• Non ci sono risultati.

CAPITOLO 6 BIBLIOGRAFIA

N/A
N/A
Protected

Academic year: 2021

Condividi "CAPITOLO 6 BIBLIOGRAFIA"

Copied!
20
0
0

Testo completo

(1)

43

CAPITOLO 6

BIBLIOGRAFIA

Abdolmaleky HM, Cheng KH, Faraone SV, Wilcox M, Glatt SJ, Gao F, et al. Hypomethylation of MB-COMT promoter is a major risk factor for schizophrenia and bipolar disorder. Hum Mol Genet (2006) 15:3132–4510.1093/hmg/ddl253

Adler C, DelBello M, Strakowski S. Brain network dysfunction in bipolar disorder. CNS Spectrums. 2006;11:312–320.

Altar CA. Neurotrophins and depression Trends. Pharmacology Science 20:59-61, 1999

Angelucci F., Aloe L., Jimenez-Vasquez P., Mathe AA. Lithium treatment alters brain concentrations of nerve growth factor, brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor in a rat model of depression. Int J Neuropsychopharrnacol. 2003;6:225–231 Aprahamian I, Ladeira RB, Diniz BS, Forlenza OV, Nunes PV. Cognitive impairment in euthymic older adults with bipolar disorder: a controlled study using cognitive screening tests. Am J Geriatr Psychiatry. 2014 Apr;22(4):389-97. doi: 10.1016/j.jagp.2012.08.013. Epub 2013 Feb 6.

Asberg M. Neurotransmitters and suicidal behavior. The evidence from cerebrospinal fluid studies. Review. Annals of New York Academy of Science 29;836:158-181, 1997

Aydemir O, Deveci A, Taneli F. The effect of chronic antidepressant treatment on serum brain-derived neurotrophic factor levels in depressed patients: a preliminary study. Progress in Neuropsychopharmacology & Biological Psychiatry 29:261-265, 2005

Baddeley AD, Della Sala S. Working memory and executive control. Philosophical Transactions of the Royal Society of London, 351, 1397-1404. 1996.

Baddeley AD, Hitch G. Working Memory. In Bower Gh (Ed.), The psychology of learning and motivation: advances in research and theory (Vol. 8, pp 47-89). New York: Academic Press.

Bai O., Chlan-Fourney J., Bowen R., Keegan D., Li XM. Expression of brainderived neurotrophic factor mRNA in rat hippocampus after treatment with antipsychotic drugs. J Neurosci Res. 2003;71:127–131.

Barbosa IG, Rocha NP, Huguet RB, Ferreira RA, Salgado JV, Carvalho LA, Pariante CM, Teixeira AL. Executive dysfunction in euthymic bipolar disorder patients and its association with plasma biomarkers. J Affect Disord. 2012 Mar;137(1-3):151-5. doi: 10.1016/j.jad.2011.12.034. Epub 2012 Jan 16.

Barbosa IG, Rocha NP, Miranda AS, Huguet RB, Bauer ME, Reis HJ, Teixeira AL. Increased BDNF levels in long-term bipolar disorder patients. Rev Bras Psiquiatr. 2013 Mar;35(1):67-9. Barker PA. Whither proBDNF. Nat. Neurosci., 12 (2009), pp. 105–106

(2)

44

Barnett JH, Smoller JW. The genetics of bipolar disorder. Neuroscience (2009) 164:331– 4310.1016/j.neuroscience.2009.03.080

Basso MR, Lowery N, Ghormley C, Ward T, Purdie R, Neel J, Combs DR, Bornstein RA. Neuropsychological impairment and psychosis in mania. J Clin Exp Neuropsychol. 2009;31:523– 532. doi: 10.1080/13803390802304516.

Bauer IE, Pascoe MC, Wollenhaupt-Aguiar B, Kapczinski F, Soares JC. Inflammatory mediators of cognitive impairment in bipolar disorder. J Psychiatr Res. 2014 Sep;56:18-27. doi: 10.1016/j.jpsychires.2014.04.017. Epub 2014 May 2.

Becker HE, Nieman DH, Dingemans PM, van de Fliert JR, De Haan L, Linszen DH. Verbal fluency as a possible predictor for psychosis. Eur Psychiatry. 2010;25:105–110.

Begliuomini S, Casarosa E, Pluchino N, Lenzi E, Centofanti M, Freschi L, Pieri M, Genazzani AD, Luisi S, Genazzani AR. Influence of endogenous and exogenous sex hormones on plasma brain-derived neurotrophic factor. Hum Reprod. 2007 Apr;22(4):995-1002. Epub 2007 Jan 24.

Bellivier F, Leroux M, Henry C, Rayah F, Rouillon F, Laplanche JL, et al. Serotonin transporter gene polymorphism influences age at onset in patients with bipolar affective disorder. Neurosci Lett (2002) 334:17–2010.1016/S0304-3940(02)01029-7

Benedetti F, Barbini B, Bernasconi A, Fulgosi MC, Colombo C, Dallaspezia S, et al. Serotonin 5-HT2A receptor gene variants influence antidepressant response to repeated total sleep deprivation in bipolar depression. Prog Neuropsychopharmacol Biol Psychiatry (2008) 32:1863– 610.1016/j.pnpbp.2008.08.017

Benedetti F, Bollettini I, Barberi I, Radaelli D, Poletti S, Locatelli C, et al. Lithium and GSK3-beta promoter gene variants influence white matter microstructure in bipolar disorder. Neuropsychopharmacology (2013) 38:313–2710.1038/npp.2012.172

Benes FM, Matzilevich D, Burke RE, Walsh J. The expression of proapoptosis genes is increased in bipolar disorder, but not in schizophrenia. Mol Psychiatry (2006) 11:241–5110.1038/sj.mp.4001758 Benson BE, Willis MW, Ketter TA, Speer A, Kimbrell TA, Herscovitch P, George MS, Post RM8. Differential abnormalities of functional connectivity of the amygdala and hippocampus in unipolar and bipolar affective disorders. J Affect Disord. 2014 Oct 15;168:243-53. doi: 10.1016/j.jad.2014.05.045. Epub 2014 Jun 2.

Benton AL, Hamsher K. Multilingual Aphasia Examination Manual – revised. Iowa City: University of Iowa; 1978.

Berretta A, Tzeng YC, Clarkson AN. Post-stroke recovery: the role of activity-dependent release of brain-derived neurotrophic factor. Expert Rev Neurother. 2014 Nov;14(11):1335-44.

Bhat S, Dao DT, Terrillion CE, Arad M, Smith RJ, Soldatov NM, et al. CACNA1C (Cav1.2) in the pathophysiology of psychiatric disease. Prog Neurobiol (2012) 99:1– 1410.1016/j.pneurobio.2012.06.001

Bikbova G, Oshitari T, Baba T, Yamamoto S1. Neurotrophic factors for retinal ganglion cell neuropathy - with a special reference to diabetic neuropathy in the retina. Curr Diabetes Rev. 2014 May;10(3):166-76.

(3)

45

Bocchio-Chiavetto L, Zanardini R, Bortolomasi M, Abate M, Segala M, Giacopuzzi M, Riva MA, Marchina E, Pasqualetti P, Perez J, Gennarelli M. Electroconvulsive Therapy (ECT) increases serum Brain Derived Neurotrophic Factor (BDNF) in drug resistant depressed patients. European Neuropsychopharmacology 16(8):620-624, 2006

Bocchio-Chiavetto L, Miniussi C, Zanardini R, Gazzoli A, Bignotti S, Specchia C, Gennarelli M. 5-HTTLPR and BDNF Val66Met polymorphisms and response to rTMS treatment in drug resistant depression. Neuroscience letters 437(2):130-134, 2008

Bonner-Jackson A, Grossman LS, Harrow M, Rosen C. Neurocognition in schizophrenia: a 20-year multi-follow-up of the course of processing speed and stored knowledge. Compr Psychiatry. 2010;51:471–479. doi: 10.1016/j.comppsych.2010.02.005.

Bora E, Yucel M, Pantelis C. Cognitive endophenotypes of bipolar disorder: a meta-analysis of neuropsychological deficits in euthymic patients and their first-degree relatives. J Affect Disord 2009;113(1-2):1-20.

Brietzke E, Stertz L, Fernandes BS, Kauer-Sant’anna M, Mascarenhas M, Escosteguy VargasA, et al. Comparison of cytokine levels in depressed, manic and euthymic patients with bipolar disorder. J Affect Disord (2009) 116:214–710.1016/j.jad.2008.12.001

Bueller JA, Aftab M, Sen S, Gomez-Hassan D, Burmeister M, Zubieta JK. BDNF Val66Met allele is associated with reduced hippocampal volume in healthy subjects. Biol Psychiatry. 2006 May 1;59(9):812-5. Epub 2006 Jan 25.

Buoli M, Caldiroli A, Caletti E, Zugno E, Altamura AC. The impact of mood episodes and duration of illness on cognition in bipolar disorder. Compr Psychiatry. 2014 Oct;55(7):1561-6. doi: 10. 1016/j.comppsych.2014.06.001. Epub 2014 Jun 7.

Carter CJ. eIF2B and oligodendrocyte survival: where nature and nurture meet in bipolar disorder and schizophrenia? Schizophr Bull (2007) 33:1343–5310.1093/schbul/sbm007

Carter CJ. Multiple genes and factors associated with bipolar disorder converge on growth factor and stress activated kinase pathways controlling translation initiation: implications for oligodendrocyte viability. Neurochem Int (2007) 50:461–9010.1016/j.neuint.2006.11.009

Castrén E. Neurotrophins and psychiatric disorders. Handb Exp Pharmacol. 2014;220:461-79. doi: 10.1007/978-3-642-45106-5_17.

Castro LM., Gallant M., Niles LP. Novel targets for valproic acid: up-regulation of melatonin receptors and neurotrophic factors in C6 glioma cells. J Neurochem. 2005;95:1227–1236.

Caylak E. Biochemical and genetic analyses of childhood attention deficit/hyperactivity disorder. Am J Med Genet B Neuropsychiatr Genet. 2012 Sep;159B(6):613-27. doi: 10.1002/ajmg.b.32077. Epub 2012 Jul 23.

Cerullo MA, Adler CM, DelBello MP, Strakowski SM. The functional neuroanatomy of bipolar disorder. International Review of Psychiatry. 2009;21:314–322.

Chen AC, Shin KH, Duman RS, Sanacora G. ECS-induced mossy fiber sprouting and BDNF expression are attenuated by ketamine pretreatment. Journal of ECT 17(1):27- 32, 2001

(4)

46

Chen ZY, Patel PD, Sant G, Meng CX, Teng KK, Hempstead BL, Lee FS. Variant brain-derived neurotrophic factor (BDNF) (Met66) alters the intracellular trafficking and activity-dependent secretion of wildtype BDNF in neurosecretory cells and cortical neurons. Journal of Neuroscience 5;24(18):4401-4411, 2004

Chen PS., Peng GS., Li G., et al. Valproate protects dopaminergic neurons in midbrain neuron/glia cultures by stimulating the release of neurotrophic factors from astrocytes. Mol Psychiatry. 2006;11:1116–1125.

Chepenik LG, Fredericks C, Papademetris X, Spencer L, Lacadie C, Wang F, et al. Effects of the brain-derived neurotrophic growth factor val66met variation on hippocampus morphology in bipolar disorder. Neuropsychopharmacology (2009) 34:944–5110.1038/npp.2008.107

Chlan-Fourney J., Ashe P., Nylen K., Juorio AV., Li XM. Differential regulation of hippocampal BDNF mRNA by typical and atypical antipsychotic administration. Brain Res. 2002;954:11–20. Chou YH, Wang SJ, Lirng JF, Lin CL, Yang KC, Chen CK, Yeh CB, Liao MH. Impaired cognition in bipolar I disorder: the roles of the serotonin transporter and brain-derived neurotrophic factor. J Affect Disord. 2012 Dec 20;143(1-3):131-7. doi: 10.1016/j.jad.2012.05.043. Epub 2012 Aug 11. Civil Arslan F, Tiryaki A, Ozkorumak E. A comparison of euthymic bipolar patients with unaffected first-degree relatives and healthy controls in terms of neuropsychological functions. Int J Psychiatry Clin Pract. 2014 Aug;18(3):208-14. doi: 10.3109/13651501.2013.859706. Epub 2013 Nov 22.

Cohen S, Levi-Montalcini R, HamburgerV. A nerve growth-stimulating factor isolated from sarcom as 37 and 180. Proc Natl Acad Sci U S A, vol. 40, nº 10, pp. 1014-1018. 1954

Craddock N, O'Donovan MC, Owen MJ. The genetics of schizophrenia and bipolar disorder: dissecting psychosis Review. Journal of Medical Genetics 42(3):193-204, 2005

Craddock N, Sklar P. Genetics of bipolar disorder. Lancet (2013) 381:1654–6210.1016/S0140-6736(13)60855-7

Cross-Disorder Group of the Psychiatric Genomics Consortium. Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. Lancet (2013) 381:1371–910.1016/S0140-6736(12)62129-1

Cross-Disorder Group of the Psychiatric Genomics Consortium. Lee SH, Ripke S, Neale BM, Faraone SV, Purcell SM, et al. Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet (2013) 45:984–9410.1038/ng.2711

Crump C, Sundquist K, Winkleby MA & Sundquist J: Comorbidities and mortality in bipolar disorder: a Swedish national cohort study. AMA Psychiatry 2013; 70:931-939.

Cuesta MJ, Peralta V, Zarzuela A. Empirical validation of competing definitions of schizophrenia: a poly-diagnostic study of cognitive impairment in non-affective psychosis. Schizophr Res. 2007;95:39–47. doi: 10.1016/j.schres.2007.06.021.

(5)

47

Cunha AB, Frey B, Andreazza A, Goi JD. Serum brain-derived neurotrophic factor is decreased in bipolar disorder during depressive and manic episodes Neuroscientific Letterature 398:215-219, 2006

Cunha C, Brambilla R, Thomas KL. A simple role for BDNF in learning and memory? Front. Mol. Neurosci., 3 (2010), p. 1

Cvetković-Bosnjak M. [Clinical characteristics of unipolar and bipolar depression] [Article in Croatian]. Med. Pregl.51(7–8),329–332 (1998)

Daban C, Martinez-Aran A, Torrent C, Tabarés-Seisdedos R, Balanzá-Martínez V, Salazar-Fraile J, Selva-Vera G, Vieta E. Specificity of cognitive deficits in bipolar disorder versus schizophrenia. A systematic review. Psychother Psychosom. 2006;75:72–84. doi: 10.1159/000090891.

Daniel BD, Montali A, Gerra ML, Innamorati M, Girardi P, Pompili M, Amore M. Cognitive impairment and its associations with the path of illness in affective disorders: a comparison between patients with bipolar and unipolar depression in remission. J Psychiatr Pract. 2013 Jul;19(4):275-87. doi: 10.1097/01.pra.0000432597.79019.e2.

Dean CE. Antipsychotic-associated neuronal changes in the brain: toxic, therapeutic, or irrelevant to the long-term outcome of schizophrenia? Prog Neuropsychopharrnacol Biol Psychiatry. 2006;30:174–189.

De Sousa RT, Machado-Vieira R, Zarate CA Jr, Manji HK. Targeting mitochondrially mediated plasticity to develop improved therapeutics for bipolar disorder. Expert Opin Ther Targets. 2014 Oct;18(10):1131-47. doi: 10.1517/14728222.2014.940893. Epub 2014 Jul 24.

Dias VV, Brissos S, Frey BN, Andreazza AC, Cardoso C, Kapczinski F. Cognitive function and serum levels of brain-derived neurotrophic factor in patients with bipolar disorder. Bipolar Disord. Sep;11(6):663-71. 2009

Dowlatshahi D, MacQueen GM, Wang JF, Young LT. Increased temporal cortex CREB concentrations and antidepressant treatment in major depression. Lancet 28;352(9142):1754-1755, 1998

Drevets WC, Ongur D, Price JL. Neuroimaging abnormalities in the subgenual prefrontal cortex: implications for the pathophysiology of familial mood disorders. Mol Psychiatry (1998) 3:220– 110.1038/sj.mp.4000370

Drevets WC, Price JL, Furey ML. Brain structural and functional abnormalities in mood disorders: implications for neurocircuitry models of depression. Brain Struct Funct. 2008 Sep; 213(1-2):93-118.

D’Sa C, Duman RS Antidepressants and neuroplasticity. Bipolar Disorders 4:183-194, 2002

Duman RS, Heninger GR, Nestler EJ. A molecular and cellular theory of depression. Archives of General Psychiatry 54:597–605, 1997

Duman RS, Vaidya VA. Molecular and cellular actions of chronic electroconvulsive seizures. The Journal of ECT 14:181–193, 1998

(6)

48

Duman RS. Synaptic plasticity and mood disorder. Molecular Psychiatry 7:29-34, 2002

Duman RS. Role of neurotrophic factors in the etiology and treatment of mood disorders. Neuromolecular Medicine 5:11-25, 2004

Dwivedi Y, Rao JS, Hooriyah SR, Kotowski J, Conley RR, Roberts RC, Tamminga CA, Pandey GN. Abnormal expression and functional characteristics of cyclic adenosine monophosphate response element binding protein in post-mortem brain of suicide subjects. Archives of General Psychiatry 60:273-282, 2003

Egan M, Kojima M, Callicott JH, Goldberg TE, Kolachana BS, Bertolino A, Zaitsev E, Gold B, Goldman D, Dean M, Lu B, Weinberger DR The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function. Cell 112:257-269, 2003

Einat H., Yuan P., Gould TD., et al. The role of the extracellular signal-regulated kinase signaling pathway in mood modulation. J Neurosci. 2003;23:7311–7316.

Fakhry H, El Ghonemy SH, Salem A. Cognitive functions and cognitive styles in young euthymic patients with bipolar I disorder. J Affect Disord. 2013 Oct;151(1):369-77. doi: 10.1016/j.jad.2013.05.095. Epub 2013 Jul 5.

Faraone SV, Tsuang MT. Heterogeneity and the genetics of bipolar disorder. Am J Med Genet C Semin Med Genet (2003) 123C:1–910.1002/ajmg.c.20017

Fernandes BS, Gama CS, Ceresér KM, Yatham LN, Fries GR, Colpo G, de Lucena D, Kunz M, Gomes FA, Kapczinski F. Brain-derived neurotrophic factor as a state-marker of mood episodes in bipolar disorders: a systematic review and meta-regression analysis. J Psychiatr Res. 2011

Aug;45(8):995-1004. doi: 10.1016/j.jpsychires.2011.03.002. Epub 2011 May 6.

Ferreira Ade A, Neves FS, da Rocha FF, Silva GS, Romano-Silva MA, Miranda DM, et al. The role of 5-HTTLPR polymorphism in antidepressant-associated mania in bipolar disorder. J Affect

Disord (2009) 112:267–7210.1016/j.jad.2008.04.012

Finkbeiner S. Calcium regulation of the brain-derived neurotrophic factor gene. Cell Mol Life Sci. 2000 Mar;57(3):394-401.

Francey SM, Jackson HJ, Phillips LJ, Wood SJ, Yung AR, McGorry PD. Sustained attention in young people at high risk of psychosis does not predict transition to psychosis. Schizophr Res. 2005;79:127–136. doi: 10.1016/j.schres.2005.06.023.

Frodl T, Meisenzahl EM, Zetzsche T, Hohne T, Banac S, Schorr C, Jager M, Leinsinger G, Bottlender R, Reiser M, Moller HJ. Hippocampal and amygdala changes in patients with major depressive disorder and healthy controls during a 1-year follow-up. Journal of Clinical Psychiatry 65(4):492-499, 2004

(7)

49

Frodl T, Schule C, Schmitt G, Born C, Baghai T, Zill P, Bottlender R, Rupprecht R, Bondy B, Reiser M, Moller HJ, Meisenzahl EM. Association of the BDNF Val66Met polimorphism with reduced hippocampal volumes in major depression. Archives General Psychiatry 64:410-416, 2007 Fukumoto T., Morinobu S., Okamoto Y., Kagaya A., Yamawaki S. Chronic lithium treatment increases the expression of brain-derived neurotrophic factor in the rat brain. Psychopharmacoiogy (Berl). 2001;158:100–106

Fujimura H, Altar CA, Chen R, Nakamura T, Nakahashi T, Kambayashi J, Sun B, Tandon NN. Brain-derived neurotrophic factor is stored in human platelets and released by agonist stimulation. Thrombosis and Haemostasis 87:728-734, 2002

Geller B, Badner JA, Tillman R, Christian SL, Bolhofner K, Cook EHj. Linkage disequilibrium of the brain-derived neurotrophic factor Val66Met polymorphism in children with a prepubertal and early adolescent bipolar disorder phenotype. American Journal of Psychiatry 161(9):1698-1700, 2004

Genazzani A, Piuchino N, Begliuomini S, Stomati M, Bernardi F, Pieri M, Casarosa E, Palumbo M, Genazzani AD, Luisi M. Long-term low-dose oral administration of dehydroepiandrosterone modulates adrenal response to adrenocorticotropic hormone in early and late postmenopausal women. Gynecological Endocrinology 22(11):627-635, 2006

Gonul AS, Akdenz F, Taneli A, Donat O, Eker C, Vahip S. The effect of treatment on serum brain-derived neurotrophic factor in depressed patients. European Neuropsychopharmacology 13:203, 2003

Gonul A, Akdeniz F, Taneli F, Donat O, Eker C, Vahip S. Effect of treatment on serum brain-derived neurotrophic factor levels in depressed patients. European Archives of Psychiatry & Clinical Neuroscience.255(6):381-386, 2005

González-Blanch C, Rodríguez-Sánchez JM, Pérez-Iglesias R, Pardo-García G, Martínez-García O, Vázquez-Barquero JL, Crespo-Facorro B. First-episode schizophrenia patients neuropsychologically within the normal limits: evidence of deterioration in speed of processing. Schizophr Res. 2010;119:18–26. doi: 10.1016/j.schres.2010.02.1072.

Gottesman II, Gould TD. The endophenotype concept in psychiatry: etymology and strategic intentions. Am J Psychiatry 2003;160(4):636-645.

Green E, Craddock N. Brain-derived neurotrophic factor as a potential risk locus for bipolar disorder: evidence, limitations, and implications. Current Psychiatry Reports 5(6):469-476, 2003 Green EK, Raybould R, Macgregor S, Hyde S, Young AH, O’Donovan MC, et al. Genetic variation of brain-derived neurotrophic factor (BDNF) in bipolar disorder: case-control study of over 3000 individuals from the UK. Br J Psychiatry (2006) 188:21–510.1192/bjp.bp.105.009969

Green MF. Cognitive impairment and functional outcome in schizophrenia and bipolar disorder. J Clin Psychiatry. 2006;67 Suppl 9:3-8; discussion 36-42.

Greenwood KE, Morris R, Sigmundsson T, Landau S, Wykes T. Executive functioning in schizophrenia and the relationship with symptom profile and chronicity. J Int Neuropsychol Soc. 2008;14:782–792.

(8)

50

Hamidi M, Drevets WC, Price JL. Glial reduction in amygdala in major depressive disorder is due to oligodendrocytes. Biol Psychiatry (2004) 55:563–910.1016/j.biopsych.2003.11.006

Harvey PD, Wingo AP, Burdick KE, Baldessarini RJ. Cognition and disability in bipolar disorder: lessons from schizophrenia research. Bipolar Disord. 2010 Jun;12(4):364-75. doi: 10.1111/j.1399-5618.2010.00831.x.

Heinrichs RW, Zakzanis KK. Neurocognitive deficit in schizophrenia: a quantitative review of the evidence. Neuropsychology. 1998;12:426–445.

Hendrick V, Altsuler LL, Gitlin MJ, Delrahim S, Hammen C. Gender and bipolar illness. J. Clin. Psychiatr.61(5),393–396 (2000)

Hobara T, Uchida S, Otsuki K, Matsubara T, Funato H, Matsuo K, et al. Altered gene expression of histone deacetylases in mood disorder patients. J Psychiatr Res (2010) 44:263– 7010.1016/j.jpsychires.2009.08.015

Hong CJ, Huo SJ, Yen FC, Tung CL, Pan GM, Tsai SJ. Association study of a brain- derived neurotrophic-factor genetic polymorphism and mood disorders, age of onset and suicidal behavior. Neuropsychobiology 48(4):186-189, 2003

Hosang GM, Uher R, Keers R, Cohen-Woods S, Craig I, Korszun A, et al. Stressful life events and the brain-derived neurotrophic factor gene in bipolar disorder. J Affect Disord (2010) 125:345– 910.1016/j.jad.2010.01.071

Huang TL, Lee CT, Liu YL. Serum brain-derived neurotrophic factor levels in patients with major depression: effects of antidepressants. J Psychiatr Res. 2008 Jun;42(7):521-5. Epub 2007 Jun 21. Hunsberger J, Austin DR, Henter ID, Chen G. The neurotrophic and neuroprotective effects of psychotropic agents. Dialogues Clin Neurosci. 2009;11(3):333-48.

International Schizophrenia C, Purcell SM, Wray NR, Stone JL, Visscher PM, O’donovan MC, et al. Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature (2009) 460:748–5210.1038/nature08185

Jacobsen JP., Mork A. The effect of escitalopram, desipramine, electroconvulsive seizures and lithium on brain-derived neurotrophic factor mRNA and protein expression in the rat brain and the correlation to 5-HT and 5-HIAA levels. Brain Res. 2004;1024:183–192.

Jakobsen KD, Hansen T, Werge T. Diagnostic stability among chronic patients with functional psychoses: an epidemiological and clinical study. BMC Psychiatry. 2007;7:41. doi: 10.1186/1471-244X-7-41.

Kaija H, Sami A, Martti H, Esa L, Riikka R, Kari M, Terho L. Brainderived neurotrophic factor (BDNF) polymorphisms G196A and C270T are not associated with response to electroconvulsive therapy in major depressive disorder. European Archives of Psychiatry and Clinical Neurosciences. 1(12):24-30, 2006

(9)

51

Kanazawa T, Glatt SJ, Kia-Keating B, Yoneda H, Tsuang MT. Meta-analysis reveals no association of the Val66Met polymorphism of brain-derived neurotrophic factor with either schizophrenia or bipolar disorder. Psychiatric Genetics 17(3):165-170, 2007

Kang H, Welcher AA, Shelton D, Schuman EM . Neurotrophins and time: different roles for TrkB signaling in hippocampal long-term potentiation. Neuron 19(3):653-64, 1997

Karege F, Schwald M, Cisse M. Postnatal developmental profile of brain-derived neurotrophic factor in rat brain and platelets. Neuroscience Letters 328:261-264, 2002

Karege F, Bondolfi G, Gervasoni N, Schwald M, Aubry JM, Bertschy G. Low brain- derived neurotrophic factor (BDNF) levels in serum of depressed patients probably results from lowered platelet BDNF release unrelated to platelet reactivity. Biological Psychiatry 57:1068-1072, 2005 Kauer-Sant'Anna M, Kapczinski F, Andreazza AC, Bond DJ, Lam RW, Young LT, Yatham LN. Brain-derived neurotrophic factor and inflammatory markers in patients with early- vs. late-stage bipolar disorder. Int J Neuropsychopharmacol. 2009 May;12(4):447-58. doi:

10.1017/S1461145708009310. Epub 2008 Sep 4.

Kendler KS, Neale MC. Endophenotype: a conceptual analysis. Mol Psychiatry 2010 February 9. Kenna HA, Reynolds-May M, Stepanenko A, Ketter TA, Hallmayer J, Rasgon NL. Blood levels of brain derived neurotrophic factor in women with bipolar disorder and healthy control women. J Affect Disord. 2014 Mar;156:214-8. doi: 10.1016/j.jad.2013.01.054. Epub 2013 Dec 21.

Kerr N, Dunbar RI, Bentall RP. Theory of mind deficits in bipolar affective disorder. J Affect Disord. 2003;73:253–259.

Kim YK, Jung HG, Myint AM, Kim H, Park SH. Imbalance between pro-inflammatory and anti-inflammatory cytokines in bipolar disorder. J Affect Disord (2007) 104:91– 510.1016/j.jad.2007.02.018

Kim YK, Lee HP, Won SD, Park EY, Lee HY, Lee BH, Lee SW, Yoon D, Han C, Kim DJ, Choi SH. Low plasma BDNF is associated with suicidal behavior in major depression. Progress in Neuropsychopharmacology & Biological Psychiatry 31(1):78- 85, 2007

Konstantakopoulos G, Ioannidi N, Patrikelis P, Soumani A, Oulis P, Sakkas D, Papadimitriou GN, Ploumpidis D. Neurocognitive function in clinically stable patients with schizophrenia or bipolar disorder and normal controls. Psychiatriki. 2011 Jul-Sep;22(3):195-206.

Korte M, Carroll P,Wolf E, Brem G, Thoenen H, Bonhoeffer T. Hippocampal long-term potentiation is impaired in mice lacking brain-derived neurotrophic factor. Proceedings of National Academy of Science USA 12;92(19):8856-8860, 1995

Korte M, Griesbeck O, Gravel C, Carroll P, Staiger V, Thoenen H, Bonhoeffer T. Virus-mediated gene transfer into hippocampal CA1 region restores long-term potentiation in brain-derived neurotrophic factor mutant mice. Proceedings of National Academy ofScience USA 93(22):12547-12552, 1996

(10)

52

Krabbendam L, Arts B, van Os J, Aleman A. Cognitive functioning in patients with schizophrenia and bipolar disorder: a quantitative review. Schizophr Res. 2005;80:137–149. doi: 10.1016/j.schres.2005.08.004.

Kunugi H, Iijima Y, Tatsumi M, Yoshida M, Hashimoto R, Kato T, Sakamoto K., et al. No association between the Val66Met polymorphism of the brain-derived neurotrophic factor gene and bipolar disorder in a Japanese population: a multicenter study. Biological Psychiatry 1;56(5):376-378, 2004

Lang UE, Hellweg R, Seifert F, Schubert F, Gallinat J. Correlation between serum brain-derived neurotrophic factor level and an in vivo marker of cortical integrity. Biological Psychiatry 1;62(5):530-535, 2007

Lang UE, Hellweg R, Gallinat J, Bajbouj M. Acute prefrontal cortex transcranial magnetic stimulation in healthy volunteers: no effects on brain-derived neurotrophic factor (BDNF) concentrations in serum. Journal of Affective Disorders 107(1-3):255- 258, 2008

Latalova K, Prasko J, Diveky T, Velartova H. Cognitive impairment in bipolar disorder. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2011 Mar; 155 (1):19-26

Latalova K, Kamaradova D, Prasko J. Suicide in bipolar disorder: a review. Psychiatr Danub. 2014 Jun;26(2):108-14.

Latremoliere A, Woolf CJ (2009) Central sensitization: a generator of pain hypersensitivity by central neural plasticity. J Pain 10: 895–926. doi: 10.1016/j.jpain.2009.06.012

Lebert F, Lys H, Haëm E, Pasquier F. Dementia following bipolar disorder. Encephale. 2008 Dec;34(6):606-10. doi: 10.1016/j.encep.2007.12.007. Epub 2008 Apr 2.

Le-Niculescu H, Patel SD, Bhat M, Kuczenski R, Faraone SV, Tsuang MT, et al. Convergent functional genomics of genome-wide association data for bipolar disorder: comprehensive identification of candidate genes, pathways and mechanisms. Am J Med Genet B Neuropsychiatr Genet (2009) 150B:155–8110.1002/ajmg.b.30887

Lenox RH, Gould TD, Manji HK. Endophenotypes in bipolar disorder. Am J Med Genet (2002) 114:391–40610.1002/ajmg.10360

Liu DY, Shen XM, Yuan FF, Guo OY, Zhong Y, Chen JG, Zhu LQ, Wu J. The Physiology of BDNF and Its Relationship with ADHD. Mol Neurobiol. 2014 Oct 30.

LeDoux. Emotion circuits in the brain. Annual Review of Neuroscience. 2000;23:155–184

Lee BH, Kim H, Park SH, Kim YK. Decreased plasma BDNF level in depressive patient. Journal of Affective Disorders 10:1016-1022, 2006

Lee YH, Song GG. BDNF 196 G/A and 270 C/T polymorphisms and susceptibility to Parkinson's disease: a meta-analysis. J Mot Behav. 2014;46(1):59-66

(11)

53

Lee SA, Tsao TT, Yang KC, Lin H, Kuo YL, Hsu CH, et al. Construction and analysis of the protein-protein interaction networks for schizophrenia, bipolar disorder, and major depression. BMC Bioinformatics (2011) 12(Suppl 13):S20.10.1186/1471-2105-12-S13-S20

Lessmann V,. Brigadski T.Mechanisms, locations, and kinetics of synaptic BDNF secretion: an update. Neurosci. Res., 65 (2009), pp. 11–22

Leyhe T., Eschweiler GW., Stransky E., et al. Increase of BDNF serum concentration in lithium treated patients with early Alzheimer's disease. J Alzheirners Dis. 2009;16:649–656.

Lipska BK., Khaing ZZ., Weickert CS., Weinberger DR. BDNF mRNA expression in rat hippocampus and prefrontal cortex: effects of neonatal ventral hippocampal damage and antipsychotic drugs. Eur J Neurosci. 2001;14:135–144.

Lommatzsch M, Zingler D, Schuhbaeck K, Schloetcke K, Zingler C, Schuff-Werner P. The impact of age, weight and gender on BDNF levels in human platelets and plasma. Neurobiology of Aging 26:115-123, 2005

Lu J, Wu Y, Sousa N, Almeida OF. SMAD pathway mediation of BDNF and TGF beta 2 regulation of proliferation and differentiation of hippocampal granule neurons. Development. 2005 Jul;132(14):3231-42. Epub 2005 Jun 15.

Lu B, Pang PT, Woo NH. The yin and yang of neurotrophin action. Nat. Rev. Neurosci., 6 (2005), pp. 603–614

Lu B, Nagappan G, Guan X, Nathan PJ, Wren P. BDNF-based synaptic repair as a disease-modifying strategy for neurodegenerative diseases. Nat Rev Neurosci. 2013;14:401–416.

Machado-Vieira R, Dietrich M, Leke R, Cereser V. Decreased plasma brain derived neurotrophic factor levels in unmedicated bipolar patients during manic episode. Biological Psichiatry 61(2):142-144, 2007

Machado-Vieira R, Ibrahim L, Zarate CA., Jr Histone deacetylases and mood disorders: epigenetic programming in gene-environment interactions. CNS Neurosci Ther (2011) 17:699– 70410.1111/j.1755-5949.2010.00203.x

Macqueen G., Yucel K., Taylor V. H., Macdonald K., Joffe R. 2008. Posterior hippocampal volumes are associated with remission rates in patients with major depressive disorder. Biol. Psychiatry 64, 880–883 10.1016/j.biopsych.2008.06.027

Malberg J, Duman RS, Nakagawa S, D'Sa C. Neuronal plasticity and survival in mood disorders. Biological Psychiatry 15;48(8):732-739, 2000

Malhi GS, Ivanovski B, Hadzi-Pavlovic D, Mitchell PB, Vieta E, Sachdev P. Neuropsychological deficits and functional impairment in bipolar depression, hypomania and euthymia. Bipolar Disord. Feb-Mar;9(1-2):114-25. 2007

Malhi GS, Lagopoulos J, Das P, Moss K, Berk M, Coulston CM. A functional MRI study of theory of mind in euthymic bipolar disorder patients. Bipolar Disord. 2008;10:943–956.

(12)

54

Manji HK, Drevets WC, Charney DS. The cellular neurobiology of depression. Nature Medicine 7:541-547, 2001

Mann JJ, McBride PA, Brown RP, Linnoila M, Leon AC, DeMeo M, Mieczkowski T, Myers JE, Stanley M. Relationship between central and peripheral serotonin indexes in depressed and suicidal psychiatric inpatients. Archives of General Psychiatry 49(6):442- 446, 1992

Mann-Wrobel MC, Carreno JT, Dickinson D. Meta-analysis of neuropsychological functioning in euthymic bipolar disorder: an update and investigation of moderator variables. Bipolar Disord 13: 334–342 (2011)

Martinez-Aran A, Vieta E, Reinares M, Colom F, Torrent C, Sánchez-Moreno J, Benabarre A, Goikolea JM, Comes M, Salamero M. Cognitive function across manic or hypomanic, depressed, and euthymic states in bipolar disorder. Am J Psychiatry 2004;161(2):262-270.

Marturana HR, Varela FJ. Autopoiesi e cognizione. Marsilio Saggi. 1992

McDonald A, Shammath-Lagnado S, Shi C, Davis M. Cortical afferents to the extended amygdala. Annals of the New York Academy of Sciences. 1999;877:309–338.

McDonald C, Bullmore ET, Sham PC, Chitnis X, Wickham H, Bramon E, et al. Association of genetic risks for schizophrenia and bipolar disorder with specific and generic brain structural endophenotypes. Arch Gen Psychiatry (2004) 61:974–8410.1001/archpsyc.61.10.974

McEwen BS. Stress and hippocampal plasticity. Annual Reviews of Neuroscience 22:105-122, 1999

McEwen BS. Effects of adverse experiences for brain structure and function. Biological Psychiatry 48(8):721-731, 2000

McMahon FJ, Akula N, Schulze TG, Muglia P, Tozzi F, Detera-Wadleigh SD, et al. Meta-analysis of genome-wide association data identifies a risk locus for major mood disorders on 3p21.1. Nat Genet (2010) 42:128–3110.1038/ng.523

Mega M, Cummings J, Salloway S, Malloy P. The limbic system: An anatomic, phylogenetic, and clinical perspective. Journal of Neuropsychiatry and Clinical Neuroscience. 2000;9:15–330.

Merighi A, Salio C, Ghirri A, Lossi L, Ferrini F, et al. (2008) BDNF as a pain modulator. Prog Neurobiol 85: 297–317. doi: 10.1016/j.pneurobio.2008.04.004

Merikangas KR, Jin R, He JP, Kessler RC, Lee S, Sampson NA, Viana MC, Andrade LH, Hu C, Karam EG, Ladea M, Medina-Mora ME, Ono Y, Posada-Villa J, Sagar R, Wells JE, Zarkov Z. Prevalence and correlates of bipolar spectrum disorder in the world mental health survey initiative. Arch Gen Psychiatry. 2011 Mar;68(3):241-51. doi: 10.1001/archgenpsychiatry.2011.12.

Miguel L, Roncero C, López-Ortiz C, Casas M. [Epidemiological and diagnostic axis I gender differences in dual diagnosis patients]. Adicciones23(2),165–172 (2011).

(13)

55

Miller LJ, Ghadiali NY, LaRusso EM, Wahlen KJ, Avni-Barron O, Mittal L, Greene JA. Bipolar Disorder in Women. Health Care Women Int. 2014 Oct 14:0. [Epub ahead of print]

Mitoma M, Yoshimura R, Sugita A, Umene W, Hori H, Nakano H, Ueda N, Nakamura J. Stress at work alters serum brain-derived neurotrophic factor (BDNF) levels and plasma 3-methoxy-4-hydroxyphenylglycol (MHPG) levels in healthy volunteers: BDNF and MHPG as possible biological markers of mental stress? Progress in Neuropsychopharmacology & Biological Psychiatry 1;32(3):679-685, 2008

Monteleone P, Serritella C, Martiadis V, Maj M. Decreased levels of serum brain- derived neurotrophic factor in both depressed and euthymic patients with unipolar depression and in euthymic patients with bipolar I and II disorders. Bipolar Disorders 10(1):95-100, 2008

Munkholm K, Vinberg M, Berk M, Kessing LV. State-related alterations of gene expression in bipolar disorder: a systematic review. Bipolar Disord (2012) 14:684–9610.1111/bdi.12005

Munkholm K, Brauner JV, Kessing LV, Vinberg M. Cytokines in bipolar disorder vs. healthy control subjects: a systematic review and meta-analysis. J Psychiatr Res (2013) 47:1119– 3310.1016/j.jpsychires.2013.05.018

Munkholm K, Vinberg M, Vedel KL. Cytokines in bipolar disorder: A systematic review and meta-analysis. J Affect Disord (2013) 144:16–2710.1016/j.jad.2012.06.010

Murer MG, Boissiere F, Yan Q, Hunot S, Villares J, Faucheux B, Agid Y, Hirsch E, Raisman-Vozari R. An immunohistochemical study of the distribution of brain-derived neurotrophic factor in the adult human brain, with particular reference to Alzheimer׳s disease. Neuroscience, 88 (1999), pp. 1015–1032

Nagatsu T. Molecular mechanisms of neurotransmission. Rinsho Shinkeigaku 40(12):1185-1188, 2000

Nakata K, Ujike H, Sakai A, Uchida N, Nomura A, Imamura T, Katsu T, Tanaka Y, Hamamura T, Kuroda S. Association study of the brainderived neurotrophic factor (BDNF) gene with bipolar disorder. Neuroscientific Letterature 30;337(1):17-20, 2003

Nestler EJ, Barrot M, DiLeone Rj, Eisch AJ, Gold Sj, Monteggia LM. Neurobiology of depression. Neuron 34(1):13-25, 2002

Nestler EJ, Carlezon WA Jr. The mesolimbic dopamine reward circuit in depression. Review. Biological Psychiatry 15;59(12):1151-1159, 2006

Neves-Pereira M, Mundo E, Muglia P, King N, Macciardi F, Kennedy JL. The brain- derived neurotrophic factor gene confers susceptibility to bipolar disorder: Evidence from a family-based association study. American Journal of Human Genetics 71:651- 655, 2002

Neves FS, Silveira G, Romano-Silva MA, Malloy-Diniz L, Ferreira AA, De Marco L, et al. Is the 5-HTTLPR polymorphism associated with bipolar disorder or with suicidal behavior of bipolar disorder patients? Am J Med Genet B Neuropsychiatr Genet (2008) 147B:114– 610.1002/ajmg.b.30563

(14)

56

Nibuya M, Morinobu S, Duman RS. Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments. The Journal of Neuroscience 15:7539-7547, 1995

Nivoli AM, Pacchiarotti I, Rosa AR et al. Gender differences in a cohort study of 604 bipolar patients: the role of predominant polarity. J. Affect. Disord.133(3),443–449 (2011).

Nobuyuki Takei, Kazuo Furukawa, Osamu Hanyu, Hirohito Sone, and Hiroyuki Nawa. A possible link between BDNF and mTOR in control of food intake. Front Psychol. 2014; 5: 1093.

Nurnberger JI, Jr, Koller DL, Jung J, Edenberg HJ, Foroud T, Guella I, et al. Identification of pathways for bipolar disorder: a meta-analysis. JAMA Psychiatry (2014) 71:657– 6410.1001/jamapsychiatry.2014.176

Offord J. Genetic approaches to a better understanding of bipolar disorder. Pharmacol Ther (2012) 133:133–4110.1016/j.pharmthera.2011.10.001

Okasha TA, El Sheikh MM, El Missiry AA, El Missiry MA, El Serafi D, El Kholy S, Abdel Aziz K. Cognitive functions in euthymic Egyptian patients with bipolar disorder: are they different from healthy controls? J Affect Disord. 2014 Sep;166:14-21. doi: 10.1016/j.jad.2014.04.051. Epub 2014 May 5.

Olié E, Seyller M, Beziat S, Loftus J, Bellivier F, Bougerol T, Belzeaux R, Azorin JM, Gard S, Kahn JP, Passerieux C, Leboyer M, Etain B, Henry C, Courtet P. Clinical and neuropsychological characteristics of euthymic bipolar patients having a history of severe suicide attempt. Acta Psychiatr Scand. 2014 Aug 6. doi: 10.1111/acps.12326.

Ongur D, Drevets WC, Price JL. Glial reduction in the subgenual prefrontal cortex in mood disorders. Proceedings of National Academy of Science USA 95:13290-13295, 1998

Organization WH. The World Health Report 2002: Reducing Risks, Promoting Healthy Life. Geneva: World Health Organization; 2002. Oct 30, 2002.

Osuji IJ, Cullum CM. Cognition in bipolar disorder. Psychiatr Clin North Am. 2005 Jun;28(2):427-41.

Pace TW, Hu F, Miller AH. Cytokine-effects on glucocorticoid receptor function: relevance to glucocorticoid resistance and the pathophysiology and treatment of major depression. Brain Behav Immun (2007) 21:9–1910.1016/j.bbi.2006.08.009

Padmos RC, Hillegers MH, Knijff EM, Vonk R, Bouvy A, Staal FJ, et al. A discriminating messenger RNA signature for bipolar disorder formed by an aberrant expression of inflammatory genes in monocytes. Arch Gen Psychiatry (2008) 65:395–40710.1001/archpsyc.65.4.395

Palomino A, Vallejo-Illarramendi A, Gonzalez-Pinto A, Aldama A, Gonzalez-Gomez C, Mosquera F, Gonzalez-Garcia G, Matute C. Decreased levels of plasma BDNF in first-episode schizophrenia and bipolar disorder patients. Schizophrenic Research 86(1- 3):321-322, 2006

Pan W, Banks WA, Fasold MB, Bluth J, Kastin AJ. Transport of brain-derived neurotrophic factor across the blood-brain barrier. Neuropharmacology 37(12):1553- 1561, 1998

(15)

57

Pardridge WM. Blood-brain barrier drug targeting enables neuroprotection in brain ischemia following delayed intravenous administration of neurotrophins. Advances in Experimental Medicine and Biology 513:397-430, 2002

Parikh V., Khan MM., Mahadik SP. Olanzapine counteracts reduction of brain-derived neurotrophic factor and TrkB receptors in rat hippocampus produced by haloperidol. Neurosci Lett. 2004;356:135–139.

Patapoutian A, Reichardt LF. Trk receptors: mediators of neurotrophin action. Current Opinions in Neurobiology 11(3):272-280, 2001

Patterson SL, Grover LM, Schwartzkroin PA, Bothwell M. Neurotrophin expression in rat hippocampal slices: a stimulus paradigm inducin LTP in CA1 evokes increases in BDNF and NT-3 mRNAs. Neuron 9:1081-1088, 1992

Patterson SL, Abel T, Deuel TA, Martin KC, Rose JC, Kandel ER. Recombinant BDNF rescues deficits in basal synaptic transmission and hippocampal LTP in BDNF knockout mice. Neuron 6:1137-1145, 1996

Pelleymounter MA, Cullen MJ, Wellman CL. Characteristics of BDNF-induced weight loss. Exp Neurol. 1995 Feb; 131(2):229-38.

Piccinni A, Del Debbio A, Schiavi E, Palla A, Mariotti A, Bianchi C, Roncaglia I, Catena M, Dell’Osso L. Studio preliminare sull’esistenza di un ritmo circadiano del BDNF. Comunicazione Congresso SOPSI, 2006

Piccinni A, Marazziti D, Catena M, Domenici L, Del Debbio A, Bianchi C, Mannari C, Martini C, Da Pozzo E, Schiavi E, Mariotti A, Roncaglia I, Palla A, Consoli G, Giovannini L, Massimetti G, Dell'Osso L. Plasma and serum brain-derived neurotrophic factor (BDNF) in depressed patients during 1 year of antidepressant treatments. Journal of Affective Disorders 105(1-3):279-283, 2008 Pierce RC, Bari AA. The role of neurotrophic factors in psychostimulant-induced behavioral and neuronal plasticity. Reviews in Neuroscience. 12(2):95-110, 2001

Pillai A., Terry AV., Jr., Mahadik SP. Differential effects of long-term treatment with typical and atypical antipsychotics on NGF and BDNF levels in rat striatum and hippocampus. Schizophr Res. 2006;82:95–106.

Piccinni A, Veltri A, Costanzo D, Vanelli F, Franceschini C, Moroni I, Domenici L, Origlia N, Marazziti D, Akiskal HS, Dell'Osso L. Decreased plasma levels of brain-derived neurotrophic factor (BDNF) during mixed episodes of bipolar disorder. J Affect Disord. 2014 Sep 28;171C:167-170. doi: 10.1016/j.jad.2014.08.058. [Epub ahead of print]

Poduslo JF, Curran GL. Permeability at the blood-brain and bloodnerve barriers of the neurotrophic factors: NGF, CNTF, NT-3, BDNF. Molecular Brain Research 36(2):280- 286, 1996

Poo MM. Neurotrophins as synaptic modulators. Nature Reviews Neuroscience 2:24- 32, 2001 Pruunsild P, Kazantseva A, Aid T, Palm K, Timmusk T. Dissecting the human BDNF locus: bidirectional transcription, complex splicing, and multiple promoters. Genomics, 90 (2007), pp. 397–406

(16)

58

Purcell SM, Moran JL, Fromer M, Ruderfer D, Solovieff N, Roussos P, et al. A polygenic burden of rare disruptive mutations in schizophrenia. Nature (2014) 506:185–9010.1038/nature12975

Radka SF, Holst PA, Fritsche M, Altar CA. Presence of brain-derived neurotrophic factor in brain and human and rat but not mouse serum detected by a sensitive and specific immunoassay. Brain Research 709(1):122-301, 1996

Rajkowska G, Miguel-Hidalgo JJ, Wei J, Dilley G, Pittman SD, Meltzer HY, Overholser JC, Roth BL, Stockmeier CA. Morphometric evidence for neuronal and glial prefrontal cell pathology in major depression. Biological Psychiatry 1;45(9):1085-1098, 1999

Rajkowska G. Postmortem studies in mood disorders indicate altered numbers of neurons and glial cells. Biological Psychiatry 15;48(8):766-777, 2000

Rajkowska G, Halaris A, Selemon LD. Reductions in neuronal and glial density characterize the dorsolateral prefrontal cortex in bipolar disorder. Biol Psychiatry (2001) 49:741–5210.1016/S0006-3223(01)01080-0

Reichenberg A, Harvey PD, Bowie CR, Mojtabai R, Rabinowitz J, Heaton RK, Bromet E. Neuropsychological function and dysfunction in schizophrenia and psychotic affective disorders. Schizophr Bull. 2009;35:1022–1029. doi: 10.1093/schbul/sbn044.

Reitan RM. Validity of the Trail Making Test as an indicator of organic brain damage. Percept Mot Skills 1958;8:271-276.

Robinson LJ, Thompson JM, Gallagher P, Goswami U, Young AH, Ferrier IN, et al. A meta-analysis of cognitive deficits in euthymic patients with bipolar disorder. J Affect Disord. 2006;93:105–15.

Rosenfeld RD, Zeni L, Haniu M, Talvenheimo J, Radka SF, Bennett L, Miller JA, Welcher AA. Purification and identification of brainderived neurotrophic factor from human serum. Protein Expression and Purification 6(4):465-471, 1995

Rotondo A, Mazzanti C, Dell’Osso L, Rucci P, Sullivan P, Bouanani S, et al. Catechol o-methyltransferase, serotonin transporter, and tryptophan hydroxylase gene polymorphisms in bipolar disorder patients with and without comorbid panic disorder. Am J Psychiatry (2002) 159:23–910.1176/appi.ajp.159.1.23

Ruderfer DM, Kirov G, Chambert K, Moran JL, Owen MJ, O’donovan MC, et al. A family-based study of common polygenic variation and risk of schizophrenia. Mol Psychiatry (2011) 16:887– 810.1038/mp.2011.34

Ruderfer DM, Fanous AH, Ripke S, Mcquillin A, Amdur RL, Schizophrenia Working Group of the Psychiatric Genomics C, et al. Polygenic dissection of diagnosis and clinical dimensions of bipolar disorder and schizophrenia. Mol Psychiatry (2013).10.1038/mp.2013.138

Rybakowski JK, Suwalska A, Czerski PM, Dmitrzak-Weglarz M, Leszczynska-Rodziewicz A, Hauser J. Prophylactic effect of lithium in bipolar affective illness may be related to serotonin transporter genotype. Pharmacol Rep (2005) 57:124–7

(17)

59

Rybakowski JK, Borkowska A, Skibinska M, Szczepankiewicz A, Kapelski P, Leszczynska-Rodziewicz A, et al. Prefrontal cognition in schizophrenia and bipolar illness in relation to Val66Met polymorphism of the brain-derived neurotrophic factor gene. Psychiatry Clin Neurosci (2006) 60:70–610.1111/j.1440-1819.2006.01462.x

Sachs G, Schaffer M, Winklbaur B. Cognitive deficits in bipolar disorder. Neuropsychiatr. 2007;21(2):93-101.

Salehi A, Pool CW, Mulder M, Ravid R, Gonatas NK, Swaab DF. Activity of Hippocampal CA1 Neurons in Alzheimer's Disease is not Affected by the Presence of Adjacent Neuritic Plaques. Journal of Alzheimers Disease 1(2):107-118, 1998

Samamé C, Martino DJ, Strejilevich SA. Social cognition in euthymic bipolar disorder: systematic review and meta-analytic approach. Acta Psychiatr Scand. 2012;125:266–280.

Sapolski RM. Why stress is bad for your brain. Science 273:749-750, 1996

Sapolski RM. Stress, glucocorticoids, and damage to the nervous system: The current state of confusion. Stress 1:1-19, 1996

Saykin AJ, Gur RC, Gur RE, Mozley PD, Mozley LH, Resnick SM, Kester DB, Stafiniak P. Neuropsychological function in schizophrenia. Selective impairment in memory and learning. Arch Gen Psychiatry. 1991;48:618–624. doi: 10.1001/archpsyc.1991.01810310036007.

Serretti A, Benedetti F, Mandelli L, Calati R, Caneva B, Lorenzi C, et al. Association between GSK-3beta -50T/C polymorphism and personality and psychotic symptoms in mood disorders. Psychiatry Res (2008) 158:132–4010.1016/j.psychres.2007.06.017

Serretti A, Mandelli L. The genetics of bipolar disorder: genome ‘hot regions,’ genes, new potential candidates and future directions. Mol Psychiatry (2008) 13:742–7110.1038/mp.2008.29

Shi J, Wittke-Thompson JK, Badner JA, Hattori E, Potash JB, Willour VL, et al. Clock genes may influence bipolar disorder susceptibility and dysfunctional circadian rhythm. Am J Med Genet B Neuropsychiatr Genet (2008) 147B:1047–5510.1002/ajmg.b.30714

Shimizu E, Hashimoto K, Okamura N, Koike K, Komatsu N, Kumakiri C, Nakazato M, Watanabe H, Shinoda N, Okada S, Iyo M. Alterations of serum levels of brain-derived neurotrophic factor (BDNF) in depressed patients with or without antidepressants. Biological Psychiatry 54:70-75, 2003

Skibinska M, Hauser J, Czerski PM, Leszczynska-Rodziewicz A, Kosmowska M, Kapelski P, et al. Association analysis of brainderived neurotrophic factor (BDNF) gene Val66Met polymorphism in schizophrenia and bipolar affective disorder. World Journal of Biological Psychiatry 5(4):215-220, 2004

Sklar P, Gabriel SB, McInnis MG, Bennett P, Lin Y-M, Tsan G, Schaffner S, Kirov G, Jones I, Owen M, Craddock N, DePaulo JR, Lander ES. Family-based association study of 76 candidate genes in bipolar disorder: BDNF is a potential risk locus. Molecular Psychiatry 7:579 -593, 2002

(18)

60

Smith, MA, Makino S, Kvetnansky R, Post RM. Stress and glucocorticoids affect the expression of brain-derived neurotropic factor and neurotrophin-3 mRNAs in the hippocampus. Journal of Neuroscience 15:1768- 1777, 1995

Smith MA, Makino S, Kvetnansky R, Post RM. Stress alters the expression of brainderived neurotrophic factor and neurotrophin-3 mRNAs in the hippocampus. Journal of Neuroscience 15:1768 -1777, 1995

Söderlund J, Olsson SK, Samuelsson M, Walther-Jallow L, Johansson C, Erhardt S, et al. Elevation of cerebrospinal fluid interleukin-1ss in bipolar disorder. J Psychiatry Neurosci (2011) 36:114– 810.1503/jpn.100080

Soeiro-de-Souza MG, Andreazza AC, Carvalho AF, Machado-Vieira R, Young LT, Moreno RA. Number of manic episodes is associated with elevated DNA oxidation in bipolar I disorder. Int J Neuropsychopharmacol (2013) 16:1505–1210.1017/S1461145713000047

Soeiro-de-Souza MG, Bio DS, Dias VV, Vieta E, Machado-Vieira R, Moreno RA. The CACNA1C risk allele selectively impacts on executive function in bipolar type I disorder. Acta Psychiatr Scand (2013) 128:362–910.1111/acps.12073

Sokolov BP. Oligodendroglial abnormalities in schizophrenia, mood disorders and substance abuse. Comorbidity, shared traits, or molecular phenocopies? Int J Neuropsychopharmacol (2007) 10:547– 5510.1017/S1461145706007322

Sole B, Bonnin CM, Torrent C, Martinez-Aran A, Popovic D, et al. . Neurocognitive impairment across the bipolar spectrum. CNS Neurosci Ther 18: 194–200 (2012)

Strakowski SM, DelBello MP, Adler CM. The functional neuroanatomy of bipolar disorder: a review of neuroimaging findings. Molecular Psychiatry. 2005;10:105–116.

Strakowski SM, Eliassen JC, Lamy M, et al. fMRI brain activation in bipolar mania: Evidence for disruption of the ventrolateral prefrontal-amygdala emotional pathway. Biol Psychiatry. 2011;69:381–388.

Strakowski SM, Adler CM, Almeida J, Altshuler LL, Blumberg HP, Chang KD, et al. The functional neuroanatomy of bipolar disorder: a consensus model. Bipolar Disord (2012) 14:313– 2510.1111/j.1399-5618.2012.01022.x

Strauss J, Barr CL, George CJ, Ryan CM, King N, Shaikh S, Kovacs M, Kennedy JL. BDNF and COMT polymorphisms: relation to memory phenotypes in young adults with childhood-onset mood disorder. Neuromolecular Medicine 5(3):181-192, 2004

Studentkowski G, Scheele D, Calabrese P, Balkau F, Höffler J, Aubel T, Edel MA, Juckel G, Assion HJ. Cognitive impairment in patients with a schizoaffective disorder: a comparison with bipolar patients in euthymia. Eur J Med Res. 2010;15:70–78.

Szeszko PR, Lipsky R, Mentschel C, Robinson D, Gunduz-Bruce H, Sevy S, Ashtari M, Napolitano B, Bilder RM, Kane JM, Goldman D, Malhotra AK. BDNF Val66Met polymorphism and volume of the hippocampal formation. Molecular Psychiatry 10: 631-636, 2005

(19)

61

Tamminga CA, Stan AD, Wagner AD. The hippocampal formation in schizophrenia. Am J Psychiatry. 2010;167:1178–1193. doi: 10.1176/appi.ajp.2010.09081187.

Taylor V, MacQueen G. Associations between bipolar disorder and metabolic syndrome: A review. J Clin Psychiatry. 2006 Jul;67(7):1034-41.

Thaler NS, Sutton GP, Allen DN. Social cognition and functional capacity in bipolar disorder and schizophrenia. Psychiatry Res. 2014 Aug 27. pii: S0165-1781(14)00732-X. doi: 10.1016/j.psychres.2014.08.035.

Tiwary BK. The severity of mental disorders is linked to interaction among candidate genes. Integr Biol (Camb) (2012) 4:1096–10110.1039/c2ib20066j

Torres IJ, Boudreau VG, Yatham LN. Neuropsychological functioning in euthymic bipolar disorder: a meta-analysis. Acta Psychiatr Scand Suppl. (434):17-26. (2007)

Tramontina J, Frey BN, Andreazza AC, Zandona M, Santin A, Kapczinski F. Val66met polymorphism and serum brain-derived neurotrophic factor levels in bipolar disorder. Molecular Psychiatry. 12(3):230-231, 2007

Tsigos C, Chrousos GP. Hypothalamic-pituitary-adrenal axis, neuroendocrine factors and stress. J Psychosom Res (2002) 53:865–7110.1016/S0022-3999(02)00429-4

Tsai G, Passani LA, Slusher BS, Carter R, Kleinman JE, Coyle JT. Abnormal excitatory neurotransmitter metabolism in schizophrenic brains. Archieves of General Psychiatry 52:829–836, 1995

Vaidya VA, Marek GJ, Aghajanian GK, Duman RS. 5-HT2A receptor-mediated regulation of brain-derived neurotrophic factor mRNA in the hippocampus and the neocortex. Journal of Neuroscience 15;17(8):2785-2795, 1997

Vaidya VA, Siuciak JA, Du F, Duman RS. Hippocampal mossy fiber sprouting induced by chronic electroconvulsive seizures. Neuroscience 89:157–166, 1999

Vincze I, Perroud N, Buresi C, Baud P, Bellivier F, Etain B, et al. Association between brain-derived neurotrophic factor gene and a severe form of bipolar disorder, but no interaction with the serotonin transporter gene. Bipolar Disord (2008) 10:580–710.1111/j.1399-5618.2008.00603.x Vostrikov VM, Uranova NA, Orlovskaya DD. Deficit of perineuronal oligodendrocytes in the prefrontal cortex in schizophrenia and mood disorders. Schizophr Res (2007) 94:273– 8010.1016/j.schres.2007.04.014

Womer FY, Kalmar JH, Wang F, Blumberg HP. A ventral prefrontal-amygdala neural system in bipolar disorder: a view from neuroimaging research. Acta Neuropsychiatrica. 2009;21:228–238. Wu X., Chen PS., Dallas S., et al. Histone deacetylase inhibitors up-regulate astrocyte GDNF and BDNF gene transcription and protect dopaminergic neurons. Int J Neuropsychopharrnacol. 2008;11:1123–1134.

Yasuda S., Liang MH., Marinova Z., Yahyavi A., Chuang DM. The mood stabilizers lithium and valproate selectively activate the promoter IV of brain-derived neurotrophic factor in neurons. Mol Psychiatry. 2009;14:51–59.

(20)

62

Yoshimura R, Nakano Y, Hori H, Ikenouchi A, Ueda N, Nakamura J. Effect of risperidone on plasma catecholamine metabolites and brainderived neurotrophic factor in patients with bipolar disorders. Human Psychopharmacology 21(7):433-438, 2006

Yoshimura Y, Okamoto Y, Onoda K, Okada G, Toki S, Yoshino A, Yamashita H, Yamawaki S. Psychosocial functioning is correlated with activation in the anterior cingulate cortex and left lateral prefrontal cortex during a verbal fluency task in euthymic bipolar disorder: a preliminary fMRI study. Psychiatry Clin Neurosci. 2014 Mar;68(3):188-96.

Yukimasa T, Yoshimura R, Tamagawa A, Uozumi T, Shinkai K, Ueda N, Tsuji S, Nakamura J. High-frequency repetitive transcranial stimulation improves refractory depression by influencing catecholamine and brain-derived neurotrophic factors. Pharmacopsychiatry 39(2):52-59, 2006 Zanardini R, Gazzoli A, Ventriglia M, Perez J, Bignotti S, Rossini PM,Gennarelli M, Bocchio-Chiavetto L. Effect of repetitive transcranial magnetic stimulation on serum BDNF factor in drug resistant depressed patients. Journal of Affective Disorders 91(1):83-86, 2006

Ziegenhorn AA, Schulte-Herbruggen O, Danker-Hopfe H, Malbrane M, Hartung HD, Anders D, Lang UE, Steinhagen-Thiessen E, Schaub RT, Hellweg R. Serum neurotrophins: a study on the time course and influencing factors in a large old age sample. Neurobiological Aging 28:1436-1445, 2007

Riferimenti

Documenti correlati

L' omicidio e la sua investigazione è un libro di Guglielmo Gulotta , Isabella Merzagora Betsos pubblicato da Giuffrè nella collana Psicologia giuridica e criminale: acquista su IBS

Serventes, ton lengage Sirventese, il tuo linguaggio entendra mielz neis q’eu no faz comprenderà meglio di quanto non feci io mos segner, cui es Monferraz, il

For these objects, the physical characterization is essential to define a successful mitigation mission, therefore ground-based surveys like

Facendo riferimento solo al caso di SNR peggiore, MCC migliore è raggiunta da SWTTEO che è anche il più robusto (Fig.6.46).. L’algoritmo migliore in questo caso è SNEO

Three criteria define tetrads: ( a ) a complete tetrad is composed of four large membrane particles positioned at the corners of squares with a distance of 17 to 18 nm between

Figure 12b - Cost-effectiveness analysis results in comparison of Baseline scenario and Policy scenario (costs data in billions of euro, effectiveness data in Mt

Accordo di Programma Ministero dello Sviluppo Economico – ENEA Area: Produzione e fonti energetiche. Tema: Nuovo Nucleare

The estimated contact resistance is the sum of three different terms: current leads copper resistance, Indium resistance (Indium is placed between the contact