoms and their relationship to her interpersonal context and life situation, Dr. C. began treatment with Mr. and Mrs. Pulcino.

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Treatment of Depression in Primary Care

The choice of treatments of depression depends both upon the severity of the patient’s symptoms, the patient’s preference, and the clinician’s skills (11). A treatment plan should be negotiated with the patient and his or her partner. Antidepressants and psychotherapy (cognitive-behavior or interpersonal) are equally effective for mild and moderate major depres- sion. Patients with severe major depression or suicidal ideation should be referred to a psychiatrist for evaluation and medication. Minor depres- sion (e.g., dysthymia or subthreshold depression) responds best to psychotherapy.

Depression is a chronic disease and should be managed using the prin- ciples of chronic disease management (12). This includes close collabora- tion with mental health professionals for medication management and/or psychotherapy and long-term follow up. Our discussion of treatment will focus on how to change individual and interpersonal behaviors that may perpetuate depression. We will conclude with guidelines for the use of anti- depressant medication.

The Partner as a Collaborator in Treatment

By involving the partner, the clinician can help the couple interact in ways that may alleviate some of the patient’s depressive symptoms. To that end it is important to gauge any overinvolvement or underinvolvement the partner may have with the patient’s problem. Overinvolved partners take too much responsibility for the depressed person; thus, they inadvertently support the depressed person’s feeling of helplessness. Underinvolved part- ners appear distant or even hostile toward the depressed person, who may then feel abandoned and hopeless (13).

The clinician can help the partner achieve a moderate level of involve- ment that is both supportive of the patient’s needs and respectful of the patient’s autonomy. For example, the partner who fixes all the meals for a depressed person may be encouraged by the clinician to prepare one meal per day while assisting the depressed person in preparing the others. On the other hand, to a partner who withdraws when the depressed person requests emotional support, the clinician may suggest he or she offer encouragement once per day before it is sought. In those ways the clinician can help bring balance to the partner’s involvement around the patient’s symptoms. A more balanced approach may also reduce pressure on the partner and benefit the couple’s relationship as well. When relational discord makes it difficult for the couple to work together or is clearly a con- tributing factor in the patient’s depression, the clinician should engage the couple in primary care couple counseling or negotiate a referral to a marital therapist (see Chaps. 14 and 25).

When involving the partner in treatment, it is important to:

Treatment of Depression in Primary Care 353

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1. Maintain an alliance with the patient and the partner.

A relationship already exists between the clinician and patient, so it is important to develop rapport with the partner, and try to maintain a balanced relationship with the couple.

2. Avoid blaming the partner for the patient’s depression or making the partner responsible for alleviating the patient’s depression.

The partner often feels overburdened by the patient’s depression and may need to be relieved of excessive guilt or responsibility.

3. Focus on ways in which the partner can be a resource in treatment.

Emphasize the strengths in the relationship that may be utilized to help the patient, and ask the patient to tell his or her partner how he or she can be helpful.

4. Recognize and discuss the effect the patient’s depression may have on the partner.

Partners of depressed people often experience depressive symptoms themselves.

5. Support the partner in looking after his or her own needs.

By addressing his or her own needs the partner may find additional strength and energy to help the patient.

Working with the Depressed Individual

How much primary care counseling the primary care clinician provides or whether the clinician refers the patient to a psychotherapist will depend upon the clinician’s skills, interest, time availability, and the patient’s pref- erences (see Chap. 25). There are some basic knowledge and skills, however, that all primary care clinicians should have when working with depressed patients.

Depressed people tend to feel powerless and angry about changing their situation. Because they often depend on others to meet many of their personal needs, depressed people are extremely sensitive to criticism and rejection. At times, their perception of whether or not others are critical or rejecting is distorted. Depressed persons have often experienced many losses and their grief is frequently unresolved. The pain of these negative experiences may only confirm their feelings of worthlessness. To protect themselves, depressed people may withdraw from what seems like a world that does not care, yet continue to hope that someone else will make things better. The further they withdraw, the more powerless they feel; the more powerless they feel, the more they count on others; the more they count on others, the more vulnerable they are to disappointment; the more disap- pointed they are, the more they withdraw; and so on.

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Therapeutic approaches that are most effective with depressed patients are brief, goal-oriented, and focused on behavioral change. The central task of the clinician is to help the patient interrupt the downward spiral of depressive symptoms that results from feelings of powerlessness and dependency on others. Primary care counseling can aid the patient in identifying small, manageable tasks that will increase his or her sense of personal mastery and competence. Treatment strategies for working with the depressed individual follow:

1. Focus on changing behaviors.

An increase in meaningful activity has a positive effect on the patient’s affect.

2. Go slowly.

Do not facilitate too much change too quickly when the patient’s resources may be depleted.

3. Take small measurable steps.

Help the patient identify concrete, observable behavior that he or she can do (e.g., a patient who found it extremely difficult to leave the house started with a plan of going outside twice per week).

4. Utilize feedback from the patient’s partner.

Involve the partner in observing positive changes in the patient and in giving the patient feedback on these changes.

These strategies are designed to increase the patient’s sense of agency and self-determination. The resulting positive feedback can help the patient internalize those changes and begin to feel more self-confident.

Utilizing Antidepressant Medication

Most primary care clinicians have the skills to prescribe and monitor anti- depressant medication for uncomplicated depression. Studies show that most primary care patients either do not take the prescribed medication or stop taking it within the first month or two. Ongoing psychoeducation about depression and antidepressant treatment has been shown to improve out- comes and should be provided by the primary care clinician (14). Patients should be seen within 2 weeks of starting antidepressants and followed reg- ularly throughout treatment. At each visit the patient and his or her partner should be asked about side effects and compliance with medication and re- minded that medication should be continued even when the patient is feel- ing better and is no longer depressed.

Medication is a family issue and should be treated as one. The effective- ness of antidepressants in major depression is well established, but it can be greatly influenced by relationship factors in the patient’s life. For that Treatment of Depression in Primary Care 355

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reason, pharmacological treatment should be approached as a family issue and integrated into an overall treatment plan that includes ongoing counseling with the patient and partner. The involvement of significant others can improve compliance and provide the support the patient will need in the early stages of pharmacological treatment. By the same token, antidepressant medication can increase the patient’s concentration, energy, and motivation to work on relationship issues. Combining medication and family counseling has a beneficial effect on both modalities.

When utilizing antidepressant medication as part of a comprehensive treatment plan, it is important to:

1. Present the option of using medication to the patient and partner together whenever possible.

This provides the clinician with the opportunity to educate the couple on the effects and side effects of antidepressant medication and to answer their questions.

2. Involve the patient and partner in a plan to monitor, decrease, and even- tually discontinue the medication.

This may include planning a medication regimen together, monitoring signs of change, and continuing counseling during the transition from use to nonuse. The couples that work together around the use of medication can mirror and support other changes they are making in the relationship.

3. Look for signs of under or overinvolvement of the partner in the patient’s treatment.

The underinvolved partner is unlikely to come to office visits and may have withdrawn emotionally from the patient. The overinvolved partner may have assumed or taken responsibility for the medication which may result in more passivity and depression in the patient or conflict in the relation- ship.

4. Request that the patient tell family members how they can be most helpful in assisting the patient’s adherence to antidepressant medication.

Negotiating the amount and type of help that family members provide will help to prevent over or underinvolvement.

After discussion with the couple, Dr. C. started Mrs. Pulcino on antidepressants and began seeing her every 2 weeks for brief primary care counseling and to monitor her medication. Mr. Pulcino agreed to attend these sessions as a resource to Dr. C. and as a support to his wife.

During treatment Dr. C. helped the patient choose small, observable tasks to accomplish what both partners felt would help Mrs. Pulcino feel less depressed. For example, Mrs. Pulcino’s first goal was to get up each day by 7:00 AM. Mr. Pulcino encouraged his wife and often reminded

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her of this goal. When she did not get up, he would become critical and they would argue. Dr. C. helped Mr. Pulcino make changes in the way he offered support. Mr. Pulcino was encouraged by Dr. C. to give positive verbal feedback to Mrs. Pulcino on days she met her goal, but to say nothing when she did not. In discussing the issue, Mrs. Pulcino decided that getting up at 7:00 AMthree times per week was a more reasonable goal.

Over the next few weeks Mrs. Pulcino was able to meet her new goal and the couple reported less conflict. Nevertheless, Mrs. Pulcino was still not sleeping well and had difficulty concentrating during the day.

It was during this period that Mrs. Pulcino discussed feeling depressed at other times in her life, as had her mother. Mrs. Pulcino’s father had died when she was 2 years old. She felt her mother was still sad about the loss. Mrs. Pulcino herself was tearful when discussing her father. Dr.

C. discussed the use of antidepressant medication as a tool to help Mrs.

Pulcino sleep better and regain some energy. He emphasized that the use of medication should be in conjunction with ongoing counseling to continue working on behavior changes and to monitor the effect of the medication.

Over the next 2 months Mrs. Pulcino began to sleep better and was able to accomplish her daily responsibilities, but the couple reported an increase in their arguing. Mrs. Pulcino felt her husband did not give her enough emotional support; and Mr. Pulcino said his wife demanded too much. Dr. C. suggested the Pulcinos see a marriage counselor to address these issues. He clarified that he would continue to see them together periodically to monitor the medication and would be in regular contact with their counselor.

The Pulcinos accepted the referral and saw a couples’ therapist for a year during which time they were able to improve their relationship. Dr.

C. proceeded cautiously with decreasing the medication and it was discontinued after 9 months.

The primary care clinician can effectively treat the depressed patient, espe- cially if he or she has developed a network of professional resources with which to collaborate. Mobilizing the resources of the patient and family pro- vides the foundation for comprehensive, integrated treatment. Focused primary care counseling and medication builds on this foundation to ensure successful treatment.

References

1. Katon W: The epidemiology of depression in medical care. Int J Psychiatr Med 1987;17:93–112.

2. Simon GE, VonKorff M: Recognition, management, and outcomes of depres- sion in primary care. Arch Fam Med 1995;4:99–105.

3. Klinkman MS: Competing demands in psychosocial care. A model for the identification and treatment of depressive disorders in primary care. Gen Hosp Psychiatr 1997;19:98–111.

References 357

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4. Whisman MA: The association between depression and marital dissatisfaction.

In: Beach SR (Ed): Marital and Family Processes in Depression Washington DC:

American Psychological Association, 2001.

5. Clarkin JF, Haas GL: Asssessment of affective disorders and their interpersonal contexts. In: Clarkin JF, Hass GL (Eds): Affective Disorders and the Family. New York: Guilford Press, 1988, pp. 29–50.

6. Joiner TE: Depression’s vicious screen: Self-propagating and erosive processes in depression chronicity. Clin Psychol. Sci Prac 2000;7:203–218.

7. US Preventive Task Force (2002) Screening for depression. In: Guide to Preventive Services Third ed. International Publishing, 2002.

8. Whooley MA, Avins AL, Miranda J, & Browner WS: Case finding instruments for depression: two questions are as good as many. J Gen Int Med 1997;

12:439–445.

9. Spitzer RL, Kroenke K, & Williams JBW: Validity and utility of a self-report version of PRIME-MD: the PHQ primary care study. JAMA 1999;282:

1737–1744.

10. Weissman MM, Prusoff BA, DiMascio A, Neu C, Gorklaney M, & Klerman GL:

The efficacy of drugs and psychotherapy in the treatment of acute depressive episodes. Am J Psychiatry 1979;136:555–558.

11. Depression Guideline Panel: Depression in primary care. Vol, 2: treatment of Major Depression. Rockville MD: Agency for Health Care Policy and Research, US DHHS, 1993.

12. Dickinson WP: The management of depression as a chronic disease. In:

DeGruy F, Dickinson P (eds): 20 Common Problems in Primary Care. New York: McGraw Hill, 2002.

13. Coyne JC: Depression, biology, marriage and marital therapy. Fam Proc 1987;

13(4):393–407.

14. Katon W, von Korff M, Lin E, et al.: Collaborative management to achieve treatment guidelines: impact on depression in primary care. JAMA 1995;

273:1026–1031.

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Protocol: Assesment and Treatment of Depression in Primary Care

Screening for Depression

All patients should be screened:

• Over the past 2 weeks, have you felt down, depressed, or hopeless?

• Over the past 2 weeks, have you felt little interest or pleasure in doing things?

Questions to Ask If the Answers to Either of These Questions Is Positive

During the past 2 weeks, have you often been bothered by:

• Little interest or pleasure in doing things?

• Feeling down, depressed, or hopeless?

• Trouble falling/staying asleep, sleeping too much?

• Feeling tired or having little energy?

• Poor appetite or overeating?

• Feeling bad about yourself—or that you are a failure?

• Trouble concentrating on things (e.g., reading the newspaper)?

• Moving or speaking so slowly that other people could have noticed? Or being so fidgety or restless that you have been moving around more than usual?

• Thoughts that you would be better off dead or of hurting yourself?

A positive response to five or more of these questions is consistent with depression.

Questions to Explore the Family Context

To the Patient

• Who is most concerned about you?

• How do others respond to how you are feeling?

• What do others think is the cause of your depression?

• What do others suggest to remedy the situation?

To the Partner:

• How can you tell when your partner is depressed?

• What do you do when he or she is depressed? How does your partner respond?

• Can you describe times when your partner does not feel depressed?

• Have you yourself ever felt depressed?

Protocol: Assesment and Treatment of Depression in Primary Care 359

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To Both Partners:

• How do you think your relationship has been affected by this problem?

Assess for Suicide Risk

• Have you thought that life is not worth living or that you wished you were dead? (passive)

• Have you thought about hurting yourself?. . . killing yourself? (active)

• Have you thought about the manner in which you might end your life?

(plans)

• Do you possess what it would take (e.g., pills, firearms) to carry out your plan to end your life? (means)

Treatment

• Negotiate whether to use medication, counseling, or both.

• Refer to a psychiatrist when severe or complicated depression or suicide risk.

• Consider referral to a psychotherapist for counseling.

• If there is marital distress or relationship difficulties, refer to a couple therapist.

• Involve partner in treatment

• See patient for regularly scheduled follow-up visits, even when patient is feeling better.

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