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Introduction to the ACM TIST Special Issue on Intelligent Healthcare

Informatics

CARLO COMBI, Universit `a degli Studi di Verona

JIMING LIU, Hong Kong Baptist University

ACM Reference Format:

Carlo Combi and Jiming Liu, 2015. Introduction to the ACM TIST Special Issue on Intelligent Healthcare Informatics. ACM Trans. Intell. Syst. Technol. V, N, Article A (January YYYY), 4 pages.

DOI:http://dx.doi.org/10.1145/0000000.0000000

1. INTRODUCTION

Healthcare Informatics is a research area dealing with the study and application of computer science and information and communication technology to face both theo-retical/methodological and practical issues in healthcare, public health, and everyday wellness. Intelligent Healthcare Informatics may be defined as the specific area focus-ing on the use of artificial intelligence (AI) theories and techniques to offer important services (such as a component of complex systems) to allow integrated systems to per-ceive, reason, learn, and act intelligently in the healthcare arena. One of the many peculiarities of healthcare is that decision support systems need to be integrated with several heterogeneous systems supporting both collaborative work and process coordi-nation and the management and analysis of a huge amount of clinical and health data, to compose intelligent, process-aware health information systems.

After some pioneering work focusing explicitly on specific medical aspects and pro-viding some efficient, even ad hoc, solutions, in recent years AI in healthcare has been faced by researchers with different backgrounds and interests, taking into consider-ation the main results obtained in the more general and theoretical/methodological area of intelligent systems. Moreover, from a focus on reasoning strategies and deep knowledge representation, research in healthcare intelligent systems moved to data-intensive clinical tasks, where there is the need of supporting healthcare decision making in the presence of overwhelming amounts of clinical data. Significant solu-tions have been provided through a multidisciplinary combination of the results from the different research areas and their associated cultures, ranging from algorithms, to information systems and databases, to human-computer interaction, to medical formatics. To this regard, it is interesting to observe that, from one side, medical in-formaticians benefitted by the general solutions coming from the generic computer science area, tailoring them to specific medical domains, while, from the other side, computer scientists found several (still open) challenges in the medical and, more gen-erally, health domains.

Author’s addresses: C. Combi, Dipartimento di Informatica, Universit `a degli Studi di Verona, strada le Grazie 15, I-37134 Verona, Italy, e-mail: carlo.combi@univr.it; J. Liu, Department of Computer Science, Hong Kong Baptist University, Kowloon Tong, Hong Kong, e-mail: jiming@comp.hkbu.edu.hk

Permission to make digital or hard copies of part or all of this work for personal or classroom use is granted without fee provided that copies are not made or distributed for profit or commercial advantage and that copies show this notice on the first page or initial screen of a display along with the full citation. Copyrights for components of this work owned by others than ACM must be honored. Abstracting with credit is per-mitted. To copy otherwise, to republish, to post on servers, to redistribute to lists, or to use any component of this work in other works requires prior specific permission and/or a fee. Permissions may be requested from Publications Dept., ACM, Inc., 2 Penn Plaza, Suite 701, New York, NY 10121-0701 USA, fax +1 (212) 869-0481, or permissions@acm.org.

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YYYY ACM 2157-6904/YYYY/01-ARTA $15.00 DOI:http://dx.doi.org/10.1145/0000000.0000000

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This ACM Transactions on Intelligent Systems and Technology (ACM TIST) special issue contains articles discussing fundamental principles, algorithms or applications for process-aware health information systems. Such papers are a sound answer to to the research challenges for novel techniques, combinations of tools, and so forth to build effective ways to manage and deal in an integrated way with healthcare pro-cesses and data.

2. THE PAPERS OF THIS SPECIAL ISSUE

The current special issue is composed by eight research papers. The first two papers deal with smart homes, as they are of high interest in the next (and current) health-care scenario, where the right specific health-care services are provided at home as much as possible.

The first paper, entitled “Analyzing Activity Recognition Uncertainties in Smart Home Environments”, deals with an emerging important topic in the area of health-care informatics. Indeed, activity recognition (AR) for intelligent human computer in-teraction is a critical aspect in many smart home applications supporting elderly, pa-tients with chronic diseases, or people with special needs. However, state-of-the-art AR technology is not ready or adequate for real world deployments due to its insuffi-cient accuracy. Here, the authors propose an approach, which can account for multiple uncertainty sources and assess their impact on AR systems.

The paper entitled “Design of a Predictive Scheduling System to Improve Assisted Living Services for Elders” describes a system assisting caregivers to work in geriatric residences. From this study, the authors obtained relevant requirements and insights of design that were used to design, implement and evaluate two prototypes for sup-porting caregivers’ tasks (e.g. electronic recording and automatic notifications). PRES-ENCE, the predictive schedule system proposed, triggers real-time alerts of risky sit-uations from sensors (e.g. falls, entering off-limits areas such as the infirmary or the kitchen) and informs caregivers of routine tasks that need to be performed (e.g. medi-cation administration, diaper change, etc.).

The web is nowadays an extremely powerful way of accessing healthcare informa-tion and recommendainforma-tions. However the overwhelming amount of data at disposal may generate frustration and/or use of low-quality sources. In this direction, the paper entitled “Empowering Patients and Caregivers to Manage Healthcare via Streamlined Presentation of Web Objects Selected by Modeling Learning Benefits Obtained by Sim-ilar Peers” introduces a framework for selecting web objects (texts, videos, and simu-lations) from a large online repository to present to patients and caregivers, in order to assist in their healthcare. The authors are motivated by the paradigm of peer-based intelligent tutoring, and model the learning gains achieved by users when exposed to specific web objects. They show that streamlined presentations lead to effective knowl-edge gains, for the specific application of caring for children with autism.

Data and text mining in healthcare and medicine are attracting several research efforts, in the direction of both (i) supporting decisions in the clinical domain, such as diagnosis, therapy, and patient monitoring, (ii) extending and deriving new med-ical knowledge, and (iii) supporting healthcare activities as drug safety surveillance and pandemic monitoring. In the healthcare domain, the authors of the paper entitled “Using Health Consumer Contributed Data to Detect Adverse Drug Reactions by Asso-ciation Mining with Temporal Analysis” propose to use assoAsso-ciation mining to identify relations between a drug and an adverse drug reaction and temporal analysis to de-tect drug safety signals at the early stage. Web based data sources are in this case health-related social media and the proposed techniques are effective to identify early adverse reaction signals.

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Special Issue on Intelligent Healthcare Informatics A:3

The huge amount of clinical and health data available makes extremely interesting the issue of providing physicians with data-centric decision-support tools in diagnosis, therapy, and patient monitoring. The proposal of suitable data mining techniques is the focus of the paper entitled “Estimating a Ranked List of Human Genetic Diseases by Associating Phenotype-Gene with Gene-Disease Bipartite Graphs”. Here, authors propose a method for ranking genetic diseases for a set of clinical phenotypes through weighted bipartite graphs.

In the paper entitled “MeTA: Characterization of Medical Treatments at Different Abstraction Levels”, the authors deal with the extraction of association rules at dif-ferent levels of abstraction, by considering taxonomies for drugs and examinations, from patient datasets. Considered data are prescribed examinations, drugs, and pa-tient profiles. The effectiveness of the proposed approach has been experimented on a real diabetic patient dataset.

Finally, in the paper entitled “Smart Colonography for Distributed Medical Databases with Group Kernel Feature Analysis”, the authors face the problem of computer-aided detection (CAD) of polyps in Computed Tomographic (CT) colonogra-phy, As currently single databases at each hospital/institution do provide enough data for training the classification algorithm, the use of multiple distributed databases is proposed, together wih a scalable and efficient algorithm, which can be applied to mul-tiple cancer databases to improve the overall performance of CAD.

Moving to the sound topic of natural language processing for healthcare applica-tions, in the paper “Recognition of Patient-related Named Entities in Noisy Tele-health Texts”, the authors investigate the application of state of the art natural language pro-cessing and machine learning to clinical narratives to extract meaningful information. The considered (noisy) data consists of dialogues transcribed by nurses while consult-ing patients by phone. The authors propose then ad-hoc techniques to filter different kinds of noise in the data. The result of this de-noising task is the extraction of normal-ized patient information, visualnormal-ized as a graph made of linked named entities, where term associations and trends of patients symptoms and concern are highlighted.

3. CONCLUDING REMARKS

Building a special issue is always an interesting and intensive activity. After the proval by the Editor in Chief of the Journal in October 2012, the call for papers ap-peared (disseminated since the autumn of 2012, through internet announcements, and through specific mailing lists for people working in the areas of artificial intelligence and healthcare informatics), and by the end of November 2013 we received 31 submit-ted papers. Two further regular papers submitsubmit-ted for publication in ACM TIST have been managed by the guest editors, to evaluate its inclusion in this special issue. Each submitted manuscript has been refereed usually by three reviewers, chosen to have both medical and technical expertise on the topic of the manuscript. Further revisions and review phases followed for potentially accepted papers. Eventually, we selected 8 research papers from 33 submissions (with an acceptance rate of about 24%). Papers were selected according to several interdisciplinary criteria. In particular, reviewers evaluated papers with respect to both the methodological and/or theoretical contents and the relevance to the considered clinical domains. Thus, authors were required to demonstrate that their research results are both technically sound in methodology and relevant in the healthcare arena.

ACKNOWLEDGMENTS

We are grateful to the authors who submitted their original contributions, and to our colleagues who care-fully reviewed (often multiple revisions of) the submissions and provided authors with their valuable

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ments and suggestions. We are also grateful to the ACM TIST Editors in Chief, Prof. Qiang Yang and Prof. Huan Liu, for having enthusiastically approved and supported the preparation of this special issue. A spe-cial thanks is due to Weike Pan, who helped us in any organizational step needed to build such a spespe-cial issue.

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