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MOH 1 SG-2018-

12368279

Skin-to-skin contact in NICU, caregiving touch and neural correlates of slow stroking touch stimulation in preterm infants. A MRI study.

7,25 Biobehavioral and Behavioral Processes

Pediatria MEDEA € 130.000,00 € 130.000,00 € 4.870.000,00

2 SG-2018- 12367518

Exploring the potential of epigenetic drugs in tuning telomere homeostasis to restrain aggressiveness of high grade thyroid cancer

7,50 Oncology 1 - Basic Translational

Oncologia AUSL RE Ist. Tecnologie Avanzate

€ 130.000,00 € 130.000,00 € 4.740.000,00

3 SG-2018- 12368175

Active Navigation Training: An Innovative Embodied- Based Training System For Spatial Navigation In Aging

8,00 Biobehavioral and Behavioral Processes

Geriatria AUXOLOGICO € 130.000,00 € 130.000,00 € 4.610.000,00

4 SG-2018- 12366194

A more accurate risk biomarkers recognition for progressive multifocal leukoencephalopathy (PML) caused by Polyomavirus JC in patients with multiple sclerosis during treatment with disease-modifying therapies (DMTs): an ongoing clinical challenge.

8,00 Infectious Diseases and Microbiology

Malattie Infettive SAN RAFFAELE PISANA € 130.000,00 € 130.000,00 € 4.480.000,00

5 SG-2018- 12365675

ASSESSMENT OF GENETIC FACTORS MODIFYING THE CLINICAL PHENOTYPE IN SEVERE RARE DISORDERS: ALEXANDER DISEASE AS A MODEL

8,00 Genes, Genomes and Genetics

Neurologia GASLINI € 130.000,00 € 130.000,00 € 4.350.000,00

6 SG-2018- 12367471

Novel and non-invasive diagnostic and prognostic biomarkers for Neurofibromatosis type 1 and related cancers: expression profiling of serum circulating miRNAs and patho-physiological implications.

8,25 Oncology 2 - Translational Clinical

Neurologia Campania € 130.000,00 € 130.000,00 € 4.220.000,00

7 SG-2018- 12367059

A new strategy to address tumor relapses by

nanostructured implantable devices 9,00 Bioengineering Sciences and Technologies

Ortopedia RIZZOLI € 130.000,00 € 130.000,00 € 4.090.000,00

8 SG-2018- 12367646

The adenosine receptor agonist

Polydeoxyribonucleotide (PDRN) as a possible anti- psoriatic agent.

9,50 Immunology Dermatologia Sicilia € 130.000,00 € 130.000,00 € 3.960.000,00

9 SG-2018- 12367995

An integrated clinical and genetic approach to

corpus callosum abnormalties. 9,50 Brain Disorders and Clinical Neuroscience

Neurologia Campania € 130.000,00 € 130.000,00 € 3.830.000,00

10 SG-2018- 12366731

In vivo imaging of macro-environment before tumor appearance: a novel approach to identify early tumor biomarkers in pancreatic cancer.

9,50 Oncology 2 - Translational Clinical

Oncologia REGINA ELENA € 130.000,00 € 130.000,00 € 3.700.000,00

11 SG-2018- 12367244

Xlr gene as a new candidate for cocaine addiction

susceptibility 9,50 Brain Disorders and Clinical

Neuroscience

Malattie Psichiatriche SANTA LUCIA € 123.000,00 € 123.000,00 € 3.577.000,00

12 SG-2018- 12368253

Characterization of Nucleophosmin-associated microRNAs in the regulation of inflammatory mechanisms involved in psoriasis pathogenesis

10,00 Musculoskeletal, Oral and Skin Sciences

Dermatologia ISTITUTO DERMOPATICO DELL'IMMACOLATA

€ 130.000,00 € 130.000,00 € 3.447.000,00

(2)

MOH 13 SG-2018-

12368288

Efficacy of Cognitive Behavioral Therapy in Psychogenic Non-Epileptic Seizures (PNES) patients:

towards the creation of a dedicated center for diagnosis and care for avoiding health migration outside Calabria and cutting healthcare costs.

10,00 Brain Disorders and Clinical Neuroscience

Neurologia Calabria € 130.000,00 € 130.000,00 € 3.317.000,00

14 SG-2018- 12367867

SLC7A8 a novel gene involved in late-onset hearing

loss: from functional studies to drug discovery. 10,50 Genes, Genomes and Genetics

Diagnostica BURLO GAROFOLO € 130.000,00 € 130.000,00 € 3.187.000,00

15 SG-2018- 12367527

Efficacy of repetitive Transcranial Magnetic Stimulation (r-TMS) combined with visual scanning treatment on cognitive-behavioral symptoms of unilateral spatial neglect in patients with traumatic brain injury: a randomized clinical trial

10,75 Brain Disorders and Clinical Neuroscience

Neurologia Emilia-Romagna € 130.000,00 € 130.000,00 € 3.057.000,00

16 SG-2018- 12366369

Biomimetic antimicrobial biliary stent coated by graphene oxide to prevent biofilm formation and stent occlusion

10,75 Bioengineering Sciences and Technologies

Malattie Infettive FONDAZIONE GEMELLI € 129.200,00 € 129.200,00 € 2.927.800,00

17 SG-2018- 12367839

Insights in Progressive Myoclonic Epilepsies Using

Zebrafish as a Tool 11,00 Brain Disorders and Clinical

Neuroscience

Neurologia STELLA MARIS € 130.000,00 € 130.000,00 € 2.797.800,00

18 SG-2018- 12366233

p75NTR polymorphisms as genetic risk factors for

Alzheimer's Disease 11,00 Biobehavioral and

Behavioral Processes

Neurologia Calabria € 130.000,00 € 130.000,00 € 2.667.800,00

19 SG-2018- 12366917

Mi-RNAs as potential predictive biomarkers for early

diagnosis of hepatocellular carcinoma 11,00 Infectious Diseases and Microbiology

Oncologia PASCALE € 130.000,00 € 130.000,00 € 2.537.800,00

20 SG-2018- 12366261

Pre B cell leukemia homeobox 1 (Pbx1) as a novel

player in myeloproliferative neoplasms. 11,25 Vascular and Hematology Ematologia e

Immunologia HUMANITAS € 130.000,00 € 130.000,00 € 2.407.800,00 21 SG-2018-

12367132

High prevalence of Merkel cell carcinoma in autoimmune disease affected patients treated with biological drugs

11,50 Oncology 2 - Translational Clinical

Oncologia Emilia-Romagna € 130.000,00 € 130.000,00 € 2.277.800,00

22 SG-2018- 12368232

Gait-tailored brain electroceutical therapy in

Parkinson's disease 11,50 Brain Disorders and Clinical

Neuroscience

Neurologia Liguria € 125.580,00 € 125.580,00 € 2.152.220,00

23 SG-2018- 12368345

Implementation of Whole Exome Sequencing for the aetiologic diagnosis of Intellectual

Disability/Autism/Congenital malformations syndromes for management, prognosis, therapy, and prevention in families.

11,50 Genes, Genomes and Genetics

Diagnostica Umbria € 130.000,00 € 130.000,00 € 2.022.220,00

24 SG-2018- 12366101

Sensorimotor impairments related to cognitive deficits in Alzheimer's disease: a novel diagnostic tool

11,75 Brain Disorders and Clinical Neuroscience

Diagnostica Lazio € 130.000,00 € 130.000,00 € 1.892.220,00

25 SG-2018- 12367994

Role of HtrA1 in Preeclampsia: A Possible Marker? 12,00 Endocrinology, Metabolism, Nutrition and Reproductive Sciences

Ostetricia e

Ginecologia Marche € 128.700,00 € 128.700,00 € 1.763.520,00

(3)

MOH 26 SG-2018-

12365617

3R4Rabies: An innovative way to replace in vivo experiments for rabies diagnostic interlaboratory trials with sustainable in vitro systems

12,00 Veterinary Malattie Infettive IZSVE € 130.000,00 € 130.000,00 € 1.633.520,00

27 SG-2018- 12365241

Gene therapy for Wiskott-Aldrich syndrome (WAS):

the impact of intestinal microbiota on clinical outcomes

12,00 Immunology Ematologia e

Immunologia SAN RAFFAELE MILANO € 130.000,00 € 130.000,00 € 1.503.520,00

28 SG-2018- 12368028

Computational and Predictive Modeling in Young

Patients with Cryptogenic Cerebrovascular Events 12,50 Vascular and Hematology Ematologia e

Immunologia Piemonte € 126.400,00 € 126.400,00 € 1.377.120,00

29 SG-2018- 12367719

Differential Diagnosis between Borderline Personality Disorder and Bipolar Disorder:

psychopathology, neuroimaging and course in young adults referring to Community Mental Health Services.

12,50 Biobehavioral and Behavioral Processes

Malattie Psichiatriche Emilia-Romagna € 130.000,00 € 130.000,00 € 1.247.120,00

30 SG-2018- 12366226

Modulating the ATP - purinoreceptor P2X7 signaling in the skeletal muscles of SOD1G93A mice as a ground-breaking strategy to hinder the progression of Amyotrophic Lateral Sclerosis

12,50 Brain Disorders and Clinical Neuroscience

Neurologia MARIO NEGRI € 130.000,00 € 130.000,00 € 1.117.120,00

31 SG-2018- 12366548

Biological strategy to enhance the therapeutic effect of Stromal Vascular Fraction for the treatment of osteoarthritis

12,50 Musculoskeletal, Oral and Skin Sciences

Ortopedia GALEAZZI € 130.000,00 € 130.000,00 € 987.120,00

32 SG-2018- 12367167

Towards a powerful tool for the stratification of Amyotrophic Lateral Sclerosis patients: salivary biomarkers detection by the combination of Raman Spectroscopy and MALDI-TOF spectrometry.

13,00 Emerging Technologies and Training in Neurosciences

Neurologia DON GNOCCHI € 130.000,00 € 130.000,00 € 857.120,00

33 SG-2018- 12368019

Clinical, neuroradiological and neurophysiological

features of a population based iRBD cohort. 13,50 Brain Disorders and Clinical Neuroscience

Neurologia Sicilia € 129.934,00 € 129.934,00 € 727.186,00

34 SG-2018- 12366201

Study of circulating nucleic acids for early detection

of hepatocellular carcinoma 13,50 Oncology 2 - Translational Clinical

Diagnostica PASCALE € 130.000,00 € - € 727.186,00 secondo progetto stesso destinatario istituzionale

35 SG-2018- 12365432

Fecal microRNAs potential biomarkers of pediatric celiac disease and study of phenotypic and genotypic characteristics of Escherichia coli for disease classification

13,50 Digestive, Kidney and Urological Systems

Gastroenterologia OSPEDALE BAMBINO GESU'

€ 130.000,00 € 130.000,00 € 597.186,00

36 SG-2018- 12365204

Study of the metastatic microenvironment in colorectal cancer: role of cancer-associated fibroblasts (CAFs) in chemotherapy resistance

13,50 Oncology 1 - Basic Translational

Oncologia Istituto Superiore di Sanita'

€ 130.000,00 € 130.000,00 € 467.186,00

37 SG-2018- 12366446

Epi-metabolic drug design and characterization to prevent or ameliorate fibrosis in human diseased cellular systems

13,75 Interdisciplinary Molecular Sciences and Training

Riabilitazione MAUGERI € 130.000,00 € 130.000,00 € 337.186,00

(4)

MOH 38 SG-2018-

12367304

Cost-effectiveness analysis of screening programs

for Lynch syndrome in Italy. 14,00 Population Sciences and Epidemiology

Gastroenterologia FONDAZIONE GEMELLI € 102.500,00 € - € 337.186,00 secondo progetto stesso destinatario istituzionale

39 SG-2018- 12368367

The effectiveness and safety profile of atomoxetine and metilphenidate in children and adolescents diagnosed with ADHD. An observational study.

14,00 Biobehavioral and Behavioral Processes

Pediatria Campania € 130.000,00 € 130.000,00 € 207.186,00

40 SG-2018- 12368216

Effects of Mindfulness Training on quality of life of Patients with Alzheimer's disease and their Caregivers.

14,00 Risk, Prevention and Health Behavior

Geriatria I.N.R.C.A. € 120.300,00 € 120.300,00 € 86.886,00

41 SG-2018- 12368062

Effectiveness of strategy-adaptation memory training in healthy older adults and in amnestic mild cognitive impairment patients: effects on everyday tasks, individual differences, and functional brain changes.

14,50 Biobehavioral and Behavioral Processes

Riabilitazione MONDINO € 112.870,00 € -

42 SG-2018- 12367520

Promoting recovery in patients with Disorders of Consciousness by modulating the afferent spinal- cortical pathway: controlled trials on combined effects of trans-spinal electric stimulation and Sensory Regulation.

14,50 Brain Disorders and Clinical Neuroscience

Riabilitazione MAUGERI € 126.700,00 € -

43 SG-2018- 12367947

FAMILIAL CEREBROVASCULAR MALFORMATIONS:

FUNCTIONAL VALIDATION OF VARIANTS IN NOVEL CANDIDATE GENES IDENTIFIED BY WHOLE EXOME SEQUENCING ANALYSIS

14,50 Genes, Genomes and Genetics

Neurologia Sicilia € 130.000,00 € -

44 SG-2018- 12365202

Multi-parametric prediction model for adverse perinatal outcome integrating prenatal ultrasound, micro RNA and extracellular vesicles analysis in pregnancies at term

14,50 Risk, Prevention and Health Behavior

Ostetricia e

Ginecologia Abruzzo € 130.000,00 € -

45 SG-2018- 12365849

Pathophysiology of PCDH19-related epilepsy modeling cortical neurons using human induced pluripotent stem cells: implications for therapy.

14,75 Brain Disorders and Clinical Neuroscience

Neurologia OSPEDALE BAMBINO

GESU'

€ 130.000,00 € -

46 SG-2018- 12368370

Integrated and Personalized approach for Return to

Work after Knee Replacement 14,75 Musculoskeletal, Oral and Skin Sciences

Ortopedia INAIL € 130.000,00 € -

47 SG-2018- 12368394

Risk minimization of potentially inappropriate preScripTions for ELderLy patients in CAmpania Region (STELLAR)

15,00 Healthcare Delivery and Methodologies

Geriatria Campania € 130.000,00 € -

48 SG-2018- 12368117

Identification of pathogenic genes in hereditary angioedema with normal C1 inhibitor by means of next generation sequencing (NGS)

15,00 Genes, Genomes and Genetics

Diagnostica Puglia € 129.200,00 € -

49 SG-2018- 12368398

Identification of genetic and environmental risk factors for Age-Related Hearing Loss to the development of personalized therapies

15,00 Biology of Development and Aging

Otorinolaringoiatria e

Odontoiatria FONDAZIONE GEMELLI € 130.000,00 € -

(5)

MOH 50 SG-2018-

12368393

Epigenetic changes in Myasthenia Gravis (EPIMYA) 15,00 Genes, Genomes and Genetics

Neurologia Toscana € 130.000,00 € -

51 SG-2018- 12366680

Polyphenol enriched extra-virgin olive oil and postprandial glucose response in patients with type 1 diabetes: possible effects and mechanisms

15,50 Endocrinology, Metabolism, Nutrition and Reproductive Sciences

Endocrinologia Campania € 130.000,00 € -

52 SG-2018- 12366237

Three-dimensional patient-derived organotypic model of colorectal cancer liver metastasis as an in vitro model of liver metastatic colonization

15,50 Oncology 1 - Basic Translational

Oncologia Veneto € 129.500,00 € -

53 SG-2018- 12366697

Epigenetics of coronary artery disease (CAD):

identification of new molecular biomarkers for the risk stratification of CAD patients, early diagnosis of acute myocardial infarction and personalized medicine.

15,50 Genes, Genomes and Genetics

Cardiologia-

Pneumologia Lazio € 130.000,00 € -

54 SG-2018- 12366595

Therapeutic use of integrase defective lentiviral vectors for improving epigenetic drug therapy in metastatic melanoma

16,00 Oncology 2 - Translational Clinical

Oncologia Istituto Superiore di Sanita'

€ 130.000,00 € -

55 SG-2018- 12366755

Nutritional support in spine surgery 16,00 Healthcare Delivery and Methodologies

Ortopedia GALEAZZI € 130.000,00 € -

56 SG-2018- 12367370

Genetic and Molecular pathway marks as the base for specific phenotypic manifestations in psychiatric disorders.

16,50 Brain Disorders and Clinical Neuroscience

Malattie Psichiatriche Sicilia € 130.000,00 € -

57 SG-2018- 12367985

Preventative gynaecological surgery in women with

colorectal cancer. 16,50 Interdisciplinary Molecular

Sciences and Training

Ostetricia e

Ginecologia PASCALE € 130.000,00 € -

58 SG-2018- 12366898

Role of tumor matrix density in cell division and

chromosomal instability 16,50 Oncology 1 - Basic

Translational

Oncologia REGINA ELENA € 130.000,00 € -

59 SG-2018- 12365632

A novel therapeuticl approach to prevent pathological corneal angiogenesis: the role of mesenchymal stem cell - derived extracellular vesicle

16,50 Vascular and Hematology Oculistica Veneto € 130.000,00 € -

60 SG-2018- 12366537

Cancer-specific ultraconserved long noncoding RNA 8 as a novel biomarker for bladder cancer detection and prognosis

17,00 Oncology 2 - Translational Clinical

Oncologia Lazio € 130.000,00 € -

61 SG-2018- 12366397

Serum Vitamin E, telomere/telomerase system and

immune system in Alzheimer's disease 17,00 Biology of Development and Aging

Geriatria Umbria € 130.000,00 € -

62 SG-2018- 12367586

The role of FGF23 axis in the management of chronic

HF patients 18,00 Cardiovascular and

Respiratory Sciences

Cardiologia-

Pneumologia Toscana € 130.000,00 € - 63 SG-2018-

12368283

A comprehensive investigation on the influencing factors that potentially alter the direct biomarkers, in hair samples, of ethanol consumption for the assessment of harmful drinking.

18,00 Risk, Prevention and Health Behavior

Diagnostica Piemonte € 128.602,00 € -

(6)

MOH 64 SG-2018-

12368260

A Novel Filling Material to Improve Dental Outcomes

in Pediatric Special Needs Patients 18,50 Musculoskeletal, Oral and Skin Sciences

Otorinolaringoiatria e

Odontoiatria Umbria € 130.000,00 € - 65 SG-2018-

12366597

Correlation between APOBEC, PD-L1 and PD-L2 expression, MSI, clinic-pathological features and overall survival in resected gastric cancer: looking for prognostic and predictive biomarkers

18,50 Oncology 2 - Translational Clinical

Oncologia Lombardia € 130.000,00 € -

66 SG-2018- 12367895

OVARIAN TOXICITY INDUCED BY ANTICANCER DRUGS: A POTENTIAL TRANSLATIONAL APPROACH TOWARDS STRATEGIES FOR PRESERVING REPRODUCTIVE HEALTH IN CANCER PATIENTS

19,50 Endocrinology, Metabolism, Nutrition and Reproductive Sciences

Ostetricia e

Ginecologia REGINA ELENA € 129.900,00 € -

67 SG-2018- 12366080

Characterization of vascular proteoglycans as a new

tool to identify subjects at higher cardiovascular risk 19,50 Vascular and Hematology Diagnostica Sicilia € 130.000,00 € -

68 SG-2018- 12368197

Identifying DNA methylation profiles predicting

protective response to vaccination 19,50 Immunology Malattie Infettive OSPEDALE BAMBINO

GESU'

€ 130.000,00 € -

69 SG-2018- 12367474

A novel mouse model to study the pathophysiology

of adipose tissue 20,50 Endocrinology, Metabolism,

Nutrition and Reproductive Sciences

Endocrinologia SAN RAFFAELE PISANA € 130.000,00 € -

70 SG-2018- 12367130

THE IMPACT ON TISSUE REPAIR AND PATIENT LIFE QUALITY OF PRP (PLATELET-RICH PLASMA) AUTHOLOGOUS INJECTIONS IN PENILE AND VULVAR LICHEN SCLEROSUS: A COMPARATIVE ANALYSIS IN MALE AND FEMALE.

21,25 Musculoskeletal, Oral and Skin Sciences

Dermatologia SAN GALLICANO € 130.000,00 € -

71 SG-2018- 12365547

Pro and anti-tumorigenic pathways in melanoma:

role of alpha-MSH 21,25 Cell Biology Dermatologia SAN GALLICANO € 130.000,00 € -

72 SG-2018- 12366139

A facilitator to break down the barriers to physical activity of chronic kidney disease patients. An implementation trial in a Nephrology Unit

21,50 Risk, Prevention and Health Behavior

Riabilitazione Emilia-Romagna € 130.000,00 € -

73 SG-2018- 12365124

Targeting tumor-associated macrophages and regulators of epithelial-mesenchymal transition as a novel therapeutic approach for the treatment of metastatic dissemination and dormancy of triple- negative breast cancer

22,00 Oncology 1 - Basic Translational

Oncologia I. O. V. € 130.000,00 € -

74 SG-2018- 12366483

Effects of Probiotic supplementation on glycan composition of mucins secreted by Brunner's glands . Experimental study in small laboratory animals.

22,00 Digestive, Kidney and Urological Systems

Gastroenterologia DE BELLIS € 130.000,00 € -

(7)

MOH 75 SG-2018-

12366506

Apoptotic bodies and their cargo as new biomarkers and mediators of diabetes-induced endothelium dysfunction

23,00 Endocrinology, Metabolism, Nutrition and Reproductive Sciences

Endocrinologia SAN RAFFAELE PISANA € 130.000,00 € -

76 SG-2018- 12367903

Carbonyl reductase 1 inhibitors to overcome the intrinsic oxidative stress resistance in human gastrointestinal cancers, to use in combination therapy with ROS-inducing anticancer drug Doxorubicin.

26,25 Oncology 2 - Translational Clinical

Oncologia C.R.O. AVIANO € 130.000,00 € -

77 SG-2018- 12368330

Neurophysiological and cognitive effects of a Virtual

Reality Interactive Avatar in girls with Rett Syndrome 27,00 Emerging Technologies and Training in Neurosciences

Neurologia NEUROLESI € 126.000,00 € -

78 SG-2018- 12368366

Risk of venous thromboembolic event (VTE) among women co-exposed with a hormonal contraceptive (HC) and non-steroidal ant-inflammatory drugs (NSAIDs): a register-based cohort study

27,00 Endocrinology, Metabolism, Nutrition and Reproductive Sciences

Ostetricia e

Ginecologia Campania € 130.000,00 € -

79 SG-2018- 12365688

Characterization of the role of ghrelin and des-acyl ghrelin in determining growth defects and other adverse events observed in children maintained on the ketogenic diet.

29,50 Brain Disorders and Clinical Neuroscience

Pediatria Emilia-Romagna € 130.000,00 € -

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