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La termodiluizione transpolmonare e i volumi in Anestesia e Rianimazione

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(1)CORSO TEORICO-PRATICO NAPOLI 9-10 GIUGNO 2005. La Termodiluizione Transpolmonare ed I Volumi in Anestesia e Rianimaizone Prof Giorgio Della Rocca Clinica di Anestesia e Rianimazione APUGD (Azienda Policlinico Universitario a Gestione Diretta). University of Udine. Udine, Italy.

(2) Iced Versus Room Temperature Injectate for Assessment of Cardiac Output, Intrathoracic Blood Volume, and Extravascular lung Water by Single Transpulmonary Thermodilution P Faybik, H Hetz, A Baker, E Yankovskaya, CG Krenn andf H Steltzer. Septic shock. 8. 15 critically ill pts. Pancreatitis. 2. Acute liver failure. 2. Surgical Intensive Care Unit. OLTx. 1. PiCCO System Triplicate STPD with a 20 mL of Room Temperature and iced saline solution. J Crit Care 2004; 19(2):103-7.

(3) CI r=0.95 bias -0.2 2SD 0.7 L min-1 m-2. 144 data pairs. ITBVI r=0.91 bias -4.9 2SD 194 mL m-2. EVLWI r=0.97 bias -0.535 2SD 1.5 mL kg-1. J Crit Care 2004; 19(2):103-7.

(4) Reliability of a new algorithm for continuous cardiac output determination by pulse-contour analysis during hemodynamic instability O Godje, K Hoke, AE Goetz, TW Felbinger, DA Reuter, B Reichart, R Frield, A Hannekum, UJ Pfeiffer. Wesseling Algorithm. CO. = HR ·. PCnew. New Algorithm. Asys/Zao. Where Zao = SVpc/SVtd. Crit Care Med 2002; 30(1): 52-8.

(5) Wesseling Algorithm. New Algorithm. Crit Care Med 2002; 30(1): 52-8.

(6) Reliability of a new algorithm for continuous cardiac output determination by pulse-contour analysis during hemodynamic instability O Godje, K Hoke, AE Goetz, TW Felbinger, DA Reuter, B Reichart, R Frield, A Hannekum, UJ Pfeiffer. CONCLUSIONS Pulse contour cardiac output measurements provides an easy and reliable method for the continuous monitoring of cardiac output in critically ill patients.. Crit Care Med 2002; 30(1): 52-8.

(7) Intra Thoracic Blood Volume: preload?. ITBV. ITBV. =. TBV. 3. ITBV = 1.25*GEDV. Clinical application-Preload.

(8) Preload index: PAOP versus intrathoracic blood volume monitoring during lung transplantation G Della Rocca, MG Costa, C Coccia, L Pompei, P Di Marco, P Pietropaoli. r2= 0.41 p<0.0001. r2= - 0.01 ns 40. PAOP (mmHg). ITBVI (mL m -2). 1500. 1000. 500. 30. 20. 10. 0. 0 0. 10. 20. 30. 40. 50. SVIpa (mL m -2). 60. 70. 80. 0. 10. 20. 30. 40. 50. 60. 70. 80. SVIpa (mL m -2). Anesth Analg 2002; 95: 835-43.

(9) ITBVI: misinterpretations. • Huge aneurismatic lesions strongly increase ITBVI • ITBV indicates the amount of “central blood” and you have to give a clinical meaning in “that” patient (i. e. ITBVI = 1600 ml/m2: hyperdinamic state or cardiac failure?).

(10) Prognostic Values of Extravascular Lung Water in Critically Ill patients SG Sakka, M Klein, K Reinhart, A Meier-Hellman. EVLW was significantly higher in NS than in S 15.6±7.8ml/kg [median, 14.3] vs 12.2±6.4ml/kg [median 10.2] Chest 2002; 122:2080-2086.

(11) Extravascular lung water in patients with severe sepsis: a prospective cohort study GS Martin, S Eaton, M Mealer, M Moss. 1. The majority of severe sepsis pts have increased amounts of EVLW including those who do not meet clinical criteria definig ARDS 2. Increased EVLW is associated with worse survival in patients with severe sepsis and viceversa 3. Chronic. alcohol. quantities. of. abuse EVLW. is. associated. with. increased. (alveolar-capillary. barrier. dysfunction?). Critical Care 2005; 9(2):R74-R82.

(12) SVV:. The percentage of variations among the. max and the min Stroke Volumes on the mean of the min and the max during 12 sec of measure. AP. Stroke volume variation. t.

(13) Pulse pressure variation. (PPV). ∆PP(%)=100*[(PPmax-PPmin)/(PPmax+PPmin)]:2 PP= APsyst - APdiast. PP.

(14) Assessing fluid-responsiveness by a standardized ventilatory maneuver: The respiratory systolic variation test A Perel, L Minkovich, S Preisman, M Abiad, E Segal, P Coriat. Schematic representation of the respiratory Systolic Variation Test (RSVT) maneuver. The smallest 4 systolic pressure values (identified by the x) are plotted against their respective airway pressures to obtain the slope of the RSVT (mmHg/cmH20).. Anesth Analg 2005; 100: 942-5.

(15) Assessing fluid-responsiveness by a standardized ventilatory maneuver: The respiratory systolic variation test A Perel, L Minkovich, S Preisman, M Abiad, E Segal, P Coriat. 1. The AUC (ROC) for a ≥15 change of CI: PAOP = 0.771 (95% CI, 0.486-1.055), EDAI = 0.875 (95% CI, 0.6831.067), and RSVT = 0.896 (95% CI, 0.726-1.065) 2. RSVT value ≥ 0.24 mmHg/cmH2O predicted a change ≥15% in CI with a sensitivity of 87.5% and a specificity of 83%. 3. EDAI value≤10.2 cm2/m2 predicted a change ≥15% in CI with a sensitivity of 87.5% and a specificity of 67%. Anesth Analg 2005; 100: 942-5.

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