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J.-P. Lepoittevin C. J. Le Coz Dictionary of Contact Allergens

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J.-P. Lepoittevin C. J. Le Coz

Dictionary of Contact Allergens

00_001_006**_Titelei 25.08.2007 10:27 Uhr Seite I

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J.-P. Lepoittevin C. J. Le Coz

With 4 Figures in Color and 12 Tables

With a Contribution by Peter J. Frosch

Dictionary

of Contact Allergens

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Lepoittevin, Jean-Pierre, Professor (e-mail: jplepoit@chimie.u-strasbg.fr) Laboratoire de Dermato-Chimie Clinique Dermatologique, CHU 67091 Strasbourg Cedex, France Le Coz, Christophe J.

(e-mail: christophe.lecoz@wanadoo.fr) Unité Dermato-Allergologie

Hôpitaux Universitaires de Strasbourg 1, Place de l’Hôpital

67091 Strasbourg France

This book is based on Frosch, Menné, Lepoittevin “Contact Dermatitis, 4th Edition”,ISBN 978-3-540-24471-4

Library of Congress Control Number: 2007932601

ISBN 978-3-540-74164-0 Springer Berlin Heidelberg New York

This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilm or in any other way, and storage in data banks. Duplication of this publication or parts thereof is permitted only under the provisions of the German Copyright Law of September 9, 1965, in its current version, and permission for use must always be obtained from Springer. Violations are liable to prosecution under the German Copyright Law.

Springer is a part of Springer Science+Business Media springer.com

© Springer-Verlag Berlin Heidelberg 2007 Printed in Germany

The use of general descriptive names, registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use.

Product liability: the publishers cannot guarantee the accuracy of any information about dosage and application contained in this book. In every individual case the user must check such information by consulting the relevant literature.

Editor: Marion Philipp, Heidelberg, Germany Desk Editor: Ellen Blasig, Heidelberg, Germany Cover: Frido-Steinen-Broo, EStudio, Calamar, Spain Typesetting: K. Detzner, 67346 Speyer, Germany

Production: LE-TeX Jelonek, Schmidt & Vöckler GbR, Leipzig, Germany Printed on acid-free paper 24/3180/YL 5 4 3 2 1 0

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Chemistry plays a major role in our understanding of allergic con- tact dermatitis (ACD), but playing with molecules is not always an easy task for nonspecialists. This book has been written to famil- iarize the reader with the structures of some of the chemicals involved in ACD. We have attempted to provide useful information for those who would like to find out more from the literature or on the internet: the principal name; the most important synonym(s);

the Chemical Abstract Service (CAS) registry number, which is the identity number of a molecule; and a few relevant literature refer- ences. Considering the chemical structure of one molecule and comparing it with that of another is the only way to discuss pos- sible cross-reactions when several patch tests are positive in the same patient.

Most of the molecules listed in this book are not in the European Standard series, nor are they in the more specialized bat- teries, but experience shows that patients can be exposed to them in their environment. Therefore, we have added to this dictionary of contact allergens some guidelines on patch testing with the patients’ own products.

Welcome to the world of chemistry!

Strasbourg, August 2007 Jean-Pierre Lepoittevin Christophe J. Le Coz

Preface

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Contents

Dictionary of Contact Allergens:

Chemical Structures, Sources and References  .  .  .  . 1 Christophe J. Le Coz, Jean-Pierre Lepoittevin

Patch Testing with the Patients’ Own Products  .  .  .  . 255 Peter J. Frosch, Johannes Geier, Wolfgang Uter, An Go ossens

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