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Home Long-Term Oxygen Treatment in Italy

The Additional Value of Telemedicine

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R.W. Dal Negro • A.I. Goldberg (Eds)

Home Long-Term Oxygen Treatment in Italy

The Additional Value of Telemedicine

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R.W. DAL NEGRO, MD, FCCP Lung Department

Bussolengo General Hospital Bussolengo (Verona), Italy Vice-President

Italian Society of Respiratory Medicine (SIMeR) A.I. GOLDBERG, MD, MBA, FAAP, FACPE, Master FCCP Professor of Pediatrics

Loyola University Chicago, USA

Past-President, American College of Chest Physicians Past-President, American Academy of Home Care Physicians

The Editors and Authors wish to thank Italia Spa, in particular Dr. Roberto Erba, for their contribution to this book

Library of Congress Control Number: 2005934784

ISBN 10 88-470-0388-1 Springer Milan Berlin Heidelberg New York ISBN 13 978-88-470-0388-0

This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcast- ing, reproduction on microfilm or in any other way, and storage in data banks. Duplication of this pub- lication or parts thereof is permitted only under the provisions of the Italian Copyright Law in its cur- rent version, and permission for use must always be obtained from Springer. Violations are liable to prosecution under the Italian Copyright Law.

Springer is a part of Springer Science+Business Media springeronline.com

© Springer-Verlag Italia 2005 Printed in Italy

The use of general descriptive names, registered names, trademarks,etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant pro- tective laws and regulations and therefore free for general use.

Product liability: The publishers cannot guarantee the accuracy of any information about dosage and application contained in this book. In every individual case the user must check such information by consulting the relevant literature.

Cover design: Massimiliano Caleffi Typesetting: Marco Lorenti Printing: Lineadue, Marnate (VA)

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Preface

As an American, I recently began extending visits to friends in Italy by meeting families providing “agriturismo”. My Italian speaking wife Evi (Eveline Faure, MD, FCCP, a graduate of the Università Italiana per Stranieri, Perugia) made this pos- sible.

During one visit in 1994, we were sitting around the table in Pisa with friends who were fellow critical care physicians. They were remarking how specialists needed more patients. We told them that we were going south beyond Naples, a concept which they could not understand, considering the beauty of Tuscany. We had a marvelous time in southern Italy, meeting warm and welcoming people, surely one of the greatest resources of all Italy.

While in Calabria, I noted there were so many people on the streets joyfully communicating on their cell phones. (This was before cellular technology became so popular in the USA). Evi commented how tele-communication had advanced in Italy; she remembered how it took three hours to make a phone call with a jetton only a few years before. Later, in a small town (Revello, Basilicata), we met a won- derful young family who told us how difficult it was to get medical care. Yes, they had good general physicians, but it was hard to reach specialists many kilometers away. At the time, we were staying on a farm with an elderly couple, who invited us to join them to share meals. During conversation, I learned that the farmer had chronic lung disease and required long-term oxygen. He, too, found it difficult to get the care he needed in rural Italy.

I started to think… specialists up North, need in the South … why not connect by tele-communication??

Many years later, I was introduced to telemedicine. As I traced its world-wide evolution, I was given a trade association report (un-authored) about a well-estab- lished program in Verona that used telemedicine for long-term oxygen manage- ment of chronic respiratory illness. I included this observation during a Memorial Lecture to honor the late Luciano Pesce, MD, FCCP, in Padua several years later. In the audience sat a gentleman who smiled as I did. Later, he introduced himself to me as Roberto Dal Negro, MD, FCCP. He humbly noted to me that he was grateful that I have acknowledged his team’s work in Verona!

I have followed with admiration the work of Dott. Dal Negro and colleagues in

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Veneto ever since. Their extensive experience with outcome analysis is an impor- tant demonstration of the value of telemedicine in home care. It would interest all those involved with long-term care for chronic illness (physicians, patients and families, health care organizations and funders, public policy leaders etc.) in Italy and elsewhere. This book is an effort to extend the awareness of their major accomplishment so all can understand the benefit to patients and families around the world.

Allen I. Goldberg Professor of Pediatrics Loyola University Chicago, USA Past-President, American College of Chest Physicians Past-President, American Academy of Home Care Physicians VI

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Contents

Preface... V

Introduction ... 1

Telemedicine in Respiratory Care ... 3

A.I. Goldberg A FUTUREVISION FOR THEUSE OFTELEMEDICINE INRESPIRATORYCARE ... 3

WHAT IS“TELEMEDICINE” (E-HEALTH)? ... 3

THEPAST: HOW HASTELEMEDICINEBEENUSEDRECENTLY TOPROVIDE RESPIRATORYCARE? ... 4

THEPRESENT: WHAT IS THECURRENTEVIDENCE FOR THEVALUE OFTELEMEDICINE? ... 6

WHAT ARE THECURRENTTRENDS TOCONSIDER FOR THEFUTURE OFHEALTHCARE? ... 7

THEVISION: A PREFERREDSCENARIO FOR THEFUTURE... 10

GLOBALHEALTHVISION FORTELEMEDICINE AND E-HEALTH... 11

A CALL FORDESCRIPTIVEEXPERIENCE AND FOROUTCOME-BASED EVALUATIONRESEARCH ... 13

Home Long-Term Oxygen Treatment (H-LTOT): Why, Where, and How... 15

R.W. Dal Negro From National to Regional Criteria for H-LTOT ... 27

F. Facchini, F. Trevisan OXYGEN ASMEDICATION... 27

WHOCANDELIVEROXYGEN INITALY: OXYGEN ASMEDICATION ANDH-LTOT ASSERVICE ... 27

TEMPORARYOXYGENDELIVERY ... 28

HOMELONG-TERMOXYGENTREATMENT... 28

LTOT WITHCONTINUOUSUSE... 28

LTOT WITHINTERMITTENTUSE... 29

NOCTURNALH-LTOT USE... 30

PALLIATIVEINDICATIONS... 31

HOW TOMEASUREOXYGENNEEDS: FLOW ANDDURATION ... 31

FROMNATIONAL TOREGIONALCRITERIA... 31

CONCLUSIONS... 38

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Systems for Oxygen Delivery ... 43

E. Battaglia, S. Amaducci HIGHPRESSURECYLINDERS(GASEOUSOXYGEN) ... 43

LIQUIDOXYGENSYSTEMS(CRYOGENICRESERVETANKS) ... 47

OXYGENCONCENTRATORS ... 55

The Interfaces ... 59

S. Amaducci, E. Battaglia NASALCANNULAE... 59

SIMPLEFACIALOXYGENMASKS... 61

RESERVOIRFACIALMASKS... 62

VENTURIFACIALMASKS ... 62

NASALCATHETERS ... 63

TRANSTRACHEALOXYGENTHERAPY... 63

OXYGENECONOMIZERS ... 65

OXYGENDEVICES FORTRACHEOSTOMY ... 66

Telemedicine and LTOT in Italy: a 20-Year Experience ... 69

R.W. Dal Negro, P. Turco New Telemonitoring Technologies in Italy... 85

C. Guglielmetti, M. Gaiani ALS CON-TELII ... 85

ALS GATE... 89

The Changing Role of Nursing in Telemetric LTOT at Home ... 95

R. Bisato, C. Turati Home LTOT: Patient–Caregiver Compliance and Adhesion ... 101

P. Pescatori, R. Cadinu Complications in LTOT patients ... 109

C. Micheletto, R.W. Dal Negro PULMONARYHYPERTENSION AS ACOMPLICATION OFCOPD PATIENTS DURINGLTOT ... 109

CLOTTING ANDTHROMBOSIS INCOPD DURINGLTOT ... 111

CHRONICRESPIRATORYFAILURE... 111

ACUTEEXACERBATIONS... 112

SLEEPDISORDERS ... 113

NEUROPSYCHOLOGICEFFECTS OFHYPOXIA... 114

NUTRITIONALDEPLETION INPATIENTS ONLTOT ... 114

HAZARDS OFHOMEOXYGENTHERAPY ... 115

LTOT Outcomes: Patient’s and Doctor’s Perspectives ... 119

S. Tognella EFFECT OFLONG-TERMOXYGENTHERAPY ONMORTALITY ... 120

EFFECT OFLONG-TERMOXYGENTHERAPY ONPULMONARYHAEMODYNAMICS... 122

EFFECT OFLONG-TERMOXYGENTHERAPY ONSLEEP ... 124 VIII

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EFFECT OFLONG-TERMOXYGENTHERAPY ONEXERCISEPERFORMANCE... 125

EFFECT OF LONG-TERMOXYGENTHERAPY ONCOGNITIVE-NEUROLOGICAL DYSFUNCTION AND ONQUALITY OFLIFE... 126

EFFECT OFLONG-TERMOXYGENTHERAPY ONHOSPITALISATION ... 127

EFFECT OFLONG-TERMOXYGENTHERAPY ONNUTRITIONALSTATUS... 129

Telemedicine for Home-Ventilated Patients ... 133

E.E. Guffanti, D. Colombo, A. Fumagalli, C. Misuraca, A. Viganò MECHANICALVENTILATION... 133

TELEMEDICINE ANDVENTILATION ATHOME ... 134

WHAT IS ITUSEFUL TOMONITOR? ... 135

SYSTEMS OFMONITORING ... 135

OUREXPERIENCE... 137

CHARACTERISTICS OF THENEWSYSTEM... 138

EVOLUTION OF THEEXPERIENCE... 140

LIMITS ANDADVANTAGES OF THESYSTEM... 142

TELEMEDICINE INHOME-VENTILATEDPATIENTS:THEPRESENT AND THEFUTURE... 144

LEGALPROBLEMS... 145

Economic Evaluation of Treating Patients with Long-Term Oxygen Therapy with or without Telemetric Monitoring ... 147

R. Ravasio, R.W. Dal Negro, C. Lucioni INTRODUCTION... 147

MATERIAL ANDMETHODS ... 147

RESULTS... 147

CONCLUSION ... 150

Continuing Quality Improvement in the Management of H-LTOT ... 151

M. Farina, S. Tognella QUALITY ANDITSEVOLUTION IN THEINTERNATIONALARENA... 151

THEEVOLUTION OF THECONCEPT OFQUALITY INITALY... 152

THEISO 9001:2000 MODEL ANDITSRELEVANCE TOPNEUMOLOGY ... 154

PROCESSAPPROACH ANDMANAGEMENT AS ABASIS FOR THEORGANISATION OF AHOME-BASEDOXYGENTHERAPYSERVICE ... 157

IX

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Contributors

S. AMADUCCI

Department of Pneumology San Carlo Borromeo Hospital Milan, Italy

E. BATTAGLIA

Department of Pneumology San Carlo Borromeo Hospital Milan, Italy

R. BISATO Lung Department

Bussolengo General Hospital Bussolengo (Verona), Italy

R. CADINU Lung Department

Bussolengo General Hospital Bussolengo (Verona), Italy

D. COLOMBO

Respiratory Department Pulmonary Rehabilitation Unit INRCA - Scientific Institute Casatenovo (Lecco), Italy

R.W. DALNEGRO Lung Department

Bussolengo General Hospital Bussolengo (Verona), Italy

F. FACCHINI Lung Department

Bussolengo General Hospital Bussolengo (Verona), Italy

M. FARINA

EmmeEffe, Management & Formazione Milan, Italy

A. FUMAGALLI Respiratory Department Pulmonary Rehabilitation Unit INRCA - Scientific Institute Casatenovo (Lecco), Italy

M. GAIANI

IT Business Department, ALS VitalAire Spa

Milan, Italy

A.I. GOLDBERG Professor of Pediatrics Loyola University Chicago, USA

E.E. GUFFANTI Respiratory Department Pulmonary Rehabilitation Unit INRCA - Scientific Institute, Casatenovo (Lecco), Italy

C. GUGLIELMETTI

IT Business Department, ALS VitalAire Spa

Milan, Italy

C. LUCIONI

Wolters Kluwer Health Adis International ltd.

Milan, Italy

C. MICHELETTO Lung Department

Bussolengo General Hospital Bussolengo (Verona), Italy

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C. MISURACA

Respiratory Department Pulmonary Rehabilitation Unit INRCA - Scientific Institute Casatenovo (Lecco), Italy

P. PESCATORI Lung Department

Bussolengo General Hospital Bussolengo (Verona), Italy

S. TOGNELLA Lung Department

Bussolengo General Hospital Bussolengo (Verona), Italy

F. TREVISAN Lung Department

Bussolengo General Hospital Bussolengo (Verona), Italy

C. TURATI Lung Department

Bussolengo General Hospital Bussolengo (Verona), Italy

P. TURCO

PhD, University of Milan, Italy

R. RAVASIO

Wolters Kluwer Health Adis International ltd.

Milan, Italy

A. VIGANÒ Informatic Engineer

Cassano Magnano, Varese, Italy XII

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