Fattori tra soggetti N Stato ATTIVA 11 CONTR 9 REM 12 Test multivariatia
Effetto Valore F Ipotesi df Gradi di libertà dell'errore Sig.
Intercetta Traccia di Pillai 1,000 2936,043b 22,000 8,000 ,000 Lambda di Wilks ,000 2936,043b 22,000 8,000 ,000 Traccia di Hotelling 8074,117 2936,043b 22,000 8,000 ,000 Radice di Roy 8074,117 2936,043b 22,000 8,000 ,000 Stato Traccia di Pillai 1,927 10,740 44,000 18,000 ,000 Lambda di Wilks ,000 44,455b 44,000 16,000 ,000 Traccia di Hotelling 1112,779 177,033 44,000 14,000 ,000 Radice di Roy 1099,982 449,992c 22,000 9,000 ,000
a. Disegno: Intercetta + Stato b. Statistica esatta
c. La statistica è un limite superiore per F che fornisce un limite inferiore per il livello di significatività.
Test degli effetti fra soggetti
Sorgente Variabile dipendente Somma dei quadrati Tipo III df Media dei quadrati F Sig.
Modello corretto CD4CD25sangue 7,773a 2 3,887 3,366 ,048 CD4CD25mucosa 21,836b 2 10,918 10,761 ,000 CD4CD25hisangue 35,463c 2 17,731 33,478 ,000 CD4CD25himucosa 33,877d 2 16,939 18,972 ,000 CD4LAPsangue 1,878e 2 ,939 2,823 ,076 CD4LAPmucosa 52,794f 2 26,397 31,187 ,000 CD4Foxp3sangue 13,467g 2 6,734 22,830 ,000 CD4Foxp3mucosa 157,680h 2 78,840 81,963 ,000 CD4LAPFoxp3sangue 2,505i 2 1,252 25,443 ,000 CD4LAPFoxp3mucosa 30,404j 2 15,202 44,984 ,000 CD25LAPsangue 1,851k 2 ,926 1,865 ,173 CD25LAPmucosa 141,723l 2 70,861 49,580 ,000 CD25Foxp3sangue 6644,169m 2 3322,085 201,015 ,000 CD25Foxp3mucosa 14804,375n 2 7402,188 173,712 ,000 CD25LAPFoxp3sangue 12,537o 2 6,269 21,677 ,000 CD25LAPFoxp3mucosa 106,195p 2 53,097 118,304 ,000 CD25hiLAPsangue 4,158q 2 2,079 1,617 ,216 CD25hiLAPmucosa 287,020r 2 143,510 44,830 ,000 CD25hiFoxp3sangue 12850,973s 2 6425,487 218,779 ,000 CD25hiFoxp3mucosa 26207,330t 2 13103,665 499,884 ,000 CD25hiLAPFoxp3sangue 22,250u 2 11,125 24,724 ,000 CD25hiLAPFoxp3mucosa 110,466v 2 55,233 75,574 ,000 Intercetta CD4CD25sangue 1221,097 1 1221,097 1057,490 ,000 CD4CD25mucosa 1595,175 1 1595,175 1572,240 ,000 CD4CD25hisangue 176,726 1 176,726 333,672 ,000 CD4CD25himucosa 286,733 1 286,733 321,148 ,000 CD4LAPsangue 107,451 1 107,451 323,115 ,000 CD4LAPmucosa 248,299 1 248,299 293,356 ,000 CD4Foxp3sangue 86,721 1 86,721 294,015 ,000 CD4Foxp3mucosa 365,137 1 365,137 379,600 ,000 CD4LAPFoxp3sangue 13,307 1 13,307 270,349 ,000 CD4LAPFoxp3mucosa 93,848 1 93,848 277,708 ,000 CD25LAPsangue 483,455 1 483,455 973,959 ,000 CD25LAPmucosa 965,397 1 965,397 675,465 ,000 CD25Foxp3sangue 20352,278 1 20352,278 1231,490 ,000 CD25Foxp3mucosa 55083,673 1 55083,673 1292,683 ,000 CD25LAPFoxp3sangue 90,207 1 90,207 311,946 ,000 CD25LAPFoxp3mucosa 356,586 1 356,586 794,494 ,000 CD25hiLAPsangue 1680,920 1 1680,920 1307,443 ,000 CD25hiLAPmucosa 2552,232 1 2552,232 797,263 ,000 CD25hiFoxp3sangue 38855,141 1 38855,141 1322,964 ,000 CD25hiFoxp3mucosa 73985,731 1 73985,731 2822,436 ,000 CD25hiLAPFoxp3sangue 274,870 1 274,870 610,876 ,000 CD25hiLAPFoxp3mucosa 821,424 1 821,424 1123,932 ,000 Stato CD4CD25sangue 7,773 2 3,887 3,366 ,048 CD4CD25mucosa 21,836 2 10,918 10,761 ,000 CD4CD25hisangue 35,463 2 17,731 33,478 ,000 CD4CD25himucosa 33,877 2 16,939 18,972 ,000 CD4LAPsangue 1,878 2 ,939 2,823 ,076
CD4LAPmucosa 52,794 2 26,397 31,187 ,000 CD4Foxp3sangue 13,467 2 6,734 22,830 ,000 CD4Foxp3mucosa 157,680 2 78,840 81,963 ,000 CD4LAPFoxp3sangue 2,505 2 1,252 25,443 ,000 CD4LAPFoxp3mucosa 30,404 2 15,202 44,984 ,000 CD25LAPsangue 1,851 2 ,926 1,865 ,173 CD25LAPmucosa 141,723 2 70,861 49,580 ,000 CD25Foxp3sangue 6644,169 2 3322,085 201,015 ,000 CD25Foxp3mucosa 14804,375 2 7402,188 173,712 ,000 CD25LAPFoxp3sangue 12,537 2 6,269 21,677 ,000 CD25LAPFoxp3mucosa 106,195 2 53,097 118,304 ,000 CD25hiLAPsangue 4,158 2 2,079 1,617 ,216 CD25hiLAPmucosa 287,020 2 143,510 44,830 ,000 CD25hiFoxp3sangue 12850,973 2 6425,487 218,779 ,000 CD25hiFoxp3mucosa 26207,330 2 13103,665 499,884 ,000 CD25hiLAPFoxp3sangue 22,250 2 11,125 24,724 ,000 CD25hiLAPFoxp3mucosa 110,466 2 55,233 75,574 ,000 Errore CD4CD25sangue 33,487 29 1,155 CD4CD25mucosa 29,423 29 1,015 CD4CD25hisangue 15,360 29 ,530 CD4CD25himucosa 25,892 29 ,893 CD4LAPsangue 9,644 29 ,333 CD4LAPmucosa 24,546 29 ,846 CD4Foxp3sangue 8,554 29 ,295 CD4Foxp3mucosa 27,895 29 ,962 CD4LAPFoxp3sangue 1,427 29 ,049 CD4LAPFoxp3mucosa 9,800 29 ,338 CD25LAPsangue 14,395 29 ,496 CD25LAPmucosa 41,448 29 1,429 CD25Foxp3sangue 479,270 29 16,527 CD25Foxp3mucosa 1235,745 29 42,612 CD25LAPFoxp3sangue 8,386 29 ,289 CD25LAPFoxp3mucosa 13,016 29 ,449 CD25hiLAPsangue 37,284 29 1,286 CD25hiLAPmucosa 92,836 29 3,201 CD25hiFoxp3sangue 851,723 29 29,370 CD25hiFoxp3mucosa 760,190 29 26,213 CD25hiLAPFoxp3sangue 13,049 29 ,450 CD25hiLAPFoxp3mucosa 21,195 29 ,731 Totale CD4CD25sangue 1291,260 32 CD4CD25mucosa 1663,527 32 CD4CD25hisangue 232,655 32 CD4CD25himucosa 353,195 32 CD4LAPsangue 124,022 32 CD4LAPmucosa 334,418 32 CD4Foxp3sangue 110,599 32 CD4Foxp3mucosa 563,632 32 CD4LAPFoxp3sangue 17,491 32 CD4LAPFoxp3mucosa 136,219 32 CD25LAPsangue 513,948 32 CD25LAPmucosa 1180,875 32 CD25Foxp3sangue 28610,084 32 CD25Foxp3mucosa 74001,733 32 CD25LAPFoxp3sangue 114,460 32 CD25LAPFoxp3mucosa 492,128 32 CD25hiLAPsangue 1726,633 32 CD25hiLAPmucosa 3045,269 32 CD25hiFoxp3sangue 54930,258 32 CD25hiFoxp3mucosa 105385,420 32 CD25hiLAPFoxp3sangue 312,188 32 CD25hiLAPFoxp3mucosa 975,444 32 Totale corretto CD4CD25sangue 41,260 31 CD4CD25mucosa 51,259 31 CD4CD25hisangue 50,822 31 CD4CD25himucosa 59,770 31 CD4LAPsangue 11,522 31 CD4LAPmucosa 77,340 31 CD4Foxp3sangue 22,021 31 CD4Foxp3mucosa 185,575 31 CD4LAPFoxp3sangue 3,932 31 CD4LAPFoxp3mucosa 40,204 31 CD25LAPsangue 16,247 31 CD25LAPmucosa 183,171 31 CD25Foxp3sangue 7123,439 31 CD25Foxp3mucosa 16040,120 31 CD25LAPFoxp3sangue 20,923 31 CD25LAPFoxp3mucosa 119,210 31 CD25hiLAPsangue 41,442 31 CD25hiLAPmucosa 379,857 31 CD25hiFoxp3sangue 13702,697 31
CD25hiFoxp3mucosa 26967,519 31
CD25hiLAPFoxp3sangue 35,298 31
CD25hiLAPFoxp3mucosa 131,661 31
a. R quadrato = ,188 (R quadrato corretto = ,132) b. R quadrato = ,426 (R quadrato corretto = ,386) c. R quadrato = ,698 (R quadrato corretto = ,677) d. R quadrato = ,567 (R quadrato corretto = ,537) e. R quadrato = ,163 (R quadrato corretto = ,105) f. R quadrato = ,683 (R quadrato corretto = ,661) g. R quadrato = ,612 (R quadrato corretto = ,585) h. R quadrato = ,850 (R quadrato corretto = ,839) i. R quadrato = ,637 (R quadrato corretto = ,612) j. R quadrato = ,756 (R quadrato corretto = ,739) k. R quadrato = ,114 (R quadrato corretto = ,053) l. R quadrato = ,774 (R quadrato corretto = ,758) m. R quadrato = ,933 (R quadrato corretto = ,928) n. R quadrato = ,923 (R quadrato corretto = ,918) o. R quadrato = ,599 (R quadrato corretto = ,572) p. R quadrato = ,891 (R quadrato corretto = ,883) q. R quadrato = ,100 (R quadrato corretto = ,038) r. R quadrato = ,756 (R quadrato corretto = ,739) s. R quadrato = ,938 (R quadrato corretto = ,934) t. R quadrato = ,972 (R quadrato corretto = ,970) u. R quadrato = ,630 (R quadrato corretto = ,605) v. R quadrato = ,839 (R quadrato corretto = ,828)
Test post-hoc
Stato
Confronti multipli Bonferroni
Variabile dipendente (I) Stato (J) Stato Differenza media (I-J)
Deviazione standard Errore
Sig. Intervallo di confidenza 95% Limite inferiore Limite superiore
CD4CD25sangue ATTIVA CONTR 1,200 ,4830 ,057 -,027 2,427 REM ,833 ,4486 ,220 -,306 1,973 CONTR ATTIVA -1,200 ,4830 ,057 -2,427 ,027 REM -,367 ,4738 1,000 -1,571 ,837 REM ATTIVA -,833 ,4486 ,220 -1,973 ,306 CONTR ,367 ,4738 1,000 -,837 1,571 CD4CD25mucosa ATTIVA CONTR 1,2818 * ,45273 ,025 ,1315 2,4322 REM 1,9285* ,42046 ,000 ,8601 2,9968 CONTR ATTIVA -1,2818 * ,45273 ,025 -2,4322 -,1315 REM ,6467 ,44416 ,468 -,4819 1,7752 REM ATTIVA -1,9285 * ,42046 ,000 -2,9968 -,8601 CONTR -,6467 ,44416 ,468 -1,7752 ,4819 CD4CD25hisangue ATTIVA CONTR 2,1364 * ,32711 ,000 1,3052 2,9675 REM 2,2714* ,30379 ,000 1,4995 3,0433 CONTR ATTIVA -2,1364 * ,32711 ,000 -2,9675 -1,3052 REM ,1350 ,32091 1,000 -,6804 ,9504 REM ATTIVA -2,2714 * ,30379 ,000 -3,0433 -1,4995 CONTR -,1350 ,32091 1,000 -,9504 ,6804 CD4CD25himucosa ATTIVA CONTR 2,0455 * ,42470 ,000 ,9663 3,1246 REM 2,2455* ,39442 ,000 1,2433 3,2476 CONTR ATTIVA -2,0455 * ,42470 ,000 -3,1246 -,9663 REM ,2000 ,41666 1,000 -,8587 1,2587 REM ATTIVA -2,2455 * ,39442 ,000 -3,2476 -1,2433 CONTR -,2000 ,41666 1,000 -1,2587 ,8587 CD4LAPsangue
ATTIVA CONTR REM -,1427 ,4473 ,25919 ,24071 1,000 ,285 -,2113 -,7544 1,1059 ,4689
CONTR ATTIVA -,4473 ,25919 ,285 -1,1059 ,2113 REM -,5900 ,25429 ,083 -1,2361 ,0561 REM ATTIVA ,1427 ,24071 1,000 -,4689 ,7544 CONTR ,5900 ,25429 ,083 -,0561 1,2361 CD4LAPmucosa ATTIVA CONTR 2,7091 * ,41351 ,000 1,6584 3,7598 REM 2,7008* ,38403 ,000 1,7250 3,6765 CONTR ATTIVA -2,7091 * ,41351 ,000 -3,7598 -1,6584 REM -,0083 ,40568 1,000 -1,0391 1,0225 REM ATTIVA -2,7008 * ,38403 ,000 -3,6765 -1,7250 CONTR ,0083 ,40568 1,000 -1,0225 1,0391 CD4Foxp3sangue ATTIVA CONTR 1,2545 * ,24410 ,000 ,6343 1,8748 REM 1,4345* ,22670 ,000 ,8585 2,0106 CONTR ATTIVA -1,2545 * ,24410 ,000 -1,8748 -,6343 REM ,1800 ,23948 1,000 -,4285 ,7885 REM ATTIVA -1,4345 * ,22670 ,000 -2,0106 -,8585 CONTR -,1800 ,23948 1,000 -,7885 ,4285
CD4Foxp3mucosa ATTIVA CONTR 4,5000 * ,44082 ,000 3,3799 5,6201 REM 4,7925* ,40939 ,000 3,7523 5,8327 CONTR ATTIVA -4,5000 * ,44082 ,000 -5,6201 -3,3799 REM ,2925 ,43248 1,000 -,8064 1,3914 REM ATTIVA -4,7925 * ,40939 ,000 -5,8327 -3,7523 CONTR -,2925 ,43248 1,000 -1,3914 ,8064 CD4LAPFoxp3sangue ATTIVA CONTR ,5270 * ,09972 ,000 ,2736 ,7803 REM ,6253* ,09261 ,000 ,3900 ,8606 CONTR ATTIVA -,5270 * ,09972 ,000 -,7803 -,2736 REM ,0983 ,09783 ,969 -,1502 ,3469 REM ATTIVA -,6253 * ,09261 ,000 -,8606 -,3900 CONTR -,0983 ,09783 ,969 -,3469 ,1502 CD4LAPFoxp3mucosa ATTIVA CONTR 1,8691 * ,26129 ,000 1,2052 2,5330 REM 2,1633* ,24266 ,000 1,5467 2,7798 CONTR ATTIVA -1,8691 * ,26129 ,000 -2,5330 -1,2052 REM ,2942 ,25634 ,782 -,3572 ,9455 REM ATTIVA -2,1633 * ,24266 ,000 -2,7798 -1,5467 CONTR -,2942 ,25634 ,782 -,9455 ,3572 CD25LAPsangue ATTIVA CONTR ,3455 ,31667 ,853 -,4592 1,1501 REM -,2545 ,29409 1,000 -1,0018 ,4927 CONTR ATTIVA -,3455 ,31667 ,853 -1,1501 ,4592 REM -,6000 ,31067 ,190 -1,3894 ,1894 REM ATTIVA ,2545 ,29409 1,000 -,4927 1,0018 CONTR ,6000 ,31067 ,190 -,1894 1,3894 CD25LAPmucosa ATTIVA CONTR 4,4909 * ,53734 ,000 3,1256 5,8562 REM 4,3842* ,49903 ,000 3,1162 5,6522 CONTR ATTIVA -4,4909 * ,53734 ,000 -5,8562 -3,1256 REM -,1067 ,52717 1,000 -1,4462 1,2328 REM ATTIVA -4,3842 * ,49903 ,000 -5,6522 -3,1162 CONTR ,1067 ,52717 1,000 -1,2328 1,4462 CD25Foxp3sangue ATTIVA CONTR 32,4909 * 1,82721 ,000 27,8481 37,1337 REM 28,3742* 1,69695 ,000 24,0625 32,6860 CONTR ATTIVA -32,4909 * 1,82721 ,000 -37,1337 -27,8481 REM -4,1167 1,79262 ,087 -8,6716 ,4382 REM ATTIVA -28,3742 * 1,69695 ,000 -32,6860 -24,0625 CONTR 4,1167 1,79262 ,087 -,4382 8,6716 CD25Foxp3mucosa ATTIVA CONTR 48,5727 * 2,93402 ,000 41,1177 56,0278 REM 42,2727* 2,72485 ,000 35,3491 49,1963 CONTR ATTIVA -48,5727 * 2,93402 ,000 -56,0278 -41,1177 REM -6,3000 2,87848 ,110 -13,6140 1,0140 REM ATTIVA -42,2727 * 2,72485 ,000 -49,1963 -35,3491 CONTR 6,3000 2,87848 ,110 -1,0140 13,6140 CD25LAPFoxp3sangue ATTIVA CONTR 1,3727 * ,24170 ,000 ,7586 1,9869 REM 1,2719* ,22447 ,000 ,7015 1,8423 CONTR ATTIVA -1,3727 * ,24170 ,000 -1,9869 -,7586 REM -,1008 ,23713 1,000 -,7033 ,5017 REM ATTIVA -1,2719 * ,22447 ,000 -1,8423 -,7015 CONTR ,1008 ,23713 1,000 -,5017 ,7033 CD25LAPFoxp3mucosa ATTIVA CONTR 3,9673 * ,30112 ,000 3,2022 4,7324 REM 3,7273* ,27965 ,000 3,0167 4,4378 CONTR ATTIVA -3,9673 * ,30112 ,000 -4,7324 -3,2022 REM -,2400 ,29542 1,000 -,9906 ,5106 REM ATTIVA -3,7273 * ,27965 ,000 -4,4378 -3,0167 CONTR ,2400 ,29542 1,000 -,5106 ,9906 CD25hiLAPsangue ATTIVA CONTR -,6073 ,50964 ,729 -1,9022 ,6877 REM ,2844 ,47330 1,000 -,9182 1,4870 CONTR ATTIVA ,6073 ,50964 ,729 -,6877 1,9022 REM ,8917 ,49999 ,255 -,3788 2,1621 REM ATTIVA -,2844 ,47330 1,000 -1,4870 ,9182 CONTR -,8917 ,49999 ,255 -2,1621 ,3788 CD25hiLAPmucosa ATTIVA CONTR 6,9918 * ,80419 ,000 4,9485 9,0352 REM 5,5968* ,74686 ,000 3,6991 7,4945 CONTR ATTIVA -6,9918 * ,80419 ,000 -9,0352 -4,9485 REM -1,3950 ,78896 ,263 -3,3997 ,6097 REM ATTIVA -5,5968 * ,74686 ,000 -7,4945 -3,6991 CONTR 1,3950 ,78896 ,263 -,6097 3,3997 CD25hiFoxp3sangue ATTIVA CONTR 46,0303 * 2,43583 ,000 39,8411 52,2195 REM 38,4636* 2,26218 ,000 32,7156 44,2116 CONTR ATTIVA -46,0303 * 2,43583 ,000 -52,2195 -39,8411 REM -7,5667* 2,38973 ,011 -13,6387 -1,4946 REM ATTIVA -38,4636 * 2,26218 ,000 -44,2116 -32,7156 CONTR 7,5667* 2,38973 ,011 1,4946 13,6387 CD25hiFoxp3mucosa ATTIVA CONTR 65,1000 * 2,30123 ,000 59,2528 70,9472 REM 55,7000* 2,13717 ,000 50,2696 61,1304 CONTR ATTIVA -65,1000 * 2,30123 ,000 -70,9472 -59,2528 REM -9,4000* 2,25767 ,001 -15,1365 -3,6635 REM ATTIVA -55,7000 * 2,13717 ,000 -61,1304 -50,2696 CONTR 9,4000* 2,25767 ,001 3,6635 15,1365 CD25hiLAPFoxp3sangue ATTIVA CONTR 1,3464 * ,30150 ,000 ,5803 2,1124 REM 1,9364* ,28000 ,000 1,2249 2,6478 CONTR ATTIVA -1,3464 * ,30150 ,000 -2,1124 -,5803 REM ,5900 ,29579 ,167 -,1616 1,3416 REM ATTIVA -1,9364 * ,28000 ,000 -2,6478 -1,2249 CONTR -,5900 ,29579 ,167 -1,3416 ,1616
CD25hiLAPFoxp3mucosa ATTIVA CONTR 3,8000 * ,38425 ,000 2,8237 4,7763 REM 3,9900* ,35685 ,000 3,0833 4,8967 CONTR ATTIVA -3,8000 * ,38425 ,000 -4,7763 -2,8237 REM ,1900 ,37697 1,000 -,7679 1,1479 REM ATTIVA -3,9900 * ,35685 ,000 -4,8967 -3,0833 CONTR -,1900 ,37697 1,000 -1,1479 ,7679
Le medie sono basate sulle osservazioni.
Il termine di errore è Media dei quadrati(errore) = ,731. *. La differenza media è significativa al livello
