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TABLE S1: qRT-PCR analysis of locZ (spr0334) flanking genes in S. pneumoniae.

Comparison of gene transcript levels in WT strains Rx1 (Sp1) and R6 (Sp225) and derived ΔlocZ mutant strains, Sp57 and Sp239, respectively.

a Fold changes represent the ratio of the expression levels of ΔlocZ (Sp57 or Sp239) and WT strain (Sp1 or Sp225).

Fold change of tested genesa

spr0332 spr0333 spr0335 spr0336

Sp57/Sp1 (Rx1) 1.42 (± 0.14) 1.03 (± 0.15) 0.81 (± 0.16) 0.83 (± 0.21) Sp239/Sp225 (R6) 1.02 (± 0.21) 0.86 (± 0.04) 0.69 (± 0.04) 0.76 (± 0.14)

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