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 Identificare marker biochimici di eccesso di cortisolo che predicono possibili danni d’organo

 Valutare mediante l’utilizzo della spettrometria di massa per la misura dei metaboliti intermedi se nel tempo alcuni adenomi surrenalici non funzionanti acquisiscono capacità secernenti

 Poter identificare la classe di pazienti a maggior rischio evolutivo

 Poter definire con certezza il tipo di trattamento ottimale se conservativo o chirurgico  Definire i costi effettivi dei protocolli di follow up, l’utilità e la necessità

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RINGRAZIAMENTI

Per la realizzazione di questa tesi di laurea ringrazio sentitamente il Prof. Massimo Tonacchera per i suoi insegnamenti e per la sua disponibilità.

Ringrazio la dott.ssa Francesca Orsolini, estremamente educata, disponibile e capace, per avermi seguita nella realizzazione di questo elaborato e avermi dato i giusti consigli, così come ringrazio anche il dott. Angelo Molinari per le sue conoscenze e i suggerimenti che mi ha dato. Un pensiero speciale è rivolto verso i miei genitori, nonché mio orgoglio, avendomi sempre accompagnato nei momenti importanti della vita.

Anche se non sarà mai abbastanza, voglio ringraziare:

mia madre per avermi ascoltata e incoraggiata nei momenti di ansia e preoccupazione, per aver

sempre trovato le giuste parole di conforto e motivazione e per aver creduto in me e nelle mie capacità;

e mio padre per essere sempre stato la mia colonna portante in tutti questi anni, come del resto continuerà ad esserlo, e per l’instancabile sostegno sia morale sia economico che mi ha permesso di arrivare fin qui, contribuendo alla mia formazione personale.

Altrettanto, un tenero pensiero è rivolto verso i miei nonni e zii che hanno sempre speso belle parole di incoraggiamento nei miei confronti.

A Marco, che con la sua spontaneità e leggerezza ha saputo supportarmi e “sopportarmi” durante tutti questi anni di studio. Molti sono i suoi pregi, ma tra i tanti, voglio riconoscergli il merito di avermi ascoltata e rincuorata nei miei momenti più difficili.

Un grazie di cuore, anche se uno solo non basta, alle mie amiche e compagne di corso Francesca, Arianna e Beatrice per esserci sempre state, anche nei momenti di sconforto. L’amicizia nata tra di noi in questi anni è stata una splendida scoperta. Senza di loro non sarebbe stata la stessa cosa; ci siamo sempre incoraggiate a vicenda come una “vera squadra”. Grazie alla loro costante e quotidiana presenza, ad oggi sono uno dei motivi principali per cui sono riuscita a portare a termine questo percorso di studi.

Infine, ma non certo per importanza, un ringraziamento speciale a tutti i miei amici che hanno preso parte alla mia vita in questi anni e che ha contribuito alla realizzazione di questo primo traguardo del mio percorso di vita.

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