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Italy Tuberculosis profile

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Italy Tuberculosis profile

Population 2017 59 million

Estimates of TB burden*, 2017 Number (thousands) Rate

(per 100 000 population) Mortality (excludes HIV+TB) 0.34 (0.33–0.34) 0.57 (0.56–0.58) Mortality (HIV+TB only) 0.072 (0.036–0.12) 0.12 (0.06–0.21) Incidence (includes HIV+TB) 4.4 (3.8–5.1) 7.4 (6.3–8.6) Incidence (HIV+TB only) 0.47 (0.27–0.72) 0.79 (0.46–1.2) Incidence (MDR/RR-TB)** 0.18 (0.11–0.25) 0.3 (0.19–0.43) Estimated TB incidence by age and sex (thousands)*, 2017

0-14 years > 14 years Total

Females 0.16 (0.13–0.2) 1.3 (1–1.5) 1.4 (1.1–1.7)

Males 0.19 (0.15–0.23) 2.8 (2.2–3.4) 3 (2.4–3.6)

Total 0.36 (0.3–0.42) 4 (3.4–4.7) 4.4 (3.8–5.1)

TB case notifications, 2017

Total cases notified 3 944

Total new and relapse 3 828

- % tested with rapid diagnostics at time of diagnosis 0%

- % with known HIV status

- % pulmonary 70%

- % bacteriologically confirmed among pulmonary 80%

Universal health coverage and social protection

TB treatment coverage (notified/estimated incidence), 2017 87% (75–100) TB patients facing catastrophic total costs

TB case fatality ratio (estimated mortality/estimated incidence), 2017 0.09 (0.08–0.11)

TB/HIV care in new and relapse TB patients, 2017 Number (%)

Patients with known HIV-status who are HIV-positive - on antiretroviral therapy

Drug-resistant TB care, 2017 New cases Previously treated cases

Total number***

Estimated MDR/RR-TB cases among notified pulmonary TB cases

91 (59–120) Estimated % of TB cases with MDR/RR-TB 2.8% (1.8–4.3) 13% (7.7–21)

% notified tested for rifampicin resistance 67% 81% 2 654

MDR/RR-TB cases tested for resistance to second-line drugs 54

Laboratory-confirmed cases MDR/RR-TB: 88, XDR-TB: 5

Patients started on treatment **** MDR/RR-TB: , XDR-TB:

Treatment success rate and cohort size Success Cohort

New cases registered in 2016

Previously treated cases registered in 2016 HIV-positive TB cases registered in 2016

MDR/RR-TB cases started on second-line treatment in 2015 XDR-TB cases started on second-line treatment in 2015 TB preventive treatment, 2017

% of HIV-positive people (newly enrolled in care) on preventive treatment

% of children (aged < 5) household contacts of bacteriologically-confirmed TB cases on preventive treatment

TB financing, 2018

National TB budget (US$ millions)

* Ranges represent uncertainty intervals

** MDR is TB resistant to rifampicin and isoniazid; RR is TB resistant to rifampicin

*** Includes cases with unknown previous TB treatment history

**** Includes patients diagnosed before 2017 and patients who were not laboratory-confirmed

***(Rate per 100 000 population per year)

2000 2004 2008 2012 2016 0

0.2 0.4 0.6 0.81

Mortality (excludes HIV+TB)

(Rate per 100 000 population per year)

2000 2004 2008 2012 2016 0

4 8 12

Incidence

Notified (new and relapse)

Incidence (HIV+TB only)

Notified cases by age group and sex, 2017

0-4 05-14 15-24 25-34 35-44 45-54 55-64 65+

400 200 0 200 400 600 800

__Females __Males _ Incidence

Treatment success rate (%)

2000 2002 2004 2006 2008 2010 2012 2014 2016 0

20 40 60 80 100

New cases

Previously treated cases

HIV-positive MDR/RR-TB XDR-TB

Data are as reported to WHO. Estimates of TB and MDR-TB burden are produced by WHO in consultation with countries.

Generated: 2019-03-20 Data: www.who.int/tb/data

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