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Italy Tuberculosis profile

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Italy Tuberculosis profile

Population 2018 61 million

Estimates of TB burdenº, 2018 Number (thousands) Rate

(per 100 000 population)

Total TB incidence 4.3 (3.7–4.9) 7 (6–8.1)

HIV-positive TB incidence 0.2 (0.11–0.32) 0.34 (0.19–0.53)

MDR/RR-TB incidenceºº 0.17 (0.11–0.25) 0.28 (0.18–0.41)

HIV-negative TB mortality 0.34 (0.34–0.34) 0.56 (0.55–0.57) HIV-positive TB mortality 0.031 (0.015–0.054) 0.05 (0.02–0.09) Estimated proportion of TB cases with MDR/RR-TB, 2018

New cases 2.8% (1.8–4.3)

Previously treated cases 13% (7.7–21)

TB case notifications, 2018

Total new and relapse 3 777

- % tested with rapid diagnostics at time of diagnosis 0%

- % with known HIV status

- % pulmonary 71%

- % bacteriologically confirmedººº 80%

- % children aged 0-14 years 4%

- % women 31%

- % men 65%

Total cases notified 3 912

Universal health coverage and social protection

TB treatment coverage (notified/estimated incidence), 2018 88% (77–100) TB patients facing catastrophic total costs

TB case fatality ratio (estimated mortality/estimated incidence), 2018 9% (7–10)

TB/HIV care in new and relapse TB patients, 2018 Number (%)

Patients with known HIV status who are HIV-positive - on antiretroviral therapy

Drug-resistant TB care, 2018

% of bacteriologically confirmed TB cases tested for rifampicin resistance ººº

- New cases 104%

- Previously treated cases 79%

Laboratory-confirmed cases* MDR/RR-TB: 62, XDR-TB: 6

Patients started on treatment* ** MDR/RR-TB: , XDR-TB:

MDR/RR-TB cases tested for resistance to second-line drugs 47

Treatment success rate and cohort size Success Cohort

New cases registered in 2017

Previously treated cases registered in 2017 HIV-positive TB cases registered in 2017

MDR/RR-TB cases started on second-line treatment in 2016 XDR-TB cases started on second-line treatment in 2016 TB preventive treatment, 2018

% of HIV-positive people (newly enrolled in care) on preventive treatment

% of children (aged < 5) household contacts of bacteriologically-confirmed TB cases on preventive treatment

TB financing, 2019

National TB budget (US$ millions)

º Ranges represent uncertainty intervals

ºº MDR is TB resistant to rifampicin and isoniazid; RR is TB resistant to rifampicin ººº Calculated for pulmonary cases only

* Includes cases with unknown previous TB treatment history

** Includes patients diagnosed before 2018 and patients who were not laboratory-confirmed

***(Rate per 100 000 population per year)

2000 2004 2008 2012 2016 0

4 8 12

Total TB incidence

New and relapse TB cases notified

HIV-positive TB incidence

(Rate per 100 000 population per year)

2000 2004 2008 2012 2016 0

0.2 0.4 0.6 0.81

HIV-negative TB mortality

Notified cases by age group and sex, 2018

0-4 05-14 15-24 25-34 35-44 45-54 55-64 65+

400 200 0 200 400 600 800

__Females __Males _ Incidence

Treatment success rate (%)

2000 2002 2004 2006 2008 2010 2012 2014 2016 0

20 40 60 80 100

New cases

Previously treated cases

HIV-positive MDR/RR-TB XDR-TB

Data are as reported to WHO. Estimates of TB and MDR-TB burden are produced by WHO in consultation with countries.

Generated: 2019-10-20 Data: www.who.int/tb/data

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