Ruggero De Paulis, M.D. Curriculum Vitae CURRICULUM VITAE RUGGERO DE PAULIS M.D.

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Curriculum Vitae

CURRICULUM VITAE

RUGGERO DE PAULIS M.D.

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Curriculum Vitae NOME: RUGGERO DE PAULIS, MD

Via del Casaletto 387 00151 Roma

Istituto:

Dipartimento Scienze Cardiovascolari European Hospital

via Portuense 700 00149 Roma

Tel: (06) 65975224 FAX (06) 65975112

e-mail: [email protected] [email protected]

NASCITA 14 Settembre 1958, L'Aquila STATO Coniugato

CIVILE

TITOLO Specializzato in Cardioangiochirurgia (1988) Specializzato in Chirurgia Toracica (1994)

POSIZIONE Dirretore Dipartimento di Cardiochirugia, European Hospital, Roma

MEMBRO DELLE SOCIETA’ SCIENTIFICHE DI:

-American Association Thoracic Surgery (AATS) -European Association Thoracic Surgery (EACTS) -Society of Thoracic Surgeons (STS)

-European Society for Artificial Organs (ESAO)

-International Society for Heart and Lung Trasplantation (ISHLT) -American Society for Artificial Internal Organs (ASAIO)

-Societa' Italiana di Chirurgia Cardiaca e Vascolare (SICCH)

-College Francais de Chirurgie Thoracique and Cardiovasculaire (CFCTCV)

STUDI

1976-1982 Universita' de L' Aquila, L'Aquila

Laurea in Medicina e chirurgia

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Curriculum Vitae 1982 Universita' de L' Aquila, L' Aquila

Abilitazione all' esercizio della professione 1983-1988 Universita' di Torino, Torino

Specializzazione in Cardioangiochirurgia

1984 Idoneita' Dottorato di Ricerca in " Metodologia di ricerca scientifica sperimentale nelle discipline chirurgiche toraco-vascolari. Universita' di Bologna

1986 Institute for Biomedical Engineering, University of Utah, Salt Lake City, Utah.

Postdoctoral Fellowship

1988 Borsa di studio annuale presso Fisiologia Clinica C.N.R. Pisa

1990 Diploma Universitario di Cardiologia Pediatrica e Cardiopatie congenite.

XIII Universita' di Parigi

1990 XII University of Paris; resident in Thoracic and Cardiovascular Surgery 1991 VI University of Paris; Chief resident in Thoracic and Cardiovascular Surgery 1994 Università di Catania, Catania. Specializzazione in Chirurgia Toracica

PREMI e RICONOSCIMENTI

1) Fellowship: S.I.S.M. (Societa' Internazionale Studenti Medicina).

Universita' di Istanbul, Instanbul, Turchia, Agosto 1980

2) Premio annuale " De Gasperi-Donatelli " per la ricerca in Cardiochirurgia.

Milano, Settembre 1985

3) Borsa di Studio presso University of Utah,

Salt Lake City, Utah, U.S.A. Gennaio '86/Marzo'87

4) Premio internazionale Shiley per la ricerca nel campo degli organi artificiali.

Avignone, Francia, Settembre 1986 5) ASAIO Travel Fellowship Award 1987,

New York, Maggio 1987

6) Fase finale Premio " De Gasperi-Donatelli " per la ricerca in Cardiochirurgia.

Milano, Settembre 1987

7) Premio annuale " De Gasperi-Donatelli " per la ricerca in Cardiochirurgia.

Milano, Settembre 1988

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Curriculum Vitae 8) Borsa di Studio annuale presso Fisiologia clinica C.N.R. di Pisa.

9) Premio annuale " De Gasperi-Donatelli " per la ricerca in Cardiochirurgia.

Milano, Settembre 1990

10) Ammissione al "College Francais de Chirurgie Thoracique et Cardiovasculaire"

Paris, France, Giugno 1992

11) Membro Dominio Vascolare della Società European di Chirurgia Toracica e Cardiovascolare (EACTS) (2011-2014)

12) Chairman Dominio Vascolare della Società European di Chirurgia Toracica e Cardiovascolare (EACTS) (2014-2017)

13) Vice Presidente della Società Europea di Chirurgia Toracica e Cardiovascolare (EACTS) (2017-2018)

14) Adjunct Associate Professor of Cardiothoracic Surgery at the Weill Cornell Medical College, New York (2017)

15) Presidente della Società Europea di Chirurgia Toracica e Cardiovascolare (EACTS) (2018- 2019)

16) Membro del Council della Società Europea di Chirurgia Toracica e Cardiovascolare (EACTS) 2014-to date

17) Academician V.I. Bourakovsky Prize for “Outstanding personal contribution to the development of cardiovascular surgery” given by the “Russian Association for Cardiovascular Surgery (Moscow, November 2018)

ESPERIENZA:

1982-1985 Cattedra di Cardiochirurgia, Universita' di Torino, attivita' chirurgica, assistenza clinica pre e postoperatoria inclusa terapia intensiva; maggiore contributo nelle attivita' di ricerca

1986 Postdoctoral fellowship, Artificial Heart Research Laboratory of the Institute for Biomedical Engineering,University of Utah, Salt Lake City, Utah. Responsabile per il training clinico all'impianto del cuore artificiale totale e dei sistemi di assistenza ventricolare (tecniche di impianto, diagnostica postoperatoria ecc.) ai teams americani ed europei autorizzati.

"Principal Investigator" per vitelli e pecore portatori di cuore artificiale totale o

sistemi di assistenza meccanica a scopo di ricerca. L' insieme dell'attivita' didattica

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Curriculum Vitae e di ricerca e' pari ad un totale di 85 impianti di cuore artificiale, 22 impianti di sistemi di assistenza ventricolare ed 19 altre varie procedure chirurgiche. Maggiore contributo alla produzione scientifica.

1987 Ricercatore Universitario presso la cattedra di Cardiochirurgia della Universita' degli Studi di Tor Vergata, Roma.

1987/88 Periodi di missione presso l' Universita' di Torino per ricerca nel campo dei trapianti cardiaci ed assistenza ventricolare

1989 Periodi di ricerca sull' assistenza ventricolare in collaborazione con l' Helmholtz- Institute for Biomedizinische Technik dell' Universita' di Aachen, West Germany 1989/90 Assistente presso il centro di chirurgia toracica e cardiovascolare della

XIII Universita' di Parigi, Hopital "Henri Mondor". Attivita' chirurgica e di ricerca.

1990/91 Aiuto presso il centro di chirurgia toracica e cardiovascolare della VI Universita' di Parigi, Hopital "Lariboisiere". Attivita' chirurgica e di ricerca.

1991/2006 Aiuto strutturato presso la Cattedra di Cardiochirurgia di Roma Tor Vergata.

Attività chirurgica e di ricerca

2002 Professore Associato Confermato Università di Roma Tor Vergata 2006-oggi Direttore Unità Operativa Cardiochirurgia, European Hospital, Roma 2019 Idoneita’ Professore di I fascia in Chirurgia Cardiaca

BREVETTI

1988 Anello per la correzione dell’ insufficienza tricuspidale

1998 Protesi in Dacron per la chirurgia della radice aortica

1999 Posizionatore cardiaco per la chirurgia a cuore battente

2002 Cannula per la perfusione cerebrale anterograda

2004 Cannula per drenaggio versamento pericardico

2010 Anello per la correzione insufficienza mitralica

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Curriculum Vitae DIDATTICA

Scuola di Specializzazione in Cardiochirurgia

1991-2006 Titolare dei corsi di "Bioingegneria", di "Assistenza meccanica cardiocircolatoria"

, di “ Terapia chirurgica e Tecnica Operatoria Malattie del Cuore e Grossi Vasi” e di “Principi e Tecniche della Circolazione Extracorpore

Scuola di Specializzazione in Chirurgia vascolare

1992-2006 Titolare del corso di "Elementi di Bioingegneria"

Scuola di Specializzazione in Medicina Fisica e Riabilitazione

1998-2006 Titolare del corso di "Cardiochirurgia"

2013-present ATTIVITA’ EDUCATIVA PER CONTO DELL’ EACTS (European Association of Cardio-Thoracic Surgery)

Attivita’ chirurgica

Oltre 10000 interventi di Cardiochirurgia

Argomenti principali di ricerca

1) Assisted circulation and total artificial heart 2) Hemodynamic effect of protamine

3) Major sternal wound infection

4) Various aspects of Coronary artery bypass surgery

i) The effect of bilateral internal mammary scheletonization on incidence of sternal wound infection

ii) Ischemic and non-ischemic myocardial preconditioning 5) Surgery of the aortic root

6) The effect of small diameter aortic valve prostheses 7) A new graft for Valve sparing and Bentall operations 8) The role of the sinuses of Valsalva after root reconstruction 9) Aortic surgery and Frozen Elephant Trunk

10) A simplified treatment of the mitral valve in Barlow diseases 11) Long-term results of valve sparing operation

REVISORE RIVISTE SCIENTIFICHE

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Curriculum Vitae

- Heart

- Italian Heart Journal

- The Annals of Thoracic Surgery

- The Journal of Thoracic and Cardiovascular Surgery

- The European Journal of Thoracic and Cardiovascular Surgery - The Journal of Cardiac Surgery

- The European Heart Journal

- Journal of Heart and Valve Disease - Journal of Cardiovascular Medicine - Indian Heart Journal

Associate Editor ICTVS (Interactive Cardiovascular and Thoracic Surgery) (2017-2020)

Revisore esperto per il Ministero Italiano dell’Unversità e della ricerca (MIUR) CINECA-

Valutazione progetti di ricerca (VQR 2004-2010) su commissione dell’ ANVUR (1/2010)

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Curriculum Vitae

Articoli

1) Discepoli S, Iafrate E, De Paulis R: Cholestatic jaundice by intramural mucosal cyst of the intrapancreatic common bile duct.

Ital J Gastroenterol 14: 109-110, 1982

2) Trucano G, di Summa M, Donegani E, De Paulis R: [Post-infarct rupture of the heart and papillary muscle].

Minerva Cardioangiol 33: 831-3, 1985

3) Alloatti G, Montrucchio G, Mariano F, Tetta C, De Paulis R Morea M, Emanuelli G, Camussi G.

Effect of platelet activating factor (PAF) on human cardiac muscle.

Int Archs Allergy appl Immun 79: 108-112, 1986

4) Costa P, Donegani E, De Paulis R, Ottino GM, Villani M, Matani A, Pansini S, Belloni GP, Zaffiri O, Morea M. Diltiazem cold cardioplegia in coronary artery surgery: effects on myocardial ischemia.

Texas Heart Institute Journal 13 (1): 53-60, 1986

5) Donegani E, Costa P, De Paulis R, di Summa M, Poletti GA, Pignatelli GM, Verdecchia C, Morea M:

Myocardial protection by perioperative Diltiazem drip: a clinical evaluation.

Thorac Cardiovasc Surgeon 34: 168-171, 1986

6) Ottino GM, Donegani E, De Paulis R, Sgambettera S: [Pneumopericardium resulting in cardiac tamponade. Description of an atypical case].

Minerva Cardioangiologica 34 (10): 649-652, 1986

7) De Paulis R, Engelhardt H, Riebman JB, Olsen DB. Bloodpumps.

Intern J Artif Organs 9(6):377-384, 1986

8) Pantalos G, Liotta D, Riebman J, Navia J, De Paulis R, Cabrol C, Gandjbakhch I, Pavie A and Kolff WJ. A ventricular assist device in the chest wall: a new approach to an urgent problem.

Life Support System 4 (2): 7-9, 1986

9) Riebman JB, Liotta D, Cabrol C, Cooley DA, Frazier OH, Navia J,Pantalos G, del Rio P, Lima Quintana O, Gandjbakhch I, Pavie A, De Paulis R and Olsen DB. Orthotopic univentricular artificial heart.

Life Support System 4 (2): 47-9, 1986

10) Donegani E, De Paulis R, di Summa M, Poletti GA, Ottino GM, Agaccio G, Casabona R: [Conduction disorders after radical correction of tetralogy of Fallot].

Minerva Cardioangiologica 34 (7-8): 481-486, 1986

11) Donegani E, De Paulis R, Matani A, Agaccio G, Munoz-Castellanos L: [Atrio-ventricular septum defect (canal-type defect). Anatomo-pathologic study in situs solitus and situs inversus].

12) Cesarani F, Gandini G, Avataneo T, De Paulis R, Ottino GM, Marra S, Malara D: [Role of computerized tomography in the control of aortocoronary bypass].

13) Ottino GM, Villani M, De Paulis R, Trucco G, Viara A. Restoration of atrioventricular conduction after surgical removal of a hydatic cyst of the interventricular septum.

J Thorac Cardiovasc Surg 93(1):144-147, 1987

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Curriculum Vitae

14) Ottino GM, De Paulis R, Pansini S, Rocca G, Tallone MV, Comoglio C, Costa P, Orzan F, Morea M.

Major sternal wound infection after open heart surgery: A multivariate analysis of risk factor on 2,579 consecutive operative procedures.

Ann Thorac Surg 44: 173-179, 1987

15) De Paulis R, Carmichael M, Riebman J, Deleuze P and Olsen DB: Cardiectomy for total artificial heart implantation: a modification.

J Heart Transplantation 6: 57-58, 1987

16) De Paulis R, Riebman JB, Deleuze P and Olsen DB. The total artificial heart. Indication and preliminary results.

J Cardiac Surg 2: 2-7 1987

17) De Paulis R, Mohammad FS, Riebman JR, Deleuze P and Olsen DB. Total artificial heart. A better model to study the hemodynamic effect of protamine.

Trans Am Soc Artif Intern Organs 10(3): 217-221, 1987

18) Olsen DB, Riebman JR, De Paulis R, Durrant G and Nielsen S. Registry and Tabulations of orthotopic TAH in man.

19) Verhagen Metman L, De Paulis R, Mohammad SF and Kolff WJ. Evaluation of thrombogenesis on smooth and rough intima in artificial ventricles.

20) Holfert JH, Riebman JB, Dew PA, De Paulis R, Burns GB, Olsen DB. A new connector system for total artificial hearts. Preliminary results.

Trans Am Soc Artif Intern Organ 10(3): 151-156, 1987

21) Donegani E, De Paulis R, Agaccio G, di Summa M, Poletti GA, Pignatelli MG, Matani A. Improved tolerance to ischemia in Hypertrophied myocardium. Pre e post cardiopulmonary by-pass: use of a calcium channel blocker (Diltiazem).

Eur Rev Med & Pharmacol Sci IX: 55-59, 1987

22) Donegani E, De Paulis R, di Summa M, Poletti GA,Morea M, Matani A: Preservation of myocardial ultrastructural integrity following ischemic arrest. Clinical use of nifedipine cardioplegia. Preliminary report.

Eur Rev Med & Pharmacol Sci IX: 363-367, 1987

23) Pantalos G, Marks J, Riebman JB, Burton N, De Paulis R and Kolff WJ. Hemodynamic and energetic assessment of calves implanted with a left ventricular assist device (LVAD).

Intern J Artif Organs 11: 119-126, 1988

24) Ottino GM, Di Leo M, Bergerone, Sacchetti C, De Paulis R, Vuolo, Comoglio C, Brusca A, Morea M.

[Results of coronary artery bypass surgery. Surgical mortality, survival and follow-up functional state.

Multivariate discriminant analysis of relative risk factors].

Giornale Italiano Cardiologia 18: 259-275, 1988

25) Deleuze PH, Riebman JB, De Paulis R, Olsen DB, Loisance DY: Regulation of a pneumatic total artificial heart function: a review.

Intern J Artif Organs 11: 147-152, 1988

26) De Paulis R, Mohammad SF, Chiariello L, Morea M, Olsen DB: A pulmonary mock circulation model for a better understanding of protamine reversal of heparin in blood.

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Curriculum Vitae

Trans Am Soc Artif Int Organs 34: 367-70, 1988

27) Wurzel D, Kolff J, Missfeldt W, Wildevuur W, Hansen G, Brownstein L, Riebman JB, De Paulis R, Kolff WJ: Development of the Philadelphia Heart system.

Artif Organs 12(5) 411-22, 1988

28) Donegani E, De Paulis R, di Summa M, Poletti GA, Matani A, Bobbio M, Morea M. Protection of the heart by Nifedipine cardioplegia during coronary artery surgery. A clinical-hemodynamic evaluation.

Eur J Cardiovasc Surg 2: 442-7, 1988

29) Ottino GM, Bergerone S, Di Leo M, Sacchetti C, De Paulis R, Vuolo A, Golzio PG, Brusca A, Morea M: [Results of aortocoronary bypass surgery: long-term clinical and functional evaluation of patients surviving the operation. Personal experience].

Cardiologia 33: 785-92, 1988

30) Pantalos GM, Marks JD, Riebman JB, Everett SD, Burns GB, De Paulis R: Left ventricular oxigen consumption and organ blood flow distribution during pulsatile ventricular assist.

31) Donegani E, De Paulis R, Matani A, Agaccio G:[Heart transplant. Description of an atypical case of dilated cardiomyopathy].

Minerva Cardioangiol. 36: 511-4, 1988.

32) Giordano G, Formica M, Cavalli G, Amprino MC, Pignatelli MG, De Paulis R, Molino A, Costa P, Roccatello D, Piccoli G: Activation of neutrophil oxydative metabolism during cardiopulmonary bypass with membrane oxygenators.

33) Marks J, Pantalos G, Riebman J Everett S, Burns G, Burton N, De Paulis R: Pressure indices of myocardial oxygen consumption during pulsatile ventricular assistance.

Trans Am Soc Artif Intern Organs 35: 436-9, 1989

34) Donegani E, di Summa M, Agaccio G, Comoglio C, De Paulis R, Matani A: [Pseudomonas aeruginosa infection of the sternum and costal cartilages in cardiosurgery. Therapeutic experience using aztreonam].

Eur Rev Med Pharmacol Sci XI: 143-8, 1989

35) Donegani E, De Paulis R, di Summa M, Agaccio G, Comoglio C, Matani A, Cussino E:[Single cell preparation of the human heart. Technic of dissociation and isolation of myocytes].

Minerva Cardioangiol 38:157-64, 1990

36) Ottino GM, Bergerone S, Di Leo M, Trucano G, Sacchetti C, De Paulis R, Vuolo A, Golzio PG, Brusca A, Morea M. Aortocoronary bypass results. A discriminate multivariate analysis of risk factors of operative mortality.

J Cardiovasc Surg 31 20-25, 1990

37) Roccatello D, Formica M, Cavalli G, Amprino MC, Pignatelli MG, De Paulis R, Costa P, Quattrocchio G, Molino A, Giordano G Changes in neutrophil oxidative potential in patients undergoing cardiopulmonary bypass with polypropilene hollow fiber oxygenators.

Artif Organs 14(1) 69-72, 1990

38) De Paulis R, Riebman JB, Deleuze P, Mohammad SF, Burns GL, Olsen DB. The use of an artificial pericardium with a total artificial heart.

J Cardiovasc Surg 31: 202-8, 1990

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Curriculum Vitae

39) De Paulis R, Engelhardt H, Chiariello L, Reul H, Morea M: In vitro evaluation of a new approach to left ventricular assistance via cannulation of both femoral arteries.

Int J Artif Organs 13: 237-46, 1990

40) De Paulis R, Bobbio M, Ottino GM, Donegani E, Di Rosa E, Casabona R, Girotto M, Morea M: De Vega tricuspid annuloplasty. Perioperative mortality and long term follow-up.

41) Montrucchio G, Alloatti G, Mariano F, De Paulis R, Comino A, Emanuelli G, Camussi G: Role of PAF in an in the reperfusion injury of rabbit ischemic heart.

Am J Pathol 137: 71-83, 1990

42) De Paulis R, Mohammad SF, Chiariello L, Morea M, Olsen DB: The role of plasma proteins in formation of obstructive protamine complexes.

J Cardiothoracic Anesth 5: 227-33, 1991

43) Deleuze Ph, Saada M, De Paulis R, Brochard L, Mazzuccottelli JP, Rotman N, Loisance DY, Cachera JP: Intraoperative transesophageal echocardiography for pulmonary embolectomy without cardiopulmonary bypass.

Ann Thorac Surg 52: 137-8, 1991

44) Fleury JP, De Paulis R, Chevret S, Subayi JB, Oroudji M Menasche Ph, Bloch G, Piwnica A: Is the internal mammary artery an acceptable graft in the elderly patients with left main coronary artery disease? Eur J Cardiothorac Surg 6: 475-8, 1992

45) Casabona R, De Paulis R, Zattera G, Bottone A, di Summa M, Morea M: Stentless porcine and pericardial valve in aortic position.

46) De Paulis R, Fleury JP, Veyssie L, Menasche Ph, Block G, Piwnica A: Acute massive postoperative atrial thrombosis in a patient undergoing low molecular weigh heparin anticoagulation.

J Cardioth Anesth 7: 332-4, 1993

47) De Paulis R, Bassano C, Ricci A, Actis Dato G, Chiariello L: Enzyme levels in shed blood after cardiac operations.

48) Actis Dato G, De Paulis R, De Benedictis M, Actis Dato A, Ricci A, Sommariva L,: Long term follow- up of cardiac mixoma (7-31 years).

49) De Paulis R, Sommariva L, Russo F, Tomai F, Tondo A, Pagliaricci C, Bassano C, Chiariello L:

Doppler echocardiography evaluation of the Carbomedics valve in patients with small aortic anulus and valve prosthesis-body surface area mismatch.

J Thorac Cardiovasc Surg 108: 57-62, 1994

50) Tomai F, Crea F, Gaspardone A, Versaci F, De Paulis R, Esposito C, Chiariello L, Gioffrè PA:

Ischemic preconditioning during coronary angioplasty is prevented by glibenclamide, a selective ATP sensitive K channel blocker.

Circulation 90: 700-5, 1994

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Curriculum Vitae

51) Tomai F, Crea F, Gaspardone A, De Paulis R, Gioffrè PA: Evidence of cardiac suction in the presence of high end-diastolic filling pressure: a case report.

J Heart Valve Dis: 3:300-2, 1994

52) Morea M, De Paulis R, Galloni M, Gastaldi L, di Summa M: Mitral valve replacement with the Biocor stentless mitral valve: early results.

J Heart Valve Dis 3:476-82, 1994

53) De Paulis R, Colella D, Bassano C, Ricci A, Chiariello L: Type A aortic dissection: Management of brain malperfusion through retrograde cerebral perfusion.

54) Tomai F, Crea F, Gaspardone A, Versaci F, De Paulis R, Penta de Peppo A, Bassano C, Chiariello L, Gioffrè PA: Determinants of myocardial ischemia during percutaneous transluminal coronary angioplasty in patients with significant narrowing of a single coronary artery and stable or unstable angina pectoris.

Am J Cardiol 74: 1089-94, 1994

55) Actis Dato G, De Paulis R, Actis Dato A, Bassano C, Pepe N, Borioni R, Panero GB: Correction of pectus excavatum with a self-retaining seagull prosthesis. Long term follow-up.

Chest 107: 303-6, 1995

56) De Paulis R, Engelhardt H, Chiariello L: Is left heart bypass by cannulation of both femoral arteries an effective form of assisted circulation?

57) Penta de Peppo A, Pierri MD, Scafuri A, De Paulis R, Colantuono G, Caprara E, Tomai F, Chiariello L: Intraoperative antifibrinolysis and blood saving techniques in cardiac surgery. Prospective trial of 3 antifibrinolytic drugs.

Tex Heart Inst J 22: 231-6, 1995

58) Gaspardone A, Penta de Peppo A, Pierri M, Cirillo F, Tomai F, De Paulis R, Iamele M, Crea F, Gioffrè PA, Chiariello L. Early postoperative myocardial ischemia after coronary artery bypass grafting. Detrimental effects of nitroglycerine infusion.

Cardiologia 1995; 40 (11): 851-856, 1995.

59) Tomai F, Crea F, Gaspardone A, Versaci F, De Paulis R, Penta de Peppo A, Polisca P, Chiariello L, Gioffrè PA: Effects of A1 Adenosine receptor blockade by bamiphylline on ischemic preconditioning during coronary angioplasty.

Eur Heart J 17: 846-53, 1996

60) De Paulis R, Bognolo G, Tomai F, Bassano C, Tracey M, Chiariello L: Early coronary artery thrombosis in a patient with protein S deficiency.

Eur J Cardio-thorac Surg 10: 470-2, 1996

61) De Paulis R, Sommariva L, De Matteis GM, Polisca P, Tomai F, Penta de Peppo A, Bassano C, Chiariello L: Haemodynamic performances of small diameter CarboMedics and St Jude valves.

J Heart Valve Dis 5(Suppl.III):339-43, 1996

62) De Paulis R, Sommariva L, De Matteis G, Caprara E, Tomai F, Penta de Peppo A, Polisca P, Bassano C, Chiariello L. Extent and pattern of regression of left ventricular hypertrophy in patients with small size CarboMedics aortic valves.

J Thorac Cardiovasc Surg 113: 901-9; 1997.

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Curriculum Vitae

63) Tomai F, Crea F, Gaspardone A, Versaci F, Ghini AS, De Paulis R, Chiariello L, Gioffrè PA:

Phentolamine prevents adaptation to ischemia during coronary angioplasty. Role of a-adrenergic receptors in ischemic preconditioning.

Circulation 96: 2171-7, 1997.

64) De Paulis R, Colagrande L, Seddio F, Picichè M, Penta de Peppo A, Bassano C, Tomai F, Chiariello L:

Levels of troponin I and cardiac enzymes after reinfusion of shed blood in coronary operations.

Ann Thorac Surg 65: 1617-20, 1998.

65) Penta de Peppo A, De Paulis R, Zeitani J, Chiariello L: Autograft from quadrangular resection for floppy valve repair in endocarditis.

Ann Thorac Surg 66: 270-1, 1998.

66) Bassano C, De Paulis R, Penta de Peppo A, Tondo A, Fraticci L, De Matteis GM, Ricci A, Sommariva L, Chiariello L: Residual aortic valve regurgitation after aortic root remodeling without a direct annuloplasty.

Ann Thorac Surg 66: 1269-72, 1998.

67) De Paulis R, Sommariva L, Colagrande L, De Matteis GM, Fratini S, Tomai F, Bassano C, Penta de Peppo A, Chiariello L: Regression of left ventricular hypertrophy after aortic valve replacement for aortic stenosis with different valve substitutes.

J Thorac Cardiovasc Surg 116(4): 590-8, 1998.

68) De Paulis R, Colagrande L, Seddio F, Gaspardone A, Tondo A, Tomai F, Versaci F, Polisca P, Chiariello L: Minor myocardial damage and inflammatory response after three different procedures of left anterior descending artery revascularization.

G Ital Cardiol 29: 375-82, 1999.

69) De Paulis R: The continuing process of modification of a surgical technique.

J Cardiovasc Surg 40: 169-70, 1999.

70) Forlani S, Bassano C, Tomai F, De Paulis R, Penta de Peppo A, Colagrande L, Buratta MM, Chen LW, Matteucci MLS, Chiariello L: Mid-term results of conventional bypass surgery for complex proximal left anterior descending coronary artery stenoses.

G Ital Cardiol 29: 781-86, 1999.

71) De Paulis R, Colagrande L, Seddio F, Chiariello L: Levels of troponin I and cardiac enzymes after reinfusion of shed blood in coronary operations [Letter].

Ann Thorac Surg 68: 630, 1999.

72) De Paulis R, Seddio F, Colagrande L, Polisca P, Chiariello L: Cardiac echinococcosis causing coronary artery disease.

Ann Thorac Surg 67: 1791-3, 1999.

73) Tomai F, De Paulis R, Penta de Peppo A, Colagrande L, Caprara E, Polisca P, de Matteis GM, Ghini A, Forlani S, Colella D, Chiariello L: Beneficial impact of isofluorane during coronary bypass surgery on troponin I release.

G Ital Cardiol 29: 1007-14, 1999.

74) Penta de Peppo A, Polisca P, Tomai F, De Paulis R, Turani F, Zupancich E, Sommariva L, Pasqualetti P, Chiariello L: Recovery of LV contractility in man is enhanced by preischemic administration of enflurane.

75) De Paulis R, Tomai F, Gaspardone A, Colagrande L, Nardi P, Ghini A, Versaci F, de Peppo AP, Gioffre PA, Chiariello L: Coronary flow reserve early and late after minimally invasive coronary artery bypass grafting in patients

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Curriculum Vitae

with totally occluded left anterior descending coronary artery.

J Thorac Cardiovasc Surg. 118: 604-609, 1999.

76) Seddio F, Colagrande L, Pellegrino A, De Paulis R, Bassano C, Chiariello L: Rivascolarizzazione miocardica nella destrocardia con situs inversus.

G Ital Cardiol 29: 1222-6, 1999.

77) De Paulis R, Zeitani J, Bognolo G, Fratini S, Penta de Peppo A, Chiariello L: Left ventricular pseudoaneurysm and mitral valve regurgitation. Conservative surgical therapy.

J Cardiovasc Surg 40(5): 679-81, 1999.

78) Picichè M, De Paulis R, Chiariello L: Unusual origin and fistulization of an aortic pseudoaneurysm: “off pump” surgical repair.

Ann Thorac Surg 68: 1406-7, 1999.

79) Picichè M, De Paulis R, Chiariello L: Review of aortopolmonary fistulas in aortic dissection. Ann Thorac Surg 68: 1833-6, 1999.

80) De Paulis R, Matteucci S, Penta de Peppo A, Chiariello L: Cyanoacrylate glue as an alternative to an additional suture line in the repair of type A aortic dissection.

Tex Heart Inst J 26: 275-7, 1999.

81)

Nardi P, Pellegrino A, De Paulis R, Scafuri A, Versaci F, Polisca P, El-Fakhri F, Chiariello L: Coronary heart surgery in women: risk factors and short-term results.

Ital Heart J 1(4 Suppl): 537-42, 2000.

82) De Paulis R, De Matteis GM, Nardi P, Scaffa R, Colella DF, Chiariello L: A new aortic Dacron conduit for surgical treatment of aortic root pathology.

Ital Heart J 1(7): 457-63, 2000.

83) Tomai F, Crea F, Ghini AS, Proietti I, Gaspardone A, Versaci F, De Paulis R, Chiariello L, Gioffrè PA:

Ischemic preconditioning during coronary angioplasty is preserved in elderly patients.

Ital Heart J 1(8): 562-8, 2000.

84) De Paulis R, Gaspardone A, Coppi G, Colagrande L, Nudi F, Chiariello L: Mechanisms of myocardial ischemia in a patient with left main coronary artery atresia.

Ital Heart J 1(11): 764-6, 2000.

85) De Paulis R, Colagrande L, De Cotiis M, Chiariello L: Heart positioner: an easy access to all coronary artery in beating heart surgery.

Ann Thorac Surg 70:1269-70, 2000.

86) Colagrande L, De Paulis R, Seddio F, Bognolo G, Chiariello L: Anterior diaphragmatic hernia misinterpreted by X-ray, echocardiography, computed tomographic scanning and magnetic resonance imaging.

J Cardiovasc Surg In press, 2000.

87) De Paulis R, De Matteis GM, Chiariello L: Aortic valve sparing procedures.

Heart 85: 5, 2001.

88) De Paulis R, De Matteis GM, Colagrande L, Buratta MM, Chiariello L: Giant left ventricular pseudoaneurysms.

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Curriculum Vitae

89) De Paulis R, De Matteis GM, Nardi P, Scaffa R, Chiariello L: Bentall procedure with a Stentless valve and a new aortic root prosthesis.

Ann Thorac Surg 71: 1375-6, 2001.

90) Bassano C, De Matteis GM, Nardi P, Buratta MM, Zeitani J, De Paulis R, Chiariello L:

Mid-term follow-up of aortic root remodeling compared to Bentall operation.

Eur. J Cardio-thorac Surg 19: 601-5, 2001.

91) Scafuri A, Nardi P, De Paulis R, Buratta MM, Forlani S, Bertoldo F, Chiariello L: Sostituzione aortica isolata con protesi meccanica Carbomedics: nove anni di esperienza clinica e risultati a medio termine.

Ital Heart J Suppl 2(7): 783-7, 2001.

92) De Paulis R, De Matteis GM, Nardi P, Scaffa R, Buratta MM, Chiariello L: Opening and closing characteristics of the aortic valve after valve-sparing procedures using a new aortic root conduit.

Ann Thorac Surg 72: 487-94, 2001.

93) Nardi P, De Paulis R, Penta de Peppo A, Forlani S, Tomai F, Scafuri A, Pellegrino A, Polisca P, Chiariello L: Il bypass aortocoronarico nella disfunzione ventricolare sinistra severa: nove anni di esperienza clinica e risultati a medio termine.

Ital Heart J Suppl 2(8): 894-9, 2001.

94) De Paulis R, De Matteis GM, Nardi P, Scaffa R, Colella DF, Bassano C, Tomai F, Chiariello L: One year appraisal of a new aortic root conduit with sinuses of Valsalva.

J Thorac Cardiovasc Surg 123: 33-9; 2002.

95) De Paulis R, Nardi P, Chiariello L: Valved stentless composite graft. Reply to Urbanski PP Ann Thorac Surg 73:696, 2002.

96) De Paulis R. Invited commentary to : Intermittent aortic cross clamping for CABG by Raco et al.

Ann Thorac Surg 73: 1439-40, 2002.

97) De Paulis R, Penta de Peppo A, Colagrande L, Nardi P, Tomai F, Tomai F, Forlani S, Scafuri A, Picchè M, Chiariello L: Troponin I release after CABG surgery using two different strategies of myocardial protection and systemic perfusion.

J Cardiovasc Surg 43: 153-9; 2002.

98) De Paulis R, Tomai F, Chiariello L: Postoperative transient internal thoracic artery pseudoaneurysm.

99) De Paulis R, De Matteis GM, Nardi P, Scaffa R, Bassano C, Chiariello L: Analysis of valve motion after the reimplantation type of valve sparing procedure (David I) with a new aortic root conduit.

100) Penta de Peppo A, Nardi P, De Paulis R, Pellegrino A, Forlani S, Scafuri A, Chiariello L: Cardiac surgery in moderate to end stage renal failure: analysis of risk factors.

Ann Thorac Surg 74: 378-83, 2002.

101) De Paulis R. Editorial comment: On the fine balance between the completeness of clinical data and the effective use of outcomes data

Eur J Cardiothorac Surg 23: 607-608, 2003.

102) Picichè M, De Paulis R, Fabbri A, Chiariello L: Postoperative aortic fistulas into the airways: etiology, pathogenesis, presentation, diagnosis, and management.

Ann Thorac Surg 75: 1998-2006, 2003.

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Curriculum Vitae

103) De Paulis R: Compliance of aortic root conduit. Reply to Robicsek and Thubrikar.

104) De Paulis R, Bassano C, Scaffa R, Nardi P, Bertoldo F, Chiariello L: Bentall procedures with a novel valved conduit incorporating sinuses of Valsalva

Surgical Technology International XII: 1-6, 2004.

105) De Paulis R, Tomai F, Bertoldo F, Ghini AS, Scaffa R, Nardi P, Chiariello L: Coronary flow characteristics after a Bentall procedure with and without sinuses of Valsalva.

Eur J Cardiothorac Surg Vol 26/1: 66-72, 2004.

106) Zeitani J, Bertoldo F, Nardi P, Iaci G, Polisca P, De Paulis R, Penta de Peppo A, Chiariello L: Influence of patient-prosthesis mismatch on myocardial mass regression and clinical outcome in physically active patients after aortic valve replacement.

J Heart Valve Dis 13(Suppl.I):S63-S67, 2004.

107) De Paulis R, Tomai F, Chiariello L: Reply to: Aazami Eur J Cardiothorac Surg, Volume 26/5: 1056, 2004.

108) De Paulis R, Cetrano E, Moscarelli M, Andò G, Bertoldo F, Scaffa R, Tomai F, Chiariello L Effects of ascending aorta replacement on aortic root dilatation

Eur J Cardiothorac Surg, Volume 27/1: 86-9, 2005.

109) Zeitani J, Penta de Peppo A, De Paulis R, Paolo Nardi, Scafuri A, Versaci F, Chiariello L : Partial Right Internal Thoracic Artery Harvesting is Sufficient for Obtuse Marginal Branch Bypass Grafting.

Ann Thorac Surg. 79(1): p. 361-362, 2005.

110) Tomai F, Andò G, De Paulis R, Chiariello L: Real-time evaluation of the hemodynamic effects of atrial septal defect closure in adults with left ventricular dysfunction.

Catheterization and cardiovascular Intervention 64: 124-6, 2005.

111) De Paulis R, De Notaris S, Scaffa R, Nardella S, Zeitani J, Del Giudice C, Penta de Peppo A, Tomai F, Chiariello L: The effect of bilateral internal thoracic artery harvesting on superficial and deep sternal infection: the role of skeletonization.

J Thorac Cardiovasc Surg.;129:536-43, 2005.

112) Borioni R, Garofalo M, De Paulis R, Nardi P, Scaffa R, Chiariello L. Abdominal Aortic dissections:

anatomic and clinical features and therapeutic options.

Tex Heart Inst J 32:70-3, 2005.

113) Penta de Peppo A, Zeitani J, Nardi P, Iaci G, Polisca P, De Paulis R, Chiariello L. Small "functional" size after mechanical aortic valve replacement: no risk in young to middle-age patients.

Ann Thorac Surg 79:1915-20, 2005.

114) De Paulis R, Schmitz C, Scaffa R, Nardi P, Chiariello L, Reul H. In vitro evaluation of a novel conduit incorporating sinuses of Valsalva.

J Thorac Cardiovasc Surg 130:1016–1021, 2005.

115) Bassano C, Fratticci L, Del Giudice C, Andò G, De Paulis R, Nardi P, El Fakhri F, Chiariello L. Estasia of the ascending aorta at the time of aortic valve surgery: replace or relax?

Ital Heart J 6: 968-71, 2005.

116) Zeitani J, Penta de Peppo A, De Paulis R, Nardi P, Scafuri A, Nardella S, Chiariello L

Benefit of partial right-bilateral internal thoracic artery harvesting in patients at risk of sternal wound complications.

Ann. Thorac. Surg 81:139-43, 2006.

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Curriculum Vitae

117) Forlani S, De Paulis R, Wolf LG, Greco R, Polisca P, Moscarelli M, Chiariello L. Conversion to sinus rhythm by ablation improves quality of life in patients submitted to mitral valve surgery.

Ann Thorac Surg 81:863-7, 2006.

118) Pacini D, Settepani F, De Paulis R, Loforte A, Nardella S, Ornaghi D, Gallotti R, Chiariello L, Di Bartolomeo R. Early results of valve-sparing reimplantation procedure using the Valsalva conduit: a multicenter study.

Ann Thorac Surg 82:865-72, 2006.

119) Settepani F, Szeto WY, Pacini D, De Paulis R, Chiariello L, Di Bartolomeo R, Gallotti R, Bavaria JE.

Reimplantation valve-sparing aortic root replacement in Marfan syndrome using the Valsalva conduit: an intercontinental multicenter study.

Ann Thorac Surg. 83(2):S769-73; discussion S785-902, 2007

120) De Paulis R, Bassano C, Bertoldo F, Chiariello L Aortic valve-sparing operations and aortic root replacement.

J Cardiovasc Med 8(2):97-101, 2007.

121) Morea M, De Paulis R. 'Il buso' (the orifice). How much did Leonardo know of the aortic valve?

J Cardiovasc Med 8(6):399-403, 2007.

122) Maselli D, De Paulis R, Scaffa R, Weltert L, Bellisario A, Salica A, Ricci A. Sinotubular junction size affects aortic root geometry and aortic valve function in the aortic valve reimplantation procedure: an in vitro study using the Valsala graft.

Ann Thorac Surg. 84: 1214-8, 2007.

123) Maselli D, De Paulis R, Weltert L, Salica A, Scaffa R, Bellisario A, Mingiano A. A new method for artificial chordae “tuning” in mitral valve repair: Preliminary experience.

J Thorac Cardiovasc Surg 134:454-9, 2007

124) De Paulis R, Scaffa R, Maselli D, Salica A, Bellisario A, Weltert L. A third generation of ascending aorta Dacron graft. Preliminary experience.

Ann Thorac Surg 85(1):305-9, 2008

125) De Paulis R, Salica A, Maselli D, Scaffa R, Bellisario A, Weltert L. Initial experience of an arterial shunt for bilateral antegrade cerebral perfusion during hypothermic circulatory arrest.

Ann Thorac Surg 85(2):624-7, 2008

126) Borioni R, Garofalo M, De Paulis R, Albano P, Chiariello L. Iatrogenic pseudoaneurysms of the peripheral arteries.

Chir Ital 60:103-11, 2008

127) Borioni R, De Paulis R, Tomai F, Welter L, Fratticci L, Caprara E, Albano P, Garofalo M. Appropriateness

of simultaneous carotid endarterectomy and coronary revascularization.

G Ital Cardiol 9(3):194-8, 2008

128) Weltert L, De Paulis R, Maselli D, Scaffa R.Sorin Solo stentless valve: extended adaptability for sinotubular junction mismatch. Interact Cardiovasc Thorac Surg. 7(4):548-51, 2008

129) Borioni R, Garofalo M, De Paulis R, Albano P, Caprara E, Fratticci L, Chiariello L. Surgical treatment of femoral artery pseudo-aneurysms after cardiac catheterization. Minerva Chir. 63(4):277-82, 2008

130) De Paulis R, Scaffa R, Maselli D, Weltert L, Salica A, Bellisario A. Valsalva graft in the Bentall procedure:

from mechanical valve to the BioValsalva, world's first biological aortic conduit.

Surg Technol Int.17:216-21, 2008

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Curriculum Vitae

131) Rossi P, Bianchi S, Barretta A, Della Scala A, Kornet L, De Paulis R, Bellisario A, D'Addio V, Pavaci H, Miraldi F. Post-operative atrial fibrillation management by selective epicardial vagal fat pad stimulation. J Interv Card Electrophysiol. 24(1):37-45. 2009

132) Weltert L, De Paulis R, Scaffa R, Maselli D, Bellisario A, D'Alessandro S. Re-creation of a sinuslike graft expansion in Bentall procedure reduces stress at the coronary button anastomoses: A finite element study. J Thorac Cardiovasc Surg.137(5):1082-7, 2009

133) De Paulis R, Maselli D, Scaffa R, Nardella S. Double-arterial cannulation for aortic valve replacement with porcelain aorta. Eur J Cardiothorac Surg. 36(4):769-70, 2009

134) Borioni R, De Paulis R, Tomai F, Garofalo M. “On patients undergoing cardiac surgery with asymptomatic unilateral carotid stenoses have a low risk of perioperative stroke. Correspondence.

Eur. J Vasc Surg , 2009

134) De Paulis R, Scaffa R, Nardella S, Maselli D, Weltert L, Bertoldo F, Pacini D, Settepani F, Tarelli G, Gallotti R, Di Bartolomeo R, Chiariello L. Use of the Valsalva graft and long-term follow-up. J Thorac Cardiovasc Surg. 2010;140(6 Suppl):S23-7

135) De Paulis R. Aortic root surgery: from valve sparing to 'spare and plasty Eur J Cardiothorac Surg. 2010;38(5):513-4.

136) Maselli D, Ficarra E, Weltert L, Barberi F, Scaffa R, Bellisario A, De Paulis R. A method to avoid knot- tying in artificial chordae implantation for mitral valve repair. J Heart Valve Dis. 2010;19(2):249-53.

137) Borioni R De Paulis R, Tomai F, Garofalo M. Comment on "patients undergoing cardiac surgery with asymptomatic unilateral carotid stenoses have a low risk of perioperative stroke". Eur J Vasc Endovasc Surg.

2010;39(4):516-7

138) Weltert L, D'Alessandro S, Nardella S, Girola F, Bellisario A, Maselli D, De Paulis R. Preoperative very short-term, high-dose erythropoietin administration diminishes blood transfusion rate in off-pump coronary artery bypass: a randomized blind controlled study. J Thorac Cardiovasc Surg 2010;139(3):621-6

139) ISTHMUS Investigators. The Italian study on the Mitroflow postoperative results(ISTHMUS): a 20-years, multicentre evaluation of mitroglow pericardial bioprosthesis.

Eur J Cardiothorac Surg , 2011;39:18-26

140) De Tullio MD, Pascazio G, Weltert L, De Paulis R, Verzicco R. Evaluation of prosthetic-valved devices by means of numerical simulations

Phil Trans R Soc 2011;369:2502-09

141) Diastolic properties of the Sorin Solo, ATS 3F, Edwards Prima Plus and Medtronic Freestyle stentless valves: an independent in-vitro comparison. Weltert L, Nardella S, Girola F, Scaffa R, Bellisario A, Maselli D, De Paulis R.

J Heart Valve Dis. 2012 Jan;21(1):99-105.

142) Scaffa R, Spaziani C, Leporace M, Leonetti S, Di Roma M, Gaspardone A, De Paulis R (2012). Voluminous Atrial Septal Aneurysm May Mask a Large Double Atrial Septal Defect. ANNALS OF THORACIC SURGERY, vol.

93, p. E41, ISSN: 0003-4975, doi: 10.1016/j.athoracsur.2011.10.029

143) Borioni R, Garofalo M, Nardi P, Weltert L, Scaffa R, De Paulis R, Chiariello L (2012). Twenty years of experience with combined carotid endoarterectomy and coronary artery bypass grafting.. ITALIAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY, vol. 19, p. 97-101, ISSN: 1824-4777

144) Lemma MG, Coscioni E, Tritto FP, Centofanti P, Fondacone C, Salica A, Rossi A, De Santo T, Di Benedetto G, Piazza L, Rinaldi M, Schinosa ALDT, De Paulis R, Contino M, Genoni M (2012). On-pump versus off-pump coronary artery bypass surgery in high-risk patients: Operative results of a prospective randomized trial (on-off

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Curriculum Vitae

study). JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, vol. 143, p. 625-631, ISSN: 0022- 5223, doi: 10.1016/j.jtcvs.2011.11.011

145) Maselli D, Weltert L, Scaffa R, De Paulis R (2012). How to achieve an aortic root remodelling by performing an aortic root reimplantation.. EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, ISSN:

1010-7940

146) Rossi P, Ricci A, De Paulis R, Papi E, Pavaci H, Porcelli D, Monari G, Maselli D, Bellisario A, Turani F, Nardella S, Azzolini P, Piccirillo G, Quaglione R, Valsecchi S, Bianchi S (2012). Epicardial ganglionated plexus stimulation decreases postoperative inflammatory response in humans. HEART RHYTHM, vol. 9, p. 943-950, ISSN:

1547-5271, doi: 10.1016/j.hrthm.2012.01.025

147) Borioni R, Weltert L, De Paulis R, Bellisario A, Maselli D, Tomai F, Garofalo M (2012). Early results of synchronous carotid endarterectomy and off-pump coronary revascularization. JOURNAL OF CARDIOVASCULAR SURGERY, vol. 53, p. 363-367, ISSN: 0021-9509

148) Weltert L, Nardella S, Girola F, Scaffa R, Bellisario A, Maselli D, De Paulis R (2012). Diastolic Properties of the Sorin Solo, ATS 3F, Edwards Prima Plus and Medtronic Freestyle Stentless Valves: An Independent In-Vitro Comparison. JOURNAL OF HEART VALVE DISEASE, vol. 21, p. 99-105, ISSN: 0966-8519

149) Czerny M, Bachet J, Bavaria J, Bonser RS, Borger MA, De Paulis R, Dibartolomeo R, Grabenwöger M, Lonn L, Loubani M, Mestres CA, Schepens MA, Weigang E, Carrel TP (2013). The future of aortic surgery in Europe. EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, ISSN: 1010-7940, doi:

10.1093/EJCTS/EZS413

150) Fu Y, Guidoin R, De Paulis R, Lin J, Li B, Wang L, Nutley M, Desaulniers D, Zhang Z (2013). The Gelweave Valsalva graft to better reconstruct the anatomy of the aortic root. JOURNAL OF LONG-TERM EFFECTS OF MEDICAL IMPLANTS, ISSN: 1050-6934

151) Pisani G, Scaffa R, Ieropoli O, Dell'Amico EM, Maselli D, Morbiducci U, De Paulis R (2013). Role of the sinuses of Valsalva on the opening of the aortic valve. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, vol. 4, p. 999-1003, ISSN: 0022-5223, doi: 10.1016/j.jtcvs.2012.03.060

152) Weltert L, Nardella S, Rondinelli MB, Pierelli L, De Paulis R (2013). Reduction of allogeneic red blood cell usage during cardiac surgery by an integrated intra-and postoperative blood salvage strategy; results of a randomized comparison. TRANSFUSION, vol. 53, ISSN: 0041-1132, doi: 10.1111/J1537-2995.2012.03836.X

153) De Paulis R (2013). Invited commentary.. ANNALS OF THORACIC SURGERY, ISSN: 0003-4975 Guerrieri Wolf L, Scaffa R, Maselli D, Weltert L, Nardella S, Di Roma M, De Paulis R, Tomai F. (2013). Intraaortic migration of an epicardial pacing wire: percutaneous extraction.. ANNALS OF THORACIC SURGERY, ISSN:

0003-4975, doi: 10.1016/j.athoracsur.2012.12.056

154) De Paulis R, Salica A, Pisani G, Morbiducci U, Weltert L, Maselli D (2013). Hemodynamics of the aortic valve and root: implicatrions for surgery. ANNALS OF CARDIOTHORACIC SURGERY, ISSN: 2225-319X, doi:

10.3978/j.issn.2225-319x.2012.11.16

155) Weltert L, de Tullio M, Afferrante L, Salica A, Scaffa R, Maselli D, Verzicco R, De Paulis R (2013).

Annular dilatation and loss of sino-tubular junction in aneurysmatic aorta: implications on leaflet quality at the time of surgery. A finite element study. INTERACTIVE CARDIOVASCULAR AND THORACIC SURGERY, vol. 17, p.

8-12, ISSN: 1569-9293, doi: 10.1093/icvts/ivt116

156) Salica A, Weltert L, Scaffa R, Guerrieri Wolf L, Nardella S, Bellisario A, De Paulis R (2014). Negative pressure wound treatment improves Acute Physiology and Chronic Health Evaluation II score in mediastiniti allowing a successful pectoralis muscle flap closure: six-year experience of a single protocol. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, vol. 148, p. 2397-2403, ISSN: 0022-5223, doi:

10.1016/j.jtcvs.2014.04.025

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Curriculum Vitae

157) Onorati F, D'Errigo P, Barbanti M, Rosato S, Covello RD, Maraschini A, Ranucci M, Santoro G, Tamburino C, Grossi C, Santini F, Menicanti L, Seccareccia F, OBSERVANT Research Group, De Paulis R (2014). Different impact of sex on baseline characteristics and major periprocedural outcomes of transcatheter and surgical aortic valve interventions: Results of the multicenter Italian OBSERVANT Registry.. JOURNAL OF THORACIC AND

CARDIOVASCULAR SURGERY, ISSN: 0022-5223

158) Maselli D, Weltert L, Scaffa R, Nardella S, Guerrieri Wolf L, De Paulis R (2014). Differences in aortic cusp coaptation between the reimplantation and the remodeling techniques of aortic valve-sparir surgery: an in vitro porcine model study. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, p. 615-618, ISSN: 0022- 5223, doi: 10.1016/j.jtcvs.2013.01.029

159) Bashir M, Oo A, De Paulis R, Borger MA, El Khoury G, Bavaria J, Elefteraides JA (2014). Can the Results of Aortic Valve Repair Equal the Results of a Biologic Aortic Valve Replacement?. AORTA, ISSN: 2325-4637 160) De Heer F, Berrebi A, Borger M, Bouche Ot, Cameron D, De Paulis R, Di Cents I, De Kerchove L, El Khoury G, El-Hamamsy I, Klein J, Mecozzi G, Mijiti W, Nijs J, Okita Y, Porras C, Schaefers HJ, Schaff H Shrestha M, Takkenberg J, Vanoverschelde JL, Vojacek J, Lansac E (2014). Aortic Valve Insufficiency and Ascending Aorta Aneurysm International Registry. CARDIOLOGY, ISSN: 0008-6312

161) Salica A, Pisani G, Morbiducci U, Scaffa R, Massai D, Audenino A, Weltert L, Guerrieri Wolf L, De Paulis R (2015). The combined role of sinuses of Valsalva and flow pulsatility improves energy loss of the valve..

EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, ISSN: 1010-7940

162) De Paulis R, Maselli D, Salica A, Leonetti S, Guerrieri Wolf L, Weltert L, Nardella S, Bellisario A (2015).

Mitral repair with the sole use of a semi-rigid band in a sub-population of patients with Barlow's disease: a 4-year follo-ap with stress chocardiography. INTERACTIVE CARDIOVASCULAR AND THORACIC SURGERY, vol.

21, p. 316-321, ISSN: 1569-9293, doi: 10.1093/icvts/ivv170

163) Chimenti C, Scopelliti F, Vulpis E, Tafani M, Villanova L, Verardo R, De Paulis R, Russo MA, Frustaci A.

(2015). Increased oxidative stress contributes to cardiomyocyte dysfuncion and death in patients with Fabry disease cardiomyopathy. HUMAN PATHOLOGY, p. 208-284, ISSN: 0046-8177, doi: 10.1016/j.humpath.2015.07.017 164) De Paulis R, Czerny M, Weltert L, Bavaria J, Borger MA, Carrel TP, Etz CD, Grimm M, Loubani M, Pacini D, Resch T, Urbanski PP, Weigang E, EACTS Vascular Domain Group (2015). Current trends in cannulation and neuroprotection during surgery of the aortic arch in Europe. EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, p. 917-923, ISSN: 1010-7940, doi: 10.1093/ejcts/ezu284

165) Shrestha M, Bachet J, Bavaria J, Carrel TP, De Paulis R, Di Bartolomeo R, Etz CD, Grabenwöger M, Grimm M, Haverich A, Jakob H, Martens A, Mestres CA, Pacini D, Resch T, Schepens M, Urbanski PP, Czerny M (2015).

Current status and recommendations for use of the frozen elephant trunk technique: a position paper by the Vascular Domain of EACTS. EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, vol. 47, p. 759-769, ISSN:

1010-7940, doi: 10.1093/EJCTS/EZV085

166) Weltert L, Rondinelli B, Bello R, Falco M, Bellisario A, Maselli D, Turani F, De Paulis R, Pierelli L (2015).

A single dose of erythropoietin reduces perioparative transfusions in cardiac surgery: results of prospective single- blind randomized controlled trial. TRANSFUSION, p. 1644-1654, ISSN: 0041-1132, doi: 10.1111/trf.13027 167) Tamburino C, Barbanti M, D'Errigo P, Ranucci M, Onorati F, Covello RD, Santini F, Rosato S, Santoro G, Fusco D, Grossi C, Seccareccia F, De Paulis R (2015). 1-Year Outcomes After Transfemoral Transcatheter or Surgical Aortic Valve Replacement: Results From the Italian OBSERVANT Study.. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, ISSN: 0735-1097

168) Moscarelli M, De Paulis R (2016). The golden perfection of the aortic valve. INTERNATIONAL JOURNAL OF CARDIOLOGY, ISSN: 0167-5273

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Curriculum Vitae

168) De Paulis R, D'Aleo S, Bellisario A, Salica A, Weltert L, Scaffa R, Wolf LG, Maselli D, Di Mauro M.

(2016). The fate of small-size pericardial heart valve prostheses in an older patient population.. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, ISSN: 0022-5223, doi: doi: 10.1016/j.jtcvs.2016.08.063 169) Weltert L, D'Aleo S, Chirichilli I, Falco M, Turani F, Bellisario A, De Paulis R (2016). Prospective Randomized Clinical Trial of HEMOPATCH Topical Sealant in Cardiac Surgery. SURGICAL TECHNOLOGY INTERNATIONAL, ISSN: 1090-3941

170) Urbanski PP, Luehr M, Di Bartolomeo R, Diegeler A, De Paulis R, Esposito G, Bonser RS, Etz CD, Kallenbach K, Rylski B, Shrestha ML, Tsagakis K, Zacher M, Zierer A (2016). Multicentre analysis of current strategies and outcomes in open aortic arch surgery: heterogeneity is still an issue.. EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, ISSN: 1010-7940

171) De Paulis R, Chirichilli I, Scaffa R, Weltert L, Maselli D, Salica A, Guerrieri Wolf L, Bellisario A,

Chiariello L. (2016). Long-term results of the valve reimplantation technicque using a graft with sinuses. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, p. 1473-1477, ISSN: 0022-5223, doi:

10.1016/j.jtcvs.2015.08.026

172) Gaudino M, Weltert L, Munjal M, Lau C, Elsayed M, Salica A, Gambardella I, Mills E, De Paulis R, Girardi LN (2016). Early clinical outcome after aortic root replacement using a biological composite valved graft with and without neo-sinuses. EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, ISSN: 1010-7940

173) De Paulis R. Towards a better, complete treatment of aortic arch pathologies.

EUR J CARDIOTHORAC SURG. 2017 Jan;51(suppl 1):i1-i3. doi: 10.1093/ejcts/ezw321.

174) De Paulis R, Weltert L.

Can we quantify the risk of embolization for a free-floating thrombus?

J Thorac Cardiovasc Surg. 2017 Jan 9. pii: S0022-5223(17)30008-9. doi: 10.1016/j.jtcvs.2016.12.025.

175) Gaudino M, Di Franco A, Ohmes LB, Weltert A, Lau C, Gambardella I, Salica A, Munjal M, Elsayed M, Girardi LN, De Paulis R. The Cornell International Consortium for Aortic Surgery (CICAS). Biological solutions to aortic root replacement: valve-sparing versus bioprosthetic conduit. Interact Cardiovasc Thorac Surg in press 176) Chimenti C, Verardo R, Scopelliti F, Grande C, Petrosillo N, Piselli P, De Paulis R, Frustaci A. Myocardial expression of Toll-like receptor 4 predicts the response to immunosuppressive therapy in patients with virus-negative chronic inflammatory cardiomyopathy. Eur J Heart Fail. 2017 Jul;19(7):915-925. doi: 10.1002/ejhf.796. Epub 2017 Mar 31.

177) Gaudino M, Di Franco A, Weltert L, Benedetto U, Lau C, Gambardella I, De Paulis R, Girardi LN; Cornell International Consortium for Aortic Surgery (CICAS). The role of neo-sinus reconstruction in aortic valve-sparing surgery. J Card Surg. 2017 Jun;32(6):328-333. doi: 10.1111/jocs.13143. Epub 2017 May 8.

178) De Paulis R. PRO-CON debate: valve sparing aortic root surgery. PRO: reimplantation. Gen Thorac Cardiovasc Surg. 2017 Oct 10. doi: 10.1007/s11748-017-0837-2. [Epub ahead of print]

179) Luehr M, Peterss S, Zierer A, Pacini D, Etz CD, Shrestha ML, Tsagakis K, Rylski B, Esposito G, Kallenbach K, De Paulis R, Urbanski PP. Aortic events and reoperations after elective arch surgery: incidence, surgical strategies and outcomes. Eur J Cardiothorac Surg. 2018 Mar 1;53(3):519-524. doi: 10.1093/ejcts/ezx378.

180) Galea N, Piatti F, Sturla F, Weinsaft JW, Lau C, Chirichilli I, Carbone I, Votta E, Catalano C, De Paulis R, Girardi LN, Redaelli A, Gaudino M; Cornell International Consortium for Aortic Surgery (CICAS). Novel insights by 4D Flow imaging on aortic flow physiology after valve-sparing root replacement with or without neosinuses. Interact Cardiovasc Thorac Surg. 2018 Jun 1;26(6):957-964. doi: 10.1093/icvts/ivx431.

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Curriculum Vitae

181) De Paulis R. Does being overweight reduce accuracy in predicting an acute aortic dissection? J Thorac Cardiovasc Surg. 2018 May;155(5):1951-1952. doi: 10.1016/j.jtcvs.2017.11.062. Epub 2018 Feb 2. No abstract available.

182) De Paulis R, D'Aleo S, Chirichilli I, Weltert LP. Latest Advances in Cardiac Valvular Replacement. Surg Technol Int. 2018 Jun 1;32:175-189.

183) De Paulis R, Scaffa R, Salica A, Weltert L, Chirichilli I. Biological solutions to aortic root replacement:

valve-sparing versus bioprosthetic conduit. J Vis Surg. 2018 May 9;4:94. doi: 10.21037/jovs.2018.04.12. eCollection 2018. Review.

184) Galea N, Piatti F, Lau C, Sturla F, Weltert L, Carbone I, De Paulis R, Gaudino M, Girardi LN; Cornell International Consortium for Aortic Surgery (CICAS). 4D flow characterization of aortic blood flow after valve sparing root reimplantation procedure. J Vis Surg. 2018 May 9;4:95. doi: 10.21037/jovs.2018.03.17. eCollection 2018.

185) De Paulis R, Weltert LP. You can never step twice in the same river. J Thorac Cardiovasc Surg. 2018 Jul 3.

pii: S0022-5223(18)31758-6. doi: 10.1016/j.jtcvs.2018.06.024. [Epub ahead of print] No abstract available.

186) D'Onofrio A, Tessari C, Filippini C, Bagozzi L, Diena M, Alamanni F, Massetti M, Livi U, Di Eusanio M, Mignosa C, Russo C, Rinaldi M, Di Bartolomeo R, Salvador L, Antona C, Maselli D, De Paulis R, Luzi G, Alfieri O, De Filippo CM, Portoghese M, Musumeci F, Bortolotti U, Gerosa G. Early and Mid-Term Results of Rapid

Deployment Valves: The Intuity Italian Registry (INTU-ITA). Ann Thorac Surg. 2018 Jul 25. pii: S0003- 4975(18)31032-4. doi: 10.1016/j.athoracsur.2018.07.002. [Epub ahead of print]

187) Gaudino M, Piatti F, Lau C, Sturla F, Weinsaft JW, Weltert L, Votta E, Galea N, Chirichilli I, Di Franco A, Francone M, Catalano C, Redaelli A, Girardi LN, De Paulis R. Aortic flow after valve sparing root replacement with or without neosinuses reconstruction. J Thorac Cardiovasc Surg. 2018 Jul 27. pii: S0022-5223(18)32026-9. doi:

10.1016/j.jtcvs.2018.06.094. [Epub ahead of print]

188) Weltert L, Wolf LG, Turani F, De Paulis R. Repair of ruptured coronary sinus by sole apposition of self- adhesive sealing hemostatic patch. J Thorac Cardiovasc Surg. 2018 Jul 29. pii: S0022-5223(18)32036-1. doi:

10.1016/j.jtcvs.2018.07.046. [Epub ahead of print] No abstract available.

189) Weltert L, De Paulis R, Salatino T, Tomai F. Latest Advances in Transcatheter Cardiac Valvular Treatment.

Surg Technol Int. 2018 Sep 10;33. pii: sti33/1036. [Epub ahead of print]

to be updated……….

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Curriculum Vitae

Chapters in book

1) Ottino GM, Comoglio C, De Paulis R, Poletti G, di Summa M, Morea M, Di Leo M, Bergerone S, Gozzellino G, Massobrio M, Orzan F, Brusca A: Terapia chirurgica dell' insufficienza coronarica acuta.

Indicazione e risultati a distanza.

Atti del Simposio Nazionale su "Dieci anni di chirurgia delle coronarie" Orientamenti attuali nel trattamento della cardiopatia ischemica: 149-159, 1983

2) Galloni M, Pansini S, De Paulis R, Zussa C, Talenti E, Morea M: Connective bundle bendings: a significant sign of bioprosthesis worsening.

Biologic and Bioprosthetic Valves. Bodnar E and Yacoub M (Ed).Yorke Medical Books, 391-396, 1985 3) Orzan F, Cervasel C, Friolo S, De Paulis R: Temi di piu' frequente riscontro in operati per difetto di setto interatriale.

Cardiologia '85 (Ed. Librex), pg. 123, 1985

4) Ottino GM, De Paulis R, Trucano G, Malara D, Andreis M, Agaccio G, Donegani E: La TAC nella valutazione dei risultati dell' intervento di Bentall.

"Diagnostica per immagini in patologia vascolare" (Ed Monduzzi): 251-256, 1985

5) Ottino GM, De Paulis R, Malara D, Comoglio C, di Summa M, Donegani E, Morea M: Aneurismi non dissecanti dell' aorta ascendente in fase di rottura.

"Diagnostica per immagini in patologia vascolare" (Ed Monduzzi): 233-241, 1985

6) Donegani E, De Paulis R, Bobbio M, di Summa M, Poletti GA, Agaccio G, Morea M, Ventura T, Calvisi G, Discepoli S. Alterazioni della vena safena prima del suo uso come ponte aortocoronarico. Studio con microscopia ottica.

Angiologia '86 (Ed. Monduzzi, Bologna), pg. 181

7) Morea M, De Paulis R, Olsen DB. Indicazioni cliniche all' impianto del cuore artificiale totale: una revisione dei primi 50 casi.

"Attualita' in Tema di Cardiopatia Ischemica". Atti dei 7 incontri Cardiologici Italo - Monegaschi (Ed G.

Reforzo) pg. 278-287, 1987

8) Olsen DB, De Paulis R. Does the artificial heart work? Experimental and clinical.

"Attualita' in Tema di Cardiopatia Ischemica". Atti dei 7 incontri Cardiologici Italo - Monegaschi (Ed G.

Reforzo) pg. 288-298, 1987

9) De Paulis R, Bobbio M, Donegani E, Ottino GM, Torre C, Agaccio G, Morea M: Trauma endoteliale intraoperatorio della vena safena: analisi con microscopia elettronica a scansione degli effetti della distensione sotto pressione.

Atti del XIII Congresso Nazionale della Societa' di Ricerche in Chirurgia, 597-604, 1987

10) De Paulis R, Galloni M, Ottino GM, Baratta L, Pansini S, Enrici G, di Summa M, Morea M: Risultati delle bioprotesi di Liotta a basso profilo (LPB): follow-up clinico a cinque anni ed analisi delle bioprotesi espiantate.

Atti del XIII Congresso Nazionale della Societa' di Ricerche in Chirurgia, 577-585, 1987

11) Donegani E, De Paulis R, Agaccio G, Morea M, Gastaldi L, Morello M, Casalucci D:

Echocardiographic characteristics of the Pericarbon valve in mitral position.

Cardiovascular Surgery Ed. Montorsi e Granelli IX: 85-88, 1988

12) De Paulis R, Poletti GA, Presbitero P, Donegani E, Morea M.Recovery of ventricular function in an extremely compromised ventricular situation.

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Curriculum Vitae

Proceedings of the First International Workshop on Rotary Blood Pumps. Ed. H. Thoma; pg. 142-52, 1988 13) Morea M, De Paulis R: The future of the artificial heart.

In book: Assisted Circulation 3 Ed F. Unger 612-613, 1989

14) De Paulis R, Olsen DB: Bloodpumps used as a bridge to cardiac transplantation: characteristics and development.

In book: Assisted Circulation 3 Ed F. Unger 313-325, 1989

15) De Paulis R, Fleury JP, Block G, Piwnica A: Heart valve prostheses.

In "Giornate Medico Chirurgiche Internazionali" (Ed Minerva Medica) 887-912, 1991

16) De Paulis R, Girotto M, Morea M: Short report on circulatory assistance: the experience at the University of Torino.

Clinical registry of mechanical circulatory support system applications in Europe. Ed.: J.F. del Canizo.

Proceedings of the expert meeting. Madrid, Maggio 1992

17) De Paulis R, Zattera GF, Parisi F, Leotta E, Casabona R, Galloni M, Pugliese G, di Summa M, Morea M: Indications, implantation techniques, and results of the various types of STL bioprostheses: the surgeon's standpoint. The Sorin stentless pericardial valve. "Symposium on stentless bioprostheses".

In “Stentless Bioprostheses” Eds. Piwnica A, Westaby S. ISIS Medical Media pg.176-81, 1995

18) De Paulis R, Caimmi F, di Summa M, Morea M: The stent in aortic valve prosthesis. In “Heart Surgery 1995” Ed. D’ Alessandro LC, CESI pg. 97-105, 1995

19) Chiariello L, De Paulis R, Vitagliano M, Polisca P: Insufficienza mitralica ischemica cronica. Quando la disfunzione valvolare è da correggere?

In “Chirurgia delle valvulopatie mitraliche” Sostituzione vs riparazione nelle diverse forme eziologiche” Ed.:

Santoli, Fundarò, Salati. 1995: pg. 99-104

20) Chiariello L, De Paulis R, Colagrande L, Seddio F, Zeitani J: Indicazioni alla chirurgia valvolare:

insufficienza mitralica nella cardiopatia ischemica: quando operare.

In Cardiologia 1996, 30° Convegno Internazionale-Attualità in campo cardiologico pg. 104-11, 1996

21) Chiariello L, De Paulis R, Seddio F, Colagrande L, Vitagliano M: La disfunzione papillare post- necrotica: quando diventa un problema chirurgico?

In Cardiologia per immagini 1996; pg. 145-50

22) Chiariello L, De Paulis R, Colagrande L, Seddio F, Zeitani J: L’ insufficienza mitralica nella cardiopatia ischemica: quando operare?

Cardiologia 1996: 434-41, 1996

23) Chiariello L, De Paulis R, Caprara E: Bypass aortocoronarico arterioso: quando e perchè usare le due mammarie e la gastroepiploica destra?

Conoscere e curare il cuore ‘97. Ciba Ed. pag. 309-16, 1997

24) De Paulis R, Donatelli F, Glauber M, Gronda E: Cardiomiopatia e indicazioni estreme alla chirurgia aortica e mitralica. Patologia Valvolare, Strategie a confronto.

2° Seminario Nazionale. St Jude Med. pg. 24-35, 1997

25) De Paulis R: Hemostasys in cardiac surgery. By S. Attar. Recensione.

Ital Heart J 1: 132, 2000

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Curriculum Vitae

26) De Paulis R: The aortic valve after valve-sparing procedures. Vascular Surgery Highlights 2001-02.

Fast Facts. Ed. AH Davies. Health Press. pg. 73.

27) Chiariello L, Nardi P, De Paulis R, Zeitani J, De Notarsi S: Rivascolarizzazione miocardia con le due arterie mammarie interne in pazienti diabetici: vantaggi e svantaggi

In Cardiologia per immagini 2004; Dies Ed.: pg. 133-44.

28) De Paulis R: La chirurgia della radice aortica: un altro passo avanti. In Conoscere e curare il cuore 2007. Atti XXIV Simposio del Centro per la lotta contro l’infarto. Essebiemme Ed.:pg. 89.

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