(1)Aplicación del sistema experto SeDeM a la optimización de la fabricación de medicamentos según ICH Q8, Q9 y Q10 Daniel Puñal Peces
Testo completo
(2) UNIVERSITAT DE BARCELONA FACULTAT DE FARMÀCIA DEPARTAMENT DE FARMÁCIA I TECNOLOGIA FARMACÉUTICA. APLICACIÓN DEL SISTEMA EXPERTO SeDeM A LA OPTIMIZACIÓN DE LA FABRICACIÓN DE MEDICAMENTOS SEGÚN ICH Q8, Q9 Y Q10. DANIEL PUÑAL PECES 2014.
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(605) x3 !7]& /. ;
(606) .
(607) • •. • •. • • • •. •. • • • • • •. •. •. •. * |\ x `
(608)
(609) \ *`| }//7 //7 & !&! !K !$ ?5`\6 // *!
(610) @ ` + ` K=x !?& K! { !7
(611) !! =
(612) !W W *
(613) //3 ~7; "; ~ * ]
(614) % xx x ?
(615) ! == !x\ !`%` ///3/7 "~ *& J # W! $ ? K` !! * = x !
(616)
(617) != !K?!
(618) & ! x!% }}/35}67;"; + ! ? W@ J ]+ $!! ]+ ` `?
(619) !+$! } 3/7;~"; +& ?%`=]`% x &{ !7 xx x !?&x {= !+}/3 7" += ! = % `{ <
(620) <! ! / J=
(621) ! `] ` ] <& ! {
(622) K ! ? !x K!?
(623) *+}} 3 7 }" ! ` % % % <xx x !x =&x !
(624) &=
(625) == &x =!&
(626) *+}}3~ 7~}" `+$_-W=7 x!! W! // 3; 5 67 ~K x 56 `+ $ _ - W `= = ` W! // 3;5~67 /" /~ x 5?6 W+ `?& !
(627) ! & ! !
(628) x +}~3 /7/"/
(629) ! % W! == ! x =!=
(630) ?!
(631) &
(632) ? !+`}~ 3;7;;"; x 56
(633) !%# K!=== !x?
(634) ! !+ `}~ 3;7~" x 5?6 W+ <xx x
(635) ! &= = != ? = !! = !!
(636)
(637) !! xx & + }~;3 7; "; ; <`\+@-!x^!!>
(638) ! !<7$
(639) 7 % `
(640) x & /
(641) !&5J`6<!7]?!=& /// ] % *= = !! K
(642) =
(643)
(644) !! x =? ? ! ?& !
(645) ! ! W W *
(646) } 37 " } $ $<` ``\+@-x
(647) ! ! ?& =&
(648) != ! W W *
(649) }}/3;5}67~ "}/ ;
(650) .
(651) •. •. •. •. •. • •. • •. •. •. •. •. ] +@ !!! x = ! \ ! x ? = !! =
(652) & ? x K!=
(653) =
(654) < + @= }}~35 67 }K / ` @ $`= !x=
(655)
(656) == ! x &!& ! ! &! ! !
(657) =
(658)
(659) ! !*+ // 3 7;}"/ ]
(660) !%=!x
(661) !
(662) ?
(663) & x ! =
(664) ! W W *
(665) }} 3 7 /~" ! + ] + _ ! + W =
(666) \ x ! &! K \ !
(667) != ! x x x < + @= // 3. ;5 67 " _ ! ! !! x ! = =
(668) x K!=&K
(669)
(670) =
(671) ! x =&
(672) & ! WW *
(673) // 3 7~ ~"~ } _ - == {= !&! x ! = =
(674) { ! % &}3 567 K _-<{= !!&! !!==
(675) = &<7 +`? + @&
(676) ! <&=
(677) x % & ] W }} 3 7 ;K ~ _? ! - & $< %? == ! x &! ! ]x ! !}~;3~5;67. "; _!x $
(678) x ]< ]\ ` ] =! x =& ! & ! 7 *
(679) !
(680)
(681) +] =!}}~3567}"// _
(682) []][ \K $> \K\+_` % xx x & x == ! x
(683) =!=
(684) &
(685) =
(686) * + }}3 / 7 }" x 56 _
(687) []][ \K $> \K\+_` W =!=
(688) &
(689) x
(690) = !!7 \
(691) x ?&*+}}3/}7 " x 5?6 _
(692) [] ` !
(693)
(694) &
(695) x
(696) =!=
(697) &
(698) < + ` }}3 7 " x 56 _
(699) [ ] \! @ !
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