È stata effettuata un'analisi di enrichment dei GO-term "biological process" per ogni set di geni associati a ognuno dei 48 bicluster significativi. Per ogni bicluster sono stati utilizzati in input tutti i geni
ai quali è stato possibile associare un codice identificativo Uniprot. In totale sono stati analizzati 163 geni, i p-value sono stati corretti con il metodo Bonferroni, ed è stato utilizzato un livello di soglia è
pari a un p-value di 5·10
-2. 43 bicluster su 48 sono risultati arricchiti per almeno un termine dell'ontologia. Poi sono state calcolate le occorrenze di tutti i termini associati ai bicluster. La lista di sotto
mostra tutti i termini arricchiti, uno per riga. Il campo "Bic (#)" e il campo "Bic (%)" mostrano il numero e la percentuale di bicluster di cui i geni sono risultati arricchiti per il termine, "GO-term" e
"Descrizione" descrivono il termine in questione, "P-value (min)" e "P-value (max)" mostrano il minimo e il massimo p-value calcolato per i rispettivi termini. Gli enrichment sono stati effettuati
avvalendosi di NET-GE. I termini sono disposti in ordine di numero di bicluster decrescente.
Bic (#) Bic (%) GO-term Descrizione P-value (min) P-value (max)
22 51,00% GO:0030182 neuron differentiation 6,23E-08 3,70E-02 20 47,00% GO:0032774 RNA biosynthetic process 5,90E-08 3,44E-02 19 44,00% GO:0006357 regulation of transcription from RNA polymerase II promoter 1,29E-07 4,06E-02 18 42,00% GO:0051171 regulation of nitrogen compound metabolic process 4,83E-05 4,22E-02 18 42,00% GO:0019219 regulation of nucleobase-containing compound metabolic
process 3,98E-05 3,82E-02 17 40,00% GO:0044271 cellular nitrogen compound biosynthetic process 7,32E-07 4,98E-02 17 40,00% GO:0034654 nucleobase-containing compound biosynthetic process 3,84E-07 3,54E-02 17 40,00% GO:0019438 aromatic compound biosynthetic process 6,01E-07 4,49E-02 17 40,00% GO:0018130 heterocycle biosynthetic process 6,21E-07 4,56E-02 17 40,00% GO:0010468 regulation of gene expression 2,26E-05 2,87E-02 17 40,00% GO:0007389 pattern specification process 7,19E-07 4,41E-02 17 40,00% GO:0006351 transcription, DNA-templated 1,47E-08 4,14E-02 16 37,00% GO:1901362 organic cyclic compound biosynthetic process 9,77E-07 4,30E-02 16 37,00% GO:0051252 regulation of RNA metabolic process 6,37E-05 2,53E-02 16 37,00% GO:0010604 positive regulation of macromolecule metabolic process 2,80E-05 3,63E-02 15 35,00% GO:2001141 regulation of RNA biosynthetic process 9,00E-05 4,98E-02 15 35,00% GO:0048522 positive regulation of cellular process 1,76E-05 4,07E-02 15 35,00% GO:0045944 positive regulation of transcription from RNA polymerase II
promoter 3,50E-07 4,04E-02 15 35,00% GO:0045665 negative regulation of neuron differentiation 1,88E-07 4,43E-02 15 35,00% GO:0045664 regulation of neuron differentiation 6,31E-06 4,52E-02 15 35,00% GO:0010628 positive regulation of gene expression 2,09E-05 4,53E-02 15 35,00% GO:0009059 macromolecule biosynthetic process 2,54E-07 4,95E-02 15 35,00% GO:0006355 regulation of transcription, DNA-templated 7,54E-05 4,52E-02 15 35,00% GO:0003002 regionalization 1,96E-08 4,52E-02 14 33,00% GO:2000112 regulation of cellular macromolecule biosynthetic process 1,18E-04 4,28E-02 14 33,00% GO:0016070 RNA metabolic process 3,87E-07 2,62E-02 14 33,00% GO:0009893 positive regulation of metabolic process 9,20E-05 4,91E-02 14 33,00% GO:0000122 negative regulation of transcription from RNA polymerase II
promoter 1,72E-07 4,70E-02 13 30,00% GO:0090304 nucleic acid metabolic process 8,12E-06 4,40E-02 13 30,00% GO:0060255 regulation of macromolecule metabolic process 4,08E-04 4,91E-02 13 30,00% GO:0048518 positive regulation of biological process 8,29E-05 4,94E-02 13 30,00% GO:0010556 regulation of macromolecule biosynthetic process 1,83E-04 4,91E-02 12 28,00% GO:0048731 system development 6,08E-04 4,79E-02 12 28,00% GO:0045935 positive regulation of nucleobase-containing compound
metabolic process 1,18E-05 4,48E-02 12 28,00% GO:0045165 cell fate commitment 4,73E-07 2,45E-02 12 28,00% GO:0032502 developmental process 3,44E-07 3,27E-02 12 28,00% GO:0031326 regulation of cellular biosynthetic process 2,79E-04 2,82E-02
Bic (#) Bic (%) GO-term Descrizione P-value (min) P-value (max)
12 28,00% GO:0006366 transcription from RNA polymerase II promoter 2,36E-05 2,69E-02 11 26,00% GO:0080090 regulation of primary metabolic process 2,23E-04 3,83E-02 11 26,00% GO:0051960 regulation of nervous system development 7,20E-08 3,63E-02 11 26,00% GO:0051254 positive regulation of RNA metabolic process 9,88E-05 4,96E-02 11 26,00% GO:0051173 positive regulation of nitrogen compound metabolic process 1,46E-05 2,35E-02 11 26,00% GO:0050767 regulation of neurogenesis 1,40E-06 2,69E-02 11 26,00% GO:0045934 negative regulation of nucleobase-containing compound
metabolic process 3,81E-07 3,94E-02 11 26,00% GO:0031325 positive regulation of cellular metabolic process 1,10E-04 4,40E-02 11 26,00% GO:0031323 regulation of cellular metabolic process 1,94E-04 3,62E-02 10 23,00% GO:2000113 negative regulation of cellular macromolecule biosynthetic
process 3,20E-07 3,43E-02 10 23,00% GO:1902680 positive regulation of RNA biosynthetic process 8,93E-05 4,63E-02 10 23,00% GO:1902679 negative regulation of RNA biosynthetic process 1,10E-07 3,46E-02 10 23,00% GO:0060284 regulation of cell development 1,28E-05 4,58E-02 10 23,00% GO:0051253 negative regulation of RNA metabolic process 1,41E-07 4,01E-02 10 23,00% GO:0051172 negative regulation of nitrogen compound metabolic process 5,20E-07 3,63E-02 10 23,00% GO:0051094 positive regulation of developmental process 2,56E-05 4,63E-02 10 23,00% GO:0045893 positive regulation of transcription, DNA-templated 7,40E-05 4,06E-02 10 23,00% GO:0045892 negative regulation of transcription, DNA-templated 9,41E-08 3,14E-02 10 23,00% GO:0045597 positive regulation of cell differentiation 7,55E-05 4,21E-02 10 23,00% GO:0031328 positive regulation of cellular biosynthetic process 3,13E-04 4,93E-02 10 23,00% GO:0010629 negative regulation of gene expression 2,58E-07 2,87E-02 10 23,00% GO:0010558 negative regulation of macromolecule biosynthetic process 4,81E-07 4,75E-02 10 23,00% GO:0010557 positive regulation of macromolecule biosynthetic process 1,92E-04 3,12E-02 9 21,00% GO:1901576 organic substance biosynthetic process 2,14E-06 3,26E-02 9 21,00% GO:0048666 neuron development 9,54E-09 4,12E-02 9 21,00% GO:0048468 cell development 1,85E-08 3,43E-02 9 21,00% GO:0021879 forebrain neuron differentiation 2,76E-03 4,66E-02 9 21,00% GO:0009891 positive regulation of biosynthetic process 3,45E-04 3,05E-02 9 21,00% GO:0009887 organ morphogenesis 2,35E-05 4,95E-02 9 21,00% GO:0009653 anatomical structure morphogenesis 2,09E-06 4,21E-02 9 21,00% GO:0009058 biosynthetic process 3,03E-06 4,32E-02 8 19,00% GO:0048869 cellular developmental process 5,09E-06 2,35E-02 8 19,00% GO:0048598 embryonic morphogenesis 2,30E-08 2,90E-02 8 19,00% GO:0048562 embryonic organ morphogenesis 1,32E-03 3,27E-02 8 19,00% GO:0046483 heterocycle metabolic process 1,17E-04 4,92E-02 8 19,00% GO:0044767 single-organism developmental process 1,03E-06 1,19E-02 8 19,00% GO:0044249 cellular biosynthetic process 2,06E-05 2,29E-02 8 19,00% GO:0034645 cellular macromolecule biosynthetic process 7,77E-07 1,89E-02 8 19,00% GO:0009888 tissue development 3,55E-05 3,47E-02
Bic (#) Bic (%) GO-term Descrizione P-value (min) P-value (max)
7 16,00% GO:1901360 organic cyclic compound metabolic process 2,40E-04 2,61E-02 7 16,00% GO:0045596 negative regulation of cell differentiation 6,65E-04 4,98E-02 7 16,00% GO:0045168 cell-cell signaling involved in cell fate commitment 5,11E-03 3,92E-02 7 16,00% GO:0034641 cellular nitrogen compound metabolic process 1,99E-04 2,23E-02 7 16,00% GO:0031327 negative regulation of cellular biosynthetic process 4,02E-04 4,48E-02 7 16,00% GO:0030855 epithelial cell differentiation 3,84E-05 4,27E-02 7 16,00% GO:0009890 negative regulation of biosynthetic process 4,46E-04 4,75E-02 7 16,00% GO:0006725 cellular aromatic compound metabolic process 1,22E-04 1,49E-02 7 16,00% GO:0001568 blood vessel development 1,20E-04 2,44E-02 6 14,00% GO:0060429 epithelium development 5,86E-05 2,74E-02 6 14,00% GO:0060323 head morphogenesis 5,38E-03 1,78E-02 6 14,00% GO:0051093 negative regulation of developmental process 2,84E-03 3,75E-02 6 14,00% GO:0050793 regulation of developmental process 6,53E-03 3,62E-02 6 14,00% GO:0048856 anatomical structure development 3,56E-04 3,57E-02 6 14,00% GO:0048663 neuron fate commitment 1,37E-03 1,99E-02 6 14,00% GO:0045687 positive regulation of glial cell differentiation 5,10E-03 4,70E-02 6 14,00% GO:0045595 regulation of cell differentiation 6,26E-04 4,06E-02 6 14,00% GO:0021953 central nervous system neuron differentiation 1,46E-04 4,26E-02 6 14,00% GO:0021889 olfactory bulb interneuron differentiation 1,25E-03 3,84E-02 6 14,00% GO:0019222 regulation of metabolic process 1,23E-03 3,24E-02 6 14,00% GO:0010720 positive regulation of cell development 1,01E-03 4,05E-02 6 14,00% GO:0008284 positive regulation of cell proliferation 9,52E-05 1,88E-02 5 12,00% GO:0060021 palate development 1,66E-05 2,78E-02 5 12,00% GO:0050769 positive regulation of neurogenesis 5,05E-05 6,07E-03 5 12,00% GO:0048713 regulation of oligodendrocyte differentiation 1,33E-03 4,30E-02 5 12,00% GO:0048523 negative regulation of cellular process 1,51E-05 2,21E-02 5 12,00% GO:0048519 negative regulation of biological process 3,80E-05 3,67E-02 5 12,00% GO:0045931 positive regulation of mitotic cell cycle 1,85E-03 4,33E-02 5 12,00% GO:0044702 single organism reproductive process 8,10E-03 2,93E-02 5 12,00% GO:0044260 cellular macromolecule metabolic process 2,65E-03 3,62E-02 5 12,00% GO:0035137 hindlimb morphogenesis 1,82E-04 3,21E-02 5 12,00% GO:0031128 developmental induction 4,45E-03 3,42E-02 5 12,00% GO:0021780 glial cell fate specification 1,78E-03 1,98E-02 5 12,00% GO:0021778 oligodendrocyte cell fate specification 1,78E-03 1,98E-02 5 12,00% GO:0021545 cranial nerve development 4,90E-03 3,51E-02 5 12,00% GO:0021530 spinal cord oligodendrocyte cell fate specification 1,96E-04 6,17E-03 5 12,00% GO:0021522 spinal cord motor neuron differentiation 5,83E-03 2,76E-02 5 12,00% GO:0021515 cell differentiation in spinal cord 9,67E-04 4,43E-02 5 12,00% GO:0010975 regulation of neuron projection development 3,06E-04 1,48E-02 5 12,00% GO:0009954 proximal/distal pattern formation 1,02E-03 2,65E-02 5 12,00% GO:0007399 nervous system development 3,27E-04 2,49E-02 5 12,00% GO:0002009 morphogenesis of an epithelium 8,15E-08 4,92E-02 5 12,00% GO:0001764 neuron migration 7,34E-05 2,78E-02 5 12,00% GO:0001708 cell fate specification 4,65E-03 4,76E-02 4 9,00% GO:0060573 cell fate specification involved in pattern specification 1,51E-03 2,62E-02 4 9,00% GO:0048754 branching morphogenesis of an epithelial tube 8,17E-07 4,21E-02 4 9,00% GO:0048729 tissue morphogenesis 5,64E-09 2,23E-02 4 9,00% GO:0048714 positive regulation of oligodendrocyte differentiation 6,26E-03 2,11E-02 4 9,00% GO:0048608 reproductive structure development 2,62E-05 3,53E-02 4 9,00% GO:0045787 positive regulation of cell cycle 1,30E-02 3,40E-02 4 9,00% GO:0045685 regulation of glial cell differentiation 3,31E-03 3,92E-02 4 9,00% GO:0040007 growth 7,86E-07 2,15E-02 4 9,00% GO:0035148 tube formation 4,44E-03 2,41E-02
Bic (#) Bic (%) GO-term Descrizione P-value (min) P-value (max)
4 9,00% GO:0021884 forebrain neuron development 1,37E-05 4,47E-02 4 9,00% GO:0021675 nerve development 4,38E-03 2,54E-02 4 9,00% GO:0021521 ventral spinal cord interneuron specification 1,51E-03 2,62E-02 4 9,00% GO:0021516 dorsal spinal cord development 4,14E-03 4,75E-02 4 9,00% GO:0014015 positive regulation of gliogenesis 1,12E-02 2,85E-02 4 9,00% GO:0014013 regulation of gliogenesis 1,52E-03 3,00E-02 4 9,00% GO:0009968 negative regulation of signal transduction 4,08E-04 4,48E-02 4 9,00% GO:0009953 dorsal/ventral pattern formation 3,10E-11 2,13E-02 4 9,00% GO:0008285 negative regulation of cell proliferation 1,02E-03 5,01E-03 4 9,00% GO:0008283 cell proliferation 2,42E-04 4,37E-02 4 9,00% GO:0007498 mesoderm development 2,92E-04 5,23E-03 4 9,00% GO:0003281 ventricular septum development 6,81E-03 4,88E-02 4 9,00% GO:0003006 developmental process involved in reproduction 2,56E-04 1,73E-02 4 9,00% GO:0001822 kidney development 7,45E-04 3,40E-02 4 9,00% GO:0001501 skeletal system development 5,95E-05 4,51E-02 3 7,00% GO:2000026 regulation of multicellular organismal development 1,96E-03 3,50E-02 3 7,00% GO:0051726 regulation of cell cycle 9,47E-05 4,45E-02 3 7,00% GO:0050794 regulation of cellular process 8,63E-03 2,80E-02 3 7,00% GO:0048732 gland development 6,19E-05 4,43E-02 3 7,00% GO:0045666 positive regulation of neuron differentiation 1,35E-02 2,30E-02 3 7,00% GO:0042127 regulation of cell proliferation 6,88E-03 4,01E-02 3 7,00% GO:0035295 tube development 1,67E-04 1,96E-02 3 7,00% GO:0035108 limb morphogenesis 1,39E-04 2,41E-02 3 7,00% GO:0035107 appendage morphogenesis 1,39E-04 2,41E-02 3 7,00% GO:0032501 multicellular organismal process 1,25E-03 3,19E-02 3 7,00% GO:0031324 negative regulation of cellular metabolic process 2,09E-04 6,73E-03 3 7,00% GO:0031016 pancreas development 2,12E-03 4,98E-02 3 7,00% GO:0030856 regulation of epithelial cell differentiation 1,42E-02 1,95E-02 3 7,00% GO:0030177 positive regulation of Wnt signaling pathway 9,47E-03 2,84E-02 3 7,00% GO:0023057 negative regulation of signaling 6,57E-04 4,36E-02 3 7,00% GO:0021984 adenohypophysis development 8,04E-03 2,20E-02 3 7,00% GO:0021794 thalamus development 7,83E-03 4,11E-02 3 7,00% GO:0014070 response to organic cyclic compound 9,91E-04 4,82E-02 3 7,00% GO:0010648 negative regulation of cell communication 6,57E-04 4,43E-02 3 7,00% GO:0010647 positive regulation of cell communication 2,50E-03 2,96E-02 3 7,00% GO:0010605 negative regulation of macromolecule metabolic process 1,92E-04 6,16E-03 3 7,00% GO:0009967 positive regulation of signal transduction 1,49E-03 1,86E-02 3 7,00% GO:0009952 anterior/posterior pattern specification 7,88E-05 1,78E-02 3 7,00% GO:0009892 negative regulation of metabolic process 3,79E-04 1,26E-02 3 7,00% GO:0009267 cellular response to starvation 3,30E-03 4,83E-02 3 7,00% GO:0007275 multicellular organismal development 1,86E-02 3,59E-02 3 7,00% GO:0001763 morphogenesis of a branching structure 4,36E-06 3,40E-02 2 5,00% GO:2000179 positive regulation of neural precursor cell proliferation 3,10E-04 6,81E-03 2 5,00% GO:2000177 regulation of neural precursor cell proliferation 1,01E-04 5,15E-03 2 5,00% GO:1902751 positive regulation of cell cycle G2/M phase transition 1,61E-02 4,45E-02 2 5,00% GO:0097150 neuronal stem cell maintenance 1,46E-02 2,64E-02 2 5,00% GO:0072164 mesonephric tubule development 1,23E-02 4,60E-02 2 5,00% GO:0072148 epithelial cell fate commitment 3,31E-02 4,45E-02 2 5,00% GO:0071495 cellular response to endogenous stimulus 3,91E-04 2,31E-03 2 5,00% GO:0071363 cellular response to growth factor stimulus 1,99E-05 2,74E-02 2 5,00% GO:0070848 response to growth factor 3,11E-05 3,50E-02 2 5,00% GO:0061387 regulation of extent of cell growth 1,71E-03 3,66E-02 2 5,00% GO:0061138 morphogenesis of a branching epithelium 2,17E-06 2,29E-02
Bic (#) Bic (%) GO-term Descrizione P-value (min) P-value (max)
2 5,00% GO:0060411 cardiac septum morphogenesis 4,38E-04 9,57E-03 2 5,00% GO:0051090 regulation of sequence-specific DNA binding transcription
factor activity 3,06E-03 3,66E-02 2 5,00% GO:0050789 regulation of biological process 2,77E-02 4,78E-02 2 5,00% GO:0050770 regulation of axonogenesis 1,73E-03 2,71E-02 2 5,00% GO:0050768 negative regulation of neurogenesis 4,04E-02 4,80E-02 2 5,00% GO:0050678 regulation of epithelial cell proliferation 2,81E-02 4,99E-02 2 5,00% GO:0048863 stem cell differentiation 2,02E-03 2,44E-02 2 5,00% GO:0048711 positive regulation of astrocyte differentiation 1,29E-02 2,10E-02 2 5,00% GO:0048646 anatomical structure formation involved in morphogenesis 5,99E-03 2,67E-02 2 5,00% GO:0048638 regulation of developmental growth 3,96E-03 4,01E-02 2 5,00% GO:0048585 negative regulation of response to stimulus 2,44E-04 2,45E-03 2 5,00% GO:0048568 embryonic organ development 4,93E-04 3,06E-02 2 5,00% GO:0048538 thymus development 1,31E-02 4,87E-02 2 5,00% GO:0044707 single-multicellular organism process 1,06E-03 2,65E-02 2 5,00% GO:0043433 negative regulation of sequence-specific DNA binding
transcription factor activity 7,55E-04 5,36E-03 2 5,00% GO:0035329 hippo signaling 1,15E-02 1,30E-02 2 5,00% GO:0035136 forelimb morphogenesis 9,61E-04 1,04E-02 2 5,00% GO:0033993 response to lipid 3,55E-02 4,33E-02 2 5,00% GO:0032989 cellular component morphogenesis 1,80E-04 2,51E-04 2 5,00% GO:0031346 positive regulation of cell projection organization 9,76E-04 2,59E-03 2 5,00% GO:0031018 endocrine pancreas development 6,79E-03 4,59E-02 2 5,00% GO:0030857 negative regulation of epithelial cell differentiation 2,53E-02 3,67E-02 2 5,00% GO:0030516 regulation of axon extension 5,70E-04 1,61E-02 2 5,00% GO:0030325 adrenal gland development 7,98E-03 2,13E-02 2 5,00% GO:0022604 regulation of cell morphogenesis 1,55E-06 4,57E-02 2 5,00% GO:0022414 reproductive process 3,12E-02 4,74E-02 2 5,00% GO:0021983 pituitary gland development 8,03E-03 3,30E-02 2 5,00% GO:0021954 central nervous system neuron development 5,49E-07 1,52E-02 2 5,00% GO:0021798 forebrain dorsal/ventral pattern formation 3,00E-02 4,12E-02 2 5,00% GO:0021782 glial cell development 1,82E-03 1,04E-02 2 5,00% GO:0021555 midbrain-hindbrain boundary morphogenesis 1,65E-02 3,62E-02 2 5,00% GO:0016477 cell migration 9,28E-05 3,95E-02 2 5,00% GO:0014003 oligodendrocyte development 9,99E-03 2,89E-02 2 5,00% GO:0010971 positive regulation of G2/M transition of mitotic cell cycle 1,61E-02 4,45E-02 2 5,00% GO:0010721 negative regulation of cell development 1,20E-02 3,58E-02 2 5,00% GO:0009880 embryonic pattern specification 5,83E-04 7,24E-04 2 5,00% GO:0009790 embryo development 4,26E-03 4,25E-02 2 5,00% GO:0008589 regulation of smoothened signaling pathway 2,19E-05 3,33E-02 2 5,00% GO:0007507 heart development 4,45E-03 5,13E-03 2 5,00% GO:0007423 sensory organ development 1,15E-05 1,60E-02 2 5,00% GO:0007346 regulation of mitotic cell cycle 1,42E-03 3,84E-02 2 5,00% GO:0003323 type B pancreatic cell development 2,07E-02 2,79E-02 2 5,00% GO:0003279 cardiac septum development 8,21E-03 1,40E-02 2 5,00% GO:0001823 mesonephros development 3,48E-02 4,62E-02 2 5,00% GO:0001658 branching involved in ureteric bud morphogenesis 2,98E-04 3,09E-02 2 5,00% GO:0001657 ureteric bud development 8,25E-03 3,08E-02 2 5,00% GO:0001570 vasculogenesis 2,35E-05 3,76E-02 1 2,00% GO:2000648 positive regulation of stem cell proliferation 3,03E-03 3,03E-03 1 2,00% GO:2000027 regulation of organ morphogenesis 2,90E-03 2,90E-03 1 2,00% GO:1902749 regulation of cell cycle G2/M phase transition 2,10E-02 2,10E-02 1 2,00% GO:1902692 regulation of neuroblast proliferation 2,38E-02 2,38E-02
Bic (#) Bic (%) GO-term Descrizione P-value (min) P-value (max)
1 2,00% GO:1901342 regulation of vasculature development 1,31E-02 1,31E-02 1 2,00% GO:0097154 GABAergic neuron differentiation 2,22E-02 2,22E-02 1 2,00% GO:0090103 cochlea morphogenesis 4,47E-03 4,47E-03 1 2,00% GO:0080134 regulation of response to stress 3,53E-02 3,53E-02 1 2,00% GO:0072395 signal transduction involved in cell cycle checkpoint 4,94E-02 4,94E-02 1 2,00% GO:0072163 mesonephric epithelium development 1,36E-02 1,36E-02 1 2,00% GO:0072095 regulation of branch elongation involved in ureteric bud
branching
5,01E-03 5,01E-03 1 2,00% GO:0072091 regulation of stem cell proliferation 1,08E-02 1,08E-02 1 2,00% GO:0072089 stem cell proliferation 7,12E-03 7,12E-03 1 2,00% GO:0072073 kidney epithelium development 3,87E-02 3,87E-02 1 2,00% GO:0071504 cellular response to heparin 1,39E-02 1,39E-02 1 2,00% GO:0071503 response to heparin 2,14E-02 2,14E-02 1 2,00% GO:0071496 cellular response to external stimulus 3,50E-02 3,50E-02 1 2,00% GO:0071345 cellular response to cytokine stimulus 3,91E-02 3,91E-02 1 2,00% GO:0071000 response to magnetism 1,85E-03 1,85E-03 1 2,00% GO:0061351 neural precursor cell proliferation 2,98E-03 2,98E-03 1 2,00% GO:0061004 pattern specification involved in kidney development 4,66E-02 4,66E-02 1 2,00% GO:0060606 tube closure 6,83E-03 6,83E-03 1 2,00% GO:0060485 mesenchyme development 2,74E-02 2,74E-02 1 2,00% GO:0060415 muscle tissue morphogenesis 3,88E-02 3,88E-02 1 2,00% GO:0060253 negative regulation of glial cell proliferation 1,46E-02 1,46E-02 1 2,00% GO:0060251 regulation of glial cell proliferation 4,56E-02 4,56E-02 1 2,00% GO:0060174 limb bud formation 4,01E-02 4,01E-02 1 2,00% GO:0060164 regulation of timing of neuron differentiation 4,80E-02 4,80E-02 1 2,00% GO:0060023 soft palate development 7,32E-03 7,32E-03 1 2,00% GO:0051593 response to folic acid 2,96E-03 2,96E-03 1 2,00% GO:0051301 cell division 1,48E-02 1,48E-02 1 2,00% GO:0051240 positive regulation of multicellular organismal process 5,76E-04 5,76E-04 1 2,00% GO:0051239 regulation of multicellular organismal process 3,37E-02 3,37E-02 1 2,00% GO:0050877 neurological system process 4,90E-02 4,90E-02 1 2,00% GO:0050679 positive regulation of epithelial cell proliferation 3,24E-02 3,24E-02 1 2,00% GO:0048870 cell motility 1,98E-04 1,98E-04 1 2,00% GO:0048793 pronephros development 3,60E-02 3,60E-02 1 2,00% GO:0048715 negative regulation of oligodendrocyte differentiation 2,09E-02 2,09E-02 1 2,00% GO:0048710 regulation of astrocyte differentiation 3,99E-02 3,99E-02 1 2,00% GO:0048709 oligodendrocyte differentiation 4,57E-02 4,57E-02 1 2,00% GO:0048706 embryonic skeletal system development 1,31E-02 1,31E-02 1 2,00% GO:0048705 skeletal system morphogenesis 2,85E-02 2,85E-02 1 2,00% GO:0048665 neuron fate specification 7,48E-03 7,48E-03 1 2,00% GO:0048664 neuron fate determination 3,73E-02 3,73E-02 1 2,00% GO:0048589 developmental growth 8,88E-03 8,88E-03 1 2,00% GO:0048565 digestive tract development 3,63E-02 3,63E-02 1 2,00% GO:0048513 organ development 1,32E-02 1,32E-02 1 2,00% GO:0048483 autonomic nervous system development 2,63E-02 2,63E-02 1 2,00% GO:0048469 cell maturation 2,00E-02 2,00E-02 1 2,00% GO:0048286 lung alveolus development 4,14E-02 4,14E-02 1 2,00% GO:0045937 positive regulation of phosphate metabolic process 2,92E-02 2,92E-02 1 2,00% GO:0045927 positive regulation of growth 1,18E-02 1,18E-02 1 2,00% GO:0045683 negative regulation of epidermis development 4,81E-02 4,81E-02 1 2,00% GO:0045605 negative regulation of epidermal cell differentiation 2,35E-02 2,35E-02 1 2,00% GO:0045598 regulation of fat cell differentiation 1,05E-02 1,05E-02 1 2,00% GO:0044273 sulfur compound catabolic process 3,69E-02 3,69E-02
Bic (#) Bic (%) GO-term Descrizione P-value (min) P-value (max)
1 2,00% GO:0044087 regulation of cellular component biogenesis 1,05E-02 1,05E-02 1 2,00% GO:0043436 oxoacid metabolic process 4,86E-02 4,86E-02 1 2,00% GO:0043170 macromolecule metabolic process 1,69E-02 1,69E-02 1 2,00% GO:0043068 positive regulation of programmed cell death 1,05E-04 1,05E-04 1 2,00% GO:0043065 positive regulation of apoptotic process 9,94E-05 9,94E-05 1 2,00% GO:0043009 chordate embryonic development 1,06E-03 1,06E-03 1 2,00% GO:0042594 response to starvation 3,47E-02 3,47E-02 1 2,00% GO:0042476 odontogenesis 1,69E-02 1,69E-02 1 2,00% GO:0042472 inner ear morphogenesis 1,77E-03 1,77E-03 1 2,00% GO:0042327 positive regulation of phosphorylation 1,47E-02 1,47E-02 1 2,00% GO:0040011 locomotion 5,24E-04 5,24E-04 1 2,00% GO:0040008 regulation of growth 1,60E-02 1,60E-02 1 2,00% GO:0035883 enteroendocrine cell differentiation 2,28E-02 2,28E-02 1 2,00% GO:0035502 metanephric part of ureteric bud development 1,25E-02 1,25E-02 1 2,00% GO:0035113 embryonic appendage morphogenesis 4,29E-03 4,29E-03 1 2,00% GO:0034504 protein localization to nucleus 6,95E-03 6,95E-03 1 2,00% GO:0034097 response to cytokine 1,40E-02 1,40E-02 1 2,00% GO:0033273 response to vitamin 4,68E-02 4,68E-02 1 2,00% GO:0032870 cellular response to hormone stimulus 3,16E-02 3,16E-02 1 2,00% GO:0032808 lacrimal gland development 3,40E-02 3,40E-02 1 2,00% GO:0031669 cellular response to nutrient levels 2,53E-02 2,53E-02 1 2,00% GO:0031667 response to nutrient levels 5,31E-03 5,31E-03 1 2,00% GO:0031401 positive regulation of protein modification process 2,59E-02 2,59E-02 1 2,00% GO:0030901 midbrain development 1,62E-02 1,62E-02 1 2,00% GO:0030539 male genitalia development 2,79E-02 2,79E-02 1 2,00% GO:0030514 negative regulation of BMP signaling pathway 1,65E-02 1,65E-02 1 2,00% GO:0030326 embryonic limb morphogenesis 4,29E-03 4,29E-03 1 2,00% GO:0030099 myeloid cell differentiation 1,04E-02 1,04E-02 1 2,00% GO:0023051 regulation of signaling 4,14E-02 4,14E-02 1 2,00% GO:0022603 regulation of anatomical structure morphogenesis 2,13E-04 2,13E-04 1 2,00% GO:0022412 cellular process involved in reproduction in multicellular
organism 1,82E-03 1,82E-03 1 2,00% GO:0021930 cerebellar granule cell precursor proliferation 1,54E-02 1,54E-02 1 2,00% GO:0021924 cell proliferation in external granule layer 1,54E-02 1,54E-02 1 2,00% GO:0021846 cell proliferation in forebrain 4,39E-05 4,39E-05 1 2,00% GO:0021799 cerebral cortex radially oriented cell migration 2,41E-02 2,41E-02 1 2,00% GO:0021766 hippocampus development 3,30E-02 3,30E-02 1 2,00% GO:0021758 putamen development 4,64E-02 4,64E-02 1 2,00% GO:0021757 caudate nucleus development 4,64E-02 4,64E-02 1 2,00% GO:0021750 vestibular nucleus development 3,71E-03 3,71E-03 1 2,00% GO:0021700 developmental maturation 1,81E-03 1,81E-03 1 2,00% GO:0021549 cerebellum development 2,38E-02 2,38E-02 1 2,00% GO:0021546 rhombomere development 8,00E-05 8,00E-05 1 2,00% GO:0021534 cell proliferation in hindbrain 3,02E-02 3,02E-02 1 2,00% GO:0021510 spinal cord development 1,03E-02 1,03E-02 1 2,00% GO:0019752 carboxylic acid metabolic process 2,77E-02 2,77E-02 1 2,00% GO:0019230 proprioception 3,62E-02 3,62E-02 1 2,00% GO:0017015 regulation of transforming growth factor beta receptor signaling
pathway 4,99E-02 4,99E-02 1 2,00% GO:0010942 positive regulation of cell death 2,02E-04 2,02E-04 1 2,00% GO:0010941 regulation of cell death 3,55E-02 3,55E-02 1 2,00% GO:0010830 regulation of myotube differentiation 3,71E-02 3,71E-02 1 2,00% GO:0010769 regulation of cell morphogenesis involved in differentiation 3,04E-06 3,04E-06
Bic (#) Bic (%) GO-term Descrizione P-value (min) P-value (max)
1 2,00% GO:0010389 regulation of G2/M transition of mitotic cell cycle 1,94E-02 1,94E-02 1 2,00% GO:0009991 response to extracellular stimulus 9,20E-03 9,20E-03 1 2,00% GO:0009966 regulation of signal transduction 1,62E-02 1,62E-02 1 2,00% GO:0009950 dorsal/ventral axis specification 4,12E-02 4,12E-02 1 2,00% GO:0009798 axis specification 4,11E-03 4,11E-03 1 2,00% GO:0009792 embryo development ending in birth or egg hatching 1,26E-03 1,26E-03 1 2,00% GO:0009725 response to hormone 1,04E-02 1,04E-02 1 2,00% GO:0008593 regulation of Notch signaling pathway 3,88E-03 3,88E-03 1 2,00% GO:0008406 gonad development 2,78E-02 2,78E-02 1 2,00% GO:0007565 female pregnancy 2,54E-02 2,54E-02 1 2,00% GO:0007420 brain development 4,67E-04 4,67E-04 1 2,00% GO:0007417 central nervous system development 3,97E-05 3,97E-05 1 2,00% GO:0007154 cell communication 1,65E-02 1,65E-02 1 2,00% GO:0006629 lipid metabolic process 8,89E-03 8,89E-03 1 2,00% GO:0006461 protein complex assembly 2,16E-02 2,16E-02 1 2,00% GO:0003156 regulation of organ formation 1,05E-02 1,05E-02 1 2,00% GO:0003151 outflow tract morphogenesis 2,81E-02 2,81E-02 1 2,00% GO:0002070 epithelial cell maturation 7,88E-03 7,88E-03 1 2,00% GO:0002068 glandular epithelial cell development 4,60E-02 4,60E-02 1 2,00% GO:0002064 epithelial cell development 3,51E-04 3,51E-04 1 2,00% GO:0002052 positive regulation of neuroblast proliferation 3,19E-02 3,19E-02 1 2,00% GO:0001843 neural tube closure 6,53E-03 6,53E-03 1 2,00% GO:0001709 cell fate determination 4,16E-02 4,16E-02 1 2,00% GO:0001701 in utero embryonic development 9,51E-04 9,51E-04 1 2,00% GO:0001654 eye development 8,45E-03 8,45E-03 1 2,00% GO:0001569 patterning of blood vessels 1,93E-04 1,93E-04 1 2,00% GO:0000902 cell morphogenesis 1,54E-02 1,54E-02