TRAN SBR ON CH IAL CR YOBIOPSY IN DIFFUSE P AREN CH YMAL LU NG D IS EA SE Ra venna 27th-28th October 2016Biblioteca Classense

TRAN SBR ON CH IAL CR YOBIOPSY IN DIFFUSE P AREN CH YMAL LU NG D IS EA SE Ra venna 27

-28

October 2016

Via Antonio da Recanate, 2 – 20124 MILANO Tel. +39 02 36590350 – Fax +39 02 67382337 segreteria@aiporicerche.it www.aiporicerche.it ORGANIZING SECRETARIAT VENUEBiblioteca Classense - Sala Muratori Via Baccarini Alfredo 3 - 48100 Ravenna - IT

OFFICIAL LANGUAGEEnglish

CONTINUING MEDICAL EDUCATION (CME) ACCREDITATIONThe Course will be accredited by AIPO - Provider 5079 (Italian Association of Hospital Pulmonologists)to provide Continuing Medical Education (CME) for Italian Physicians.Educational objective 2: guidelines, procedures and clinical documentation ID Code: 168869Participants: 80Italian CME Credits: 14 SCIENTIFIC CHAIRMEN

Stefano GaspariniUniversità Politecnica delle MarcheDipartimento di Scienze Biomediche e Sanità PubblicaS.O.D. di PneumologiaA.O.U. Ospedali Riuniti di Ancona - IT

Venerino PolettiDipartimento Malattie dell’Apparato Respiratorio e del ToraceAzienda USL della RomagnaOspedale G.B Morgagni - L. Pierantoni, Forlì - ITDepartment of Respiratory Diseases and Allergy - Aarhus University Hospital - DK

To certificate CME credits, participants must attend 100% of the Scientific Program.

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PROVIDER NAZIONALE n°5079

SOCIETÀ SCIENTIFICA CERTIFICATA UNI EN ISO 9001:2008PER LA PROGETTAZIONE, GESTIONE ED EROGAZIONE DI EVENTI FORMATIVI E CONGRESSI NELL’AMBITO SANITARIO E NELL’EDUCAZIONE CONTINUA IN MEDICINA (IAF37)

AIPO DICHIARA CHE LE ATTIVITÀ ECM SONO SVOLTE IN MANIERA AUTONOMA ASSUMENDOSI LA RESPONSABILITÀDEI CONTENUTI FORMATIVI, DELLA QUALITÀ SCIENTIFICA E DELLA CORRETTEZZA ETICA DI DETTE ATTIVITÀ

Dal 2004 al servizio della Pneumologia Italianaaiposegreteria@aiporicerche.it www.aiponet.itseguici su Accredited Disciplines: Pulmonology, Oncology, Thoracic Surgery, Pathological Anatomy. Katerina Antoniou, Heraklion, Crete - GRMattia Barbareschi, TrentoMartina Bonifazi, AnconaAlessandra Cancellieri, BolognaAlberto Cavazza, Reggio EmiliaMarco Chilosi, VeronaThomas V. Colby, Rochester, MN - USABruno Crestani, Paris - FRAlessandra Dubini, ForlìBirgitte Folkersen, Aarhus - DK Oren Fruchter, Tel Aviv - ILStefano Gasparini, AnconaSergio Alfonso Harari, MilanoJurgen Hetzel, Tubingen - DPernille Hauschildt, Aarhus - DK FACULTY

Dimitri Leduc, Bruxelles - B

Fabien Maldonado, Nashville, TN - USA

Bruno Murer, Mestre (VE)

Sara Piciucchi, Forlì

Venerino Poletti, Forlì - IT; Aarhus - DK

Claudia Ravaglia, Forlì

Elisabetta Renzoni, London - UK

Jay Ryu, Rochester, MN - USA

Piergiorgio Solli, Forlì

Nicola Sverzellati, Parma

Sara Tomassetti, Forlì

Dominique Valeyre, Paris - FR

Carlo Vancheri, Catania

Simon L. Walsh, London - UK

Athos U. Wells, London - UK Comune di Ravenna

Endorsed by

EUROPEANRESPIRATORYSOCIETY

08.30-09.00

09.00-09.3009.30-10.0010.00-10.3010.30-11.00

11.00-11.20 7th SessionCryo-TBB in DPLD III08.30-09.00Welcome ceremony 27th OCTOBER 2016

Chairpersons:S. A. Harari, V. Poletti 1th SessionClinical corner I

IPF: pathogenesisIPAF, IgG4 and others: the expanding family of ILDsGenetic background of idiopathic interstitial pneumoniasNSIP: an updateCoffee Break 09.00-09.3009.30-10.0010.00-10.3010.30-11.0011.00-11.20 M. Chilosi

J.H. RyuB. CrestaniD. Valeyre

Imaging of idiopathic interstitial pneumonias Uip pattern: radiologic-pathologic correlations 2nd SessionImaging cornerChairpersons:N. Sverzellati, S. Gasparini

S. L. WalshS. Piciucchi 11.20-11.5011.50-12.20 Case DiscussionLunch 3rd SessionMDD corner IChairpersons:E. Renzoni, M. ChilosiC. Ravaglia, S. Piciucchi, A. Dubini12.20.13.0013.00-14.00

The multidisciplinary discussion: what is actually New diagnostic markers 4th SessionClinical corner IIChairpersons:K. Antoniou, V. PolettiA. U. Wells B. Crestani 14.00-14.3014.30-15.00 Chairpersons:C. Vancheri, A. CavazzaCase discussion Remarks on cryobiopsy in diffuse parenchymal lung diseaseLunch 11.20-13.0013.00-13.3013.30-14.309th SessionTribute to Tom Colby careerChairpersons:B. Murer, A. Cavazza

TRAN SBR ON CH IAL CR YOBIOPSY IN DIFFUSE P AREN CH YMAL LU NG D IS EA SE

15.00-15.3015.30-16.00

16.00-16.30 Chairpersons:M. Bonifazi, P. HauschildtTechnical details Standardization and complications of cryo-TBBCoffee Break 5th SessionCryo-TBB in DPLD I

J. HetzelC. Ravaglia

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Multicenter studiesData from the Morgagni hospitalHistopathology of cryo-TBB samplesImmunohistochemistry of cryo-TBBBAL: still a valid diagnostic tool in ILDsCoffee Break Chairpersons:A. Cavazza, P. Solli J. HetzelV. Poletti T. V. ColbyM. ChilosiK. Antoniou 8th SessionMDD corner II

Lung pathology in clinical practice: an introduction Italians at the Mayo clinicLung pathology of diffuse lung disease: an update Why pulmonologists need pathologistsThe Colby milestones in lung pathology: cases I took inspiration from

Conclusions and CME test 14.30-14.5014.50-15.2015.20-15.5015.50-16.2016.20-16.40 16.40-17.20 V. PolettiA. CancellieriM. Barbareschi

A. U. WellsT. V. Colby

M. Chilosi, V. Poletti, J. Ryu The diagnostic work-up of diffuse parenchymal lung disease needs identification of the morphological

aspects in a significant minority of patients. Surgical lung biopsy is considered the most efficient

method to reach the goal so far. However it is associated to a significant incidence of morbidity and

mortality mainly when the definite diagnosis will result to be Idiopathic Pulmonary Fibrosis (IPF) or

in elderly.

Transbronchial lung biopsy with regular forceps is frequently used in clinical practice.

However in this context it is considered less useful because the fragments so obtained are tiny and

with crush artifacts resulting in a very low sensitivity and specificity .

Transbronchial cryobiopsy is an innovative and recently adopted method to obtain larger and well

preserved lung tissue specimens.

In this Course the technical aspects of transbronchial cryobiopsy, its diagnostic role in diffuse

parenchymal lung disease as documented by recent studies or by experience accumulated in

specialized Centers and complications will be presented and discussed.

Stefano Gasparini, Venerino Poletti

Chairpersons:O. Frutcher, C. Ravaglia Cryo-TBB moviesa. Israeli experience b. Belgium experience c. German experience d. Danish experience e. The USA experience 6th SessionCryo-TBB in DPLD II

O. FrutcherD. LeducJ. HetzelB. FolkersenF. Maldonado 17.00-18.15 Lecture

Treatment of IPF: an update16.30-17.00S. Tomassetti Chairperson:V. Poletti S. Tomassetti, S. Piciucchi, A. Dubini

V. Poletti, A. U. Wells