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BIBLIOGRAFIA

1. R Zucchi, G Chiellini, TS Scanlan and DK Grandy (2006). Review Trace amine-associated receptors and their ligands, Br J Pharm. Br J Pharmacol;149:967–978. 2. Berry, M. D. (2004). Mammalian central nervous system trace amines.

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10. Scanlan T.S., Suchland K.L., Hart M.E., Chiellini G., Huang Y., Kruzich P.J., Frascarelli S., Crossley D.A., Bunzow J.R., Ronca-Testoni S., Lin E.T., Hatton D., Zucchi R., Grandy D.K. (2004) 3-Iodothyronamine is an endogenous and rapid-acting derivative of thyroid hormone. Nat Med;10:638–642.

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56 11. Grandy D.K. (2007) Trace amine-associated receptor 1-Family archetype or

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12. Revel F.G., Moreau J.L., Gainetdinov R.R., Bradaia A., Sotnikova T.D., Mory R., Durkin S. et al. (2011) TAAR1 activation modulates monoaminergic neurotransmission, preventing hyperdopaminergic and hypoglutamatergic activity. Proc Natl Acad Sci U S A;108:8485–8490.

13. Espinoza S., Salahpour A., Masri B., Sotnikova T.D., Messa M., Barak L.S., Caron M.G., Gainetdinov R.R. (2011) Functional interaction between trace amineassociated receptor 1 and dopamine D2 receptor. Mol Pharmacol;80:416–425. 14. Prandi A., Franchini S., Manasieva L.I., Fossa P., Cichero E., Marucci G., Buccioni M., Cilia A., Pirona L., Brasili L. (2012) Synthesis, biological evaluation, and docking studies of tetrahydrofuran- cyclopentanoneand cyclopentanol-based ligands acting at adrenergic α2- and serotonine 5-HT1A receptors. J Med Chem; 55:23–36. 15. Elena Cichero, Stefano Espinoza, Raul R. Gainetdinov, Livio Brasili, Paola Fossa

(2013) Insights into the Structure and Pharmacology of the Human Trace Amine-Associated Receptor 1 (hTAAR1): Homology Modelling and Docking Studies. Chem Biol Drug Des 2013; 81: 509–516.

16. Ghose, K. (1984). Tyramine pressor test: implications and limitations. Methods Find Exp Clin Pharmacol 6, 455–464.

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18. Schäfers, R. F., Poller, U., Pönicke, K., Geissler, M., Daul, A. E., Michel, M. C., et al. (1997). Influence of adrenoceptor and muscarinic receptor blockade on the cardiovascular effects of exogenous noradrenaline and of endogenous noradrenaline released by infused tyramine. Naunyn Schmiedebergs Arch Pharmacol 355, 239– 249.

19. Du, Z. Y., Dusting, G. J., & Woodman, O. L. (1992). Inhibition of nitric oxide synthase specifically enhances adrenergic vasoconstriction in rabbits. Clin Exp Pharmacol Physiol 19, 523–530.

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21. Chiellini G, Frascarelli S, Ghelardoni S, Carnicelli V, Tobias SC, DeBarber A, Brogioni S, Ronca-Testoni S, Cerbai E, Grandy DK, Scanlan TS, Zucchi R. (2007)

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57 Cardiac effects of 3-iodothyronamine: a new aminergic system modulating cardiac function. FASEB J. 2007 Dec;epub.

22. Fehler, M., Kidd, E. J., & Broadley, K. J. (2008). Contraction of rat isolated aorta to trace amines independent of adrenoceptor stimulation.Proc Br Pharmacol Soc 5(issue 2), 024P.

23. Broadley, K.J., Anwar, M.A., Herbert, A.A., Fehler, M., Jones, E.M., Davies, W.E., Kidd, E.J., & Ford, W.R. (2009). Effects of dietary amines on the gut and its vasculature. Br J Nutirtion 101, 1645–1652.

24. Wolinsky TD, Swanson CJ, Smith KE, Zhong H, Borowsky B, Seeman P, Branchek T, Gerald CP. The Trace Amine 1 receptor knockout mouse: an animal model with relevance to schizophrenia. Genes Brain Behav. 2006 Dec 21;epub ahead of print. 25. Liberles SD, Buck LB (2006). A second class of chemosensory receptors in the

olfactory epithelium. Nature 2006;442:645–650. [PubMed: 16878137].

26. Moreno, M., Berry, M. J., Horst, C., Thoma, R., Goglia, F., Harney, J. W., et al. (2005). Activation and inactivation of thyroid hormone by type I iodothyronine deiodinase. Thyroid 15, 787−798.

27. Gloriam, D. E., Bjarnadottir, T. K., Schioth, H. B., & Fredriksson, R. (2005a). High species variation within the repertoire of trace amine receptors. Ann N Y Acad Sci 1040, 323−327.

28. Tan, E. S., Miyakawa, M., Bunzow, J. R., Grandy, D. K., & Scanlan, T. S. (2007). Exploring the structure-activity relationship of the ethylamine portion of 3-iodothyronamine for rat and mouse trace amine-associated receptor 1. J Med Chem 50(12), 2787−2798.

29. Boissier JR, Giudicelli JF, Larno S, Advenier C 1973. Differential inotropic- chronotropic action of thyronamina. Eur J Pharmacol 22:141-149.

30. L.J. Braulke, M. Klingerspor, A. DeBarber, S.C. Tobias, D.K. Grandy, T.S. Scanlan, G. Heldmaier (2008). 3-iodothyronamine: a novel hormone controlling the balance between gluucose and lipid utilization.

31. Giudo Galley, Henri Stalder, Annick Goergler, Marius C. Hoener, Roger D. Norcross (2012). Optimisation of imidazole compound sas selective TAAR1 agonosts: Discovery of RO5073012.

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