Alvise Perosa Perosa

Sustainable

Sustainable ((Chemical Chemical) ) Solutions Solutions

Alvise

Alvise Perosa Perosa

Sustainable

Sustainable

…to

…to avoid avoid this this::

Rethinking

Rethinking Nature Nature equals

equals Rethinking

Rethinking Science… Science…

…from

…from a a chemist chemist’s ’s perspective perspective..

Nature

Science

Chemistry

Role of chemistry

Role of chemistry? ?

Impact on:

Impact on:

ENERGY

ENERGY PRODUCTS PRODUCTS

Oil

Oil--based industry based industry

Burn 90%

Burn 90% Products 10% Products 10%

Where are we now Where are we now? ?

Burn 90%

Burn 90% Products 10% Products 10%

Green Green Chemistry Chemistry Green: possibly

Green: possibly Sustainable: no!

Sustainable: no!

Green

Green Chemistry Chemistry

Alternative chemical processes

Greener solvents

Safer chemicals Molecular design

Higher efficiency

The way forward:

The way forward:

Learn from Nature Learn from Nature

Move away from fossil resources Move away from fossil resources

Grand challenge Grand challenge What Nature does

What Nature does

H₂O → H₂ + O₂

CO₂

O₂

H₂O

One step a

One step a a a time time

Alternative energy sources Alternative energy sources

Wind

Wind SolarSolar NuclearNuclear Renewable resourcesRenewable resources

Energy

Energy EnergyEnergy EnergyEnergy Energy + ProductsEnergy + Products

Green: yes Green: yes

Sustainable: yes

Sustainable: yes

Renewable biomass Renewable biomass

Chemical Chemical technologies technologies

Fuels

Fuels Bio Bio--based based

chemical products chemical products

CO

CO _{2 2}

Aim: the

Aim: the biorefinery biorefinery

Lignin:

Lignin:

renewable chemical feedstock renewable chemical feedstock

•• Useful as a source for a Useful as a source for a variety of chemicals variety of chemicals variety of chemicals variety of chemicals

•• Only source of Only source of

renewable aromatics.

renewable aromatics.

Last generation

Last generation biofuels biofuels

H O H H O

H O H H

Low Value $ O

Low Value $ O O High Value $ High Value $

H H

H O

O O H H

H O

Low Value $ High Oxygen

Low Value $ High Oxygen

High Value $

Low Oxygen

High Value $

Low Oxygen

Chemistry Chemistry: :

Green AND Beautiful Green AND Beautiful

•• It It improves improves knowledge knowledge of of the the laws laws of of Nature Nature

•• It It teaches teaches to to apply apply the the laws laws of of Nature Nature

•• … and … and it it’s ’s creative creative

•• … and … and it it’s ’s creative creative

That

That makes makes us us “ “molecular molecular designers designers” ”

Creative Creative

N

NH₃ CO₂CH₃

H

+ O

P OH O

OH -

NH₂ CO₂CH₃ Na₂CO₃

H₂O a₂

a₁

N

NH₂ CO₂H

H H₃PO₄

(H₃CO)₂CO (DMC)

CH₃OH SOCl₂ b

CO₂CH₃ +

N

NH₂

H N

NH₃

H + HCl Cl-

a₃

1

O c

O

O

H

N

NH₂ CO₂CH₃

O O H

Cl-

2

N

N

O O H

N O

O CH₃

Tadalafil

95%

d + e 88%

Examples in Japan

Examples in Japan

Examples in Japan

Examples in Japan

Examples in Japan

Examples in Japan

Some

Some of of the key the key issues issues involved involved::

•• Knowledge Knowledge

•• Development Development

•• Environment Environment

•• Health Health

•• Products Products

•• Processes Processes

•• Materials Materials

•• Health Health

•• Security Security

•• Economy Economy

In a SUSTAINABLE way!

In a SUSTAINABLE way!

•• Materials Materials

•• Fuels Fuels

•• Energy Energy

In summary:

In summary:

Thank

Thank you you!!