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AIM  OF  THE  STUDY

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AIM  OF  THE  STUDY    

The  aim  of  this  study  was  to  describe  in  a  population-­‐based  cohort  of  pediatric  age,  the  variations,   if   any,   that   occurred   in   the   last   two   decades   in   children   and   adolescents   with   a   probable   or   definite  diagnosis  of  IBD  (CD,  UC  or  IBD-­‐U).  Data  were  obtained  from  a  registry  developed  in  the   North-­‐West  of  France  (with  its  headquarters  based  in  Lille)  that  enrolled  all  cases  (children  and   adults)   of   Inflammatory   Bowel   Diseases   in   a   population-­‐based   manner   (Registre   des   maladies   inflammatoires   chroniques   de   l'intestin   du   Nord-­‐Ouest,   EPIMAD)   (http://www3.univ-­‐ lille2.fr/epiweb/travaux/epimad).  

In   particular,   we   looked   for   variation   in   the   incidence,   in   the   clinical   presentation   and   in   the   changes   of   the   diagnostic   work-­‐up   that   occurred   for   these   diseases   over   a   period   of   21   years   (1988-­‐2008)  in  pediatric  patients  (diagnosis  <  17  years).  In  addition,  we  searched  for  any  factors   that  could  influence  the  delay  in  diagnosis,  either  positively  or  negatively.    

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