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Good and bad microbes: the invisible around us! (Buoni e cattivi: i microbi, gli invisibili intorno a noi)

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(1)

Vivian Tullio

University of Torino

Benessere e Prospettive in medicina

Auditorium Palazzo Italia, 26 luglio 2015

(2)

The Raft of the Lotus Roots

Microbes:

friendly or unfriendly?

(3)

Van Gogh made of Leek

What Are The

Microbes?

They are organisms so

small that a microscope is

needed to study them

(4)

The Anatomy Lesson of Dr. Pickled Cabbage

Who Are The

Microbes?

(5)

Napoleon on Potatos

Bacteria

Singular Bacterium

Bacteria are single-celled microbes with sphaerical, rod, or spiral shapes. They lack the nuclear membrane (Prokaryotic). Some are stationary and others move about.

They range from 0.5 to 2.0 microns in diameter.

(6)

Napoleon on Potatos

Bacteria

Colonies and cells

(7)

Bacteria

Napoleon on Potatos Escherichia coli Salmonella typhi Bacillus/i Coccus/i Streptococcus spp. Staphylococcus spp. Vibrio cholerae Spirillum/a

(8)

Fungi

Yeasts and moulds

Eukariotic with nuclear membrane (Kingdom Fungi are not plant!

Yeasts: single-celled microscopic fungi Moulds: multi-cellular microscopic fungi

Mushrooms:multi-cellular macroscopic fungi About 10 microns in diameter.

The Birth of the Gingerman

Mould Penicillium

(9)

Fungi

Mycosis

The Birth of the Gingerman

Aspergillosis in compromised patients

Ringworm (tinea)

(10)

Viruses

«a piece of bad news wrapped up in proteins»

They are acellular entities too small to be seen with a light microscope! Only two components: a nucleic acid (either DNA or RNA) and a protein capsid.

They replicate themselves only when they have invaded cells (animals, vegetals and bacteria) and cause disease!!!!

Picasso with Onions and Noodles

(11)

Viruses

Picasso with Onions and Noodles

Herpes

(12)

Where Are the

Microbes?

Everywhere: air, soil, water, toys, on

objectives, PC, food, dust, animals, our body!!!

The Kiss of the Radishes

(13)

The Last Supper with the Gingermen

We Are Not

Alone

Microorganisms have a close

association with humans.

They are IN US, ON US, and nearly

everywhere AROUND US

Microbiome

(14)

Pickled Cucumber on the Volga

We are outnumbered.

The average human contains about 10 trillion cells. Microorganisms are about 10 times as many human cells, or 100 trillion microscopic beings…

We Are Not

Alone

(15)

As long as they stay in balance and where they belong, they do us no harm…

We Are Not

Alone

All for one…one for all

The Sleeping Taroman

(16)

The Birth of the Radish

Are microbes

useful?

Many of them provide some important service to us.

Bacteria and fungi are very important in the ecology of our

planet

Microbes are much more our friends than our enemies

(17)

The Dream of the Tofu

Helpful or not?

Recombinant DNA technology: modification of bacterial cells to make substances useful to humans (interferon, insulin, human growth

hormone, new vaccines)

Lactobacillus spp. Bifidobacterium spp.

Probiotics

(18)

Mona Tofu

Helpful or not?

Yeasts and moulds

(19)

Helpful or not?

Most are opportunists, who if given the opportunity of increasing growth or invading

new territory, will cause infection!

Less than 1% of known microbes

cause disease

The Third of May 2008

(20)

How to fight off

harmful

bacteria, fungi

and viruses that

cause

infections?

One of the new strategies is represented by essential oils. They have significant antibacterial,

antifungal, antiviral activity

Liberty Leading the Vegetables

(21)

Ju Duoqi

Cabbage Monroe

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