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Ang II: Angiotensin II

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Glossary

A549: Adenocarcinomic human alveolar basal epithelial cells ACEi: Angiotensin- Converting Enzyme Inhibitor

Ang II: Angiotensin II

ARBs: Angiotensin II- Receptor Blockers AT1: Angiotensin II type 1 receptor AT2: Angiotensin II type 2 receptor C1q: complement component 1 C3: complement component 3 C4: complement component 4

[Ca 2+ ]: intracellular calcium concentration CD4: Cluster of Differentiation 4

COPD: Chronic Obstructive Pulmonary Disease COX-2: Cyclooxygenase-2

CS: Cigarette Smoke

CSE: Cigarette Smoke Extract

DLco: Diffusing capacity of the Lung for Carbon Monoxide EDTA: Ethylenediaminetetraacetic acid

EGTA: Ethylene glycol tetraacetic acid EMP: EndothelialderivedMicroparticles ERK: Extracellular signal-regulated kinase FACS: Fluorescence-Activated Cell Sorting FasL: Fas ligand

FBS: Fetal Bovine Serum

GM-CSF: Granulocyte-Macrophage Colony Stimulating Factor GTPase: Guanidine Triphosphate

HEPES: 4-(2-Hydroxyethyl)piperazine-1-ethanesulfonic acid HIV: Human Immunodeficiency Virus

HUVEC: human vein endothelial cells

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IBMIR: Instant blood-mediated inflammatory reaction ICAM-1: Intercellular Adhesion Molecule 1

IE: islet equivalent IL-1: Interleukin-1 IL-6: Interleukin-6 IL-8: Interleukin-8

iNOS: Inducible Nitric Oxid stynthases Ionophore A23187: Calcium Ionphore JNK1: C-Jun N-terminal kinase -1 LDL: Low-density lipoprotein LMP :Leukocytes derived MP LOS: Losartan

LPS: Lypopolisaccaride

MAPk: Mitogen-activated Protein Kinase MCP-1: Monocytes Chemotactic Protein-1 MI: Miocardial Infarction

MMP-1: Matrix Metalloproteinase-1 MP : Microparticles

NF-kB: Nuclear Factor-kB

NHBEC: Normal Human Bronchial Epithelial Cells NO : Nitric Oxide

OLM: Olmesartan

PAI-1: Plasminogen Activator Inhibitor 1 PBS: Phosphate Buffered Saline

PD 123319: Angiotensin II type 2 receptor antagonist PGI2: Prostaciclin-2

PI: Propidium Iodide

PMP: Platelet-derived Microparticles PS: Phosphatidylserine

PSGL-1: P-selectin glycoprotein ligand-1

RAS: Renin Angiotensin II System

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RFU: Relative Fluorescence Units ROCK I: Rho associated protein kinase1 ROS: Reactive Oxygen Species

SHS: Second Hand Smoke SMCs: Smooth Muscle Cells TF: Tissue Factor

TNF-α: Tumor Necrosis Factor - α TxA 2 : Thromboxane A 2

V-FITC: Annexin V-Fluorescein Isothiocyanate

vWF: Willebrand factor

Riferimenti

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