Dental Research Journal

Dental Research Journal

Original  Article

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Luca  Scapoli¹,  Ambra  Girardi¹,  Annalisa  Palmieri²,  Tiziano  Testori³,  Francesco  Zuffetti³,  Riccardo  Monguzzi⁴,  Dorina  Lauritano⁵,   Francesco  Carinci²

1Departments  of  Histology,  Embryology  and  Applied  Biology,  Centre  of  Molecular  Genetics,  CARISBO  Foundation,  University  of  Bologna,  Bologna,  

2Department   of   Medical-­Surgical   Sciences   of   Communication   and   Behavior,   Section   of   Maxillofacial   and   Plastic   Surgery,   University   of   Ferrara,   Ferrara,  ³Dentistry,  Galeazzi  Hospital,  Milan,  Italy,  ⁴Private  Practice,  Dentist,  Milan,  Italy,  ⁵Neurosciences  and  Biomedical  Technologies,  University   Milano  Bicocca,  Italy

ABSTRACT

%DFNJURXQG Periodontitis is a disease that affects and destroys the tissues that support teeth.

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Porphyromonas gingivalis, Tannerella forsythia DQG Treponema denticola DUH FRQVLGHUHG WKH PDLQ

pathogens involved in periodontitis.

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5HVXOWV6LJQLÀFDQWKLJKHUSUHYDOHQFHRIUHGFRPSOH[VSHFLHVDQGLQFUHDVHGDPRXQWRIP. gingivalis and T. denticola were detected in periodontal pocket of periodontitis patients.

&RQFOXVLRQV Results demonstrated that the test is a valuable tool to improve diagnosis of periodontal disease.

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INTRODUCTION

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Received: August 2012 Accepted: November 2012

Address for correspondence:

Prof. Francesco Carinci, Department of D.M.C.C.C., Section of Maxillofacial and Plastic Surgery, University of Ferrara, Corso Giovecca 203, Ferrara, Italy.

E-mail: crc@unife.it

Access this article online

Website: www.drj.ir

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Table 1: Sample study Sample  study  

features

Totals Health Gingivitis Periodontitis

Subjects (n) 307 66 114 127

Male (n) 124 26 42 56

Female (n) 183 40 72 71

Age (mean years±SD)

39.8r18.9 31.6r18.6 34.3r15.4 48.9r18.2 Sampling

depth (mm±SD) 3.9r1.7 2.6r0.6 3.2r1.0 5.0r1.7

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Table 2: Association analysis between red complex bacteria and periodontitis

Presence/absence  of    bacteria Health  [1] Gingivitis  [2] Periodontitis  [3] OR  (95%  C.I.)

[1]  vs.  [3] [1]+[2]  vs.  [3]

P. gingivalis 5.1 (1.8-4.3) 4.2 (2.6-6.8)

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Positive 22 46 91ss

T. forsythia 6.1 (3.1-11.9) 4.6 (2.6-7.9)

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Positive 29 63 105

T. denticola 3.4 (1.8-6.4) 2.4 (1.5-3.9)

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Positive 24 56 84

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REFERENCES

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Figure 1: Prevalence of red complex bacterial species in healthy (green), gingivitis (yellow), and periodontitis (red) patients

Figure 2: Plots represent the relative amount of each red complex bacterial species in the different group of patients



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